Motif ID: PPARG.p2

Z-value: 1.448


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PPARGchr3_+_12305336-0.836.2e-05Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_54361216 5.914 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr19_+_531666 5.177 BSG
basigin (Ok blood group)
chr21_-_35153664 2.390 RUNX1
runt-related transcription factor 1
chr1_+_201541241 2.277 BTG2
BTG family, member 2
chr8_+_145692916 1.907 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr1_+_201541269 1.867 NM_006763
BTG2
BTG family, member 2
chr1_-_24342158 1.807 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr19_+_53819460 1.623 SPHK2
sphingosine kinase 2
chr14_+_104117100 1.581 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr19_-_60432443 1.579 NM_173804
TMEM86B
transmembrane protein 86B
chr22_+_21006814 1.501


chr19_+_3457264 1.389 NM_016263
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr7_+_1543644 1.312 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr22_-_21814208 1.297 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr1_+_15955719 1.269 FBLIM1
filamin binding LIM protein 1
chr9_+_130428519 1.261 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr16_+_84204424 1.251 NM_014615
KIAA0182
KIAA0182
chr16_-_3567354 1.228 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr7_-_156161130 1.139


chr5_-_179951071 1.112 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr1_-_3806564 1.090 C1orf174
chromosome 1 open reading frame 174
chr1_-_3806683 1.037 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr19_-_55708936 1.018 NM_001114598
ASPDH
aspartate dehydrogenase domain containing
chr7_-_128330615 0.910 KCP
kielin/chordin-like protein
chr11_-_67528103 0.903 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr1_+_44208236 0.895 NM_001039589
NM_001384
DPH2

DPH2 homolog (S. cerevisiae)

chr19_+_53650577 0.884 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr1_-_37991160 0.872 EPHA10
EPH receptor A10
chr16_+_82782223 0.855 NM_001145400
NM_139174
ADAD2

adenosine deaminase domain containing 2

chr11_+_303852 0.853 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr19_+_7874764 0.846 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr9_+_138966588 0.836 NM_178536
LCN12
lipocalin 12
chr19_+_540849 0.834 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr22_+_21484240 0.821


chr7_+_142270634 0.816 EPHB6
EPH receptor B6
chr19_+_7874765 0.813 MAP2K7
mitogen-activated protein kinase kinase 7
chr8_-_27906287 0.792 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr15_+_72687765 0.790 NM_003992
CLK3
CDC-like kinase 3
chr16_+_56211150 0.788 GPR56
G protein-coupled receptor 56
chr19_+_7874774 0.779 MAP2K7
mitogen-activated protein kinase kinase 7
chr3_+_8750485 0.764 NM_033337
NM_001234
CAV3

caveolin 3

chr19_+_7874820 0.763 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_-_5790702 0.745 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr19_+_7874762 0.730 MAP2K7
mitogen-activated protein kinase kinase 7
chr11_+_9736408 0.710 LOC283104
hypothetical LOC283104
chr19_+_7874701 0.689 MAP2K7
mitogen-activated protein kinase kinase 7
chr1_-_6448737 0.683 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr19_+_951295 0.640 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr19_+_18312365 0.632 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr1_-_6341553 0.632 NM_181866
ACOT7
acyl-CoA thioesterase 7
chr19_-_5821546 0.589 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr1_-_6474346 0.561 NM_020631
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_-_31736488 0.543 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr11_+_60366004 0.541 NM_024098
CCDC86
coiled-coil domain containing 86
chr15_+_72540655 0.538 LOC440288
similar to FLJ16518 protein
chr12_-_50871953 0.529 NM_001081492
NM_182507
KRT80

keratin 80

chr19_+_54352809 0.518 NM_001195227
NM_017636
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr9_-_33437527 0.483 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr7_-_100262971 0.465 NM_004444
EPHB4
EPH receptor B4
chr3_+_44667504 0.451 ZNF35
zinc finger protein 35
chr4_-_9632192 0.443 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr7_-_99365178 0.442 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr1_-_149385556 0.431 NM_001178061
NM_001178062
NM_030913
SEMA6C


sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C


chr19_+_1442000 0.429 NM_138393
REEP6
receptor accessory protein 6
chr19_+_1389397 0.416 RPS15
ribosomal protein S15
chr1_-_204455269 0.401 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr17_-_36981830 0.396 NM_000226
KRT9
keratin 9
chr16_-_28425632 0.394 NM_145659
IL27
interleukin 27
chr1_+_199884072 0.394 NM_020443
NAV1
neuron navigator 1
chr16_-_4105703 0.391 ADCY9
adenylate cyclase 9
chr22_+_48698337 0.390 CRELD2
cysteine-rich with EGF-like domains 2
chr22_+_20880159 0.388 IGLV6-57
immunoglobulin lambda variable 6-57
chr16_+_1143241 0.376 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr8_-_132122016 0.374 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr1_+_17121012 0.373 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr22_+_21011653 0.370


chr11_-_8695974 0.364 ST5
suppression of tumorigenicity 5
chr22_+_21559959 0.363 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr12_-_51887266 0.359 NM_000889
ITGB7
integrin, beta 7
chr1_+_151655623 0.357 NM_176823
S100A7A
S100 calcium binding protein A7A
chr17_+_4972410 0.356 NM_004505
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr17_-_59327602 0.355 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr11_+_117452936 0.353 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr17_-_2250967 0.349 NM_020310
MNT
MAX binding protein
chr19_+_54352843 0.341 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr9_+_131467837 0.340 PRRX2
paired related homeobox 2
chr8_-_70907957 0.338 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr14_+_104244998 0.329 INF2
inverted formin, FH2 and WH2 domain containing
chr11_-_8982107 0.324 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr7_-_150561233 0.322


chr22_+_28032950 0.317 NM_006478
NM_152236
NM_152237
GAS2L1


growth arrest-specific 2 like 1


chr8_-_97316933 0.309 NM_006294
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr9_-_130006309 0.308 NM_001131015
NM_012127
CIZ1

CDKN1A interacting zinc finger protein 1

chr17_+_24095135 0.308 NM_004295
TRAF4
TNF receptor-associated factor 4
chr7_-_128337997 0.307 NM_001135914
NM_199349
KCP

kielin/chordin-like protein

chr15_-_68128924 0.304 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr8_-_107851593 0.302 NM_139166
ABRA
actin-binding Rho activating protein
chr22_+_20880112 0.301


chr22_+_18388602 0.300 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr7_+_128367961 0.297 NM_001098627
IRF5
interferon regulatory factor 5
chr3_-_12680329 0.296 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr15_-_72540484 0.296 UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr19_-_16111695 0.296


chr11_+_64079665 0.291 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr19_+_56337368 0.281 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr8_+_128875902 0.280 PVT1
Pvt1 oncogene (non-protein coding)
chr11_+_64737886 0.280 NM_001004326
SLC22A20
solute carrier family 22, member 20
chr15_+_79304694 0.280 NM_172217
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr22_+_21042091 0.275 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr9_-_137731139 0.274 NM_001012415
NM_001101677
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr1_+_68070573 0.273


chr8_+_143542378 0.272 NM_001702
BAI1
brain-specific angiogenesis inhibitor 1
chr11_+_268569 0.271 NM_138329
NLRP6
NLR family, pyrin domain containing 6
chr7_+_30917939 0.270 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr15_-_72540518 0.267 UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr22_-_31183372 0.266 NM_174932
BPIL2
bactericidal/permeability-increasing protein-like 2
chr1_-_19058741 0.262 NM_152232
TAS1R2
taste receptor, type 1, member 2
chr15_-_38908197 0.262 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D

chr9_-_129564517 0.260 NM_001142532
NM_001142531
SH2D3C

SH2 domain containing 3C

chr1_-_31003181 0.258 LAPTM5
lysosomal protein transmembrane 5
chr3_-_46710137 0.257 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr1_-_31003260 0.256 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr10_-_99042381 0.252 NM_032900
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 read-through transcript
Rho GTPase activating protein 19
chr1_+_16566169 0.252 NM_001114600
NM_015609
C1orf144

chromosome 1 open reading frame 144

chr19_-_54618410 0.252 NM_178449
PTH2
parathyroid hormone 2
chr19_-_59438411 0.247 NM_024318
LILRB3
LILRA6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr11_+_63765106 0.245 NM_001135208
FKBP2
FK506 binding protein 2, 13kDa
chr21_-_42644138 0.243 NM_005423
TFF2
trefoil factor 2
chr19_-_14447163 0.242 NM_000955
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr12_+_108149558 0.239 ACACB
acetyl-CoA carboxylase beta
chr9_-_34448477 0.233 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184944
NM_001184945
NM_147202
C9orf25






chromosome 9 open reading frame 25






chr22_+_18388633 0.231 C22orf25
chromosome 22 open reading frame 25
chr10_-_99042419 0.231 ARHGAP19
Rho GTPase activating protein 19
chr10_+_74540215 0.231 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr19_+_19487535 0.231 NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr19_-_16875407 0.230 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr15_-_72540543 0.229 NM_032907
NM_201265
UBL7

ubiquitin-like 7 (bone marrow stromal cell-derived)

chr17_+_71586857 0.228 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr9_-_91284430 0.222 NM_001142287
NM_006378
SEMA4D

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

chr6_-_31890765 0.219 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr10_-_98336548 0.213 TM9SF3
transmembrane 9 superfamily member 3
chr6_+_31903374 0.212 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr1_-_94359266 0.210 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr19_-_44060729 0.207 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr2_+_112612429 0.204 NM_001128165
NM_153214
FBLN7

fibulin 7

chr22_+_21094094 0.204


chr3_+_69895310 0.202 NM_001184967
MITF
microphthalmia-associated transcription factor
chr1_+_559618 0.199


chr17_+_16259573 0.198 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr17_+_39603599 0.196 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr5_+_149717394 0.192 NM_000356
NM_001008657
NM_001135243
NM_001135244
NM_001135245
NM_001195141
TCOF1





Treacher Collins-Franceschetti syndrome 1





chr7_+_150390566 0.188 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr19_-_60382529 0.188 SYT5
synaptotagmin V
chr8_-_143864933 0.188 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr1_+_33003847 0.187 KIAA1522
KIAA1522
chr19_+_702108 0.186 NM_173481
C19orf21
chromosome 19 open reading frame 21
chr17_+_41278035 0.184 NM_175882
IMP5
intramembrane protease 5
chr22_+_36632242 0.183 NM_033386
MICALL1
MICAL-like 1
chr16_+_56211410 0.183 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56

chr19_+_18608827 0.182 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr1_-_16355013 0.181 NM_004431
EPHA2
EPH receptor A2
chr5_-_179040580 0.180 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chrX_+_51944658 0.175 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr1_-_158161924 0.174 TAGLN2
transgelin 2
chr1_-_158161902 0.172 NM_003564
TAGLN2
transgelin 2
chr1_-_158161898 0.172 TAGLN2
transgelin 2
chr17_+_72883759 0.172 NM_001113494
SEPT9
septin 9
chr21_+_44002290 0.172 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr6_+_31891509 0.170 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr3_-_15515382 0.169 NM_080538
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr11_+_384199 0.167 NM_007183
PKP3
plakophilin 3
chr19_+_16860807 0.165 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr11_+_68572890 0.165 NM_139075
TPCN2
two pore segment channel 2
chrX_+_26120477 0.161 NM_173523
MAGEB6
melanoma antigen family B, 6
chr15_+_55786145 0.158 NM_001018102
NM_015532
GRINL1A

glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A

chr17_-_37590910 0.158 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr22_+_48698282 0.156 NM_001135101
NM_024324
CRELD2

cysteine-rich with EGF-like domains 2

chr19_-_16111594 0.155


chr17_-_8756524 0.155 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr1_-_158161877 0.154 TAGLN2
transgelin 2
chr3_+_52786642 0.153 NM_002215
ITIH1
inter-alpha (globulin) inhibitor H1
chr10_-_11976704 0.152 LOC219731
hypothetical LOC219731
chr15_+_55786212 0.150 GRINL1A
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
chr9_-_129719031 0.150 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr17_+_75319476 0.150 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr1_-_41259973 0.147 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr1_+_31655607 0.146 NM_001199037
SERINC2
serine incorporator 2
chr11_-_1549719 0.144 NM_004420
DUSP8
dual specificity phosphatase 8
chr1_-_149955870 0.143 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr5_-_178983281 0.142 NM_005520
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr11_-_117521344 0.141 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr9_+_139245029 0.140 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr2_+_220200530 0.140 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr1_+_201286933 0.139 NM_015053
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr12_-_94914133 0.138 NM_002108
HAL
histidine ammonia-lyase
chr11_+_712282 0.135 EPS8L2
EPS8-like 2
chr3_+_48482213 0.133 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr19_-_14085979 0.133 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr19_-_54636425 0.129 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr2_+_219818428 0.129 NM_001008910
STK16
serine/threonine kinase 16

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.76 1.26e-03 GO:0044459 plasma membrane part
1.97 8.61e-03 GO:0005887 integral to plasma membrane
1.93 1.28e-02 GO:0031226 intrinsic to plasma membrane
1.43 1.53e-02 GO:0005886 plasma membrane
1.43 1.57e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.06 3.73e-03 GO:0005215 transporter activity
14.11 4.17e-02 GO:0005003 ephrin receptor activity