Motif ID: HOXA9_MEIS1.p2

Z-value: 0.693


Transcription factors associated with HOXA9_MEIS1.p2:

Gene SymbolEntrez IDGene Name
HOXA9 3205 homeobox A9
MEIS1 4211 Meis homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEIS1chr2_+_665199490.263.3e-01Click!
HOXA9chr7_-_27171673-0.097.3e-01Click!


Activity profile for motif HOXA9_MEIS1.p2.

activity profile for motif HOXA9_MEIS1.p2


Sorted Z-values histogram for motif HOXA9_MEIS1.p2

Sorted Z-values for motif HOXA9_MEIS1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA9_MEIS1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_102870207 0.888 NM_001024452
NM_001172285
GLRA4

glycine receptor, alpha 4

chrX_-_105169370 0.872 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_+_115650240 0.737 NM_152829
TES
testis derived transcript (3 LIM domains)
chr15_+_64481270 0.681 MAP2K1
mitogen-activated protein kinase kinase 1
chr12_+_7348194 0.663 NM_001080454
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr4_+_123311207 0.655 NM_015312
KIAA1109
KIAA1109
chr1_-_611896 0.619 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr21_+_30724442 0.548 NM_181600
KRTAP13-4
keratin associated protein 13-4
chr18_+_2645885 0.496 NM_015295
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr10_-_76488277 0.481 NM_001003892
DUPD1
dual specificity phosphatase and pro isomerase domain containing 1
chr18_-_29882555 0.459 NM_001198549
NOL4
nucleolar protein 4
chr2_+_204440753 0.450 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr15_-_23204887 0.435 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr1_-_154041393 0.434 GON4L
gon-4-like (C. elegans)
chrX_-_131181141 0.431 RAP2C
RAP2C, member of RAS oncogene family
chrX_+_135106578 0.412 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chrX_-_130792297 0.387 LOC286467
hypothetical LOC286467
chr3_-_191650291 0.386 NM_207316
TMEM207
transmembrane protein 207
chr6_-_29451042 0.381 NM_030959
OR12D3
olfactory receptor, family 12, subfamily D, member 3
chr1_+_115373937 0.368 NM_000549
TSHB
thyroid stimulating hormone, beta
chrX_+_37750778 0.356 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr17_+_53587492 0.344 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr11_+_27019084 0.343 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr6_-_52217185 0.337 NM_052872
IL17F
interleukin 17F
chrX_-_83644054 0.304 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr7_+_104468614 0.290 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chrX_-_43717864 0.285 NM_000266
NDP
Norrie disease (pseudoglioma)
chr10_+_32896656 0.276 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr4_-_166253453 0.274 NM_001100389
TMEM192
transmembrane protein 192
chr2_+_114916368 0.264 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr21_-_46849413 0.263 NM_006272
S100B
S100 calcium binding protein B
chr12_-_51332214 0.261 NM_000423
KRT2
keratin 2
chrX_-_71709335 0.238 HDAC8
histone deacetylase 8
chr11_+_55297489 0.237 NM_001001967
OR5D13
olfactory receptor, family 5, subfamily D, member 13
chrX_-_137777382 0.237 NM_001139502
FGF13
fibroblast growth factor 13
chr3_-_173723754 0.226 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr12_+_11694172 0.219 ETV6
ets variant 6
chr3_-_115380539 0.216 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr12_+_53809731 0.215 NM_001005243
OR9K2
olfactory receptor, family 9, subfamily K, member 2
chrX_+_100361588 0.210 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr8_-_17599438 0.209 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr10_-_46039941 0.207 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr7_+_143457083 0.202 NM_001001659
OR2A14
olfactory receptor, family 2, subfamily A, member 14
chr15_+_42815851 0.198 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chrX_-_129099695 0.196 NM_001130846
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr16_-_52877868 0.194 NM_024336
IRX3
iroquois homeobox 3
chr1_-_167865973 0.187 NM_003005
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr4_-_122357104 0.187 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr19_+_61624 0.187 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr3_-_27473248 0.187 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr9_-_72926333 0.184 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr4_-_166253374 0.181 TMEM192
transmembrane protein 192
chr7_-_143560850 0.180 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr1_+_58899 0.177 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr19_-_15451203 0.167 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr11_+_48284350 0.166 NM_001004725
OR4S1
olfactory receptor, family 4, subfamily S, member 1
chr7_+_143646150 0.165 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr19_+_9222605 0.164 NM_001079935
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chrX_+_123062143 0.159 STAG2
stromal antigen 2
chr5_+_140780720 0.156 NM_018914
NM_032091
NM_032092
PCDHGA11


protocadherin gamma subfamily A, 11


chr15_+_36776090 0.151 NM_207444
C15orf53
chromosome 15 open reading frame 53
chr1_+_227506751 0.143 NM_006542
SPHAR
S-phase response (cyclin related)
chr1_+_357502 0.143 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr4_-_87247829 0.141 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr3_-_188903038 0.140 NM_001004312
RTP2
receptor (chemosensory) transporter protein 2
chr8_+_76614757 0.140 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr3_+_14691609 0.139 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr5_+_128328685 0.139 SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr6_+_29382381 0.135 NM_030946
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr1_+_144374513 0.134 RNF115
ring finger protein 115
chrX_-_106033202 0.134 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr9_-_99001551 0.132 NM_199005
ZNF322B
ZNF322A
zinc finger protein 322B
zinc finger protein 322A
chr11_-_7804094 0.129 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr2_-_225078931 0.126 CUL3
cullin 3
chr17_+_41728273 0.125 NM_014834
LRRC37A
leucine rich repeat containing 37A
chr16_-_24850163 0.124 ARHGAP17
Rho GTPase activating protein 17
chr8_-_13018123 0.124 NM_001164271
DLC1
deleted in liver cancer 1
chr13_+_78068246 0.124 LOC780529
hypothetical LOC780529
chr17_+_17548888 0.123


chr14_+_19285426 0.123 NM_172194
OR4Q3
olfactory receptor, family 4, subfamily Q, member 3
chr3_+_58459131 0.123 NM_153331
KCTD6
potassium channel tetramerisation domain containing 6
chr10_+_98730977 0.122 NM_015652
C10orf12
chromosome 10 open reading frame 12
chr11_+_68124400 0.122 PPP6R3
protein phosphatase 6, regulatory subunit 3
chr14_+_19473606 0.122 NM_001004063
OR4K1
olfactory receptor, family 4, subfamily K, member 1
chr5_-_160044844 0.121 ATP10B
ATPase, class V, type 10B
chr22_+_23921072 0.121 KIAA1671
KIAA1671
chr3_-_150952944 0.120 NM_016094
COMMD2
COMM domain containing 2
chr11_-_104515670 0.120 NM_021571
CARD18
caspase recruitment domain family, member 18
chr11_-_5964790 0.119 NM_001005173
OR52L1
olfactory receptor, family 52, subfamily L, member 1
chrX_+_117410693 0.116 WDR44
WD repeat domain 44
chr11_-_62145952 0.113 NM_012200
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr15_+_55298908 0.111 NM_207040
TCF12
transcription factor 12
chr3_+_99484421 0.104 NM_001005482
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr1_-_167822248 0.104 F5
coagulation factor V (proaccelerin, labile factor)
chrX_-_77469635 0.103 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr1_+_245818284 0.101 NM_001001915
OR2G2
olfactory receptor, family 2, subfamily G, member 2
chr9_+_124463665 0.100 NM_001005236
OR1L1
olfactory receptor, family 1, subfamily L, member 1
chr18_+_53967544 0.098 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr9_-_21197141 0.096 NM_002171
IFNA10
interferon, alpha 10
chr7_-_107230867 0.096 NM_000111
SLC26A3
solute carrier family 26, member 3
chr7_+_90177082 0.095 CDK14
cyclin-dependent kinase 14
chrX_-_110541029 0.095 NM_000555
DCX
doublecortin
chr12_-_16649211 0.094 LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_+_143287952 0.093 NM_012369
OR2F1
olfactory receptor, family 2, subfamily F, member 1
chr3_-_174341653 0.092 NM_031955
SPATA16
spermatogenesis associated 16
chr2_-_43756964 0.092 NM_001101330
LOC728819
hCG1645220
chr8_+_133856738 0.091 NM_016018
NM_032205
NM_198513
PHF20L1


PHD finger protein 20-like 1


chr3_+_82117978 0.090


chr6_+_73133152 0.089 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr3_-_150952920 0.089 COMMD2
COMM domain containing 2
chr4_-_120445047 0.088 NM_001170330
C4orf3
chromosome 4 open reading frame 3
chr3_-_56477404 0.088 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr3_-_69120188 0.087 C3orf64
chromosome 3 open reading frame 64
chr1_+_57093030 0.086 NM_000562
C8A
complement component 8, alpha polypeptide
chr1_+_151498802 0.085 NM_000427
LOR
loricrin
chr15_-_74091817 0.085 NM_138573
NRG4
neuregulin 4
chr11_+_71524403 0.085 NM_000804
FOLR3
folate receptor 3 (gamma)
chr7_-_50596238 0.085 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr5_+_180726874 0.084 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr3_+_150028130 0.084 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr15_+_46285789 0.084 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr11_-_4675524 0.084 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr18_-_49944986 0.082 MBD2
methyl-CpG binding domain protein 2
chr2_-_210726539 0.082 C2orf67
chromosome 2 open reading frame 67
chr8_+_17874128 0.081 PCM1
pericentriolar material 1
chr3_-_121117647 0.081 GSK3B
glycogen synthase kinase 3 beta
chr1_-_196776697 0.081 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr11_-_5946299 0.080 NM_001146033
OR56A5
olfactory receptor, family 56, subfamily A, member 5
chr1_+_67404756 0.080 NM_144701
IL23R
interleukin 23 receptor
chr1_-_245237925 0.079 ZNF695
zinc finger protein 695
chr1_-_245237977 0.079 NM_020394
ZNF695
zinc finger protein 695
chr13_-_102209422 0.077 NM_001146197
C13orf40
chromosome 13 open reading frame 40
chr16_-_71639670 0.075 NM_006885
ZFHX3
zinc finger homeobox 3
chrX_+_48221323 0.075 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr12_+_84792203 0.072 NM_006183
NTS
neurotensin
chr6_+_28032997 0.071 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr3_+_157321030 0.070 NM_172160
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr5_-_58607673 0.070 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_42590038 0.069 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr4_-_153523113 0.068 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr12_-_10453409 0.067 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr21_-_36760594 0.066 NM_012130
CLDN14
claudin 14
chr7_+_63411813 0.064 ZNF736
zinc finger protein 736
chr14_+_67238355 0.064 NM_152443
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr1_-_176273680 0.064 LOC730102
quinone oxidoreductase-like protein 2 pseudogene
chr6_-_11219932 0.064 NM_207582
ERVFRDE1
HERV-FRD provirus ancestral Env polyprotein
chr4_+_146820805 0.064 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr6_+_35308605 0.064 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr21_+_30910614 0.064 NM_181615
KRTAP20-1
keratin associated protein 20-1
chr12_+_61645361 0.063 RPL14
ribosomal protein L14
chr1_+_169747788 0.063 PRRC2C
proline-rich coiled-coil 2C
chr17_-_36403910 0.062 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr9_+_4782974 0.062 RCL1
RNA terminal phosphate cyclase-like 1
chr21_-_31175722 0.061 NM_175858
KRTAP11-1
keratin associated protein 11-1
chr12_-_49708279 0.060 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr9_+_92629525 0.060 NM_001174167
SYK
spleen tyrosine kinase
chr10_+_129237602 0.059 NM_001030013
NPS
neuropeptide S
chr12_-_45506001 0.059 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr9_-_21375258 0.058 NM_000605
IFNA2
interferon, alpha 2
chr19_+_44681443 0.058 DLL3
delta-like 3 (Drosophila)
chr8_-_38577891 0.058


chr11_-_3104413 0.057 OSBPL5
oxysterol binding protein-like 5
chr3_+_174598937 0.057 NM_014932
NLGN1
neuroligin 1
chr3_+_112743729 0.056 CD96
CD96 molecule
chr20_+_19818209 0.056 NM_018993
RIN2
Ras and Rab interactor 2
chr7_+_44612645 0.056 NM_001003941
NM_001165036
NM_002541
OGDH


oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)


chr1_+_13903936 0.056 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr20_+_33223434 0.055 NM_006404
PROCR
protein C receptor, endothelial
chr12_+_76749199 0.054 NM_014903
NAV3
neuron navigator 3
chr3_+_153014550 0.054 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr5_+_140583098 0.053 NM_018934
PCDHB14
protocadherin beta 14
chr11_-_47502115 0.053 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr1_-_153477511 0.052 GBA
glucosidase, beta, acid
chr5_-_179040580 0.052 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chr12_-_119249938 0.051 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr8_+_133856793 0.051 PHF20L1
PHD finger protein 20-like 1
chr5_+_140730014 0.051 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr22_+_29696662 0.051


chr9_-_14076901 0.051 NFIB
nuclear factor I/B
chr4_+_68995761 0.050 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr1_-_156056456 0.050 NM_001159397
NM_001159398
NM_052938
FCRL1


Fc receptor-like 1


chr10_+_89409332 0.050 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr3_+_112743615 0.050 NM_005816
NM_198196
CD96

CD96 molecule

chr7_+_91762227 0.049


chr4_-_40631397 0.048 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr12_-_119826433 0.048 NM_139015
SPPL3
signal peptide peptidase 3
chr19_-_43926953 0.048 NM_144691
CAPN12
calpain 12
chr12_-_85756766 0.047 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr20_-_44575599 0.047 NM_018102
NM_199441
ZNF334

zinc finger protein 334

chr6_+_25760352 0.047 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr3_-_126576693 0.046 NM_021964
ZNF148
zinc finger protein 148
chr14_+_19598043 0.045 NM_001004717
OR4L1
olfactory receptor, family 4, subfamily L, member 1
chrX_+_27736027 0.045 NM_182506
MAGEB10
melanoma antigen family B, 10
chr3_-_194579207 0.045 NM_198505
ATP13A5
ATPase type 13A5
chr12_-_44670584 0.044 SCAF11
SR-related CTD-associated factor 11
chr1_-_84099261 0.044


chr3_+_123279439 0.044 NM_006889
CD86
CD86 molecule
chr3_-_87408301 0.044 NM_000306
NM_001122757
POU1F1

POU class 1 homeobox 1

chr8_-_42817604 0.043 NM_018105
NM_199003
THAP1

THAP domain containing, apoptosis associated protein 1

chr12_-_66905802 0.043 NM_018402
IL26
interleukin 26

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.91 7.47e-11 GO:0007608 sensory perception of smell
4.39 1.55e-09 GO:0007606 sensory perception of chemical stimulus
3.00 9.55e-07 GO:0007600 sensory perception
2.17 1.37e-05 GO:0003008 system process
2.28 6.30e-05 GO:0050877 neurological system process
2.44 1.05e-02 GO:0006955 immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.53 3.00e-04 GO:0005886 plasma membrane
1.50 5.84e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.31 8.10e-13 GO:0004984 olfactory receptor activity
3.05 5.43e-08 GO:0004930 G-protein coupled receptor activity
2.16 3.23e-06 GO:0004872 receptor activity
2.27 3.65e-05 GO:0004888 transmembrane receptor activity
1.89 1.10e-04 GO:0004871 signal transducer activity
1.89 1.10e-04 GO:0060089 molecular transducer activity