Motif ID: MYFfamily.p2

Z-value: 1.700


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.371.6e-01Click!
MYF5chr12_+_796348200.361.7e-01Click!
MYF6chr12_+_79625538-0.194.8e-01Click!
MYOGchr1_-_2013217110.097.4e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_137829077 3.062 NM_001964
EGR1
early growth response 1
chr12_-_74710741 2.142 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr5_+_113725914 1.867 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr5_+_137829065 1.857 EGR1
early growth response 1
chr8_+_56177567 1.569 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_-_230287442 1.223 NM_139072
DNER
delta/notch-like EGF repeat containing
chr9_-_139183675 1.118


chr16_+_4370879 1.060 VASN
vasorin
chr3_+_3816079 1.007 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr2_+_191453813 0.946 GLS
glutaminase
chr2_+_191453791 0.924 NM_014905
GLS
glutaminase
chr4_+_61749540 0.921 LPHN3
latrophilin 3
chr5_+_113726203 0.913 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr22_+_31527678 0.896 TIMP3
TIMP metallopeptidase inhibitor 3
chr9_-_139184247 0.885 NM_001013653
LRRC26
leucine rich repeat containing 26
chr3_+_128190070 0.879 NM_032242
PLXNA1
plexin A1
chr7_+_39956633 0.833 CDK13
cyclin-dependent kinase 13
chr5_-_59225377 0.832 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_59020875 0.794 JUN
jun proto-oncogene
chr3_+_151608673 0.752 TSC22D2
TSC22 domain family, member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
1.95 3.10e-02 GO:0048736 appendage development
1.95 3.10e-02 GO:0060173 limb development
1.67 1.30e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.67 1.44e-04 GO:0007411 axon guidance
1.65 7.41e-06 GO:0007409 axonogenesis
1.64 4.57e-06 GO:0048812 neuron projection morphogenesis
1.62 2.02e-06 GO:0000904 cell morphogenesis involved in differentiation
1.58 1.45e-05 GO:0048858 cell projection morphogenesis
1.57 2.57e-06 GO:0048666 neuron development
1.57 2.71e-05 GO:0032990 cell part morphogenesis
1.57 4.48e-05 GO:0031175 neuron projection development
1.56 9.37e-08 GO:0030182 neuron differentiation
1.52 1.07e-08 GO:0048699 generation of neurons
1.50 9.87e-05 GO:0000902 cell morphogenesis
1.49 8.68e-03 GO:0007268 synaptic transmission
1.48 4.90e-06 GO:0007155 cell adhesion
1.48 4.90e-06 GO:0022610 biological adhesion
1.48 4.25e-03 GO:0019226 transmission of nerve impulse
1.48 4.25e-03 GO:0035637 multicellular organismal signaling
1.47 2.16e-13 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
4.19 8.65e-03 GO:0005583 fibrillar collagen
2.56 2.22e-02 GO:0005581 collagen
2.11 3.70e-03 GO:0045095 keratin filament
2.09 9.83e-05 GO:0044420 extracellular matrix part
1.72 1.03e-07 GO:0031012 extracellular matrix
1.68 1.38e-05 GO:0005578 proteinaceous extracellular matrix
1.65 5.20e-03 GO:0034702 ion channel complex
1.52 1.39e-02 GO:0044456 synapse part
1.48 2.58e-03 GO:0045202 synapse
1.47 7.63e-03 GO:0009986 cell surface
1.30 1.81e-04 GO:0031226 intrinsic to plasma membrane
1.29 2.41e-08 GO:0044459 plasma membrane part
1.28 8.14e-04 GO:0005887 integral to plasma membrane
1.26 2.24e-02 GO:0044421 extracellular region part
1.22 3.77e-04 GO:0005576 extracellular region
1.16 1.39e-05 GO:0005886 plasma membrane
1.16 2.61e-05 GO:0071944 cell periphery
1.12 1.53e-05 GO:0044425 membrane part
1.11 2.39e-03 GO:0031224 intrinsic to membrane
1.10 1.33e-04 GO:0016020 membrane

Nothing significant found in function category.