Motif ID: PAX3,7.p2

Z-value: 0.217


Transcription factors associated with PAX3,7.p2:

Gene SymbolEntrez IDGene Name
PAX3 5077 paired box 3
PAX7 5081 paired box 7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX3chr2_-_2228715770.322.2e-01Click!
PAX7chr1_+_188300860.126.5e-01Click!


Activity profile for motif PAX3,7.p2.

activity profile for motif PAX3,7.p2


Sorted Z-values histogram for motif PAX3,7.p2

Sorted Z-values for motif PAX3,7.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX3,7.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_57385140 0.238 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385130 0.208 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385146 0.194 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385041 0.188 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385072 0.162 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_-_54857003 0.145 IRF3
interferon regulatory factor 3
chr2_+_114390975 0.084 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr19_+_57384866 0.066 NM_014225
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr7_-_103417198 0.051 NM_005045
NM_173054
RELN

reelin

chr15_-_81412354 0.048 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr9_-_90983501 0.029 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr12_+_6930799 0.027 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr10_+_92621221 0.026 RPP30
ribonuclease P/MRP 30kDa subunit
chr8_-_71146103 0.026 NM_024504
PRDM14
PR domain containing 14
chr12_+_6930792 0.023 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_6930804 0.023 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_6930778 0.018 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_6930694 0.017 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr10_+_91077581 0.016 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr14_+_23654161 0.013 DCAF11
DDB1 and CUL4 associated factor 11
chr14_-_20128228 0.012 NM_145250
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr10_+_104169560 0.010 NM_024326
FBXL15
F-box and leucine-rich repeat protein 15
chr12_+_6930815 0.007 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_-_47591949 0.005 CA10
carbonic anhydrase X
chrX_+_38305634 0.004 NM_004615
TSPAN7
tetraspanin 7
chr4_-_104338924 0.001 NM_001813
CENPE
centromere protein E, 312kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
51.55 3.56e-03 GO:0060337 type I interferon-mediated signaling pathway
51.55 3.56e-03 GO:0071357 cellular response to type I interferon
50.73 3.74e-03 GO:0034340 response to type I interferon
193.53 6.92e-03 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
5.66 4.70e-02 GO:0010033 response to organic substance

Nothing significant found in compartment category.

Nothing significant found in function category.