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Motif ID: SRF.p3

Z-value: 1.822

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_137829065	17.380		EGR1	early growth response 1
chr5_+_137829077	15.395	NM_001964	EGR1	early growth response 1
chr17_+_30498948	4.316	NM_001033576 NM_173167	UNC45B	unc-45 homolog B (C. elegans)
chr10_-_64246129	3.720	NM_000399 NM_001136177 NM_001136179	EGR2	early growth response 2
chr20_+_34603290	3.599	NM_006097 NM_181526	MYL9	myosin, light chain 9, regulatory
chr12_+_50731457	3.181	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr20_+_34603311	3.057		MYL9	myosin, light chain 9, regulatory
chr12_+_52713098	2.852	NM_018953	HOXC5	homeobox C5
chr10_-_64246080	2.460		EGR2	early growth response 2
chr19_+_2427122	2.435	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr10_+_112247614	2.427	NM_004419	DUSP5	dual specificity phosphatase 5
chr9_+_91409746	2.175	NM_006705	GADD45G	growth arrest and DNA-damage-inducible, gamma
chr1_+_6226838	2.100	NM_001024598	HES3	hairy and enhancer of split 3 (Drosophila)
chr3_-_46879883	2.073	NM_000258	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr22_+_29810981	1.973		SMTN	smoothelin
chr2_+_73973600	1.964	NM_001615	ACTG2	actin, gamma 2, smooth muscle, enteric
chr2_-_30883775	1.889	NM_144575	CAPN13	calpain 13
chr20_-_21442663	1.788	NM_002509	NKX2-2	NK2 homeobox 2
chr2_+_73973640	1.764		ACTG2	actin, gamma 2, smooth muscle, enteric
chr19_+_12995782	1.723		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_116575249	1.619	NM_001001522 NM_003186	TAGLN	transgelin
chr19_+_50663089	1.594	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr9_+_36126710	1.412	NM_022343	GLIPR2	GLI pathogenesis-related 2
chr9_+_36126667	1.314		GLIPR2	GLI pathogenesis-related 2
chr19_+_53650577	1.302	NM_013348	KCNJ14	potassium inwardly-rectifying channel, subfamily J, member 14
chr14_+_73775927	1.279	NM_182894	VSX2	visual system homeobox 2
chr20_+_4650499	1.188	NM_012409	PRND	prion protein 2 (dublet)
chr9_+_139892049	1.096	NM_000718	CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr11_+_74950893	1.086		SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_-_47330797	1.035	NM_000256	MYBPC3	myosin binding protein C, cardiac
chr16_-_11282595	0.969	NM_002761	PRM1	protamine 1
chr5_+_60663842	0.941	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr15_+_94670160	0.938	NM_001145155	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr13_-_45640679	0.935		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_87536106	0.918		NCRNA00152	non-protein coding RNA 152
chr17_+_3326045	0.914	NM_000049	ASPA	aspartoacylase
chr14_-_93512818	0.905		ASB2	ankyrin repeat and SOCS box containing 2
chr2_-_160765008	0.892		ITGB6	integrin, beta 6
chr11_+_65945050	0.854	NM_178864	NPAS4	neuronal PAS domain protein 4
chr1_-_11830328	0.802	NM_006172	NPPA	natriuretic peptide A
chr2_-_128149112	0.800	NM_001136037 NM_001161403	LIMS2	LIM and senescent cell antigen-like domains 2
chr6_-_159386007	0.796	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr17_-_44026042	0.769	NM_002147	HOXB5	homeobox B5
chr14_+_104338423	0.753		ZBTB42	zinc finger and BTB domain containing 42
chr10_+_75427853	0.751	NM_003373 NM_014000	VCL	vinculin
chr3_-_124821868	0.744		MYLK	myosin light chain kinase
chr13_-_98757634	0.731	NM_004951	GPR183	G protein-coupled receptor 183
chr1_-_227636462	0.724	NM_001100	ACTA1	actin, alpha 1, skeletal muscle
chr15_+_43193810	0.716	NM_207581	DUOXA2	dual oxidase maturation factor 2
chr9_-_78710698	0.714	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr17_-_44026321	0.705		HOXB5	homeobox B5
chr2_-_73373956	0.698	NM_001965	EGR4	early growth response 4
chr6_-_109882116	0.683		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr15_-_63147350	0.674	NM_016563	RASL12	RAS-like, family 12
chr18_-_42804531	0.671	NM_145653	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)
chr17_+_39990124	0.652	NM_001466	FZD2	frizzled homolog 2 (Drosophila)
chr19_+_977582	0.616		CNN2	calponin 2
chr10_-_131652364	0.613		EBF3	early B-cell factor 3
chr3_-_71376919	0.601		FOXP1	forkhead box P1
chr11_-_75599433	0.599		WNT11	wingless-type MMTV integration site family, member 11
chr3_+_150675117	0.597	NM_004617	TM4SF4	transmembrane 4 L six family member 4
chr16_-_66535457	0.595	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr18_-_42804291	0.593	NM_001100817	TCEB3C TCEB3CL	transcription elongation factor B polypeptide 3C (elongin A3) transcription elongation factor B polypeptide 3C-like
chr4_+_109033868	0.593	NM_001136257 NM_152621	SGMS2	sphingomyelin synthase 2
chr4_+_6746466	0.559	NM_005980	S100P	S100 calcium binding protein P
chr1_-_2451543	0.559	NM_001010926	HES5	hairy and enhancer of split 5 (Drosophila)
chr12_+_4253143	0.551	NM_001759	CCND2	cyclin D2
chr7_+_142788480	0.551	NM_001010972 NM_003461	ZYX	zyxin
chr1_+_179324458	0.549		IER5	immediate early response 5
chr22_+_28206180	0.543	NM_021076	NEFH	neurofilament, heavy polypeptide
chr14_-_93512647	0.531		ASB2	ankyrin repeat and SOCS box containing 2
chr18_+_75388522	0.530		NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_-_88468368	0.529		AKIRIN2	akirin 2
chr19_+_40541327	0.528	NM_005304	FFAR3	free fatty acid receptor 3
chr7_+_142788521	0.515		ZYX	zyxin
chr19_+_12996368	0.511		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr14_-_104507862	0.498		AHNAK2	AHNAK nucleoprotein 2
chr10_+_88418243	0.493	NM_001080116 NM_001080114 NM_001080115 NM_001171611 NM_007078	LDB3	LIM domain binding 3
chr15_-_43193637	0.491	NM_014080	DUOX2	dual oxidase 2
chr7_+_142788569	0.484		ZYX	zyxin
chr19_+_977608	0.479		CNN2	calponin 2
chr14_+_74815233	0.476	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr20_+_60558104	0.474	NM_178463	C20orf166	chromosome 20 open reading frame 166
chr7_+_113842284	0.470	NM_001172766 NM_014491 NM_148898 NM_148900	FOXP2	forkhead box P2
chr19_+_59064795	0.468		MYADM	myeloid-associated differentiation marker
chr5_+_169749068	0.465
chr5_+_176807931	0.457	NM_001174102	PRR7	proline rich 7 (synaptic)
chr1_-_16217025	0.454		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr19_+_977555	0.449		CNN2	calponin 2
chr6_+_167445284	0.442	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr7_+_142788517	0.435		ZYX	zyxin
chr18_-_3209846	0.434		MYOM1	myomesin 1, 185kDa
chr17_-_77094426	0.432		ACTG1	actin, gamma 1
chr19_+_54068300	0.430		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr7_+_142788566	0.429		ZYX	zyxin
chr10_+_6226884	0.420		PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr10_+_114033403	0.420	NM_058222	TECTB	tectorin beta
chr11_-_2118743	0.416		IGF2	insulin-like growth factor 2 (somatomedin A)
chr2_+_26768894	0.410	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr10_+_6226909	0.410		PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_+_151655623	0.402	NM_176823	S100A7A	S100 calcium binding protein A7A
chr3_+_9809776	0.402	NM_001198780	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa
chr19_+_977624	0.399		CNN2	calponin 2
chr19_+_977601	0.392		CNN2	calponin 2
chr1_-_31618405	0.391	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr20_+_32610161	0.387	NM_032514	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha
chr22_+_36412277	0.379	NM_024313	NOL12	nucleolar protein 12
chr17_-_46296376	0.379	NM_005749	TOB1	transducer of ERBB2, 1
chrX_+_99726445	0.376	NM_022144	TNMD	tenomodulin
chr14_-_105163301	0.372		IGHG4	immunoglobulin heavy constant gamma 4 (G4m marker)
chr12_-_46405477	0.371	NM_001172439 NM_001172440 NM_006025	ENDOU	endonuclease, polyU-specific
chr15_-_43193614	0.368		DUOX2	dual oxidase 2
chr19_+_977627	0.364		CNN2	calponin 2
chr7_+_142788730	0.361		ZYX	zyxin
chr22_+_38246509	0.359	NM_001675 NM_182810	ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)
chr17_+_29707583	0.356	NM_005408	CCL13	chemokine (C-C motif) ligand 13
chr10_-_29963847	0.352
chr19_-_50912429	0.351
chr19_+_59064471	0.351	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr10_+_88418147	0.344	NM_001171610	LDB3	LIM domain binding 3
chr11_+_43920385	0.344	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr2_+_87536174	0.338		NCRNA00152	non-protein coding RNA 152
chr17_-_77094375	0.335	NM_001614	ACTG1	actin, gamma 1
chr19_+_16039170	0.330	NM_001145160	TPM4	tropomyosin 4
chr16_+_29984647	0.327		ALDOA	aldolase A, fructose-bisphosphate
chr15_-_53369261	0.321	NM_183235	RAB27A	RAB27A, member RAS oncogene family
chr15_-_63147228	0.318		RASL12	RAS-like, family 12
chr20_-_62151216	0.314	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr5_-_178983241	0.312		HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr7_+_113842470	0.306		FOXP2	forkhead box P2
chr22_-_41672990	0.306	NM_007229	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr19_+_50702588	0.301		VASP	vasodilator-stimulated phosphoprotein
chr10_-_29963906	0.296	NM_021738	SVIL	supervillin
chr21_-_46528594	0.295		MCM3AP	minichromosome maintenance complex component 3 associated protein
chr11_-_8982107	0.293	NM_020645	NRIP3	nuclear receptor interacting protein 3
chr7_+_142788579	0.292		ZYX	zyxin
chr3_-_124822113	0.290	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr14_-_73296643	0.290	NM_194278	C14orf43	chromosome 14 open reading frame 43
chr3_-_9809357	0.288	NM_006354 NM_133480	TADA3	transcriptional adaptor 3
chr17_+_16259636	0.286		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr17_+_16259573	0.284	NM_016113	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr1_-_89303478	0.282	NM_002053	GBP1	guanylate binding protein 1, interferon-inducible, 67kDa
chr10_+_6226764	0.278	NM_001145443	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr15_+_31390454	0.277	NM_001036	RYR3	ryanodine receptor 3
chr6_+_12824873	0.274		PHACTR1	phosphatase and actin regulator 1
chr10_-_44794146	0.271	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr22_+_36334400	0.267	NM_001001560 NM_001001561 NM_001172687 NM_013365	GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr1_-_925332	0.265	NM_001142467 NM_021170	HES4	hairy and enhancer of split 4 (Drosophila)
chr15_+_72006015	0.264		LOXL1	lysyl oxidase-like 1
chr17_+_38256710	0.263	NM_003734	AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr17_-_34603577	0.262		CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr15_-_57452361	0.262	NM_004998	MYO1E	myosin IE
chr9_-_133574928	0.255	NM_198679	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1
chr15_-_57452357	0.254		MYO1E	myosin IE
chr8_+_24827173	0.254	NM_005382	NEFM	neurofilament, medium polypeptide
chr15_+_38430517	0.251	NM_001145643	PHGR1	proline/histidine/glycine-rich 1
chr16_+_29984611	0.251		ALDOA	aldolase A, fructose-bisphosphate
chr22_+_36334811	0.248		GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr1_-_206151055	0.248	NM_001025109 NM_001773	CD34	CD34 molecule
chr3_-_187124290	0.247		TRA2B	transformer 2 beta homolog (Drosophila)
chr6_-_16869579	0.239	NM_000332 NM_001128164	ATXN1	ataxin 1
chr20_+_2224612	0.239	NM_003245	TGM3	transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr11_-_57038891	0.238	NM_001198810	SLC43A1	solute carrier family 43, member 1
chrX_-_11194015	0.237	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr9_+_115396020	0.237	NM_144489	RGS3	regulator of G-protein signaling 3
chr2_-_27384617	0.230	NM_003353	UCN	urocortin
chr22_+_36334622	0.225		GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr6_+_44322764	0.222	NM_007355	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr5_+_131424245	0.216	NM_000588	IL3	interleukin 3 (colony-stimulating factor, multiple)
chr18_-_63333487	0.215		DSEL	dermatan sulfate epimerase-like
chr19_-_54618410	0.214	NM_178449	PTH2	parathyroid hormone 2
chr17_-_38385511	0.213	NM_025267	AARSD1	alanyl-tRNA synthetase domain containing 1
chr11_+_66070949	0.212	NM_001104	ACTN3	actinin, alpha 3
chr17_-_36938111	0.211	NM_002276	KRT19	keratin 19
chr10_-_98109048	0.211	NM_001040102 NM_001040103 NM_033207	OPALIN	oligodendrocytic myelin paranodal and inner loop protein
chr5_-_178983281	0.211	NM_005520	HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr5_+_6799100	0.211	NM_001171806	PAPD7	PAP associated domain containing 7
chr12_+_48784057	0.211	NM_005276	GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)
chr15_+_94674849	0.210	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr6_+_151602787	0.207	NM_005100	AKAP12	A kinase (PRKA) anchor protein 12
chr17_-_71017509	0.203	NM_001142643	CASKIN2	CASK interacting protein 2
chr19_+_46774370	0.197	NM_001098506 NM_033543	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21
chr16_+_29984621	0.196		ALDOA	aldolase A, fructose-bisphosphate
chr20_-_61728866	0.196		GMEB2	glucocorticoid modulatory element binding protein 2
chr3_+_150675169	0.193		TM4SF4	transmembrane 4 L six family member 4
chr5_-_131907071	0.193	NM_000879	IL5	interleukin 5 (colony-stimulating factor, eosinophil)
chr1_-_925215	0.192		HES4	hairy and enhancer of split 4 (Drosophila)
chr18_-_42810446	0.192	NM_145653	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)
chr19_-_51912136	0.189	NM_001079880 NM_001079881 NM_016457	PRKD2	protein kinase D2
chr20_+_60558369	0.188		C20orf166	chromosome 20 open reading frame 166
chr17_+_29636799	0.187	NM_002986	CCL11	chemokine (C-C motif) ligand 11
chr16_+_54247400	0.185		SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr2_-_160764819	0.181	NM_000888	ITGB6	integrin, beta 6
chr1_-_206151002	0.175		CD34	CD34 molecule
chr1_-_151699728	0.171	NM_002963	S100A7	S100 calcium binding protein A7
chr19_+_54068373	0.168		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr10_+_123912930	0.162		TACC2	transforming, acidic coiled-coil containing protein 2
chr3_+_63928459	0.161	NM_001128149	ATXN7	ataxin 7
chr9_-_97309301	0.160	NM_001083607	PTCH1	patched 1
chr19_-_63550712	0.159		A1BG	alpha-1-B glycoprotein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.09	3.20e-06	GO:0030029	actin filament-based process
6.55	1.12e-05	GO:0006936	muscle contraction
6.02	3.54e-05	GO:0003012	muscle system process
12.17	4.82e-05	GO:0030048	actin filament-based movement
1.57	6.77e-05	GO:0032501	multicellular organismal process
1.39	2.43e-04	GO:0065007	biological regulation
1.72	5.84e-04	GO:0007275	multicellular organismal development
1.66	7.86e-04	GO:0032502	developmental process
2.94	1.04e-03	GO:0010628	positive regulation of gene expression
12.70	1.16e-03	GO:0070252	actin-mediated cell contraction
2.51	1.83e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
4.87	3.25e-03	GO:0007517	muscle organ development
1.65	3.32e-03	GO:0080090	regulation of primary metabolic process
2.25	3.41e-03	GO:0009893	positive regulation of metabolic process
1.43	3.61e-03	GO:0050896	response to stimulus
1.37	3.63e-03	GO:0050789	regulation of biological process
1.38	4.16e-03	GO:0050794	regulation of cellular process
2.64	4.95e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.63	5.61e-03	GO:0031323	regulation of cellular metabolic process
2.25	6.29e-03	GO:0031325	positive regulation of cellular metabolic process
1.68	6.62e-03	GO:0048856	anatomical structure development
2.51	8.42e-03	GO:0009891	positive regulation of biosynthetic process
4.13	9.40e-03	GO:0030036	actin cytoskeleton organization
2.18	9.55e-03	GO:0010033	response to organic substance
1.71	1.13e-02	GO:0048731	system development
1.92	1.15e-02	GO:0048513	organ development
1.58	1.39e-02	GO:0023052	signaling
11.18	1.52e-02	GO:0030049	muscle filament sliding
11.18	1.52e-02	GO:0033275	actin-myosin filament sliding
7.26	1.54e-02	GO:0007015	actin filament organization
2.46	1.75e-02	GO:0031328	positive regulation of cellular biosynthetic process
2.56	1.86e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
2.19	2.18e-02	GO:0010604	positive regulation of macromolecule metabolic process
5.97	2.23e-02	GO:0032970	regulation of actin filament-based process
3.11	2.48e-02	GO:0032583	regulation of gene-specific transcription
2.52	2.50e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.73	2.93e-02	GO:0061061	muscle structure development
1.67	3.58e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.76	3.64e-02	GO:0042221	response to chemical stimulus
2.90	3.88e-02	GO:0007010	cytoskeleton organization
1.81	4.04e-02	GO:0030154	cell differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
6.27	1.61e-11	GO:0015629	actin cytoskeleton
8.41	5.47e-08	GO:0043292	contractile fiber
8.54	1.75e-07	GO:0044449	contractile fiber part
8.32	2.48e-07	GO:0030016	myofibril
7.74	3.17e-05	GO:0030017	sarcomere
9.70	6.03e-05	GO:0016459	myosin complex
2.14	1.56e-04	GO:0005856	cytoskeleton
6.97	3.09e-04	GO:0005925	focal adhesion
6.63	4.86e-04	GO:0005924	cell-substrate adherens junction
6.39	6.85e-04	GO:0030055	cell-substrate junction
13.79	6.88e-04	GO:0032432	actin filament bundle
19.15	8.00e-04	GO:0005859	muscle myosin complex
17.24	1.41e-03	GO:0016460	myosin II complex
12.17	1.48e-03	GO:0005884	actin filament
21.21	4.91e-03	GO:0031672	A band
12.31	8.14e-03	GO:0001725	stress fiber
2.13	1.10e-02	GO:0044430	cytoskeletal part
4.63	1.15e-02	GO:0005912	adherens junction
10.45	1.85e-02	GO:0042641	actomyosin
4.18	2.68e-02	GO:0070161	anchoring junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
5.02	5.31e-08	GO:0003779	actin binding
14.43	2.02e-06	GO:0008307	structural constituent of muscle
3.47	8.65e-06	GO:0008092	cytoskeletal protein binding
2.61	2.99e-05	GO:0030528	transcription regulator activity
7.66	1.59e-04	GO:0003704	specific RNA polymerase II transcription factor activity
2.44	4.72e-04	GO:0001071	nucleic acid binding transcription factor activity
2.44	4.72e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.36	7.25e-04	GO:0005515	protein binding
2.68	2.81e-03	GO:0046983	protein dimerization activity
13.79	5.72e-03	GO:0017022	myosin binding
3.65	1.46e-02	GO:0003702	RNA polymerase II transcription factor activity
2.45	1.67e-02	GO:0043565	sequence-specific DNA binding