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Motif ID: TLX2.p2

Z-value: 1.571

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_+_54104383	2.244	NM_001161576 NM_015589	SAMD4A	sterile alpha motif domain containing 4A
chr3_+_153469421	1.506		MBNL1	muscleblind-like (Drosophila)
chr4_+_95592067	1.470		PDLIM5	PDZ and LIM domain 5
chr12_-_9123126	1.400		A2M	alpha-2-macroglobulin
chr7_+_106596641	1.382	NM_012257	HBP1	HMG-box transcription factor 1
chr14_+_34521945	1.253		SRP54	signal recognition particle 54kDa
chr4_+_95592030	1.161	NM_001011513 NM_001011515 NM_001011516 NM_006457	PDLIM5	PDZ and LIM domain 5
chr12_+_68150332	1.138	NM_001042555 NM_006654	FRS2	fibroblast growth factor receptor substrate 2
chr2_+_172252194	1.107	NM_001378	DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2
chr10_-_90702490	1.099	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr14_+_54104099	1.091		SAMD4A	sterile alpha motif domain containing 4A
chr14_+_34521854	1.081	NM_001146282 NM_003136	SRP54	signal recognition particle 54kDa
chr2_-_63669265	1.074	NM_015910	WDPCP	WD repeat containing planar cell polarity effector
chr20_-_14266200	1.074	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr2_+_187163232	1.047		ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr12_+_105873669	1.040	NM_152261	C12orf23	chromosome 12 open reading frame 23
chr13_+_25726755	1.040	NM_001260	CDK8	cyclin-dependent kinase 8
chr3_-_153470022	1.035		LOC401093	hypothetical LOC401093
chr2_+_63669596	1.025	NM_005917	MDH1	malate dehydrogenase 1, NAD (soluble)
chr1_+_183281173	1.016	NM_007212	RNF2	ring finger protein 2
chr11_+_34894688	1.007		PDHX	pyruvate dehydrogenase complex, component X
chr20_+_43283423	0.979	NM_003008	SEMG2	semenogelin II
chr4_-_75938710	0.960	NM_001729	BTC	betacellulin
chr21_+_17841297	0.941		CXADR	coxsackie virus and adenovirus receptor
chr14_-_35859545	0.935	NM_001144891 NM_016586	MBIP	MAP3K12 binding inhibitory protein 1
chr2_-_160277083	0.922		BAZ2B	bromodomain adjacent to zinc finger domain, 2B
chr2_-_74460933	0.912	NM_001135040 NM_001190837 NM_004082	DCTN1	dynactin 1
chr16_+_51722285	0.912		CHD9	chromodomain helicase DNA binding protein 9
chr1_-_92537087	0.908	NM_053274	GLMN	glomulin, FKBP associated protein
chr4_+_38545741	0.889	NM_138389	FAM114A1	family with sequence similarity 114, member A1
chr2_+_207215386	0.887	NM_001102659	LOC200726	hCG1657980
chr2_+_228386800	0.886	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr6_+_117910472	0.875	NM_173674	DCBLD1	discoidin, CUB and LCCL domain containing 1
chr17_+_64020120	0.860	NM_002734 NM_212472	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr2_+_223433919	0.848	NM_004457 NM_203372	ACSL3	acyl-CoA synthetase long-chain family member 3
chr13_+_96797290	0.847
chr20_+_56318415	0.837		RAB22A	RAB22A, member RAS oncogene family
chr14_+_30098079	0.836	NM_017769	G2E3	G2/M-phase specific E3 ubiquitin protein ligase
chr13_-_40491491	0.834	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr11_+_12652427	0.827	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_+_131190237	0.826	NM_001195597	LOC285733	hypothetical LOC285733
chr2_+_187162969	0.826	NM_001145000 NM_002210	ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr20_+_52258023	0.816		PFDN4	prefoldin subunit 4
chr8_-_125785611	0.810		MTSS1	metastasis suppressor 1
chr20_-_13713509	0.810	NM_016649	ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr1_-_151045730	0.808	NM_178351	LCE1C	late cornified envelope 1C
chr20_+_45564063	0.805		NCOA3	nuclear receptor coactivator 3
chr2_+_219141761	0.803	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr6_+_28217590	0.802	NM_006298	ZNF192	zinc finger protein 192
chr17_+_64020155	0.797		PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr6_+_160068135	0.796	NM_004906 NM_152858	WTAP	Wilms tumor 1 associated protein
chr11_+_8660913	0.789		RPL27A	ribosomal protein L27a
chr3_+_189425886	0.788	NM_001167671	LPP	LIM domain containing preferred translocation partner in lipoma
chr2_-_79168626	0.786	NM_006507	REG1B	regenerating islet-derived 1 beta
chr2_+_231629839	0.782		PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr18_+_17575542	0.782	NM_020774	MIB1	mindbomb homolog 1 (Drosophila)
chr2_+_113479919	0.779	NM_014440	IL1F6	interleukin 1 family, member 6 (epsilon)
chr1_+_24158898	0.778		PNRC2	proline-rich nuclear receptor coactivator 2
chr6_+_163904564	0.763		QKI	quaking homolog, KH domain RNA binding (mouse)
chr8_+_120289735	0.762	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_-_114176401	0.760	NM_138806 NM_138939 NM_138940 NM_170780	CD200R1	CD200 receptor 1
chr1_+_86662356	0.757	NM_006536	CLCA2	chloride channel accessory 2
chr2_-_40593074	0.756	NM_001112802	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_231629806	0.755	NM_001191037 NM_002807	PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr14_-_22610610	0.754	NM_001164816 NM_001164817	ACIN1	apoptotic chromatin condensation inducer 1
chr3_-_107070400	0.744	NM_170662	CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr10_+_82163568	0.743		C10orf58	chromosome 10 open reading frame 58
chr20_+_13713645	0.741	NM_001039375 NM_024120	C20orf7	chromosome 20 open reading frame 7
chr17_+_64020159	0.737		PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr6_-_32839244	0.732	NM_001198858	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr12_+_55808696	0.726		LRP1	low density lipoprotein receptor-related protein 1
chr20_+_45564007	0.724	NM_001174087 NM_001174088 NM_006534 NM_181659	NCOA3	nuclear receptor coactivator 3
chr13_-_40491405	0.715		ELF1	E74-like factor 1 (ets domain transcription factor)
chr20_+_42463279	0.712	NM_000457 NM_178849 NM_178850	HNF4A	hepatocyte nuclear factor 4, alpha
chr17_+_55269974	0.711
chr16_+_5061862	0.711		ALG1	asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)
chr6_+_55300225	0.707	NM_207410	GFRAL	GDNF family receptor alpha like
chr15_-_75135496	0.706		TSPAN3	tetraspanin 3
chr20_+_42463419	0.704		HNF4A	hepatocyte nuclear factor 4, alpha
chr21_+_37367432	0.702	NM_001001894	TTC3	tetratricopeptide repeat domain 3
chr1_+_195123766	0.698	NM_006684	CFHR4	complement factor H-related 4
chr3_+_180853473	0.698	NM_003940	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)
chr14_+_75688042	0.693		C14orf118	chromosome 14 open reading frame 118
chr9_-_124715392	0.691	NM_006626	ZBTB6	zinc finger and BTB domain containing 6
chr7_+_90063543	0.690		CDK14	cyclin-dependent kinase 14
chr11_-_26550243	0.688	NM_001135091 NM_001135092 NM_145650	MUC15	mucin 15, cell surface associated
chr4_-_146315341	0.688	NM_017493	OTUD4	OTU domain containing 4
chr14_-_22610572	0.682		ACIN1	apoptotic chromatin condensation inducer 1
chr1_+_24158887	0.681	NM_017761	PNRC2	proline-rich nuclear receptor coactivator 2
chr3_+_197951203	0.679		PAK2	p21 protein (Cdc42/Rac)-activated kinase 2
chr7_+_130663161	0.677		MKLN1	muskelin 1, intracellular mediator containing kelch motifs
chr10_+_88506320	0.676	NM_004329	BMPR1A	bone morphogenetic protein receptor, type IA
chr6_-_58395610	0.676		GUSBP4	glucuronidase, beta pseudogene 4
chr10_+_114700775	0.672		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_-_101384633	0.672	NM_015435	RNF19A	ring finger protein 19A
chr2_+_27848085	0.667	NM_004891 NM_145330	MRPL33	mitochondrial ribosomal protein L33
chr2_+_27848090	0.666		MRPL33	mitochondrial ribosomal protein L33
chr20_+_42463350	0.666		HNF4A	hepatocyte nuclear factor 4, alpha
chr6_+_7052798	0.664	NM_001168344	RREB1	ras responsive element binding protein 1
chr2_+_182464910	0.663		SSFA2	sperm specific antigen 2
chr14_+_75687997	0.656	NM_017926 NM_017972	C14orf118	chromosome 14 open reading frame 118
chr2_+_32244406	0.651	NM_001193513 NM_001193514 NM_001193515 NM_017964	SLC30A6	solute carrier family 30 (zinc transporter), member 6
chr1_+_114273961	0.646		HIPK1	homeodomain interacting protein kinase 1
chr19_-_56726704	0.642	NM_001177547 NM_001177548 NM_001177549 NM_001245 NM_198845 NM_198846	SIGLEC6	sialic acid binding Ig-like lectin 6
chr3_+_87359088	0.640	NM_014043	CHMP2B	chromatin modifying protein 2B
chr20_+_42463387	0.639		HNF4A	hepatocyte nuclear factor 4, alpha
chr14_+_75688025	0.638		C14orf118	chromosome 14 open reading frame 118
chr5_+_146594718	0.636	NM_001112724 NM_145001	STK32A	serine/threonine kinase 32A
chr6_+_124166767	0.636	NM_001040214 NM_153355	NKAIN2	Na+/K+ transporting ATPase interacting 2
chr20_+_43269051	0.634	NM_003007	SEMG1	semenogelin I
chr1_+_208178160	0.631	NM_001146261 NM_001146262 NM_001146264 NM_153262	SYT14	synaptotagmin XIV
chr20_+_52257800	0.631	NM_002623	PFDN4	prefoldin subunit 4
chr6_+_117109042	0.624	NM_002269	KPNA5	karyopherin alpha 5 (importin alpha 6)
chr10_+_123862430	0.623		TACC2	transforming, acidic coiled-coil containing protein 2
chr15_+_46285789	0.622	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr20_+_42947764	0.622		YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr16_+_55963899	0.621	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr7_-_80386258	0.619		SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_+_130663134	0.616	NM_013255	MKLN1	muskelin 1, intracellular mediator containing kelch motifs
chr1_-_94779727	0.615	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr3_+_187813538	0.612	NM_001622	AHSG	alpha-2-HS-glycoprotein
chr3_+_187813553	0.611		AHSG	alpha-2-HS-glycoprotein
chr14_-_24148658	0.610	NM_033423	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)
chr17_+_19853200	0.609		SPECC1	sperm antigen with calponin homology and coiled-coil domains 1
chr4_+_146250978	0.608		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr9_+_132579088	0.607	NM_007313	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase
chr19_+_2818332	0.606	NM_024967	ZNF556	zinc finger protein 556
chr22_+_29974368	0.605		LIMK2	LIM domain kinase 2
chr3_-_15814678	0.604	NM_001195098	ANKRD28	ankyrin repeat domain 28
chr3_+_12305336	0.602	NM_138711	PPARG	peroxisome proliferator-activated receptor gamma
chr14_+_38804226	0.597	NM_203354	CTAGE5	CTAGE family, member 5
chr13_+_40783340	0.595	NM_001110798 NM_024561 NM_018527	NAA16	N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr4_+_38722593	0.594	NM_001007075 NM_001171654	KLHL5	kelch-like 5 (Drosophila)
chr4_+_123311207	0.593	NM_015312	KIAA1109	KIAA1109
chr2_+_231629869	0.589		PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr16_+_55963883	0.588		CX3CL1	chemokine (C-X3-C motif) ligand 1
chr20_-_61028263	0.587		DIDO1	death inducer-obliterator 1
chr5_+_149845503	0.587		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr18_+_17575275	0.586		MIB1	mindbomb homolog 1 (Drosophila)
chr21_+_29592984	0.585		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr14_+_88099443	0.585	NM_207661	ZC3H14	zinc finger CCCH-type containing 14
chr12_-_48508411	0.585	NM_001037806	NCKAP5L	NCK-associated protein 5-like
chrX_+_154097894	0.581	NM_003372	VBP1	von Hippel-Lindau binding protein 1
chr6_+_147568795	0.578		STXBP5	syntaxin binding protein 5 (tomosyn)
chr21_+_29593088	0.574	NM_001186	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_-_61028287	0.573		DIDO1	death inducer-obliterator 1
chr2_+_160277219	0.571	NM_022826	MARCH7	membrane-associated ring finger (C3HC4) 7
chr1_+_84316217	0.570	NM_002731 NM_207578	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr3_+_187813405	0.569		AHSG	alpha-2-HS-glycoprotein
chr3_+_58452560	0.562	NM_001128214	KCTD6	potassium channel tetramerisation domain containing 6
chr15_+_38296920	0.560	NM_001128628 NM_001128629	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr11_-_22807842	0.560	NM_148893	SVIP	small VCP/p97-interacting protein
chr3_+_150330060	0.556	NM_032383	HPS3	Hermansky-Pudlak syndrome 3
chr21_+_29593607	0.556	NM_206866	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_210798232	0.555	NM_001608	ACADL	acyl-CoA dehydrogenase, long chain
chr14_+_64041170	0.554		ZBTB1	zinc finger and BTB domain containing 1
chr14_+_64041257	0.552		ZBTB1	zinc finger and BTB domain containing 1
chr2_+_231629852	0.552		PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr6_-_112186977	0.550	NM_153048	FYN	FYN oncogene related to SRC, FGR, YES
chr12_+_79995927	0.550	NM_024560	ACSS3	acyl-CoA synthetase short-chain family member 3
chr20_-_61028319	0.549	NM_001193369 NM_001193370 NM_080796	DIDO1	death inducer-obliterator 1
chr18_+_3237815	0.549		MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_160277273	0.549		MARCH7	membrane-associated ring finger (C3HC4) 7
chr12_+_67426225	0.546		SLC35E3	solute carrier family 35, member E3
chr3_-_21767819	0.544	NM_024697	ZNF385D	zinc finger protein 385D
chr13_+_59869427	0.542	NM_001146070	TDRD3	tudor domain containing 3
chr18_+_3237774	0.542		MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_84198015	0.542	NM_006982	ALX1	ALX homeobox 1
chr14_-_22825148	0.541	NM_020834	HOMEZ	homeobox and leucine zipper encoding
chr6_+_133177399	0.537	NM_001016	SNORA33 RPS12	small nucleolar RNA, H/ACA box 33 ribosomal protein S12
chr21_+_29593098	0.536		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr3_+_153469206	0.535		MBNL1	muscleblind-like (Drosophila)
chr1_+_208178198	0.535		SYT14	synaptotagmin XIV
chr7_+_30034731	0.534		PLEKHA8P1 PLEKHA8	pleckstrin homology domain containing, family A member 8 pseudogene 1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr6_+_64403936	0.532		PHF3	PHD finger protein 3
chr18_+_27332024	0.531	NM_001943	DSG2	desmoglein 2
chr16_-_66558197	0.525	NM_001145964	SLC12A4	solute carrier family 12 (potassium/chloride transporters), member 4
chr16_-_57309625	0.525		GOT2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr8_-_82186832	0.524	NM_018440	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1
chr5_-_13997588	0.522	NM_001369	DNAH5	dynein, axonemal, heavy chain 5
chr6_+_7053183	0.522		RREB1	ras responsive element binding protein 1
chr3_+_101462375	0.522	NM_018309	TBC1D23	TBC1 domain family, member 23
chr2_+_60962279	0.521		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr3_+_140545528	0.520	NM_020191	MRPS22	mitochondrial ribosomal protein S22
chr14_-_22825072	0.518		HOMEZ	homeobox and leucine zipper encoding
chr10_+_31648103	0.517	NM_001174093 NM_001174095 NM_001174096 NM_030751	ZEB1	zinc finger E-box binding homeobox 1
chr3_+_4996141	0.516		BHLHE40	basic helix-loop-helix family, member e40
chr20_+_47328585	0.513		NCRNA00275	non-protein coding RNA 275
chr8_+_26491507	0.512		DPYSL2	dihydropyrimidinase-like 2
chr5_+_118434966	0.510	NM_005509	DMXL1	Dmx-like 1
chr3_+_4996305	0.509		BHLHE40	basic helix-loop-helix family, member e40
chr13_+_26029879	0.508		WASF3	WAS protein family, member 3
chr4_+_86968069	0.508		ARHGAP24	Rho GTPase activating protein 24
chr20_+_47328575	0.504		NCRNA00275	non-protein coding RNA 275
chr20_+_42947754	0.503	NM_003404 NM_139323	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr20_-_1420168	0.502	NM_001122962 NM_001134836	SIRPB2	signal-regulatory protein beta 2
chr8_+_97575370	0.499		SDC2	syndecan 2
chr4_+_25931725	0.495		RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr14_+_23008742	0.495		NGDN	neuroguidin, EIF4E binding protein
chr2_+_152900076	0.495		FMNL2	formin-like 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.93	3.23e-02	GO:0006607	NLS-bearing substrate import into nucleus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	1.03e-04	GO:0005737	cytoplasm
1.16	1.45e-03	GO:0044422	organelle part
1.10	1.54e-03	GO:0043229	intracellular organelle
1.08	1.73e-03	GO:0044424	intracellular part
1.10	1.80e-03	GO:0043226	organelle
1.15	3.77e-03	GO:0044446	intracellular organelle part
1.07	4.89e-03	GO:0005622	intracellular
1.10	2.03e-02	GO:0043227	membrane-bounded organelle
1.10	2.05e-02	GO:0043231	intracellular membrane-bounded organelle
1.13	2.62e-02	GO:0044444	cytoplasmic part
1.24	3.27e-02	GO:0031974	membrane-enclosed lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	3.07e-04	GO:0005515	protein binding
7.22	2.16e-02	GO:0019864	IgG binding