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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HES1.p2

Z-value: 2.039

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr20_+_11819364	5.139	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr2_+_113119985	2.354	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr12_+_8741746	2.353	NM_020734	RIMKLB	ribosomal modification protein rimK-like family member B
chr2_+_46779827	2.302	NM_144949	SOCS5	suppressor of cytokine signaling 5
chr14_+_61231795	2.152	NM_001530 NM_181054	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr2_+_182464910	2.089		SSFA2	sperm specific antigen 2
chr3_-_88190737	2.078	NM_001008390 NM_003663	CGGBP1	CGG triplet repeat binding protein 1
chr3_+_112273464	1.925	NM_015480	PVRL3	poliovirus receptor-related 3
chr7_+_93977267	1.897		CASD1	CAS1 domain containing 1
chr17_+_43082273	1.874	NM_002265	KPNB1	karyopherin (importin) beta 1
chr22_+_39817733	1.848		EP300	E1A binding protein p300
chr2_+_181553613	1.824		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr2_-_225615556	1.761	NM_014689	DOCK10	dedicator of cytokinesis 10
chr2_+_85619802	1.754		MAT2A	methionine adenosyltransferase II, alpha
chr5_+_63497408	1.743	NM_001113561 NM_178532	RNF180	ring finger protein 180
chr2_+_182464713	1.729	NM_001130445 NM_006751	SSFA2	sperm specific antigen 2
chr8_-_12657339	1.709	NM_152271	LONRF1	LON peptidase N-terminal domain and ring finger 1
chr3_+_180348818	1.535	NM_006218	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr8_+_59069522	1.532	NM_147189	FAM110B	family with sequence similarity 110, member B
chr7_+_24579239	1.453	NM_016447	MPP6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr11_+_86426518	1.448	NM_001168724 NM_022918	TMEM135	transmembrane protein 135
chr21_+_34367747	1.437		MRPS6	mitochondrial ribosomal protein S6
chr2_+_101680594	1.419	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_10042579	1.373	NM_201433	GAS7	growth arrest-specific 7
chr9_+_100907189	1.366		TGFBR1	transforming growth factor, beta receptor 1
chr17_+_43081837	1.337		KPNB1	karyopherin (importin) beta 1
chr9_+_100907222	1.334	NM_001130916 NM_004612	TGFBR1	transforming growth factor, beta receptor 1
chr10_+_120779217	1.331	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr9_+_100907213	1.316		TGFBR1	transforming growth factor, beta receptor 1
chr17_+_43082302	1.306		KPNB1	karyopherin (importin) beta 1
chr2_+_61146866	1.302	NM_032506	KIAA1841	KIAA1841
chr3_+_73128771	1.276	NM_174907	PPP4R2	protein phosphatase 4, regulatory subunit 2
chr2_+_203901160	1.272	NM_005759	ABI2	abl-interactor 2
chr7_+_93976927	1.272	NM_022900	CASD1	CAS1 domain containing 1
chr9_+_100907292	1.254
chr22_+_30670435	1.234	NM_003405	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr18_+_18969724	1.226	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr3_+_134775404	1.226		CDV3	CDV3 homolog (mouse)
chr4_+_119419354	1.221		SNHG8	small nucleolar RNA host gene 8 (non-protein coding)
chr2_+_181554048	1.206		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr14_+_99507848	1.197		EVL	Enah/Vasp-like
chr16_+_24458349	1.168	NM_006910 NM_018703 NM_032626	RBBP6	retinoblastoma binding protein 6
chr1_+_93317374	1.165	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr9_-_126945536	1.164	NM_001144877 NM_173690	SCAI	suppressor of cancer cell invasion
chr6_-_86445138	1.151		SNHG5	small nucleolar RNA host gene 5 (non-protein coding)
chr10_+_92912676	1.144		PCGF5	polycomb group ring finger 5
chr9_+_130354490	1.137	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr20_-_32877029	1.137	NM_014071	NCOA6	nuclear receptor coactivator 6
chr15_+_65600520	1.121	NM_001143936	C15orf61	chromosome 15 open reading frame 61
chr22_+_30670543	1.115		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr1_+_176960896	1.112	NM_152663	RALGPS2	Ral GEF with PH domain and SH3 binding motif 2
chr1_-_94147537	1.089		GCLM	glutamate-cysteine ligase, modifier subunit
chr3_+_112273352	1.073		PVRL3	poliovirus receptor-related 3
chr6_-_163754903	1.068		LOC100526820	hypothetical LOC100526820
chr2_+_191222077	1.066	NM_005966	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)
chr7_+_116099648	1.061	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr20_+_36810510	1.059	NM_024855	ACTR5	ARP5 actin-related protein 5 homolog (yeast)
chr21_+_33619067	1.053	NM_000629	IFNAR1	interferon (alpha, beta and omega) receptor 1
chr10_+_105716836	1.046		SLK	STE20-like kinase
chr12_-_98902562	1.042	NM_152788	ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_94147574	1.039	NM_002061	GCLM	glutamate-cysteine ligase, modifier subunit
chr1_+_25629968	1.035	NM_018202	TMEM57	transmembrane protein 57
chr2_+_36436873	1.035	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_+_73073570	1.029	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr2_+_149118791	1.028		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr20_-_3102169	1.027		ProSAPiP1	ProSAPiP1 protein
chr18_+_9465528	1.022	NM_006788	RALBP1	ralA binding protein 1
chr6_+_157140733	1.019	NM_017519 NM_020732	ARID1B	AT rich interactive domain 1B (SWI1-like)
chr21_+_33619147	1.018		IFNAR1	interferon (alpha, beta and omega) receptor 1
chr11_+_109469296	1.013	NM_033390	ZC3H12C	zinc finger CCCH-type containing 12C
chr16_+_66153810	1.012	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr15_+_37660568	1.007	NM_003246	THBS1	thrombospondin 1
chr2_+_181553333	1.006	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr20_+_30410447	1.004		ASXL1	additional sex combs like 1 (Drosophila)
chr16_+_83291055	1.002	NM_005153	USP10	ubiquitin specific peptidase 10
chr9_+_91115924	1.000	NM_001827	CKS2	CDC28 protein kinase regulatory subunit 2
chr2_+_85619797	0.998	NM_005911	MAT2A	methionine adenosyltransferase II, alpha
chr2_+_187059277	0.994		ZC3H15	zinc finger CCCH-type containing 15
chr15_-_27650218	0.993	NM_015307	FAM189A1	family with sequence similarity 189, member A1
chr2_+_36436316	0.992		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr20_-_48980858	0.991	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr1_+_52380633	0.991	NM_004799 NM_007323 NM_007324	ZFYVE9	zinc finger, FYVE domain containing 9
chr8_+_22354712	0.988		PPP3CC	protein phosphatase 3, catalytic subunit, gamma isozyme
chr17_+_2443652	0.987	NM_000430	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr12_+_48046946	0.984	NM_023071	SPATS2	spermatogenesis associated, serine-rich 2
chr8_+_22354532	0.983	NM_005605	PPP3CC	protein phosphatase 3, catalytic subunit, gamma isozyme
chr22_+_27993997	0.983	NM_001163285 NM_001163286 NM_001163287 NM_005243 NM_013986	EWSR1	Ewing sarcoma breakpoint region 1
chr3_-_189354510	0.957		LOC339929	hypothetical LOC339929
chr10_+_105716925	0.952		SLK	STE20-like kinase
chr4_+_95592067	0.951		PDLIM5	PDZ and LIM domain 5
chr16_+_83291097	0.936		USP10	ubiquitin specific peptidase 10
chr12_+_105873669	0.928	NM_152261	C12orf23	chromosome 12 open reading frame 23
chr4_+_95592030	0.925	NM_001011513 NM_001011515 NM_001011516 NM_006457	PDLIM5	PDZ and LIM domain 5
chr20_+_5934761	0.921		CRLS1	cardiolipin synthase 1
chr8_+_26204960	0.920		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr3_+_142143329	0.916	NM_001104647 NM_018155	SLC25A36	solute carrier family 25, member 36
chr4_+_113372287	0.912	NM_001128426 NM_018569	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr12_+_15366712	0.910	NM_002848 NM_030667	PTPRO	protein tyrosine phosphatase, receptor type, O
chr2_+_28828112	0.899	NM_206876 NM_002709	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme
chr20_+_5934560	0.893	NM_019095	CRLS1	cardiolipin synthase 1
chr6_+_157140895	0.893
chr8_+_26204997	0.888		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr17_+_70964258	0.888	NM_014738	KIAA0195	KIAA0195
chr19_+_37763927	0.887	NM_004708	PDCD5	programmed cell death 5
chr1_+_160797973	0.883		UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1
chr1_+_28936030	0.878	NM_001172828	YTHDF2	YTH domain family, member 2
chr17_+_32924110	0.877		DUSP14	dual specificity phosphatase 14
chr12_+_92295738	0.874	NM_019094 NM_199040	NUDT4 NUDT4P1	nudix (nucleoside diphosphate linked moiety X)-type motif 4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr13_+_34414390	0.867	NM_015678	NBEA	neurobeachin
chr20_+_56899904	0.867		GNAS	GNAS complex locus
chr2_-_203444468	0.863	NM_138468	ICA1L	islet cell autoantigen 1,69kDa-like
chr2_+_200484251	0.863		C2orf69	chromosome 2 open reading frame 69
chr1_-_92537087	0.855	NM_053274	GLMN	glomulin, FKBP associated protein
chr13_-_109236897	0.850	NM_003749	IRS2	insulin receptor substrate 2
chr4_+_57469122	0.837		REST	RE1-silencing transcription factor
chr21_+_34367678	0.837	NM_032476 NM_006933	MRPS6 SLC5A3	mitochondrial ribosomal protein S6 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr2_+_54536780	0.833	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr1_+_92537109	0.833	NM_024813	RPAP2	RNA polymerase II associated protein 2
chr4_+_57468847	0.833		REST	RE1-silencing transcription factor
chr2_+_200484270	0.829		C2orf69	chromosome 2 open reading frame 69
chr5_+_14196287	0.828	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr15_+_83092854	0.819		ZNF592	zinc finger protein 592
chr8_+_87424074	0.812	NM_007013	WWP1	WW domain containing E3 ubiquitin protein ligase 1
chr3_+_189354167	0.809	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr18_-_72336133	0.807	NM_014643	ZNF516	zinc finger protein 516
chr13_-_105985313	0.806	NM_004093	EFNB2	ephrin-B2
chr10_+_92970302	0.805	NM_032373	PCGF5	polycomb group ring finger 5
chr2_-_200424140	0.801		LOC348751	hypothetical LOC348751
chr13_+_51056648	0.800		WDFY2	WD repeat and FYVE domain containing 2
chr16_+_83291112	0.799		USP10	ubiquitin specific peptidase 10
chr15_+_38013559	0.795	NM_001013703	EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4
chr3_+_184898234	0.794	NM_018023	YEATS2	YEATS domain containing 2
chr2_+_170298700	0.793		KLHL23	kelch-like 23 (Drosophila)
chr2_+_9264360	0.792		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr7_+_26208532	0.782
chr6_-_13922525	0.780	NM_001031713	CCDC90A	coiled-coil domain containing 90A
chr12_-_37585602	0.778	NM_153634	CPNE8	copine VIII
chr12_+_109203412	0.778	NM_001135765 NM_001681 NM_170665	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr1_+_213807321	0.770	NM_016121	KCTD3	potassium channel tetramerisation domain containing 3
chr17_+_32924049	0.769	NM_007026	DUSP14	dual specificity phosphatase 14
chr7_-_80386602	0.767	NM_006379	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_75039273	0.767	NM_019896	POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr7_-_80386258	0.761		SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_149895274	0.758	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr1_+_36046373	0.757	NM_017629	EIF2C4	eukaryotic translation initiation factor 2C, 4
chr8_+_87595762	0.754	NM_003909	CPNE3	copine III
chr17_+_2443983	0.751		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr9_+_130491340	0.751		SET	SET nuclear oncogene
chr13_+_75021886	0.747	NM_006002	UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr4_+_140594410	0.746	NM_031296	RAB33B	RAB33B, member RAS oncogene family
chr12_+_95112385	0.746		ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr2_+_28971007	0.741	NM_015131	WDR43	WD repeat domain 43
chr20_+_56899867	0.740		GNAS	GNAS complex locus
chr2_+_46779553	0.737	NM_014011	SOCS5	suppressor of cytokine signaling 5
chr12_+_6907646	0.736	NM_001940	ATN1	atrophin 1
chr16_+_30617962	0.736	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr4_+_99401543	0.736	NM_001100426 NM_001100427 NM_001100428 NM_001100429 NM_001100430 NM_021159	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1
chr13_-_50315832	0.733	NM_198989	DLEU7	deleted in lymphocytic leukemia, 7
chr9_+_90193058	0.729	NM_006717	SPIN1	spindlin 1
chr8_+_87595782	0.719		CPNE3	copine III
chr8_+_28407613	0.715	NM_017412	FZD3	frizzled homolog 3 (Drosophila)
chr11_+_105453501	0.708	NM_015423	AASDHPPT	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr1_-_58815753	0.707	NM_002353	TACSTD2	tumor-associated calcium signal transducer 2
chr12_+_75682016	0.706		ZDHHC17	zinc finger, DHHC-type containing 17
chr12_+_95112131	0.703	NM_005230	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr8_+_22354276	0.701		PPP3CC	protein phosphatase 3, catalytic subunit, gamma isozyme
chr2_+_9264327	0.697	NM_001135191 NM_003887	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr3_+_129253977	0.693		SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)
chr4_+_113286001	0.692	NM_152400	C4orf32	chromosome 4 open reading frame 32
chr4_-_110574363	0.689		1/2-SBSRNA4	lncRNA_BC009800
chr6_+_111911226	0.686		LOC643749	hypothetical LOC643749
chr15_-_29950188	0.679		OTUD7A	OTU domain containing 7A
chr13_-_40533072	0.678		ELF1	E74-like factor 1 (ets domain transcription factor)
chr2_+_206732859	0.677		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr3_+_73128629	0.675		PPP4R2	protein phosphatase 4, regulatory subunit 2
chr12_+_75681973	0.670	NM_015336	ZDHHC17	zinc finger, DHHC-type containing 17
chr13_+_97593711	0.669		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_+_32069183	0.666		RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr17_+_11864841	0.662	NM_003010	MAP2K4	mitogen-activated protein kinase kinase 4
chr3_+_185563872	0.661	NM_006232	POLR2H	polymerase (RNA) II (DNA directed) polypeptide H
chr1_-_62926533	0.659	NM_033407	DOCK7	dedicator of cytokinesis 7
chr16_+_56038837	0.658	NM_020312	COQ9	coenzyme Q9 homolog (S. cerevisiae)
chr16_+_83291107	0.658		USP10	ubiquitin specific peptidase 10
chr14_-_24588916	0.657	NM_014178	STXBP6	syntaxin binding protein 6 (amisyn)
chr17_+_57909979	0.656	NM_001112707 NM_006852	TLK2	tousled-like kinase 2
chr3_+_129253997	0.655		SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)
chr15_+_56850776	0.654		FAM63B	family with sequence similarity 63, member B
chr16_+_15397120	0.653		MPV17L	MPV17 mitochondrial membrane protein-like
chr3_+_134775247	0.650		CDV3	CDV3 homolog (mouse)
chr18_+_58341637	0.647	NM_017742	ZCCHC2	zinc finger, CCHC domain containing 2
chr10_-_104463947	0.646	NM_004311	ARL3	ADP-ribosylation factor-like 3
chr8_+_94998258	0.641	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_+_8660913	0.635		RPL27A	ribosomal protein L27a
chr16_+_55523248	0.635	NM_001010989 NM_001010990 NM_014685	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr1_-_227828416	0.633	NM_001025247 NM_014409	TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr2_+_138975819	0.633	NM_001001664	SPOPL	speckle-type POZ protein-like
chr20_+_6696744	0.631	NM_001200	BMP2	bone morphogenetic protein 2
chr3_+_73128667	0.631		PPP4R2	protein phosphatase 4, regulatory subunit 2
chr10_+_92970487	0.630		PCGF5	polycomb group ring finger 5
chr2_+_97142959	0.629	NM_001164315	ANKRD36	ankyrin repeat domain 36

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.24	1.13e-17	GO:0044237	cellular metabolic process
1.29	7.35e-15	GO:0044260	cellular macromolecule metabolic process
1.21	4.63e-14	GO:0044238	primary metabolic process
1.19	1.24e-13	GO:0008152	metabolic process
1.11	4.19e-11	GO:0009987	cellular process
1.23	5.15e-11	GO:0043170	macromolecule metabolic process
1.42	3.50e-10	GO:0006464	protein modification process
1.35	5.31e-10	GO:0044267	cellular protein metabolic process
1.38	1.11e-08	GO:0043412	macromolecule modification
1.93	3.12e-08	GO:0016568	chromatin modification
1.40	1.05e-07	GO:0006996	organelle organization
1.29	2.95e-07	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76	3.96e-07	GO:0006325	chromatin organization
1.29	5.13e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.25	7.13e-07	GO:0006807	nitrogen compound metabolic process
1.26	9.82e-07	GO:0034641	cellular nitrogen compound metabolic process
1.26	2.07e-06	GO:0019538	protein metabolic process
1.63	2.75e-06	GO:0051276	chromosome organization
1.28	2.90e-06	GO:0071842	cellular component organization at cellular level
1.23	1.14e-05	GO:0071840	cellular component organization or biogenesis
1.22	3.87e-05	GO:0016043	cellular component organization
1.26	4.34e-05	GO:0009058	biosynthetic process
1.26	8.85e-05	GO:0044249	cellular biosynthetic process
1.80	5.48e-04	GO:0032446	protein modification by small protein conjugation
1.96	1.43e-03	GO:0016569	covalent chromatin modification
1.96	1.91e-03	GO:0016570	histone modification
1.78	2.91e-03	GO:0016567	protein ubiquitination
1.24	3.24e-03	GO:0090304	nucleic acid metabolic process
1.47	4.36e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.66	6.65e-03	GO:0070647	protein modification by small protein conjugation or removal
1.62	1.49e-02	GO:0018193	peptidyl-amino acid modification
1.26	2.29e-02	GO:0009059	macromolecule biosynthetic process
1.34	2.63e-02	GO:0006793	phosphorus metabolic process
1.34	2.63e-02	GO:0006796	phosphate metabolic process
1.32	2.82e-02	GO:0044248	cellular catabolic process
2.35	2.98e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.26	3.00e-02	GO:0034645	cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.18	2.34e-41	GO:0005622	intracellular
1.18	3.46e-40	GO:0044424	intracellular part
1.22	6.65e-27	GO:0005737	cytoplasm
1.17	5.64e-24	GO:0043226	organelle
1.17	7.27e-24	GO:0043229	intracellular organelle
1.19	4.89e-22	GO:0043231	intracellular membrane-bounded organelle
1.19	5.85e-22	GO:0043227	membrane-bounded organelle
1.23	4.62e-16	GO:0044444	cytoplasmic part
1.23	9.36e-14	GO:0005634	nucleus
1.40	1.12e-11	GO:0005829	cytosol
1.21	3.00e-11	GO:0044446	intracellular organelle part
1.20	1.30e-10	GO:0044422	organelle part
1.32	9.23e-08	GO:0044428	nuclear part
1.28	1.87e-06	GO:0031974	membrane-enclosed lumen
1.29	2.22e-06	GO:0070013	intracellular organelle lumen
1.28	3.62e-06	GO:0043233	organelle lumen
1.31	6.50e-06	GO:0031981	nuclear lumen
1.04	1.32e-05	GO:0044464	cell part
1.04	1.39e-05	GO:0005623	cell
1.22	1.64e-04	GO:0043228	non-membrane-bounded organelle
1.22	1.64e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.18	5.65e-04	GO:0032991	macromolecular complex
1.30	1.94e-03	GO:0005739	mitochondrion
1.26	4.09e-03	GO:0012505	endomembrane system
1.73	5.52e-03	GO:0005813	centrosome
1.29	5.58e-03	GO:0005654	nucleoplasm
1.21	1.04e-02	GO:0031090	organelle membrane
1.78	1.30e-02	GO:0031252	cell leading edge
1.84	1.37e-02	GO:0031300	intrinsic to organelle membrane
1.17	1.42e-02	GO:0043234	protein complex
1.55	1.62e-02	GO:0005815	microtubule organizing center
1.45	1.72e-02	GO:0005730	nucleolus
1.85	3.73e-02	GO:0031301	integral to organelle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	9.61e-14	GO:0005515	protein binding
1.10	2.11e-12	GO:0005488	binding
1.21	2.07e-10	GO:0003824	catalytic activity
1.53	2.35e-06	GO:0019899	enzyme binding
1.28	5.46e-06	GO:0000166	nucleotide binding
1.67	6.20e-06	GO:0016874	ligase activity
1.32	7.58e-06	GO:0016740	transferase activity
1.29	5.81e-05	GO:0032553	ribonucleotide binding
1.29	5.81e-05	GO:0032555	purine ribonucleotide binding
1.28	7.61e-05	GO:0017076	purine nucleotide binding
1.29	7.95e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.77	9.22e-05	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.31	2.78e-04	GO:0032559	adenyl ribonucleotide binding
1.30	3.25e-04	GO:0030554	adenyl nucleotide binding
1.30	4.13e-04	GO:0005524	ATP binding
1.75	7.93e-04	GO:0016881	acid-amino acid ligase activity
1.37	2.75e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.18	2.79e-03	GO:0003676	nucleic acid binding
1.74	4.24e-03	GO:0019787	small conjugating protein ligase activity
1.76	5.14e-03	GO:0004842	ubiquitin-protein ligase activity
1.87	7.01e-03	GO:0000287	magnesium ion binding
1.69	1.07e-02	GO:0016791	phosphatase activity
1.14	4.33e-02	GO:0043169	cation binding
1.14	4.55e-02	GO:0046872	metal ion binding
1.14	4.78e-02	GO:0043167	ion binding