Motif ID: LHX3,4.p2

Z-value: 0.827


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LHX4chr1_+_178466064-0.476.4e-02Click!
LHX3chr9_-_138234707-0.273.2e-01Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_52697160 1.185 HOXC5
HOXC6
homeobox C5
homeobox C6
chr13_-_45323757 0.995 NM_198849
 SIAH3
seven in absentia homolog 3 (Drosophila)
chr7_-_122627235 0.961 NM_022444
 SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr8_-_62764839 0.956 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
 ASPH






aspartate beta-hydroxylase






chr6_-_66346417 0.948 NM_198283
 EYS
eyes shut homolog (Drosophila)
chr8_-_131483395 0.914 NM_018482
 ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr10_-_33264491 0.868 NM_033668
 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr22_-_38619739 0.859 NM_152512
 ENTHD1
ENTH domain containing 1
chr12_+_52696908 0.846 NM_014620
NM_153693
 HOXC4
HOXC6
homeobox C4
homeobox C6
chr10_+_102212787 0.813 NM_003393
 WNT8B
wingless-type MMTV integration site family, member 8B
chr8_+_32905027 0.728


chr1_+_157526127 0.712 NM_002001
 FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr15_+_92700167 0.701 NM_001159644
 MCTP2
multiple C2 domains, transmembrane 2
chr9_-_137671206 0.699 NM_182974
 GLT6D1
glycosyltransferase 6 domain containing 1
chr9_+_4829763 0.696 RCL1
RNA terminal phosphate cyclase-like 1
chr15_+_46271158 0.675 NM_001145668
 CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr12_-_88573949 0.663 NM_001001323
NM_001682
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr4_+_71054492 0.662 NM_214711
 C4orf40
chromosome 4 open reading frame 40
chr18_+_59733724 0.662 NM_005024
 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr3_-_69212192 0.656 NM_003968
NM_198195
 UBA3

ubiquitin-like modifier activating enzyme 3


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.08 1.94e-12 GO:0007608 sensory perception of smell
2.89 1.03e-11 GO:0007606 sensory perception of chemical stimulus
2.07 5.21e-07 GO:0007600 sensory perception
1.79 7.78e-07 GO:0050877 neurological system process
1.77 1.20e-08 GO:0003008 system process
1.33 9.95e-07 GO:0032501 multicellular organismal process
1.22 3.68e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.52 3.25e-02 GO:0044430 cytoskeletal part
1.42 3.08e-09 GO:0005886 plasma membrane
1.41 6.03e-09 GO:0071944 cell periphery
1.41 4.58e-02 GO:0005856 cytoskeleton
1.23 1.15e-03 GO:0016021 integral to membrane
1.21 4.95e-03 GO:0031224 intrinsic to membrane
1.19 7.02e-03 GO:0044425 membrane part
1.16 6.26e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.18 1.72e-13 GO:0004984 olfactory receptor activity
2.29 1.47e-11 GO:0004930 G-protein coupled receptor activity
1.88 7.48e-09 GO:0004888 transmembrane receptor activity
1.71 3.31e-08 GO:0004872 receptor activity
1.64 2.09e-08 GO:0004871 signal transducer activity
1.64 2.09e-08 GO:0060089 molecular transducer activity