Motif ID: TLX2.p2

Z-value: 1.571


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX2chr2_+_74595073-0.543.1e-02Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_54104383 2.244 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr3_+_153469421 1.506 MBNL1
muscleblind-like (Drosophila)
chr4_+_95592067 1.470 PDLIM5
PDZ and LIM domain 5
chr12_-_9123126 1.400 A2M
alpha-2-macroglobulin
chr7_+_106596641 1.382 NM_012257
HBP1
HMG-box transcription factor 1
chr14_+_34521945 1.253 SRP54
signal recognition particle 54kDa
chr4_+_95592030 1.161 NM_001011513
NM_001011515
NM_001011516
NM_006457
PDLIM5



PDZ and LIM domain 5



chr12_+_68150332 1.138 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr2_+_172252194 1.107 NM_001378
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr10_-_90702490 1.099 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr14_+_54104099 1.091 SAMD4A
sterile alpha motif domain containing 4A
chr14_+_34521854 1.081 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr2_-_63669265 1.074 NM_015910
WDPCP
WD repeat containing planar cell polarity effector
chr20_-_14266200 1.074 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr2_+_187163232 1.047 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr12_+_105873669 1.040 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr13_+_25726755 1.040 NM_001260
CDK8
cyclin-dependent kinase 8
chr3_-_153470022 1.035 LOC401093
hypothetical LOC401093
chr2_+_63669596 1.025 NM_005917
MDH1
malate dehydrogenase 1, NAD (soluble)
chr1_+_183281173 1.016 NM_007212
RNF2
ring finger protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
5.93 3.23e-02 GO:0006607 NLS-bearing substrate import into nucleus

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.24 3.27e-02 GO:0031974 membrane-enclosed lumen
1.16 1.45e-03 GO:0044422 organelle part
1.15 3.77e-03 GO:0044446 intracellular organelle part
1.13 1.03e-04 GO:0005737 cytoplasm
1.13 2.62e-02 GO:0044444 cytoplasmic part
1.10 1.54e-03 GO:0043229 intracellular organelle
1.10 1.80e-03 GO:0043226 organelle
1.10 2.03e-02 GO:0043227 membrane-bounded organelle
1.10 2.05e-02 GO:0043231 intracellular membrane-bounded organelle
1.08 1.73e-03 GO:0044424 intracellular part
1.07 4.89e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
7.22 2.16e-02 GO:0019864 IgG binding
1.14 3.07e-04 GO:0005515 protein binding