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• Activity deltas table
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Motif ID: KLF4.p3

Z-value: 1.595

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_129962292	3.660	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr12_+_110328126	3.306	NM_005475	SH2B3	SH2B adaptor protein 3
chr1_+_32992131	3.191
chr9_+_132961723	2.549		AIF1L	allograft inflammatory factor 1-like
chr22_+_21817512	2.354	NM_004914	RAB36	RAB36, member RAS oncogene family
chr22_+_21742727	2.296		GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr1_-_1840564	2.171	NM_178545	TMEM52	transmembrane protein 52
chr7_-_158073121	2.045	NM_002847 NM_130842 NM_130843	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr21_+_44699796	2.025	NM_030891	LRRC3	leucine rich repeat containing 3
chr22_-_17546296	1.852	NM_005984	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_+_21742364	1.832	NM_002073	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr5_+_176006993	1.642	NM_001006616 NM_012171 NM_130465	TSPAN17	tetraspanin 17
chr1_-_32574185	1.627	NM_023009	MARCKSL1	MARCKS-like 1
chr9_+_138680064	1.598		EGFL7	EGF-like-domain, multiple 7
chr19_+_40958206	1.584	NM_001172630 NM_052948	ARHGAP33	Rho GTPase activating protein 33
chr10_+_75427853	1.556	NM_003373 NM_014000	VCL	vinculin
chr22_-_17546276	1.554		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_-_17489912	1.515	NM_001173533 NM_001173534 NM_001184781 NM_005137	DGCR2	DiGeorge syndrome critical region gene 2
chr22_-_17545872	1.513		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_+_18081968	1.508	NM_002688	SEPT5	septin 5
chr5_+_176786279	1.488	NM_001004105 NM_001004106 NM_002082	GRK6	G protein-coupled receptor kinase 6
chr19_+_8384181	1.437	NM_001005415 NM_001005416 NM_016496	MARCH2	membrane-associated ring finger (C3HC4) 2
chr19_+_3045528	1.422		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr3_-_12983959	1.421	NM_014869	IQSEC1	IQ motif and Sec7 domain 1
chr9_+_135314907	1.377	NM_001135775 NM_017586	C9orf7	chromosome 9 open reading frame 7
chr22_-_17546234	1.354		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr11_-_67329246	1.347		LOC645332	family with sequence similarity 86, member A pseudogene
chr5_+_176007095	1.345		TSPAN17	tetraspanin 17
chr1_+_30964199	1.315		LOC100129196	hypothetical LOC100129196
chr22_-_17489718	1.310		DGCR2	DiGeorge syndrome critical region gene 2
chr17_+_78630793	1.249	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr22_-_18635614	1.243	NM_023004	RTN4R	reticulon 4 receptor
chr11_-_33678861	1.218	NM_001166692	C11orf91	chromosome 11 open reading frame 91
chr9_+_132961683	1.214	NM_001185095 NM_001185096 NM_031426	AIF1L	allograft inflammatory factor 1-like
chr19_+_7891884	1.212		SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa
chr22_+_20101661	1.204	NM_015094	HIC2	hypermethylated in cancer 2
chr1_+_3679168	1.196	NM_001163724	LOC388588	hypothetical protein LOC388588
chr19_+_4198049	1.191	NM_018074	CCDC94	coiled-coil domain containing 94
chr1_+_110554836	1.141	NM_001039574 NM_004978	KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4
chr1_+_984935	1.115		LOC100288175	hypothetical LOC100288175
chr19_+_3958690	1.025	NM_015897	PIAS4	protein inhibitor of activated STAT, 4
chr19_-_7896974	1.021	NM_206833	CTXN1	cortexin 1
chr12_+_55896844	1.017	NM_007224	NXPH4	neurexophilin 4
chr5_+_176170041	0.998	NM_133369	UNC5A	unc-5 homolog A (C. elegans)
chr11_-_69228286	0.998	NM_005117	FGF19	fibroblast growth factor 19
chr22_+_18085990	0.995		SEPT5-GP1BB SEPT5	SEPT5-GP1BB read-through transcript septin 5
chr19_+_7891193	0.995	NM_003083	SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa
chr19_-_8361552	0.993		LOC100507567	hypothetical LOC100507567
chr7_+_45006289	0.979	NM_001167934 NM_001167935 NM_031443	CCM2	cerebral cavernous malformation 2
chr19_+_1397268	0.974		APC2	adenomatosis polyposis coli 2
chr22_+_18085891	0.966		SEPT5	septin 5
chr16_+_4948318	0.965	NM_014692	SEC14L5	SEC14-like 5 (S. cerevisiae)
chr7_+_128257698	0.960	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr1_+_41022066	0.956	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr6_-_33393471	0.934	NM_005453	ZBTB22	zinc finger and BTB domain containing 22
chr1_-_6243621	0.916	NM_207370	GPR153	G protein-coupled receptor 153
chr19_+_1220244	0.891	NM_001280	CIRBP	cold inducible RNA binding protein
chr6_-_33393696	0.885	NM_001145338	ZBTB22	zinc finger and BTB domain containing 22
chr15_+_38520594	0.881	NM_014952	BAHD1	bromo adjacent homology domain containing 1
chr13_+_90848875	0.880	NM_004466	GPC5	glypican 5
chr7_+_154720547	0.877		INSIG1	insulin induced gene 1
chr22_-_20419975	0.863	NM_013313	YPEL1	yippee-like 1 (Drosophila)
chr7_-_102044374	0.862		RASA4	RAS p21 protein activator 4
chr19_+_3045266	0.857	NM_002067	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr10_+_42892506	0.852	NM_020630 NM_020975	RET	ret proto-oncogene
chr11_-_565848	0.838		LOC143666	hypothetical LOC143666
chr1_-_3437834	0.833		MEGF6	multiple EGF-like-domains 6
chr1_-_3517918	0.829	NM_001409	MEGF6	multiple EGF-like-domains 6
chr6_-_31805547	0.828		DDAH2	dimethylarginine dimethylaminohydrolase 2
chr6_-_31806012	0.822	NM_013974	DDAH2	dimethylarginine dimethylaminohydrolase 2
chr9_+_138805581	0.815	NM_032928	TMEM141	transmembrane protein 141
chr9_-_138277467	0.808	NM_181701	QSOX2	quiescin Q6 sulfhydryl oxidase 2
chr7_+_128365226	0.807	NM_001098629 NM_001098630	IRF5	interferon regulatory factor 5
chr1_-_9892852	0.807	NM_001012329 NM_020248	CTNNBIP1	catenin, beta interacting protein 1
chr1_+_984972	0.801		LOC100288175	hypothetical LOC100288175
chr21_-_36450448	0.790		LOC100506428	hypothetical LOC100506428
chr7_+_150414704	0.783	NM_001042535 NM_031946	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr22_+_18388633	0.782		C22orf25	chromosome 22 open reading frame 25
chr22_-_18384251	0.780	NM_001670	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome
chr4_+_1764802	0.770	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr2_+_10101081	0.768	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr19_+_18069596	0.763	NM_015016	MAST3	microtubule associated serine/threonine kinase 3
chr7_-_102044419	0.759	NM_001079877 NM_006989	RASA4	RAS p21 protein activator 4
chr1_+_26728839	0.744		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_-_120715937	0.744	NM_019034	RHOF	ras homolog gene family, member F (in filopodia)
chr17_-_829655	0.738	NM_022463	NXN	nucleoredoxin
chrX_-_152804731	0.737		L1CAM	L1 cell adhesion molecule
chr1_+_26728846	0.730		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_+_53664386	0.728		CYTH2	cytohesin 2
chr1_+_26728827	0.725	NM_002953	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr9_-_135923373	0.724		BRD3	bromodomain containing 3
chr5_+_177473071	0.724	NM_015111	N4BP3	NEDD4 binding protein 3
chr16_-_342399	0.722	NM_003502 NM_181050	AXIN1	axin 1
chr6_-_31805932	0.719		DDAH2	dimethylarginine dimethylaminohydrolase 2
chr1_+_3360880	0.711	NM_014448	ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16
chr16_+_670115	0.710	NM_005861	STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr1_+_12149637	0.709	NM_001066	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr22_-_29015452	0.697	NM_001037666	GATSL3	GATS protein-like 3
chr1_+_210672817	0.696	NM_013349	NENF	neuron derived neurotrophic factor
chr10_-_80875097	0.692	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr6_+_44299482	0.688		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr1_-_31484986	0.687		NKAIN1	Na+/K+ transporting ATPase interacting 1
chr16_+_87765661	0.686	NM_004933	CDH15	cadherin 15, type 1, M-cadherin (myotubule)
chr5_+_10617431	0.684	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr21_+_46226072	0.676	NM_001848	COL6A1	collagen, type VI, alpha 1
chr19_-_18578631	0.673	NM_004750	CRLF1	cytokine receptor-like factor 1
chr19_+_45996881	0.672	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chr7_+_72720093	0.672	NM_001077621	VPS37D	vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr7_-_102070473	0.671	NM_001114403	UPK3BL POLR2J2	uroplakin 3B-like polymerase (RNA) II (DNA directed) polypeptide J2
chr12_+_111980044	0.669	NM_004416	DTX1	deltex homolog 1 (Drosophila)
chr19_+_8361260	0.669		RAB11B	RAB11B, member RAS oncogene family
chr12_+_47498778	0.665	NM_000725	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr21_+_34367747	0.664		MRPS6	mitochondrial ribosomal protein S6
chr6_-_31890765	0.663	NM_005527	HSPA1L	heat shock 70kDa protein 1-like
chr6_+_44299254	0.661	NM_001078175 NM_001078176 NM_001078177	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr17_-_39632845	0.660		ATXN7L3	ataxin 7-like 3
chr7_+_127079388	0.659	NM_014390	SND1	staphylococcal nuclease and tudor domain containing 1
chr9_+_138497767	0.658	NM_152571	C9orf163	chromosome 9 open reading frame 163
chr1_+_28458546	0.658	NM_031459	SESN2	sestrin 2
chr21_+_44544392	0.657		PFKL	phosphofructokinase, liver
chr1_+_29086156	0.655	NM_001166005 NM_001166007 NM_004437 NM_203342 NM_203343	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr10_+_73703682	0.655	NM_019058	DDIT4	DNA-damage-inducible transcript 4
chr22_+_17337970	0.654		DGCR5	DiGeorge syndrome critical region gene 5 (non-protein coding)
chr7_+_1536847	0.653	NM_002360	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_-_113059396	0.652	NM_005167	PPM1J	protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr7_+_127079481	0.650		SND1	staphylococcal nuclease and tudor domain containing 1
chr1_+_29086206	0.645		EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr15_-_73818013	0.638
chr6_-_42527760	0.637	NM_033502	TRERF1	transcriptional regulating factor 1
chr16_+_87047418	0.636	NM_153813	ZFPM1	zinc finger protein, multitype 1
chrX_-_48713194	0.635	NM_004979	KCND1	potassium voltage-gated channel, Shal-related subfamily, member 1
chr8_+_8123513	0.634		FLJ10661	family with sequence similarity 86, member A pseudogene
chr19_+_51492136	0.634	NM_152795	HIF3A	hypoxia inducible factor 3, alpha subunit
chr11_+_63775567	0.631	NM_000932 NM_001184883	PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)
chr19_-_10807866	0.630	NM_006858	TMED1	transmembrane emp24 protein transport domain containing 1
chr19_-_1543633	0.630	NM_003926	MBD3	methyl-CpG binding domain protein 3
chrX_+_128942435	0.630
chrX_+_15666312	0.627	NM_007220	CA5B	carbonic anhydrase VB, mitochondrial
chr15_+_39907447	0.624	NM_001114632 NM_001198588 NM_005090	JMJD7 JMJD7-PLA2G4B	jumonji domain containing 7 JMJD7-PLA2G4B readthrough
chr8_-_145661545	0.619	NM_032687 NM_001129888	CYHR1	cysteine/histidine-rich 1
chr19_-_43570503	0.615	NM_152657	GGN	gametogenetin
chr22_-_20551953	0.615	NM_002745 NM_138957	MAPK1	mitogen-activated protein kinase 1
chr4_+_3264509	0.614		RGS12	regulator of G-protein signaling 12
chr8_+_142207866	0.613	NM_014957	DENND3	DENN/MADD domain containing 3
chr1_+_945331	0.612	NM_198576	AGRN	agrin
chr21_+_44544349	0.607	NM_002626	PFKL	phosphofructokinase, liver
chr19_+_18608827	0.606	NM_018316	KLHL26	kelch-like 26 (Drosophila)
chr19_+_8361243	0.603		RAB11B	RAB11B, member RAS oncogene family
chr1_+_9571518	0.601	NM_001010866 NM_001130924	TMEM201	transmembrane protein 201
chr4_+_154606900	0.600	NM_001131007 NM_015196	KIAA0922	KIAA0922
chr19_-_55524445	0.595	NM_004977	KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_-_17047228	0.593	NM_001011699 NM_033417	HAUS8	HAUS augmin-like complex, subunit 8
chr19_-_1543691	0.590		MBD3	methyl-CpG binding domain protein 3
chr22_-_20551937	0.589		MAPK1	mitogen-activated protein kinase 1
chr10_+_11824361	0.587	NM_024693	ECHDC3	enoyl CoA hydratase domain containing 3
chr9_+_130078321	0.587		C9orf119	chromosome 9 open reading frame 119
chr19_+_45996940	0.586		EGLN2	egl nine homolog 2 (C. elegans)
chr11_+_46325457	0.584	NM_003646	DGKZ	diacylglycerol kinase, zeta
chr3_-_46710137	0.584	NM_001190707 NM_147129	ALS2CL	ALS2 C-terminal like
chr9_+_139006663	0.580	NM_183241	C9orf142	chromosome 9 open reading frame 142
chr1_-_44912649	0.580	NM_024587	TMEM53	transmembrane protein 53
chr6_+_35528093	0.579	NM_021922	FANCE	Fanconi anemia, complementation group E
chr19_+_8361200	0.579	NM_004218	RAB11B	RAB11B, member RAS oncogene family
chr20_-_51644187	0.578		ZNF217	zinc finger protein 217
chr11_+_61032847	0.577	NM_001145077	LRRC10B	leucine rich repeat containing 10B
chr9_-_130078017	0.577	NM_004486	GOLGA2	golgin A2
chr8_-_145119627	0.573	NM_201378	PLEC	plectin
chr19_-_11234117	0.572	NM_020812	DOCK6	dedicator of cytokinesis 6
chr1_-_44912704	0.571		TMEM53	transmembrane protein 53
chr1_-_38285033	0.570	NM_002699	POU3F1	POU class 3 homeobox 1
chr9_+_138805637	0.570		TMEM141	transmembrane protein 141
chr6_+_35528127	0.566		FANCE	Fanconi anemia, complementation group E
chr9_+_130078242	0.564	NM_001040011	C9orf119	chromosome 9 open reading frame 119
chr19_-_41236959	0.562		THAP8	THAP domain containing 8
chr17_-_40401138	0.562	NM_006688	C1QL1	complement component 1, q subcomponent-like 1
chr7_-_105712646	0.558	NM_005746	NAMPT	nicotinamide phosphoribosyltransferase
chr7_+_154720416	0.556	NM_005542 NM_198336 NM_198337	INSIG1	insulin induced gene 1
chr19_+_50041387	0.554		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr3_+_38470782	0.554	NM_001106	ACVR2B	activin A receptor, type IIB
chr1_-_48235148	0.551	NM_001194986	LOC388630	UPF0632 protein A
chr16_+_11669736	0.548	NM_003498	SNN	stannin
chr11_-_67153959	0.545	NM_181843	NUDT8	nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr7_+_128365482	0.544	NM_032643	IRF5	interferon regulatory factor 5
chr6_+_31741635	0.543	NM_001320	CSNK2B	casein kinase 2, beta polypeptide
chr16_-_65742323	0.542	NM_033309	B3GNT9	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr8_-_22044463	0.540	NM_005144 NM_018411	HR	hairless homolog (mouse)
chr1_-_2333800	0.539		PEX10	peroxisomal biogenesis factor 10
chr7_+_127015650	0.539	NM_001662	ARF5	ADP-ribosylation factor 5
chr1_-_42274160	0.536
chr22_+_22907417	0.534		SUSD2	sushi domain containing 2
chr1_+_41057186	0.533		KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr17_+_75849221	0.532	NM_020914 NM_020954	RNF213	ring finger protein 213
chr19_+_7801110	0.532	NM_145245	EVI5L	ecotropic viral integration site 5-like
chr19_+_4423149	0.530	NM_001001520 NM_032631	HDGFRP2	hepatoma-derived growth factor-related protein 2
chr8_-_143692814	0.530	NM_015193	ARC	activity-regulated cytoskeleton-associated protein
chr5_+_176726918	0.529		RGS14	regulator of G-protein signaling 14
chr21_+_34367678	0.526	NM_032476 NM_006933	MRPS6 SLC5A3	mitochondrial ribosomal protein S6 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr1_+_6767968	0.526	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr19_+_10843244	0.523	NM_199141	CARM1	coactivator-associated arginine methyltransferase 1
chr17_-_70380663	0.522	NM_004110 NM_024417	FDXR	ferredoxin reductase

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.06	6.36e-14	GO:0009987	cellular process
1.09	4.45e-09	GO:0044237	cellular metabolic process
1.12	1.29e-08	GO:0044260	cellular macromolecule metabolic process
1.09	1.40e-05	GO:0043170	macromolecule metabolic process
1.16	2.95e-05	GO:0006464	protein modification process
1.14	4.07e-05	GO:0044267	cellular protein metabolic process
1.07	9.54e-05	GO:0050794	regulation of cellular process
1.07	1.21e-04	GO:0050789	regulation of biological process
1.15	1.87e-04	GO:0043412	macromolecule modification
1.07	2.31e-04	GO:0008152	metabolic process
1.07	2.98e-04	GO:0044238	primary metabolic process
1.14	4.14e-04	GO:0048523	negative regulation of cellular process
1.11	4.87e-04	GO:0016043	cellular component organization
1.21	5.66e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.12	6.08e-04	GO:0071842	cellular component organization at cellular level
1.13	8.13e-04	GO:0048522	positive regulation of cellular process
1.16	1.06e-03	GO:0009653	anatomical structure morphogenesis
1.13	1.14e-03	GO:0048519	negative regulation of biological process
1.06	1.18e-03	GO:0065007	biological regulation
1.12	1.33e-03	GO:0048518	positive regulation of biological process
1.16	1.59e-03	GO:0007399	nervous system development
1.15	2.19e-03	GO:0023051	regulation of signaling
1.21	2.56e-03	GO:0008219	cell death
1.10	2.58e-03	GO:0071840	cellular component organization or biogenesis
1.27	3.24e-03	GO:0051253	negative regulation of RNA metabolic process
1.20	3.37e-03	GO:0022008	neurogenesis
1.11	3.54e-03	GO:0071841	cellular component organization or biogenesis at cellular level
1.20	4.99e-03	GO:0016265	death
1.26	6.03e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.20	9.12e-03	GO:0048699	generation of neurons
1.24	1.01e-02	GO:0010629	negative regulation of gene expression
1.09	1.03e-02	GO:0031323	regulation of cellular metabolic process
1.09	2.03e-02	GO:0032502	developmental process
1.12	2.14e-02	GO:0048869	cellular developmental process
1.10	2.20e-02	GO:0019538	protein metabolic process
1.09	2.29e-02	GO:0080090	regulation of primary metabolic process
1.08	2.88e-02	GO:0019222	regulation of metabolic process
1.09	3.14e-02	GO:0048856	anatomical structure development
1.63	3.97e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.22	4.39e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.24	4.58e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.09	3.34e-31	GO:0044424	intracellular part
1.08	1.98e-30	GO:0005622	intracellular
1.10	3.58e-26	GO:0043226	organelle
1.10	6.00e-26	GO:0043229	intracellular organelle
1.10	2.16e-23	GO:0043227	membrane-bounded organelle
1.10	2.37e-23	GO:0043231	intracellular membrane-bounded organelle
1.10	1.89e-18	GO:0005737	cytoplasm
1.11	9.67e-13	GO:0044446	intracellular organelle part
1.11	2.12e-12	GO:0044422	organelle part
1.11	1.13e-11	GO:0005634	nucleus
1.10	1.63e-10	GO:0044444	cytoplasmic part
1.03	2.18e-07	GO:0044464	cell part
1.03	2.44e-07	GO:0005623	cell
1.17	1.14e-06	GO:0031981	nuclear lumen
1.20	2.05e-06	GO:0005654	nucleoplasm
1.15	2.99e-06	GO:0005829	cytosol
1.15	5.31e-06	GO:0044428	nuclear part
1.14	2.88e-05	GO:0070013	intracellular organelle lumen
1.16	4.09e-05	GO:0012505	endomembrane system
1.13	8.70e-05	GO:0043233	organelle lumen
1.11	1.93e-04	GO:0043234	protein complex
1.12	3.11e-04	GO:0031974	membrane-enclosed lumen
1.30	5.71e-04	GO:0045202	synapse
1.23	1.81e-03	GO:0030054	cell junction
1.12	1.92e-03	GO:0031090	organelle membrane
1.54	4.73e-03	GO:0005925	focal adhesion
1.20	4.94e-03	GO:0031410	cytoplasmic vesicle
1.20	6.11e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.31	6.76e-03	GO:0044456	synapse part
1.19	8.27e-03	GO:0031988	membrane-bounded vesicle
1.41	9.95e-03	GO:0030136	clathrin-coated vesicle
1.16	1.28e-02	GO:0005794	Golgi apparatus
1.55	1.47e-02	GO:0008021	synaptic vesicle
1.18	1.75e-02	GO:0031982	vesicle
1.48	2.01e-02	GO:0030055	cell-substrate junction
1.38	2.70e-02	GO:0070161	anchoring junction
1.47	4.45e-02	GO:0005924	cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.12	8.93e-24	GO:0005515	protein binding
1.06	6.30e-17	GO:0005488	binding
1.22	1.07e-03	GO:0019899	enzyme binding
1.17	7.86e-03	GO:0001071	nucleic acid binding transcription factor activity
1.17	7.86e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.31	8.64e-03	GO:0016564	transcription repressor activity
1.28	1.14e-02	GO:0000988	protein binding transcription factor activity
1.28	1.14e-02	GO:0000989	transcription factor binding transcription factor activity
1.23	1.32e-02	GO:0008092	cytoskeletal protein binding
1.17	1.46e-02	GO:0030528	transcription regulator activity
1.27	1.47e-02	GO:0003712	transcription cofactor activity
1.12	2.97e-02	GO:0016740	transferase activity
1.20	3.33e-02	GO:0043565	sequence-specific DNA binding
1.56	4.22e-02	GO:0019199	transmembrane receptor protein kinase activity
1.24	4.30e-02	GO:0019904	protein domain specific binding