Motif ID: PAX5.p2

Z-value: 2.383


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37024358-0.185.1e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_88506320 3.879 NM_004329
BMPR1A
bone morphogenetic protein receptor, type IA
chr10_+_111757867 3.572 ADD3
adducin 3 (gamma)
chr10_+_111757675 3.291 NM_001121
NM_016824
ADD3

adducin 3 (gamma)

chr18_+_9126742 3.045 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr2_+_233270286 2.930 GIGYF2
GRB10 interacting GYF protein 2
chr6_+_12120709 2.813 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_113734997 2.696 NM_001142782
NM_152900
MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr8_+_26296439 2.452 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr2_+_54536780 2.344 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr18_+_58341637 2.265 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr6_+_160068475 2.256 WTAP
Wilms tumor 1 associated protein
chr2_+_233270275 2.250 GIGYF2
GRB10 interacting GYF protein 2
chr1_-_15723363 2.244 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr2_+_233270241 2.164 NM_001103146
NM_001103147
NM_001103148
NM_015575
GIGYF2



GRB10 interacting GYF protein 2



chr9_+_96807107 2.162 C9orf3
chromosome 9 open reading frame 3
chr14_+_59785739 2.108 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_70459686 2.082 SRSF11
serine/arginine-rich splicing factor 11
chr1_+_86943074 2.074 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr9_+_114289178 2.065 KIAA1958
KIAA1958
chr13_+_34414390 2.034 NM_015678
NBEA
neurobeachin
chr8_-_13035102 2.031 NM_006094
DLC1
deleted in liver cancer 1
chr14_+_59785703 2.018 NM_021003
NM_177951
PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr14_+_59786047 1.997 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_86943103 1.969 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr13_+_97426713 1.962 IPO5
importin 5
chr10_+_35665614 1.951 NM_145012
CCNY
cyclin Y
chr3_+_173240983 1.929 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr20_+_1154763 1.903 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr15_+_54998144 1.870 TCF12
transcription factor 12
chr8_+_136538739 1.849 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr2_-_36384 1.841 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr10_+_171410 1.821 ZMYND11
zinc finger, MYND-type containing 11
chr6_+_64403631 1.775 PHF3
PHD finger protein 3
chr8_-_13034873 1.754 DLC1
deleted in liver cancer 1
chr9_+_90193058 1.746 NM_006717
SPIN1
spindlin 1
chr2_+_235525355 1.733 NM_014521
SH3BP4
SH3-domain binding protein 4
chr6_+_160068531 1.731 WTAP
Wilms tumor 1 associated protein
chr3_+_133923758 1.729 NCRNA00119
non-protein coding RNA 119
chr11_+_34894688 1.714 PDHX
pyruvate dehydrogenase complex, component X
chr16_-_3225360 1.697 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr6_+_160068553 1.686 WTAP
Wilms tumor 1 associated protein
chr6_+_117910472 1.652 NM_173674
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr6_+_160068598 1.644 NM_152857
WTAP
Wilms tumor 1 associated protein
chr1_+_86942874 1.643 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr5_+_122138677 1.637 SNX2
sorting nexin 2
chr5_+_122138661 1.634 SNX2
sorting nexin 2
chr2_+_108517239 1.627 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_85051687 1.616 NM_020122
KCMF1
potassium channel modulatory factor 1
chr2_+_8739563 1.599 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr2_+_238265519 1.586 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr2_+_108517356 1.578 LIMS1
LIM and senescent cell antigen-like domains 1
chr13_+_26029879 1.549 WASF3
WAS protein family, member 3
chr11_+_12652427 1.547 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_-_99906944 1.538 NM_006281
STK3
serine/threonine kinase 3
chr5_+_122138636 1.537 NM_003100
SNX2
sorting nexin 2
chr6_+_64403668 1.529 PHF3
PHD finger protein 3
chr1_+_70459592 1.522 SRSF11
serine/arginine-rich splicing factor 11
chr4_+_99401543 1.510 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr14_-_38971370 1.509 NM_203301
FBXO33
F-box protein 33
chr15_+_97923737 1.493 MEF2A
myocyte enhancer factor 2A
chr16_+_68157611 1.473 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr6_-_109911125 1.469 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr2_+_238265617 1.467 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr2_+_233927892 1.460 DGKD
diacylglycerol kinase, delta 130kDa
chr6_+_64403936 1.457 PHF3
PHD finger protein 3
chr3_+_197951203 1.441 PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr14_+_59785723 1.440 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_+_11819364 1.439 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr6_+_163755658 1.438 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr14_-_91372365 1.434 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr2_-_215382537 1.427 NM_000465
BARD1
BRCA1 associated RING domain 1
chr11_-_34894407 1.424 NM_015957
APIP
APAF1 interacting protein
chr2_+_62276764 1.415 NM_006577
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr20_-_51644187 1.413 ZNF217
zinc finger protein 217
chr15_-_54997964 1.399 LOC145783
hypothetical LOC145783
chr18_+_7557313 1.388 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr12_+_970613 1.374 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr20_-_48980858 1.364 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr8_+_17058170 1.361 NM_016353
ZDHHC2
zinc finger, DHHC-type containing 2
chr15_+_54998264 1.353 TCF12
transcription factor 12
chr3_+_197951121 1.348 NM_002577
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr6_+_132170847 1.346 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr20_+_61841662 1.333 SLC2A4RG
SLC2A4 regulator
chr2_+_85051942 1.322 KCMF1
potassium channel modulatory factor 1
chr2_+_159533329 1.317 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr2_+_10009242 1.316 NM_198182
GRHL1
grainyhead-like 1 (Drosophila)
chr11_+_101485946 1.306 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr3_+_58452560 1.296 NM_001128214
KCTD6
potassium channel tetramerisation domain containing 6
chr1_+_24944554 1.288 CLIC4
chloride intracellular channel 4
chr5_+_126881207 1.286 NM_130809
PRRC1
proline-rich coiled-coil 1
chr2_+_200879737 1.283 SPATS2L
spermatogenesis associated, serine-rich 2-like
chr3_+_43303005 1.266 NM_001100594
NM_017719
SNRK

SNF related kinase

chr5_-_114660139 1.259 NM_001040440
CCDC112
coiled-coil domain containing 112
chr3_+_23961739 1.255 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr17_+_11864841 1.240 NM_003010
MAP2K4
mitogen-activated protein kinase kinase 4
chr6_+_160068544 1.235 WTAP
Wilms tumor 1 associated protein
chr6_+_163755788 1.218 QKI
quaking homolog, KH domain RNA binding (mouse)
chr1_+_208178198 1.216 SYT14
synaptotagmin XIV
chr6_-_109911015 1.212 ZBTB24
zinc finger and BTB domain containing 24
chr15_+_67239853 1.209 NM_015554
GLCE
glucuronic acid epimerase
chr2_+_198089036 1.198 MOBKL3
MOB1, Mps One Binder kinase activator-like 3 (yeast)
chr18_+_11971443 1.196 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr1_+_86942810 1.196 NM_016009
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr6_+_158164269 1.192 NM_016224
SNX9
sorting nexin 9
chr9_+_130354490 1.189 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr3_-_133923992 1.184 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr20_+_32045214 1.181 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr20_+_61841553 1.176 NM_020062
SLC2A4RG
SLC2A4 regulator
chr1_+_181259317 1.174


chr1_+_24158898 1.169 PNRC2
proline-rich nuclear receptor coactivator 2
chr17_+_63609317 1.154 LOC100499466
hypothetical LOC100499466
chr2_+_233927880 1.151 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr16_-_11588525 1.147 LITAF
lipopolysaccharide-induced TNF factor
chr18_+_53862744 1.146 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_+_38722593 1.145 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr14_+_31616196 1.145 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr16_+_51722285 1.138 CHD9
chromodomain helicase DNA binding protein 9
chr8_+_17058377 1.138 ZDHHC2
zinc finger, DHHC-type containing 2
chr18_+_11971421 1.131 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr16_+_68157370 1.128 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr13_+_27094029 1.125 POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr2_+_97142959 1.123 NM_001164315
ANKRD36
ankyrin repeat domain 36
chr15_+_54998181 1.118 TCF12
transcription factor 12
chr2_-_106869949 1.118 NM_001142352
NM_032528
ST6GAL2

ST6 beta-galactosamide alpha-2,6-sialyltranferase 2

chr1_+_171713104 1.115 NM_004905
PRDX6
peroxiredoxin 6
chr3_+_32255158 1.114 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr2_+_198088997 1.112 NM_001100819
NM_015387
MOBKL3

MOB1, Mps One Binder kinase activator-like 3 (yeast)

chr14_+_56927014 1.109 NM_001011713
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr15_+_73923047 1.108 UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr6_+_163755773 1.107 QKI
quaking homolog, KH domain RNA binding (mouse)
chr2_+_171494026 1.107 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr17_+_64020159 1.100 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr12_+_68150332 1.100 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr7_+_26207806 1.094 NM_016587
CBX3
chromobox homolog 3
chr6_+_147567200 1.091 NM_001127715
NM_139244
STXBP5

syntaxin binding protein 5 (tomosyn)

chr2_+_171493870 1.091 NM_015530
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr5_-_180162319 1.089 MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr14_+_93710401 1.082 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr2_+_86521999 1.079 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr11_+_34894252 1.079 NM_001135024
NM_001166158
NM_003477
PDHX


pyruvate dehydrogenase complex, component X


chr6_+_64403685 1.077 PHF3
PHD finger protein 3
chr20_+_8060762 1.075 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr14_+_56927066 1.073 NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_+_219283928 1.067 TTLL4
tubulin tyrosine ligase-like family, member 4
chr15_+_54998115 1.067 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr19_+_61742111 1.065 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr13_-_105985313 1.057 NM_004093
EFNB2
ephrin-B2
chr2_+_203208456 1.052 FAM117B
family with sequence similarity 117, member B
chr13_-_109236897 1.050 NM_003749
IRS2
insulin receptor substrate 2
chr9_-_95253576 1.050 FAM120AOS
family with sequence similarity 120A opposite strand
chr6_+_160068135 1.049 NM_004906
NM_152858
WTAP

Wilms tumor 1 associated protein

chr3_-_133923906 1.048 NM_153240
NPHP3
nephronophthisis 3 (adolescent)
chr4_+_144325533 1.042 USP38
ubiquitin specific peptidase 38
chr14_-_55116544 1.039 C14orf33
chromosome 14 open reading frame 33
chr6_+_158164294 1.039 SNX9
sorting nexin 9
chr5_+_102622305 1.038 NM_033211
C5orf30
chromosome 5 open reading frame 30
chr12_+_6907646 1.034 NM_001940
ATN1
atrophin 1
chr20_+_254205 1.031 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr7_+_77004267 1.029 PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr18_+_11971457 1.026 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr20_+_56900116 1.026 NM_001077488
GNAS
GNAS complex locus
chr12_+_123023521 1.022 NM_152437
ZNF664
zinc finger protein 664
chr17_+_32924049 1.020 NM_007026
DUSP14
dual specificity phosphatase 14
chr3_+_182113125 1.017 FXR1
fragile X mental retardation, autosomal homolog 1
chr11_+_86426518 1.015 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr20_+_52525538 1.014 NM_018431
DOK5
docking protein 5
chr18_+_53862888 1.012 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr8_+_42871319 1.011


chr12_+_131134799 1.008 EP400NL
EP400 N-terminal like
chr3_-_125085834 1.004 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr4_+_86615275 0.997 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr6_+_237033 0.994 NM_020185
DUSP22
dual specificity phosphatase 22
chr20_+_42947764 0.994 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr7_-_122961808 0.994 NM_178827
IQUB
IQ motif and ubiquitin domain containing
chr4_+_3046034 0.993 NM_002111
HTT
huntingtin
chr13_+_26029799 0.993 NM_006646
WASF3
WAS protein family, member 3
chr15_+_65145215 0.990 SMAD3
SMAD family member 3
chr6_+_89847183 0.990 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_4721825 0.989 CDYL
chromodomain protein, Y-like
chr12_+_131134741 0.984 EP400NL
EP400 N-terminal like
chr7_+_26207854 0.981 CBX3
chromobox homolog 3
chr9_+_100907213 0.981 TGFBR1
transforming growth factor, beta receptor 1
chr12_-_131415854 0.978 NM_001122636
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr17_+_32924090 0.976 DUSP14
dual specificity phosphatase 14
chr9_+_100907292 0.972


chr2_-_16710551 0.971 NM_030797
FAM49A
family with sequence similarity 49, member A
chr6_-_4080700 0.969 NM_001166010
NM_006117
NM_206836
PECI


peroxisomal D3,D2-enoyl-CoA isomerase


chr1_-_22342001 0.969 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr7_+_130663134 0.966 NM_013255
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr4_+_110574420 0.966 SEC24B
SEC24 family, member B (S. cerevisiae)
chr2_+_9264360 0.965 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr11_+_67836575 0.964 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr11_+_129190942 0.964 NM_138788
TMEM45B
transmembrane protein 45B
chr7_+_77004686 0.963 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr5_+_72179685 0.962 NM_153188
TNPO1
transportin 1
chr12_+_19173669 0.959 NM_001143821
NM_001190860
NM_019012
PLEKHA5


pleckstrin homology domain containing, family A member 5


chr21_+_46473494 0.957 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr12_+_109203526 0.955 ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr11_+_109469296 0.954 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_24158887 0.954 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 6.84e-17 GO:0009987 cellular process
1.14 1.63e-14 GO:0044237 cellular metabolic process
1.11 1.76e-11 GO:0008152 metabolic process
1.12 1.78e-11 GO:0044238 primary metabolic process
1.16 2.40e-11 GO:0044260 cellular macromolecule metabolic process
1.11 3.39e-11 GO:0050794 regulation of cellular process
1.11 4.14e-10 GO:0050789 regulation of biological process
1.10 8.49e-10 GO:0065007 biological regulation
1.16 4.35e-09 GO:0019222 regulation of metabolic process
1.20 2.07e-08 GO:0044267 cellular protein metabolic process
1.13 2.34e-08 GO:0043170 macromolecule metabolic process
1.16 4.16e-08 GO:0031323 regulation of cellular metabolic process
1.17 5.25e-08 GO:0060255 regulation of macromolecule metabolic process
1.23 6.06e-08 GO:0006464 protein modification process
1.16 9.77e-08 GO:0080090 regulation of primary metabolic process
1.22 4.09e-07 GO:0043412 macromolecule modification
1.20 1.15e-06 GO:0048523 negative regulation of cellular process
1.15 1.40e-06 GO:0016043 cellular component organization
1.34 1.72e-06 GO:0046907 intracellular transport
1.15 1.79e-06 GO:0071840 cellular component organization or biogenesis
1.25 3.32e-06 GO:0009966 regulation of signal transduction
1.26 4.85e-06 GO:0051641 cellular localization
1.16 6.85e-06 GO:0019538 protein metabolic process
1.34 7.97e-06 GO:0016192 vesicle-mediated transport
1.36 1.06e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.40 1.48e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.30 3.23e-05 GO:0045184 establishment of protein localization
1.26 3.95e-05 GO:0051246 regulation of protein metabolic process
1.14 4.19e-05 GO:0051179 localization
1.26 5.20e-05 GO:0051649 establishment of localization in cell
1.21 5.83e-05 GO:0023051 regulation of signaling
1.17 7.20e-05 GO:0048522 positive regulation of cellular process
1.29 7.38e-05 GO:0015031 protein transport
1.17 7.70e-05 GO:0048519 negative regulation of biological process
1.27 9.20e-05 GO:0032268 regulation of cellular protein metabolic process
1.15 1.26e-04 GO:0048518 positive regulation of biological process
1.26 1.34e-04 GO:0008104 protein localization
1.23 1.91e-04 GO:0033036 macromolecule localization
1.15 2.00e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.15 2.18e-04 GO:0071842 cellular component organization at cellular level
1.15 3.15e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 3.78e-04 GO:0044248 cellular catabolic process
1.13 4.50e-04 GO:0034641 cellular nitrogen compound metabolic process
1.19 5.99e-04 GO:0006996 organelle organization
1.13 7.82e-04 GO:0006807 nitrogen compound metabolic process
1.23 1.07e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.15 1.23e-03 GO:0010468 regulation of gene expression
1.14 1.61e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.14 2.24e-03 GO:0009058 biosynthetic process
1.20 2.51e-03 GO:0065009 regulation of molecular function
1.14 3.45e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63 3.48e-03 GO:0016311 dephosphorylation
1.10 4.29e-03 GO:0051716 cellular response to stimulus
1.14 4.61e-03 GO:0044249 cellular biosynthetic process
1.23 5.21e-03 GO:0006793 phosphorus metabolic process
1.23 5.21e-03 GO:0006796 phosphate metabolic process
1.20 5.86e-03 GO:0009893 positive regulation of metabolic process
1.49 6.30e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.25 7.79e-03 GO:0008219 cell death
1.22 8.39e-03 GO:0007049 cell cycle
1.14 8.70e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.24 9.12e-03 GO:0016265 death
1.12 9.13e-03 GO:0051234 establishment of localization
1.19 1.01e-02 GO:0009056 catabolic process
1.62 1.36e-02 GO:0006470 protein dephosphorylation
1.20 1.46e-02 GO:0031325 positive regulation of cellular metabolic process
1.22 1.95e-02 GO:0009892 negative regulation of metabolic process
1.23 2.14e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.12 2.21e-02 GO:0006810 transport
1.13 2.58e-02 GO:0031326 regulation of cellular biosynthetic process
1.13 2.64e-02 GO:0009889 regulation of biosynthetic process
1.30 2.83e-02 GO:0034613 cellular protein localization
1.15 3.10e-02 GO:0048583 regulation of response to stimulus
1.24 3.11e-02 GO:0031399 regulation of protein modification process
1.36 3.13e-02 GO:0044419 interspecies interaction between organisms
1.13 3.14e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.29 4.58e-02 GO:0070727 cellular macromolecule localization
1.11 4.87e-02 GO:0007165 signal transduction
1.22 4.94e-02 GO:0031324 negative regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 8.07e-42 GO:0005622 intracellular
1.12 5.78e-41 GO:0044424 intracellular part
1.16 5.21e-36 GO:0005737 cytoplasm
1.12 1.90e-29 GO:0043229 intracellular organelle
1.12 2.89e-29 GO:0043226 organelle
1.14 1.11e-28 GO:0043231 intracellular membrane-bounded organelle
1.13 1.56e-28 GO:0043227 membrane-bounded organelle
1.18 1.67e-24 GO:0044444 cytoplasmic part
1.28 3.71e-16 GO:0005829 cytosol
1.15 3.63e-15 GO:0005634 nucleus
1.15 8.17e-15 GO:0044446 intracellular organelle part
1.14 1.11e-14 GO:0044422 organelle part
1.04 2.86e-12 GO:0044464 cell part
1.04 3.21e-12 GO:0005623 cell
1.26 7.84e-10 GO:0012505 endomembrane system
1.20 1.61e-07 GO:0044428 nuclear part
1.19 7.10e-07 GO:0031090 organelle membrane
1.18 8.38e-07 GO:0070013 intracellular organelle lumen
1.18 1.76e-06 GO:0043233 organelle lumen
1.17 3.19e-06 GO:0031974 membrane-enclosed lumen
1.15 9.97e-06 GO:0043234 protein complex
1.26 3.28e-05 GO:0005794 Golgi apparatus
1.18 4.93e-05 GO:0031981 nuclear lumen
1.30 1.09e-04 GO:0015630 microtubule cytoskeleton
1.68 1.33e-04 GO:0031301 integral to organelle membrane
1.48 4.26e-04 GO:0005635 nuclear envelope
1.22 7.09e-04 GO:0005783 endoplasmic reticulum
1.19 1.28e-03 GO:0005654 nucleoplasm
1.26 2.28e-03 GO:0044451 nucleoplasm part
1.28 2.76e-03 GO:0044431 Golgi apparatus part
1.54 4.02e-03 GO:0031300 intrinsic to organelle membrane
1.36 5.63e-03 GO:0005815 microtubule organizing center
1.10 5.69e-03 GO:0032991 macromolecular complex
1.27 7.16e-03 GO:0030054 cell junction
1.23 8.03e-03 GO:0031410 cytoplasmic vesicle
1.30 8.13e-03 GO:0000139 Golgi membrane
1.54 9.62e-03 GO:0005769 early endosome
1.23 9.63e-03 GO:0031982 vesicle
1.36 1.78e-02 GO:0015629 actin cytoskeleton
1.44 1.82e-02 GO:0005911 cell-cell junction
1.51 2.00e-02 GO:0005912 adherens junction
1.48 2.52e-02 GO:0070161 anchoring junction
1.22 2.91e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.65 3.11e-02 GO:0042470 melanosome
1.65 3.11e-02 GO:0048770 pigment granule
1.15 3.13e-02 GO:0005856 cytoskeleton
1.22 3.21e-02 GO:0031967 organelle envelope
1.22 3.49e-02 GO:0031975 envelope
1.22 3.56e-02 GO:0031988 membrane-bounded vesicle
1.28 4.74e-02 GO:0005768 endosome
1.42 4.87e-02 GO:0030135 coated vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.23e-27 GO:0005515 protein binding
1.08 1.09e-20 GO:0005488 binding
1.10 2.26e-05 GO:0003824 catalytic activity
1.16 2.01e-04 GO:0000166 nucleotide binding
1.28 4.58e-04 GO:0019899 enzyme binding
1.38 1.08e-03 GO:0000988 protein binding transcription factor activity
1.38 1.08e-03 GO:0000989 transcription factor binding transcription factor activity
1.37 1.50e-03 GO:0003712 transcription cofactor activity
1.34 2.98e-03 GO:0019904 protein domain specific binding
1.15 4.21e-03 GO:0032553 ribonucleotide binding
1.15 4.21e-03 GO:0032555 purine ribonucleotide binding
1.32 4.32e-03 GO:0030695 GTPase regulator activity
1.25 4.44e-03 GO:0042802 identical protein binding
1.15 5.97e-03 GO:0017076 purine nucleotide binding
1.53 8.74e-03 GO:0004721 phosphoprotein phosphatase activity
1.15 8.98e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.72 1.02e-02 GO:0035257 nuclear hormone receptor binding
1.22 1.09e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.38 1.22e-02 GO:0008134 transcription factor binding
1.30 1.29e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.15 1.45e-02 GO:0016740 transferase activity
1.31 1.48e-02 GO:0004674 protein serine/threonine kinase activity
1.66 1.94e-02 GO:0004725 protein tyrosine phosphatase activity
1.64 2.82e-02 GO:0051427 hormone receptor binding
1.56 4.17e-02 GO:0035091 phosphatidylinositol binding
1.15 4.56e-02 GO:0032559 adenyl ribonucleotide binding