Motif ID: TBP.p2

Z-value: 3.098


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_170705345-0.312.4e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_6226838 5.034 NM_001024598
HES3
hairy and enhancer of split 3 (Drosophila)
chrX_+_153339814 4.082 NM_017514
PLXNA3
plexin A3
chr19_+_2220526 3.669 OAZ1
ornithine decarboxylase antizyme 1
chr1_+_151596953 3.651 NM_002965
S100A9
S100 calcium binding protein A9
chr19_+_2220515 3.515 NM_004152
OAZ1
SPPL2B
ornithine decarboxylase antizyme 1
signal peptide peptidase-like 2B
chr19_+_2220529 3.496 OAZ1
ornithine decarboxylase antizyme 1
chr22_+_38246509 3.281 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr8_-_143692814 3.273 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr3_+_195336631 3.106 HES1
hairy and enhancer of split 1, (Drosophila)
chr17_-_45901173 3.038 NM_001267
CHAD
chondroadherin
chr11_-_2138984 3.036 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough transcript
chr1_+_148090804 3.012 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr1_+_148089251 2.992 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr9_+_91409746 2.980 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chrX_+_152699616 2.921 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr9_+_139255559 2.886 TUBB2C
tubulin, beta 2C
chr3_+_195336625 2.872 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr11_+_43920385 2.859 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr11_-_2907169 2.849 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr1_+_12839527 2.833 NM_023014
PRAMEF2
PRAME family member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 66 entries
enrichment   p-value GO term description
14.60 1.74e-02 GO:0046689 response to mercury ion
12.98 9.32e-05 GO:0042744 hydrogen peroxide catabolic process
12.17 3.98e-06 GO:0042743 hydrogen peroxide metabolic process
10.43 2.36e-05 GO:0070301 cellular response to hydrogen peroxide
8.76 7.89e-06 GO:0072593 reactive oxygen species metabolic process
8.35 1.47e-05 GO:0034614 cellular response to reactive oxygen species
7.86 3.29e-02 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
7.22 5.75e-11 GO:0006334 nucleosome assembly
7.09 6.93e-12 GO:0034728 nucleosome organization
6.95 1.74e-03 GO:0031424 keratinization
6.86 1.93e-10 GO:0031497 chromatin assembly
6.33 1.33e-04 GO:0034599 cellular response to oxidative stress
6.28 1.42e-09 GO:0065004 protein-DNA complex assembly
6.20 5.94e-10 GO:0071824 protein-DNA complex subunit organization
5.95 2.63e-03 GO:0051591 response to cAMP
5.84 3.62e-04 GO:0042542 response to hydrogen peroxide
5.48 1.03e-08 GO:0006323 DNA packaging
5.12 4.67e-08 GO:0006333 chromatin assembly or disassembly
4.92 4.48e-04 GO:0000302 response to reactive oxygen species
4.90 4.77e-08 GO:0071103 DNA conformation change

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
10.83 3.10e-16 GO:0000786 nucleosome
10.59 1.97e-20 GO:0045095 keratin filament
9.74 4.46e-03 GO:0032982 myosin filament
7.35 6.35e-23 GO:0005882 intermediate filament
6.93 1.96e-11 GO:0032993 protein-DNA complex
6.36 2.83e-20 GO:0045111 intermediate filament cytoskeleton
3.49 2.35e-24 GO:0005615 extracellular space
3.39 4.71e-06 GO:0000785 chromatin
3.08 7.88e-24 GO:0044421 extracellular region part
2.89 3.67e-03 GO:0030141 stored secretory granule
2.38 3.14e-25 GO:0005576 extracellular region
1.89 5.53e-05 GO:0044430 cytoskeletal part
1.63 6.54e-04 GO:0005856 cytoskeleton
1.48 1.23e-04 GO:0043228 non-membrane-bounded organelle
1.48 1.23e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.34 2.82e-03 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
29.20 1.58e-05 GO:0046870 cadmium ion binding
29.20 1.44e-02 GO:0005549 odorant binding
14.60 3.01e-02 GO:0015250 water channel activity
10.43 2.47e-02 GO:0050664 oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor
7.38 5.04e-13 GO:0005179 hormone activity
6.18 3.51e-04 GO:0005507 copper ion binding
6.01 4.24e-02 GO:0004601 peroxidase activity
6.01 4.24e-02 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor
5.72 6.84e-03 GO:0008009 chemokine activity
5.16 1.63e-02 GO:0016209 antioxidant activity
5.16 1.63e-02 GO:0042379 chemokine receptor binding
4.11 4.54e-08 GO:0005125 cytokine activity
3.95 1.07e-06 GO:0005126 cytokine receptor binding
3.17 3.65e-14 GO:0005198 structural molecule activity
3.12 9.19e-03 GO:0008083 growth factor activity
2.89 2.51e-02 GO:0001664 G-protein-coupled receptor binding
2.37 7.43e-11 GO:0005102 receptor binding
1.18 6.53e-03 GO:0005515 protein binding