Motif ID: GATA1..3.p2

Z-value: 1.914


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA3chr10_+_8136778-0.514.4e-02Click!
GATA2chr3_-_1296893940.116.9e-01Click!
GATA1chrX_+_485299050.078.1e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_170864111 2.635 NM_004991
MECOM
MDS1 and EVI1 complex locus
chr12_+_1608672 2.184 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chrX_-_57953578 2.108 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr17_-_7036490 2.016


chrX_+_53095230 1.980 NM_018969
GPR173
G protein-coupled receptor 173
chrX_-_50403412 1.972 SHROOM4
shroom family member 4
chr18_+_19706979 1.827 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chrX_-_63362227 1.822 NM_130388
ASB12
ankyrin repeat and SOCS box containing 12
chrX_+_41191630 1.772 NM_022567
NYX
nyctalopin
chr5_-_160044844 1.687 ATP10B
ATPase, class V, type 10B
chrX_-_152889815 1.649 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr15_+_100175888 1.581 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chrX_-_55037235 1.555 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr21_-_35153664 1.535 RUNX1
runt-related transcription factor 1
chrX_+_110252960 1.532 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr12_+_93066370 1.531 NM_005761
PLXNC1
plexin C1
chr5_+_180514548 1.522 NM_206880
OR2V2
olfactory receptor, family 2, subfamily V, member 2
chrX_-_110541029 1.450 NM_000555
DCX
doublecortin
chr9_-_34387786 1.438 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr11_-_16380967 1.427 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
2.25 1.43e-38 GO:0007608 sensory perception of smell
2.09 3.61e-33 GO:0007606 sensory perception of chemical stimulus
1.76 3.01e-29 GO:0007600 sensory perception
1.66 2.99e-02 GO:0045165 cell fate commitment
1.62 4.58e-34 GO:0050877 neurological system process
1.54 6.27e-33 GO:0003008 system process
1.49 7.69e-05 GO:0007268 synaptic transmission
1.46 5.59e-05 GO:0019226 transmission of nerve impulse
1.46 5.59e-05 GO:0035637 multicellular organismal signaling
1.45 7.63e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.45 3.26e-02 GO:0060284 regulation of cell development
1.44 1.17e-07 GO:0007267 cell-cell signaling
1.44 1.70e-03 GO:0032583 regulation of gene-specific transcription
1.42 7.59e-04 GO:0007417 central nervous system development
1.41 4.12e-02 GO:0007420 brain development
1.37 2.34e-04 GO:0030182 neuron differentiation
1.34 4.82e-10 GO:0007399 nervous system development
1.34 1.36e-04 GO:0048699 generation of neurons
1.33 2.00e-05 GO:0007154 cell communication
1.33 4.09e-02 GO:0048666 neuron development

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.57 4.21e-02 GO:0045211 postsynaptic membrane
1.47 2.40e-03 GO:0044456 synapse part
1.45 1.66e-04 GO:0045202 synapse
1.42 9.08e-04 GO:0043005 neuron projection
1.23 4.28e-18 GO:0005886 plasma membrane
1.22 3.48e-17 GO:0071944 cell periphery
1.12 5.44e-06 GO:0031224 intrinsic to membrane
1.12 8.18e-06 GO:0016021 integral to membrane
1.10 5.45e-05 GO:0044425 membrane part
1.09 7.60e-06 GO:0016020 membrane
1.03 3.28e-04 GO:0005623 cell
1.03 4.01e-04 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
2.58 3.74e-02 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
2.31 1.15e-40 GO:0004984 olfactory receptor activity
1.94 2.10e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.94 1.13e-02 GO:0005230 extracellular ligand-gated ion channel activity
1.87 2.89e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.82 3.85e-36 GO:0004930 G-protein coupled receptor activity
1.64 4.78e-02 GO:0015276 ligand-gated ion channel activity
1.64 4.78e-02 GO:0022834 ligand-gated channel activity
1.63 4.02e-04 GO:0000975 regulatory region DNA binding
1.63 4.02e-04 GO:0001067 regulatory region nucleic acid binding
1.63 4.02e-04 GO:0044212 transcription regulatory region DNA binding
1.62 1.10e-03 GO:0010843 promoter binding
1.61 8.22e-32 GO:0004888 transmembrane receptor activity
1.51 4.90e-04 GO:0022836 gated channel activity
1.49 1.94e-28 GO:0004872 receptor activity
1.41 1.27e-24 GO:0004871 signal transducer activity
1.41 1.27e-24 GO:0060089 molecular transducer activity
1.39 5.44e-06 GO:0043565 sequence-specific DNA binding
1.37 1.69e-02 GO:0015267 channel activity
1.37 1.95e-02 GO:0022803 passive transmembrane transporter activity