Motif ID: VSX1,2.p2

Z-value: 0.343


Transcription factors associated with VSX1,2.p2:

Gene SymbolEntrez IDGene Name
VSX1 30813 visual system homeobox 1
VSX2 338917 visual system homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
VSX1chr20_-_25010756-0.273.1e-01Click!
VSX2chr14_+_737759270.039.2e-01Click!


Activity profile for motif VSX1,2.p2.

activity profile for motif VSX1,2.p2


Sorted Z-values histogram for motif VSX1,2.p2

Sorted Z-values for motif VSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of VSX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_190147633 0.353 TPRG1
tumor protein p63 regulated 1
chr5_+_127012611 0.315 NM_001048252
CTXN3
cortexin 3
chr8_-_10550026 0.312 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr12_+_28301399 0.255 NM_018318
CCDC91
coiled-coil domain containing 91
chr10_+_18589589 0.163 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr15_-_35180656 0.154 NM_002399
MEIS2
Meis homeobox 2
chr5_-_39430180 0.149 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr11_-_4371463 0.148 NM_003141
TRIM21
tripartite motif containing 21
chr4_+_70831387 0.144 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr4_-_90197140 0.144 NM_014883
FAM13A
family with sequence similarity 13, member A
chr16_-_20246309 0.126 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr4_+_78651929 0.121 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr12_-_25041639 0.111 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr8_-_52884456 0.108 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr9_+_130428519 0.108 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr10_-_52315390 0.102 A1CF
APOBEC1 complementation factor
chr8_+_67201684 0.097 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr9_+_131937163 0.096 GPR107
G protein-coupled receptor 107
chr16_-_71650034 0.095 NM_001164766
ZFHX3
zinc finger homeobox 3
chr11_-_117640407 0.095 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr10_+_44726635 0.094 NM_001123376
TMEM72
transmembrane protein 72
chr7_+_50318801 0.092 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr4_+_88790477 0.091 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr1_-_203592538 0.091 NM_018203
KLHDC8A
kelch domain containing 8A
chr5_+_71438796 0.091 NM_005909
MAP1B
microtubule-associated protein 1B
chr16_+_54072969 0.089 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chrX_+_7147471 0.089 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr4_+_120029426 0.086 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr11_-_20138445 0.082 NM_001029865
DBX1
developing brain homeobox 1
chr10_+_96433240 0.080 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr7_+_2524022 0.079 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_+_9450832 0.076 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr6_+_155579788 0.074 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr14_-_59264044 0.072 NM_206857
RTN1
reticulon 1
chr4_-_57242492 0.072 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr1_+_198263352 0.070 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr3_+_2528272 0.068 CNTN4
contactin 4
chr1_-_108032645 0.066 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr1_-_156816312 0.062 NM_001004477
OR10X1
olfactory receptor, family 10, subfamily X, member 1
chr8_-_62764839 0.061 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr19_+_56766342 0.060 NM_007147
ZNF175
zinc finger protein 175
chr11_+_59979857 0.059 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr3_-_25658829 0.058 TOP2B
topoisomerase (DNA) II beta 180kDa
chr11_+_17697685 0.058 NM_002478
MYOD1
myogenic differentiation 1
chr8_+_92330691 0.057 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr11_-_118405288 0.057 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr8_+_9450800 0.057 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr12_+_15590552 0.055 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr1_-_103269356 0.055 COL11A1
collagen, type XI, alpha 1
chr2_-_99238001 0.053 NM_175735
LYG2
lysozyme G-like 2
chr1_+_28134090 0.053 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr1_+_144183811 0.051 ANKRD34A
ankyrin repeat domain 34A
chr10_-_50066386 0.050 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr6_+_49575629 0.048 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr1_+_28458546 0.048 NM_031459
SESN2
sestrin 2
chr2_+_28892366 0.047 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr1_-_171441234 0.044 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr11_-_89181390 0.042 NM_020358
TRIM49
tripartite motif containing 49
chr2_-_80384454 0.042 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr5_-_9683462 0.042 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr18_+_3437607 0.042 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr10_+_32896656 0.041 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr6_+_127940011 0.040 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr13_-_40491405 0.040 ELF1
E74-like factor 1 (ets domain transcription factor)
chr6_+_28425666 0.039 NM_024493
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr1_+_145892190 0.039 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr1_+_205293217 0.039 NM_001018053
NM_006212
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr16_+_47965308 0.038 NM_144602
C16orf78
chromosome 16 open reading frame 78
chr14_-_77152862 0.037 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr7_-_87180499 0.037 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr11_-_123695302 0.035 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr21_-_30642794 0.035 NM_181624
KRTAP23-1
keratin associated protein 23-1
chr1_-_149004852 0.034 CTSS
cathepsin S
chr7_+_1239078 0.034 NM_001080461
UNCX
UNC homeobox
chr3_-_102522093 0.033 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr9_+_115396020 0.033 NM_144489
RGS3
regulator of G-protein signaling 3
chr12_-_52016270 0.033 NM_001173467
SP7
Sp7 transcription factor
chr8_+_9990471 0.032 NM_001135671
MSRA
methionine sulfoxide reductase A
chr12_-_55979413 0.032


chrX_-_107221405 0.032 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr12_+_91620749 0.032 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr18_-_28606839 0.031 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr1_-_158098962 0.031 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr7_+_113853790 0.031 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr2_+_189547358 0.031 COL3A1
collagen, type III, alpha 1
chr6_+_160462852 0.031 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr6_+_132901119 0.030 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chrX_-_24600661 0.030 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr4_-_66218777 0.029 EPHA5
EPH receptor A5
chr4_-_74704964 0.029 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr4_-_100284395 0.029 NM_000670
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr3_-_173911467 0.029 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr3_+_161040343 0.029 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr14_+_101345878 0.028 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr2_-_65013070 0.028 LOC400958
hypothetical LOC400958
chr4_-_169476391 0.027 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr17_+_7732759 0.027 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr4_-_138673014 0.024 PCDH18
protocadherin 18
chr7_-_88262966 0.024 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr7_-_44547382 0.024 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr10_-_52315436 0.023 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr18_+_44319365 0.023 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr1_-_230717850 0.023 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr1_-_150653351 0.022 NM_016190
CRNN
cornulin
chr12_-_4358968 0.022 NM_020638
FGF23
fibroblast growth factor 23
chr4_-_164614335 0.022 NM_032136
TKTL2
transketolase-like 2
chrX_-_23835868 0.021 NM_024122
APOO
apolipoprotein O
chr8_-_117837240 0.021 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr11_-_30910074 0.021 NM_020869
DCDC5
doublecortin domain containing 5
chr13_+_47948586 0.020 RB1
retinoblastoma 1
chr4_+_70928718 0.019 NM_000200
HTN3
histatin 3
chr3_+_153468518 0.019 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr8_+_54926920 0.018 NM_170587
RGS20
regulator of G-protein signaling 20
chr11_-_117640078 0.018


chr7_+_116447527 0.018 ST7
suppression of tumorigenicity 7
chrX_+_107174855 0.018 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr8_-_134156437 0.018 SLA
Src-like-adaptor
chr1_-_153916221 0.017 NM_001198899
YY1AP1
YY1 associated protein 1
chr17_+_18027816 0.017 ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr4_+_5577783 0.017 NM_005750
C4orf6
chromosome 4 open reading frame 6
chr11_+_89403921 0.017 NM_001195234
TRIM49
TRIM49L2
tripartite motif containing 49
tripartite motif containing 49-like 2
chr9_+_66197108 0.017


chr11_-_102250876 0.017 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr17_-_26648375 0.017 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr13_-_33148899 0.017 STARD13
StAR-related lipid transfer (START) domain containing 13
chr14_+_75058591 0.017 BATF
basic leucine zipper transcription factor, ATF-like
chr6_+_151688327 0.016 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_117640166 0.016 MPZL2
myelin protein zero-like 2
chr2_+_202379442 0.016 NM_139158
CDK15
cyclin-dependent kinase 15
chr14_+_31868229 0.016 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr6_-_52818851 0.016 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr21_-_36836767 0.016 NM_001146078
CLDN14
claudin 14
chr9_-_19778590 0.015 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr10_-_98311813 0.015 TM9SF3
transmembrane 9 superfamily member 3
chr2_-_218739891 0.015 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr20_-_19981005 0.014 CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr12_+_18305740 0.014 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr1_-_184684478 0.014 NM_022576
PDC
phosducin
chr3_-_166278969 0.013 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr12_-_119733062 0.013 SPPL3
signal peptide peptidase 3
chr11_+_65740789 0.013 PACS1
phosphofurin acidic cluster sorting protein 1
chr6_+_105511615 0.013 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr16_+_4322225 0.012 NM_032575
GLIS2
GLIS family zinc finger 2
chr2_+_128119908 0.012 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr1_+_158426908 0.012 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_-_111119846 0.012 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr12_+_15590811 0.012 PTPRO
protein tyrosine phosphatase, receptor type, O
chr11_-_5279750 0.012 NM_033179
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr7_+_104539548 0.011 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr1_-_27825633 0.011 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr3_+_123256902 0.011 NM_175862
CD86
CD86 molecule
chr1_+_100776280 0.011 NM_022049
GPR88
G protein-coupled receptor 88
chr8_-_117837224 0.011 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr11_-_33870411 0.011 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr7_+_141457977 0.010 LOC93432
maltase-glucoamylase-like pseudogene
chr16_-_87280380 0.010 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr12_-_54392328 0.009 NM_001144997
ITGA7
integrin, alpha 7
chr19_-_40711034 0.009 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr8_+_39911630 0.009 NM_194294
IDO2
indoleamine 2,3-dioxygenase 2
chr8_-_117837202 0.008 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr7_+_37689903 0.008


chr1_+_28637247 0.008 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr15_+_97990705 0.007 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr3_+_2117246 0.007 NM_175607
CNTN4
contactin 4
chr2_-_101291483 0.007 NM_173647
RNF149
ring finger protein 149
chr7_+_128136347 0.007 FAM71F1
family with sequence similarity 71, member F1
chr4_-_123596921 0.007 NM_000586
IL2
interleukin 2
chr4_+_74520796 0.006 NM_001134
AFP
alpha-fetoprotein
chr5_-_96504216 0.006 LIX1
Lix1 homolog (chicken)
chr1_+_175406685 0.006 FAM5B
family with sequence similarity 5, member B
chr5_+_36642424 0.006 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_122357104 0.006 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr6_-_52776558 0.006 NM_145740
GSTA1
glutathione S-transferase alpha 1
chr5_-_96504194 0.006 LIX1
Lix1 homolog (chicken)
chr10_+_5126613 0.005 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr8_-_17787342 0.005 FGL1
fibrinogen-like 1
chr9_-_205892 0.005 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr1_+_220977180 0.005 NM_207468
FAM177B
family with sequence similarity 177, member B
chr7_-_83662152 0.005 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_22835684 0.005 NM_015991
C1QA
complement component 1, q subcomponent, A chain
chr11_+_59920062 0.005 NM_001079692
NM_032597
MS4A14

membrane-spanning 4-domains, subfamily A, member 14

chr1_+_111571803 0.005 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr19_-_41514390 0.005


chr11_+_26972244 0.004 FIBIN
fin bud initiation factor homolog (zebrafish)
chr11_+_59804634 0.004 NM_148975
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4
chr10_+_95362334 0.004 NM_006204
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr2_-_190635566 0.004 NM_005259
MSTN
myostatin
chr13_+_110637173 0.004 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr15_-_64644758 0.004 NM_207338
LCTL
lactase-like
chr16_+_31178812 0.004 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr10_+_5126589 0.003 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_-_36403910 0.003 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr4_-_68793928 0.003 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr20_+_58004811 0.003 NM_021810
CDH26
cadherin 26
chr8_-_87824996 0.003 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr1_-_198643885 0.003 ZNF281
zinc finger protein 281
chr2_+_108571177 0.003 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_-_56814310 0.003 NM_001017992
ACTBL2
actin, beta-like 2
chr17_-_36165050 0.003 NM_181534
KRT25
keratin 25
chr11_+_26972203 0.002 NM_203371
FIBIN
fin bud initiation factor homolog (zebrafish)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.