Motif ID: PAX5.p2

Z-value: 2.383


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37024358-0.185.1e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_88506320 3.879 NM_004329
 BMPR1A
bone morphogenetic protein receptor, type IA
chr10_+_111757867 3.572 ADD3
adducin 3 (gamma)
chr10_+_111757675 3.291 NM_001121
NM_016824
 ADD3

adducin 3 (gamma)

chr18_+_9126742 3.045 NM_001083625
NM_015208
 ANKRD12

ankyrin repeat domain 12

chr2_+_233270286 2.930 GIGYF2
GRB10 interacting GYF protein 2
chr6_+_12120709 2.813 NM_002114
 HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_113734997 2.696 NM_001142782
NM_152900
 MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr8_+_26296439 2.452 NM_004331
 BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr2_+_54536780 2.344 NM_003128
 SPTBN1
spectrin, beta, non-erythrocytic 1
chr18_+_58341637 2.265 NM_017742
 ZCCHC2
zinc finger, CCHC domain containing 2
chr6_+_160068475 2.256 WTAP
Wilms tumor 1 associated protein
chr2_+_233270275 2.250 GIGYF2
GRB10 interacting GYF protein 2
chr1_-_15723363 2.244 NM_001229
NM_032996
 CASP9

caspase 9, apoptosis-related cysteine peptidase

chr2_+_233270241 2.164 NM_001103146
NM_001103147
NM_001103148
NM_015575
 GIGYF2



GRB10 interacting GYF protein 2



chr9_+_96807107 2.162 C9orf3
chromosome 9 open reading frame 3
chr14_+_59785739 2.108 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_70459686 2.082 SRSF11
serine/arginine-rich splicing factor 11
chr1_+_86943074 2.074 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr9_+_114289178 2.065 KIAA1958
KIAA1958
chr13_+_34414390 2.034 NM_015678
 NBEA
neurobeachin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 79 entries
enrichment   p-value GO term description
1.63 3.48e-03 GO:0016311 dephosphorylation
1.62 1.36e-02 GO:0006470 protein dephosphorylation
1.49 6.30e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.40 1.48e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.36 1.06e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.36 3.13e-02 GO:0044419 interspecies interaction between organisms
1.34 1.72e-06 GO:0046907 intracellular transport
1.34 7.97e-06 GO:0016192 vesicle-mediated transport
1.30 3.23e-05 GO:0045184 establishment of protein localization
1.30 2.83e-02 GO:0034613 cellular protein localization
1.29 7.38e-05 GO:0015031 protein transport
1.29 4.58e-02 GO:0070727 cellular macromolecule localization
1.27 9.20e-05 GO:0032268 regulation of cellular protein metabolic process
1.26 4.85e-06 GO:0051641 cellular localization
1.26 3.95e-05 GO:0051246 regulation of protein metabolic process
1.26 5.20e-05 GO:0051649 establishment of localization in cell
1.26 1.34e-04 GO:0008104 protein localization
1.25 3.32e-06 GO:0009966 regulation of signal transduction
1.25 7.79e-03 GO:0008219 cell death
1.24 3.78e-04 GO:0044248 cellular catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 51 entries
enrichment   p-value GO term description
1.68 1.33e-04 GO:0031301 integral to organelle membrane
1.65 3.11e-02 GO:0042470 melanosome
1.65 3.11e-02 GO:0048770 pigment granule
1.54 4.02e-03 GO:0031300 intrinsic to organelle membrane
1.54 9.62e-03 GO:0005769 early endosome
1.51 2.00e-02 GO:0005912 adherens junction
1.48 4.26e-04 GO:0005635 nuclear envelope
1.48 2.52e-02 GO:0070161 anchoring junction
1.44 1.82e-02 GO:0005911 cell-cell junction
1.42 4.87e-02 GO:0030135 coated vesicle
1.36 5.63e-03 GO:0005815 microtubule organizing center
1.36 1.78e-02 GO:0015629 actin cytoskeleton
1.30 1.09e-04 GO:0015630 microtubule cytoskeleton
1.30 8.13e-03 GO:0000139 Golgi membrane
1.28 3.71e-16 GO:0005829 cytosol
1.28 2.76e-03 GO:0044431 Golgi apparatus part
1.28 4.74e-02 GO:0005768 endosome
1.27 7.16e-03 GO:0030054 cell junction
1.26 7.84e-10 GO:0012505 endomembrane system
1.26 3.28e-05 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.72 1.02e-02 GO:0035257 nuclear hormone receptor binding
1.66 1.94e-02 GO:0004725 protein tyrosine phosphatase activity
1.64 2.82e-02 GO:0051427 hormone receptor binding
1.56 4.17e-02 GO:0035091 phosphatidylinositol binding
1.53 8.74e-03 GO:0004721 phosphoprotein phosphatase activity
1.38 1.08e-03 GO:0000988 protein binding transcription factor activity
1.38 1.08e-03 GO:0000989 transcription factor binding transcription factor activity
1.38 1.22e-02 GO:0008134 transcription factor binding
1.37 1.50e-03 GO:0003712 transcription cofactor activity
1.34 2.98e-03 GO:0019904 protein domain specific binding
1.32 4.32e-03 GO:0030695 GTPase regulator activity
1.31 1.48e-02 GO:0004674 protein serine/threonine kinase activity
1.30 1.29e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.28 4.58e-04 GO:0019899 enzyme binding
1.25 4.44e-03 GO:0042802 identical protein binding
1.22 1.09e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 2.23e-27 GO:0005515 protein binding
1.16 2.01e-04 GO:0000166 nucleotide binding
1.15 4.21e-03 GO:0032553 ribonucleotide binding
1.15 4.21e-03 GO:0032555 purine ribonucleotide binding