Motif ID: KLF4.p3

Z-value: 1.595


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF4chr9_-_1092905280.233.9e-01Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_129962292 3.660 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr12_+_110328126 3.306 NM_005475
SH2B3
SH2B adaptor protein 3
chr1_+_32992131 3.191


chr9_+_132961723 2.549 AIF1L
allograft inflammatory factor 1-like
chr22_+_21817512 2.354 NM_004914
RAB36
RAB36, member RAS oncogene family
chr22_+_21742727 2.296 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr1_-_1840564 2.171 NM_178545
TMEM52
transmembrane protein 52
chr7_-_158073121 2.045 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr21_+_44699796 2.025 NM_030891
LRRC3
leucine rich repeat containing 3
chr22_-_17546296 1.852 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_+_21742364 1.832 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr5_+_176006993 1.642 NM_001006616
NM_012171
NM_130465
TSPAN17


tetraspanin 17


chr1_-_32574185 1.627 NM_023009
MARCKSL1
MARCKS-like 1
chr9_+_138680064 1.598 EGFL7
EGF-like-domain, multiple 7
chr19_+_40958206 1.584 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr10_+_75427853 1.556 NM_003373
NM_014000
VCL

vinculin

chr22_-_17546276 1.554 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_-_17489912 1.515 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chr22_-_17545872 1.513 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_+_18081968 1.508 NM_002688
SEPT5
septin 5
chr5_+_176786279 1.488 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr19_+_8384181 1.437 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr19_+_3045528 1.422 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr3_-_12983959 1.421 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr9_+_135314907 1.377 NM_001135775
NM_017586
C9orf7

chromosome 9 open reading frame 7

chr22_-_17546234 1.354 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr11_-_67329246 1.347 LOC645332
family with sequence similarity 86, member A pseudogene
chr5_+_176007095 1.345 TSPAN17
tetraspanin 17
chr1_+_30964199 1.315 LOC100129196
hypothetical LOC100129196
chr22_-_17489718 1.310 DGCR2
DiGeorge syndrome critical region gene 2
chr17_+_78630793 1.249 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr22_-_18635614 1.243 NM_023004
RTN4R
reticulon 4 receptor
chr11_-_33678861 1.218 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr9_+_132961683 1.214 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr19_+_7891884 1.212 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr22_+_20101661 1.204 NM_015094
HIC2
hypermethylated in cancer 2
chr1_+_3679168 1.196 NM_001163724
LOC388588
hypothetical protein LOC388588
chr19_+_4198049 1.191 NM_018074
CCDC94
coiled-coil domain containing 94
chr1_+_110554836 1.141 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chr1_+_984935 1.115 LOC100288175
hypothetical LOC100288175
chr19_+_3958690 1.025 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr19_-_7896974 1.021 NM_206833
CTXN1
cortexin 1
chr12_+_55896844 1.017 NM_007224
NXPH4
neurexophilin 4
chr5_+_176170041 0.998 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr11_-_69228286 0.998 NM_005117
FGF19
fibroblast growth factor 19
chr22_+_18085990 0.995 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr19_+_7891193 0.995 NM_003083
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr19_-_8361552 0.993 LOC100507567
hypothetical LOC100507567
chr7_+_45006289 0.979 NM_001167934
NM_001167935
NM_031443
CCM2


cerebral cavernous malformation 2


chr19_+_1397268 0.974 APC2
adenomatosis polyposis coli 2
chr22_+_18085891 0.966 SEPT5
septin 5
chr16_+_4948318 0.965 NM_014692
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr7_+_128257698 0.960 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr1_+_41022066 0.956 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr6_-_33393471 0.934 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr1_-_6243621 0.916 NM_207370
GPR153
G protein-coupled receptor 153
chr19_+_1220244 0.891 NM_001280
CIRBP
cold inducible RNA binding protein
chr6_-_33393696 0.885 NM_001145338
ZBTB22
zinc finger and BTB domain containing 22
chr15_+_38520594 0.881 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr13_+_90848875 0.880 NM_004466
GPC5
glypican 5
chr7_+_154720547 0.877 INSIG1
insulin induced gene 1
chr22_-_20419975 0.863 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr7_-_102044374 0.862 RASA4
RAS p21 protein activator 4
chr19_+_3045266 0.857 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr10_+_42892506 0.852 NM_020630
NM_020975
RET

ret proto-oncogene

chr11_-_565848 0.838 LOC143666
hypothetical LOC143666
chr1_-_3437834 0.833 MEGF6
multiple EGF-like-domains 6
chr1_-_3517918 0.829 NM_001409
MEGF6
multiple EGF-like-domains 6
chr6_-_31805547 0.828 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr6_-_31806012 0.822 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr9_+_138805581 0.815 NM_032928
TMEM141
transmembrane protein 141
chr9_-_138277467 0.808 NM_181701
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr7_+_128365226 0.807 NM_001098629
NM_001098630
IRF5

interferon regulatory factor 5

chr1_-_9892852 0.807 NM_001012329
NM_020248
CTNNBIP1

catenin, beta interacting protein 1

chr1_+_984972 0.801 LOC100288175
hypothetical LOC100288175
chr21_-_36450448 0.790 LOC100506428
hypothetical LOC100506428
chr7_+_150414704 0.783 NM_001042535
NM_031946
AGAP3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

chr22_+_18388633 0.782 C22orf25
chromosome 22 open reading frame 25
chr22_-_18384251 0.780 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr4_+_1764802 0.770 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr2_+_10101081 0.768 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr19_+_18069596 0.763 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr7_-_102044419 0.759 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr1_+_26728839 0.744 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_-_120715937 0.744 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr17_-_829655 0.738 NM_022463
NXN
nucleoredoxin
chrX_-_152804731 0.737 L1CAM
L1 cell adhesion molecule
chr1_+_26728846 0.730 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_+_53664386 0.728 CYTH2
cytohesin 2
chr1_+_26728827 0.725 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr9_-_135923373 0.724 BRD3
bromodomain containing 3
chr5_+_177473071 0.724 NM_015111
N4BP3
NEDD4 binding protein 3
chr16_-_342399 0.722 NM_003502
NM_181050
AXIN1

axin 1

chr6_-_31805932 0.719 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_+_3360880 0.711 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr16_+_670115 0.710 NM_005861
STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr1_+_12149637 0.709 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr22_-_29015452 0.697 NM_001037666
GATSL3
GATS protein-like 3
chr1_+_210672817 0.696 NM_013349
NENF
neuron derived neurotrophic factor
chr10_-_80875097 0.692 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr6_+_44299482 0.688 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr1_-_31484986 0.687 NKAIN1
Na+/K+ transporting ATPase interacting 1
chr16_+_87765661 0.686 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr5_+_10617431 0.684 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr21_+_46226072 0.676 NM_001848
COL6A1
collagen, type VI, alpha 1
chr19_-_18578631 0.673 NM_004750
CRLF1
cytokine receptor-like factor 1
chr19_+_45996881 0.672 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr7_+_72720093 0.672 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr7_-_102070473 0.671 NM_001114403
UPK3BL
POLR2J2
uroplakin 3B-like
polymerase (RNA) II (DNA directed) polypeptide J2
chr12_+_111980044 0.669 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr19_+_8361260 0.669 RAB11B
RAB11B, member RAS oncogene family
chr12_+_47498778 0.665 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr21_+_34367747 0.664 MRPS6
mitochondrial ribosomal protein S6
chr6_-_31890765 0.663 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr6_+_44299254 0.661 NM_001078175
NM_001078176
NM_001078177
SLC29A1


solute carrier family 29 (nucleoside transporters), member 1


chr17_-_39632845 0.660 ATXN7L3
ataxin 7-like 3
chr7_+_127079388 0.659 NM_014390
SND1
staphylococcal nuclease and tudor domain containing 1
chr9_+_138497767 0.658 NM_152571
C9orf163
chromosome 9 open reading frame 163
chr1_+_28458546 0.658 NM_031459
SESN2
sestrin 2
chr21_+_44544392 0.657 PFKL
phosphofructokinase, liver
chr1_+_29086156 0.655 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr10_+_73703682 0.655 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr22_+_17337970 0.654 DGCR5
DiGeorge syndrome critical region gene 5 (non-protein coding)
chr7_+_1536847 0.653 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_-_113059396 0.652 NM_005167
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr7_+_127079481 0.650 SND1
staphylococcal nuclease and tudor domain containing 1
chr1_+_29086206 0.645 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr15_-_73818013 0.638


chr6_-_42527760 0.637 NM_033502
TRERF1
transcriptional regulating factor 1
chr16_+_87047418 0.636 NM_153813
ZFPM1
zinc finger protein, multitype 1
chrX_-_48713194 0.635 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr8_+_8123513 0.634 FLJ10661
family with sequence similarity 86, member A pseudogene
chr19_+_51492136 0.634 NM_152795
HIF3A
hypoxia inducible factor 3, alpha subunit
chr11_+_63775567 0.631 NM_000932
NM_001184883
PLCB3

phospholipase C, beta 3 (phosphatidylinositol-specific)

chr19_-_10807866 0.630 NM_006858
TMED1
transmembrane emp24 protein transport domain containing 1
chr19_-_1543633 0.630 NM_003926
MBD3
methyl-CpG binding domain protein 3
chrX_+_128942435 0.630


chrX_+_15666312 0.627 NM_007220
CA5B
carbonic anhydrase VB, mitochondrial
chr15_+_39907447 0.624 NM_001114632
NM_001198588
NM_005090
JMJD7
JMJD7-PLA2G4B

jumonji domain containing 7
JMJD7-PLA2G4B readthrough

chr8_-_145661545 0.619 NM_032687
NM_001129888
CYHR1

cysteine/histidine-rich 1

chr19_-_43570503 0.615 NM_152657
GGN
gametogenetin
chr22_-_20551953 0.615 NM_002745
NM_138957
MAPK1

mitogen-activated protein kinase 1

chr4_+_3264509 0.614 RGS12
regulator of G-protein signaling 12
chr8_+_142207866 0.613 NM_014957
DENND3
DENN/MADD domain containing 3
chr1_+_945331 0.612 NM_198576
AGRN
agrin
chr21_+_44544349 0.607 NM_002626
PFKL
phosphofructokinase, liver
chr19_+_18608827 0.606 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr19_+_8361243 0.603 RAB11B
RAB11B, member RAS oncogene family
chr1_+_9571518 0.601 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr4_+_154606900 0.600 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr19_-_55524445 0.595 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_-_17047228 0.593 NM_001011699
NM_033417
HAUS8

HAUS augmin-like complex, subunit 8

chr19_-_1543691 0.590 MBD3
methyl-CpG binding domain protein 3
chr22_-_20551937 0.589 MAPK1
mitogen-activated protein kinase 1
chr10_+_11824361 0.587 NM_024693
ECHDC3
enoyl CoA hydratase domain containing 3
chr9_+_130078321 0.587 C9orf119
chromosome 9 open reading frame 119
chr19_+_45996940 0.586 EGLN2
egl nine homolog 2 (C. elegans)
chr11_+_46325457 0.584 NM_003646
DGKZ
diacylglycerol kinase, zeta
chr3_-_46710137 0.584 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr9_+_139006663 0.580 NM_183241
C9orf142
chromosome 9 open reading frame 142
chr1_-_44912649 0.580 NM_024587
TMEM53
transmembrane protein 53
chr6_+_35528093 0.579 NM_021922
FANCE
Fanconi anemia, complementation group E
chr19_+_8361200 0.579 NM_004218
RAB11B
RAB11B, member RAS oncogene family
chr20_-_51644187 0.578 ZNF217
zinc finger protein 217
chr11_+_61032847 0.577 NM_001145077
LRRC10B
leucine rich repeat containing 10B
chr9_-_130078017 0.577 NM_004486
GOLGA2
golgin A2
chr8_-_145119627 0.573 NM_201378
PLEC
plectin
chr19_-_11234117 0.572 NM_020812
DOCK6
dedicator of cytokinesis 6
chr1_-_44912704 0.571 TMEM53
transmembrane protein 53
chr1_-_38285033 0.570 NM_002699
POU3F1
POU class 3 homeobox 1
chr9_+_138805637 0.570 TMEM141
transmembrane protein 141
chr6_+_35528127 0.566 FANCE
Fanconi anemia, complementation group E
chr9_+_130078242 0.564 NM_001040011
C9orf119
chromosome 9 open reading frame 119
chr19_-_41236959 0.562 THAP8
THAP domain containing 8
chr17_-_40401138 0.562 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chr7_-_105712646 0.558 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr7_+_154720416 0.556 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr19_+_50041387 0.554 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr3_+_38470782 0.554 NM_001106
ACVR2B
activin A receptor, type IIB
chr1_-_48235148 0.551 NM_001194986
LOC388630
UPF0632 protein A
chr16_+_11669736 0.548 NM_003498
SNN
stannin
chr11_-_67153959 0.545 NM_181843
NUDT8
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr7_+_128365482 0.544 NM_032643
IRF5
interferon regulatory factor 5
chr6_+_31741635 0.543 NM_001320
CSNK2B
casein kinase 2, beta polypeptide
chr16_-_65742323 0.542 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr8_-_22044463 0.540 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr1_-_2333800 0.539 PEX10
peroxisomal biogenesis factor 10
chr7_+_127015650 0.539 NM_001662
ARF5
ADP-ribosylation factor 5
chr1_-_42274160 0.536


chr22_+_22907417 0.534 SUSD2
sushi domain containing 2
chr1_+_41057186 0.533 KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr17_+_75849221 0.532 NM_020914
NM_020954
RNF213

ring finger protein 213

chr19_+_7801110 0.532 NM_145245
EVI5L
ecotropic viral integration site 5-like
chr19_+_4423149 0.530 NM_001001520
NM_032631
HDGFRP2

hepatoma-derived growth factor-related protein 2

chr8_-_143692814 0.530 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr5_+_176726918 0.529 RGS14
regulator of G-protein signaling 14
chr21_+_34367678 0.526 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr1_+_6767968 0.526 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr19_+_10843244 0.523 NM_199141
CARM1
coactivator-associated arginine methyltransferase 1
chr17_-_70380663 0.522 NM_004110
NM_024417
FDXR

ferredoxin reductase


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.06 6.36e-14 GO:0009987 cellular process
1.09 4.45e-09 GO:0044237 cellular metabolic process
1.12 1.29e-08 GO:0044260 cellular macromolecule metabolic process
1.09 1.40e-05 GO:0043170 macromolecule metabolic process
1.16 2.95e-05 GO:0006464 protein modification process
1.14 4.07e-05 GO:0044267 cellular protein metabolic process
1.07 9.54e-05 GO:0050794 regulation of cellular process
1.07 1.21e-04 GO:0050789 regulation of biological process
1.15 1.87e-04 GO:0043412 macromolecule modification
1.07 2.31e-04 GO:0008152 metabolic process
1.07 2.98e-04 GO:0044238 primary metabolic process
1.14 4.14e-04 GO:0048523 negative regulation of cellular process
1.11 4.87e-04 GO:0016043 cellular component organization
1.21 5.66e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.12 6.08e-04 GO:0071842 cellular component organization at cellular level
1.13 8.13e-04 GO:0048522 positive regulation of cellular process
1.16 1.06e-03 GO:0009653 anatomical structure morphogenesis
1.13 1.14e-03 GO:0048519 negative regulation of biological process
1.06 1.18e-03 GO:0065007 biological regulation
1.12 1.33e-03 GO:0048518 positive regulation of biological process
1.16 1.59e-03 GO:0007399 nervous system development
1.15 2.19e-03 GO:0023051 regulation of signaling
1.21 2.56e-03 GO:0008219 cell death
1.10 2.58e-03 GO:0071840 cellular component organization or biogenesis
1.27 3.24e-03 GO:0051253 negative regulation of RNA metabolic process
1.20 3.37e-03 GO:0022008 neurogenesis
1.11 3.54e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.20 4.99e-03 GO:0016265 death
1.26 6.03e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.20 9.12e-03 GO:0048699 generation of neurons
1.24 1.01e-02 GO:0010629 negative regulation of gene expression
1.09 1.03e-02 GO:0031323 regulation of cellular metabolic process
1.09 2.03e-02 GO:0032502 developmental process
1.12 2.14e-02 GO:0048869 cellular developmental process
1.10 2.20e-02 GO:0019538 protein metabolic process
1.09 2.29e-02 GO:0080090 regulation of primary metabolic process
1.08 2.88e-02 GO:0019222 regulation of metabolic process
1.09 3.14e-02 GO:0048856 anatomical structure development
1.63 3.97e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.22 4.39e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.24 4.58e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 3.34e-31 GO:0044424 intracellular part
1.08 1.98e-30 GO:0005622 intracellular
1.10 3.58e-26 GO:0043226 organelle
1.10 6.00e-26 GO:0043229 intracellular organelle
1.10 2.16e-23 GO:0043227 membrane-bounded organelle
1.10 2.37e-23 GO:0043231 intracellular membrane-bounded organelle
1.10 1.89e-18 GO:0005737 cytoplasm
1.11 9.67e-13 GO:0044446 intracellular organelle part
1.11 2.12e-12 GO:0044422 organelle part
1.11 1.13e-11 GO:0005634 nucleus
1.10 1.63e-10 GO:0044444 cytoplasmic part
1.03 2.18e-07 GO:0044464 cell part
1.03 2.44e-07 GO:0005623 cell
1.17 1.14e-06 GO:0031981 nuclear lumen
1.20 2.05e-06 GO:0005654 nucleoplasm
1.15 2.99e-06 GO:0005829 cytosol
1.15 5.31e-06 GO:0044428 nuclear part
1.14 2.88e-05 GO:0070013 intracellular organelle lumen
1.16 4.09e-05 GO:0012505 endomembrane system
1.13 8.70e-05 GO:0043233 organelle lumen
1.11 1.93e-04 GO:0043234 protein complex
1.12 3.11e-04 GO:0031974 membrane-enclosed lumen
1.30 5.71e-04 GO:0045202 synapse
1.23 1.81e-03 GO:0030054 cell junction
1.12 1.92e-03 GO:0031090 organelle membrane
1.54 4.73e-03 GO:0005925 focal adhesion
1.20 4.94e-03 GO:0031410 cytoplasmic vesicle
1.20 6.11e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.31 6.76e-03 GO:0044456 synapse part
1.19 8.27e-03 GO:0031988 membrane-bounded vesicle
1.41 9.95e-03 GO:0030136 clathrin-coated vesicle
1.16 1.28e-02 GO:0005794 Golgi apparatus
1.55 1.47e-02 GO:0008021 synaptic vesicle
1.18 1.75e-02 GO:0031982 vesicle
1.48 2.01e-02 GO:0030055 cell-substrate junction
1.38 2.70e-02 GO:0070161 anchoring junction
1.47 4.45e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 8.93e-24 GO:0005515 protein binding
1.06 6.30e-17 GO:0005488 binding
1.22 1.07e-03 GO:0019899 enzyme binding
1.17 7.86e-03 GO:0001071 nucleic acid binding transcription factor activity
1.17 7.86e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 8.64e-03 GO:0016564 transcription repressor activity
1.28 1.14e-02 GO:0000988 protein binding transcription factor activity
1.28 1.14e-02 GO:0000989 transcription factor binding transcription factor activity
1.23 1.32e-02 GO:0008092 cytoskeletal protein binding
1.17 1.46e-02 GO:0030528 transcription regulator activity
1.27 1.47e-02 GO:0003712 transcription cofactor activity
1.12 2.97e-02 GO:0016740 transferase activity
1.20 3.33e-02 GO:0043565 sequence-specific DNA binding
1.56 4.22e-02 GO:0019199 transmembrane receptor protein kinase activity
1.24 4.30e-02 GO:0019904 protein domain specific binding