Motif ID: CEBPA,B_DDIT3.p2

Z-value: 0.897


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CEBPAchr19_-_384852810.702.3e-03Click!
DDIT3chr12_-_562005470.165.5e-01Click!
CEBPBchr20_+_482408670.048.7e-01Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_116125123 2.005 NM_000607
ORM1
orosomucoid 1
chr17_-_36346240 1.768 KRT23
keratin 23 (histone deacetylase inducible)
chr1_+_149221122 1.410 NM_003568
ANXA9
annexin A9
chr6_+_167624792 1.228 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr19_-_40684638 1.064 NM_001035516
DMKN
dermokine
chr6_+_12825022 1.013 PHACTR1
phosphatase and actin regulator 1
chr1_-_20122638 0.943 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr10_+_85994788 0.881 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr8_+_124263932 0.881 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr4_-_153820535 0.798 NM_152680
TMEM154
transmembrane protein 154
chr1_-_21373816 0.794 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr11_-_69228286 0.769 NM_005117
FGF19
fibroblast growth factor 19
chr6_+_12824873 0.753 PHACTR1
phosphatase and actin regulator 1
chr22_+_21384862 0.731 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr17_-_45280377 0.726 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr16_+_27346079 0.703 NM_021798
IL21R
interleukin 21 receptor
chr8_+_124264054 0.700 FAM83A
family with sequence similarity 83, member A
chrX_-_133620103 0.688 NM_021796
PLAC1
placenta-specific 1
chr7_+_74962234 0.674 NM_001099435
SPDYE5
speedy homolog E5 (Xenopus laevis)
chr7_-_104354325 0.660 LOC723809
hypothetical LOC723809
chrX_-_24241352 0.615 NM_001136233
FAM48B2
family with sequence similarity 48, member B2
chr8_+_22075112 0.610 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr12_+_108452117 0.583 UBE3B
ubiquitin protein ligase E3B
chr1_-_31117948 0.579 SDC3
syndecan 3
chr21_+_42492867 0.566 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr22_+_21079355 0.563


chr4_-_9632192 0.558 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr15_-_70385709 0.554 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr15_+_78520634 0.552 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr9_-_129752687 0.538 NM_203305
FAM102A
family with sequence similarity 102, member A
chrX_-_100015783 0.529 NM_007052
NM_013955
NOX1

NADPH oxidase 1

chr1_+_557269 0.520


chr12_+_52121699 0.512 NM_001005354
NM_018457
PRR13

proline rich 13

chr6_+_158654890 0.501


chr9_-_116196505 0.500 NM_030767
AKNA
AT-hook transcription factor
chr17_-_53335748 0.497 NM_017949
CUEDC1
CUE domain containing 1
chr1_+_26220895 0.487 EXTL1
exostoses (multiple)-like 1
chr19_+_48912053 0.486 NM_019612
IRGC
immunity-related GTPase family, cinema
chr19_+_9064854 0.473 NM_001004456
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr6_-_2580296 0.463 NM_152554
C6orf195
chromosome 6 open reading frame 195
chr1_+_559129 0.447


chr16_-_21571463 0.446 NM_005849
IGSF6
immunoglobulin superfamily, member 6
chr15_+_80741876 0.446 LOC80154
hypothetical LOC80154
chr20_+_57199469 0.441 NM_178457
ZNF831
zinc finger protein 831
chr15_+_80741827 0.439 LOC80154
hypothetical LOC80154
chr22_+_20880159 0.432 IGLV6-57
immunoglobulin lambda variable 6-57
chr7_+_44007012 0.426 NM_175064
SPDYE1
speedy homolog E1 (Xenopus laevis)
chr17_-_37022465 0.425 NM_005557
KRT16
keratin 16
chr12_+_50568010 0.424 NM_001130015
NM_182608
ANKRD33

ankyrin repeat domain 33

chr22_+_19248810 0.417 MED15
mediator complex subunit 15
chrX_+_135079461 0.411 NM_001167819
FHL1
four and a half LIM domains 1
chr20_-_31055892 0.411 NM_080675
SUN5
Sad1 and UNC84 domain containing 5
chr1_+_158387975 0.407 NM_144699
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr10_-_75352540 0.405 NM_001001791
C10orf55
chromosome 10 open reading frame 55
chr11_-_8695974 0.403 ST5
suppression of tumorigenicity 5
chr19_-_56612653 0.394 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr1_+_151596953 0.386 NM_002965
S100A9
S100 calcium binding protein A9
chr11_-_62218759 0.381 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_+_158654464 0.380 TULP4
tubby like protein 4
chr3_-_9570412 0.371 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr1_+_116744992 0.366 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr20_+_31613800 0.350 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr19_-_46504831 0.349


chr16_-_88604029 0.346 NM_024043
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr16_-_30694799 0.341


chr22_+_20880112 0.341


chr15_+_39032927 0.340 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr9_-_94226380 0.340 NM_005014
OMD
osteomodulin
chr15_-_70838703 0.337


chr2_-_113310796 0.334 NM_000576
IL1B
interleukin 1, beta
chr19_+_1401117 0.334 NM_005883
APC2
adenomatosis polyposis coli 2
chr7_-_138014329 0.330 NM_001139456
SVOPL
SVOP-like
chr19_+_1401208 0.328 APC2
adenomatosis polyposis coli 2
chr6_+_37511383 0.327


chr19_-_19234559 0.327 NM_023002
HAPLN4
hyaluronan and proteoglycan link protein 4
chr17_+_53670785 0.324 NM_001160102
NM_006151
LPO

lactoperoxidase

chr7_-_36991189 0.322 NM_001039459
ELMO1
engulfment and cell motility 1
chrX_-_13745108 0.318 GPM6B
glycoprotein M6B
chr1_-_16006779 0.315 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr10_-_116434364 0.308 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr19_-_57924946 0.308 NM_030972
ZNF611
zinc finger protein 611
chr22_+_21393107 0.305 IGLJ3
immunoglobulin lambda joining 3
chr6_+_26195426 0.305 NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
HFE








hemochromatosis








chr7_+_99743260 0.304 NM_001004351
SPDYE3
speedy homolog E3 (Xenopus laevis)
chrX_+_144716619 0.299 NM_004709
CXorf1
chromosome X open reading frame 1
chr4_-_26100986 0.295 NM_000730
CCKAR
cholecystokinin A receptor
chr1_+_159943385 0.295 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr1_+_20269239 0.290 NM_000929
PLA2G5
phospholipase A2, group V
chr15_+_80434362 0.282 UBE2Q2P2
ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr10_-_103864651 0.270 NM_003893
LDB1
LIM domain binding 1
chr3_+_187813553 0.265 AHSG
alpha-2-HS-glycoprotein
chr10_-_92671005 0.263 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_-_120155581 0.252 NM_001159352
NM_001159353
NM_032044
REG4


regenerating islet-derived family, member 4


chr17_+_71508581 0.247 NM_001258
CDK3
cyclin-dependent kinase 3
chr19_-_53950458 0.247 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chrX_-_13745134 0.246 GPM6B
glycoprotein M6B
chr15_+_60838053 0.245 TLN2
talin 2
chr10_-_73167586 0.243 NM_001168390
C10orf105
chromosome 10 open reading frame 105
chr22_+_19248733 0.243 MED15
mediator complex subunit 15
chr9_+_135994734 0.237 NM_052821
WDR5
WD repeat domain 5
chr7_-_104696678 0.235 NM_182691
SRPK2
SRSF protein kinase 2
chr6_-_33862690 0.233 NM_001143944
LEMD2
LEM domain containing 2
chr12_-_120781002 0.231 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr17_+_4283967 0.231 NM_182538
SPNS3
spinster homolog 3 (Drosophila)
chr17_+_27617307 0.227 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr6_+_32713160 0.225 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr1_+_111571803 0.224 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr10_+_69539255 0.224 NM_032578
MYPN
myopalladin
chr10_-_116434102 0.220 ABLIM1
actin binding LIM protein 1
chr11_-_16953135 0.219 RPL36A
ribosomal protein L36a
chr1_-_51660328 0.219 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr3_+_141879555 0.218 NM_152616
TRIM42
tripartite motif containing 42
chr18_-_53440005 0.212 NARS
asparaginyl-tRNA synthetase
chr6_+_135558572 0.211


chr1_-_116185215 0.210 NM_005599
NHLH2
nescient helix loop helix 2
chr13_+_28496746 0.210 NM_001033602
MTUS2
microtubule associated tumor suppressor candidate 2
chr17_+_29707583 0.209 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr10_-_79459296 0.209 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr17_+_75766875 0.206 NM_024110
CARD14
caspase recruitment domain family, member 14
chr12_-_55404530 0.205 NACA
nascent polypeptide-associated complex alpha subunit
chr15_+_40481879 0.205 NM_173088
CAPN3
calpain 3, (p94)
chr5_+_149131695 0.205 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr8_-_27171852 0.204 STMN4
stathmin-like 4
chr8_-_110730183 0.200 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr2_+_113542017 0.197 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr15_-_61913134 0.195 HERC1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr10_-_92670764 0.194 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr15_+_65217412 0.194 NM_001145103
SMAD3
SMAD family member 3
chr20_-_35318690 0.193 NM_001184731
NM_021081
GHRH

growth hormone releasing hormone

chr9_+_134927185 0.192 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr8_-_27171814 0.191 NM_030795
STMN4
stathmin-like 4
chr3_-_150533948 0.190 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr16_+_24174374 0.190 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr19_-_59368625 0.190 NM_001145303
NM_144686
TMC4

transmembrane channel-like 4

chr18_-_53440012 0.189 NARS
asparaginyl-tRNA synthetase
chr17_-_61655915 0.187 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_-_60272708 0.187 NM_138412
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr1_+_17779528 0.186 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr3_-_49701085 0.185 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr17_+_18588050 0.185 NM_031456
FBXW10
CDRT1
F-box and WD repeat domain containing 10
CMT1A duplicated region transcript 1
chr8_+_42671718 0.184 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr11_+_63060848 0.184 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr6_-_157664464 0.184 C6orf35
chromosome 6 open reading frame 35
chr1_-_159543847 0.182 MPZ
myelin protein zero
chr16_-_28457825 0.182 NM_001042483
NM_012385
NUPR1

nuclear protein, transcriptional regulator, 1

chr6_+_32003180 0.180 NM_000063
NM_001145903
C2

complement component 2

chr16_-_21571409 0.180 IGSF6
immunoglobulin superfamily, member 6
chr6_+_135558744 0.180 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr11_+_18244383 0.180 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr11_-_10487212 0.180 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr1_-_180822686 0.179 NM_021133
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr17_-_75427644 0.177 NM_003655
CBX4
chromobox homolog 4
chr17_-_77488258 0.174 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chrX_+_69314060 0.174 NM_198512
DGAT2L6
diacylglycerol O-acyltransferase 2-like 6
chr7_+_28305464 0.171 NM_182899
CREB5
cAMP responsive element binding protein 5
chr2_+_169465995 0.169 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr4_+_39874921 0.168 NM_004310
RHOH
ras homolog gene family, member H
chr9_-_76692829 0.168 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr12_+_121218218 0.167 NM_152759
LRRC43
leucine rich repeat containing 43
chr1_+_26376611 0.165 CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr19_+_60838170 0.165


chrX_+_47871546 0.163 NM_205856
SPACA5
sperm acrosome associated 5
chr9_+_94766379 0.157 FGD3
FYVE, RhoGEF and PH domain containing 3
chr17_-_15463742 0.156 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr21_-_46428788 0.156 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr11_+_4571844 0.155 NM_001005169
OR52I1
olfactory receptor, family 52, subfamily I, member 1
chr20_+_62266270 0.155 NM_004535
MYT1
myelin transcription factor 1
chr20_+_54420574 0.154 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr10_-_29963847 0.153


chr8_-_38127489 0.153 NM_000349
STAR
steroidogenic acute regulatory protein
chr21_+_29322100 0.150 USP16
ubiquitin specific peptidase 16
chr11_-_65304397 0.148 NM_138368
DKFZp761E198
DKFZp761E198 protein
chr19_+_55614006 0.147 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr1_-_205210567 0.146 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr12_-_131725848 0.146 POLE
polymerase (DNA directed), epsilon
chr18_-_53439949 0.146 NARS
asparaginyl-tRNA synthetase
chr11_-_118693021 0.146 NM_006500
MCAM
melanoma cell adhesion molecule
chr3_-_42818221 0.143


chr15_-_61913186 0.142 NM_003922
HERC1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr3_-_150422474 0.142 NM_000096
CP
ceruloplasmin (ferroxidase)
chr7_-_22828922 0.141 NM_019059
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr1_+_40612891 0.141 NM_001198978
SMAP2
small ArfGAP2
chrX_-_102828238 0.140 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chr2_+_237143118 0.139 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr7_+_129720209 0.139 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chr17_+_3326045 0.139 NM_000049
ASPA
aspartoacylase
chrX_+_55043447 0.136 NM_014481
APEX2
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr1_-_9040141 0.134 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_+_13111072 0.133 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr6_-_39180390 0.133 C6orf64
chromosome 6 open reading frame 64
chr3_+_187813405 0.133 AHSG
alpha-2-HS-glycoprotein
chr15_-_64108718 0.133


chr19_-_61876057 0.132 NM_001005850
ZNF835
zinc finger protein 835
chrX_-_15198509 0.132 NM_001168531
ASB9
ankyrin repeat and SOCS box containing 9
chr1_+_203106600 0.131 NFASC
neurofascin
chr19_-_51889002 0.131 PRKD2
protein kinase D2
chr1_+_234748187 0.131 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr1_-_151549790 0.130 NM_052891
PGLYRP3
peptidoglycan recognition protein 3
chr1_-_6448737 0.129 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chrX_-_13744933 0.129 GPM6B
glycoprotein M6B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.43 4.42e-05 GO:0006955 immune response
1.90 2.21e-03 GO:0002376 immune system process
1.62 2.95e-03 GO:0042221 response to chemical stimulus
1.95 1.18e-02 GO:0009605 response to external stimulus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.63 3.29e-03 GO:0001871 pattern binding
3.63 3.29e-03 GO:0030247 polysaccharide binding
3.68 5.31e-03 GO:0005539 glycosaminoglycan binding
3.89 2.19e-02 GO:0008201 heparin binding