Motif ID: TFAP4.p2

Z-value: 2.473


Transcription factors associated with TFAP4.p2:

Gene SymbolEntrez IDGene Name
TFAP4 7023 transcription factor AP-4 (activating enhancer binding protein 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFAP4chr16_-_42626960.674.7e-03Click!


Activity profile for motif TFAP4.p2.

activity profile for motif TFAP4.p2


Sorted Z-values histogram for motif TFAP4.p2

Sorted Z-values for motif TFAP4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_13090101 4.627 NM_052876
 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr16_-_87405817 3.249 NM_000485
NM_001030018
 APRT

adenine phosphoribosyltransferase

chr22_+_20068039 3.056 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr19_+_1236766 2.939 NM_001405
 EFNA2
ephrin-A2
chr19_+_530466 2.847 BSG
basigin (Ok blood group)
chr20_-_61669550 2.739 NM_033405
 PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr9_+_139292094 2.666 NM_017723
 C9orf167
chromosome 9 open reading frame 167
chr6_+_32114060 2.566 NM_000500
NM_001128590
 CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr3_-_12983959 2.428 NM_014869
 IQSEC1
IQ motif and Sec7 domain 1
chr19_+_10392128 2.363 NM_001111307
 PDE4A
phosphodiesterase 4A, cAMP-specific
chr22_+_19649417 2.206 NM_001018060
NM_144704
 AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr7_+_1239078 2.197 NM_001080461
 UNCX
UNC homeobox
chr19_+_590878 2.187 NM_020637
 FGF22
fibroblast growth factor 22
chr12_-_50871953 2.158 NM_001081492
NM_182507
 KRT80

keratin 80

chr8_+_144711619 2.154 NM_024736
 GSDMD
gasdermin D
chr2_+_128119908 2.089 NM_001161415
NM_001161416
NM_001161417
NM_005291
 GPR17



G protein-coupled receptor 17



chr9_+_133154896 1.991 NM_032728
 PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr2_+_233029076 1.944 NM_001631
 ALPI
alkaline phosphatase, intestinal
chr19_-_13808101 1.924 LOC284454
hypothetical LOC284454
chr1_+_200429740 1.902 NM_001017403
 LGR6
leucine-rich repeat containing G protein-coupled receptor 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.52 6.44e-03 GO:0006937 regulation of muscle contraction
1.38 1.25e-02 GO:0006811 ion transport
1.37 3.18e-02 GO:0040011 locomotion
1.36 1.33e-02 GO:0032879 regulation of localization
1.28 2.61e-02 GO:0007399 nervous system development
1.26 3.86e-04 GO:0042221 response to chemical stimulus
1.25 2.22e-02 GO:0007166 cell surface receptor linked signaling pathway
1.24 9.40e-08 GO:0023052 signaling
1.22 5.65e-05 GO:0007165 signal transduction
1.21 3.30e-03 GO:0048731 system development
1.19 1.71e-03 GO:0007275 multicellular organismal development
1.17 2.93e-03 GO:0051716 cellular response to stimulus
1.15 4.79e-02 GO:0032502 developmental process
1.12 1.50e-05 GO:0065007 biological regulation
1.12 4.49e-04 GO:0050789 regulation of biological process
1.12 1.59e-03 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.95 9.86e-03 GO:0031225 anchored to membrane
1.85 4.44e-03 GO:0016324 apical plasma membrane
1.56 2.19e-02 GO:0005578 proteinaceous extracellular matrix
1.53 1.23e-02 GO:0009986 cell surface
1.27 1.32e-05 GO:0044459 plasma membrane part
1.21 1.81e-02 GO:0005576 extracellular region
1.14 9.38e-03 GO:0005886 plasma membrane
1.13 1.85e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.46 3.99e-02 GO:0030695 GTPase regulator activity
1.36 2.93e-02 GO:0015075 ion transmembrane transporter activity