Motif ID: SPI1.p2

Z-value: 1.391


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473566720.146.0e-01Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_42947754 1.392 NM_003404
NM_139323
 YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr20_+_42947764 1.342 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr15_+_36332258 0.988 NM_152594
 SPRED1
sprouty-related, EVH1 domain containing 1
chr11_+_61352348 0.964 FADS2
fatty acid desaturase 2
chr3_-_107070400 0.952 NM_170662
 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr17_+_24742068 0.947 NM_020791
 TAOK1
TAO kinase 1
chr3_+_189354167 0.928 NM_001167672
 LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_88190737 0.902 NM_001008390
NM_003663
 CGGBP1

CGG triplet repeat binding protein 1

chr1_+_67168470 0.881 NM_001077701
NM_001077704
 MIER1

mesoderm induction early response 1 homolog (Xenopus laevis)

chr2_+_46779827 0.814 NM_144949
 SOCS5
suppressor of cytokine signaling 5
chr2_+_85051687 0.777 NM_020122
 KCMF1
potassium channel modulatory factor 1
chr14_+_85069217 0.758


chr8_+_104582151 0.747 NM_001100117
 RIMS2
regulating synaptic membrane exocytosis 2
chr11_+_61352209 0.744 NM_004265
 FADS2
fatty acid desaturase 2
chr17_+_4683280 0.741 NM_001024937
NM_015716
NM_153827
NM_170663
 MINK1



misshapen-like kinase 1



chr6_+_87921980 0.725 NM_015021
 ZNF292
zinc finger protein 292
chr3_+_108724472 0.718 NM_001142568
NM_020235
 BBX

bobby sox homolog (Drosophila)

chr14_-_47213906 0.703 NM_001113498
 MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr3_+_132095496 0.696 ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr2_+_46779553 0.687 NM_014011
 SOCS5
suppressor of cytokine signaling 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
1.51 2.48e-04 GO:0032446 protein modification by small protein conjugation
1.49 2.01e-03 GO:0016567 protein ubiquitination
1.45 1.00e-03 GO:0070647 protein modification by small protein conjugation or removal
1.38 3.19e-04 GO:0001775 cell activation
1.38 2.76e-02 GO:0044257 cellular protein catabolic process
1.38 4.22e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.32 1.07e-02 GO:0044265 cellular macromolecule catabolic process
1.32 2.51e-02 GO:0007596 blood coagulation
1.32 2.51e-02 GO:0050817 coagulation
1.32 2.60e-02 GO:0007599 hemostasis
1.31 2.11e-02 GO:0016071 mRNA metabolic process
1.30 8.68e-03 GO:0009057 macromolecule catabolic process
1.21 1.16e-02 GO:0031325 positive regulation of cellular metabolic process
1.21 2.47e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.20 7.54e-05 GO:0006464 protein modification process
1.20 2.48e-02 GO:0009893 positive regulation of metabolic process
1.19 2.12e-06 GO:0044267 cellular protein metabolic process
1.19 2.12e-02 GO:0009966 regulation of signal transduction
1.18 8.20e-04 GO:0043412 macromolecule modification
1.17 4.72e-02 GO:0023051 regulation of signaling

Gene overrepresentation in compartment category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
1.55 4.15e-02 GO:0016607 nuclear speck
1.30 7.69e-05 GO:0044451 nucleoplasm part
1.24 8.88e-06 GO:0005654 nucleoplasm
1.20 3.96e-07 GO:0044428 nuclear part
1.20 7.28e-06 GO:0031981 nuclear lumen
1.17 9.44e-06 GO:0043233 organelle lumen
1.17 1.52e-05 GO:0031974 membrane-enclosed lumen
1.17 4.98e-05 GO:0005829 cytosol
1.16 4.70e-07 GO:0043234 protein complex
1.16 1.81e-04 GO:0070013 intracellular organelle lumen
1.14 1.38e-06 GO:0032991 macromolecular complex
1.11 3.99e-07 GO:0005634 nucleus
1.09 3.68e-04 GO:0044446 intracellular organelle part
1.09 4.39e-04 GO:0044422 organelle part
1.07 5.25e-05 GO:0005737 cytoplasm
1.06 5.16e-10 GO:0005622 intracellular
1.06 1.05e-09 GO:0044424 intracellular part
1.06 3.23e-04 GO:0043226 organelle
1.06 8.32e-04 GO:0043227 membrane-bounded organelle
1.06 1.19e-03 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.70 2.95e-02 GO:0035257 nuclear hormone receptor binding
1.69 1.14e-02 GO:0051427 hormone receptor binding
1.47 3.92e-03 GO:0019787 small conjugating protein ligase activity
1.46 7.68e-03 GO:0004842 ubiquitin-protein ligase activity
1.41 1.36e-02 GO:0016881 acid-amino acid ligase activity
1.31 1.49e-02 GO:0016874 ligase activity
1.31 2.98e-02 GO:0019904 protein domain specific binding
1.24 1.66e-02 GO:0019899 enzyme binding
1.12 8.81e-14 GO:0005515 protein binding
1.06 2.24e-08 GO:0005488 binding