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Motif ID: TFAP4.p2

Z-value: 2.473

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_13090101	4.627	NM_052876	NACC1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr16_-_87405817	3.249	NM_000485 NM_001030018	APRT	adenine phosphoribosyltransferase
chr22_+_20068039	3.056	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr19_+_1236766	2.939	NM_001405	EFNA2	ephrin-A2
chr19_+_530466	2.847		BSG	basigin (Ok blood group)
chr20_-_61669550	2.739	NM_033405	PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285
chr9_+_139292094	2.666	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr6_+_32114060	2.566	NM_000500 NM_001128590	CYP21A2	cytochrome P450, family 21, subfamily A, polypeptide 2
chr3_-_12983959	2.428	NM_014869	IQSEC1	IQ motif and Sec7 domain 1
chr19_+_10392128	2.363	NM_001111307	PDE4A	phosphodiesterase 4A, cAMP-specific
chr22_+_19649417	2.206	NM_001018060 NM_144704	AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr7_+_1239078	2.197	NM_001080461	UNCX	UNC homeobox
chr19_+_590878	2.187	NM_020637	FGF22	fibroblast growth factor 22
chr12_-_50871953	2.158	NM_001081492 NM_182507	KRT80	keratin 80
chr8_+_144711619	2.154	NM_024736	GSDMD	gasdermin D
chr2_+_128119908	2.089	NM_001161415 NM_001161416 NM_001161417 NM_005291	GPR17	G protein-coupled receptor 17
chr9_+_133154896	1.991	NM_032728	PPAPDC3	phosphatidic acid phosphatase type 2 domain containing 3
chr2_+_233029076	1.944	NM_001631	ALPI	alkaline phosphatase, intestinal
chr19_-_13808101	1.924		LOC284454	hypothetical LOC284454
chr1_+_200429740	1.902	NM_001017403	LGR6	leucine-rich repeat containing G protein-coupled receptor 6
chr19_+_2200112	1.897	NM_000479	AMH	anti-Mullerian hormone
chr11_+_43920385	1.880	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr1_-_6402467	1.843	NM_019089	HES2	hairy and enhancer of split 2 (Drosophila)
chr7_+_2525922	1.782	NM_001040167 NM_001040168	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_-_132804243	1.770	NM_001145106	FIBCD1	fibrinogen C domain containing 1
chr3_-_13032130	1.741
chr22_+_19248733	1.718		MED15	mediator complex subunit 15
chr9_-_139183675	1.717
chr4_+_8322358	1.688	NM_053044	HTRA3	HtrA serine peptidase 3
chr10_+_134060681	1.688	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr10_+_80498782	1.685	NM_020338	ZMIZ1	zinc finger, MIZ-type containing 1
chr16_+_2461500	1.645	NM_006181	NTN3	netrin 3
chr19_+_3473953	1.637	NM_001136197 NM_001136198	FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)
chr1_-_226202210	1.636	NM_003395	WNT9A	wingless-type MMTV integration site family, member 9A
chr6_+_37245860	1.617	NM_002648	PIM1	pim-1 oncogene
chr19_+_55164668	1.602		SIGLEC16	sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr8_-_145085616	1.601	NM_201384	PLEC	plectin
chr1_+_1940605	1.584	NM_000815	GABRD	gamma-aminobutyric acid (GABA) A receptor, delta
chr5_+_176726918	1.579		RGS14	regulator of G-protein signaling 14
chr19_+_3045528	1.567		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr11_-_75595098	1.534	NM_004626	WNT11	wingless-type MMTV integration site family, member 11
chr17_+_77453363	1.529	NM_148896	NPB	neuropeptide B
chr1_-_21868380	1.523	NM_001145657 NM_002885	RAP1GAP	RAP1 GTPase activating protein
chr7_+_100515439	1.506	NM_030961	TRIM56	tripartite motif containing 56
chr1_-_37991160	1.497		EPHA10	EPH receptor A10
chr8_+_145705253	1.491	NM_138431	MFSD3	major facilitator superfamily domain containing 3
chr10_+_135343649	1.482	NM_012147	DUX2	double homeobox 2
chr10_+_72826656	1.477	NM_001171930 NM_001171931 NM_001171932 NM_022124 NM_052836	CDH23	cadherin-related 23
chr16_+_711139	1.475	NM_023933	FAM173A	family with sequence similarity 173, member A
chr1_+_3378030	1.454		ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16
chr11_-_75599433	1.422		WNT11	wingless-type MMTV integration site family, member 11
chrX_-_106846253	1.411	NM_001015881	TSC22D3	TSC22 domain family, member 3
chr19_+_44266784	1.409	NM_001004318	PAPL	iron/zinc purple acid phosphatase-like protein
chr11_+_2422747	1.402	NM_000218	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1
chr12_+_108636569	1.401	NM_032829	C12orf34	chromosome 12 open reading frame 34
chr7_-_127833231	1.400	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr4_+_8633116	1.394	NM_080819	GPR78	G protein-coupled receptor 78
chr11_+_74629597	1.392	NM_001195528	LOC441617	hypothetical LOC441617
chr22_+_20101661	1.391	NM_015094	HIC2	hypermethylated in cancer 2
chr8_-_140784416	1.391	NM_016601	KCNK9	potassium channel, subfamily K, member 9
chr2_+_94900904	1.383	NM_144705	TEKT4	tektin 4
chr1_+_1256585	1.382	NM_152228	TAS1R3	taste receptor, type 1, member 3
chr19_-_54857003	1.379		IRF3	interferon regulatory factor 3
chr21_+_42946719	1.379	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr2_+_3620296	1.378	NM_024027 NM_199235	COLEC11	collectin sub-family member 11
chr11_-_66877519	1.378	NM_021173	POLD4	polymerase (DNA-directed), delta 4
chr16_+_84204424	1.360	NM_014615	KIAA0182	KIAA0182
chr4_+_3413489	1.335	NM_001528	HGFAC	HGF activator
chr20_-_61933012	1.334		ZBTB46	zinc finger and BTB domain containing 46
chr15_-_75693309	1.332		LINGO1	leucine rich repeat and Ig domain containing 1
chr16_-_1215254	1.326	NM_012467	TPSG1	tryptase gamma 1
chr21_+_44844924	1.323	NM_198689	KRTAP10-7	keratin associated protein 10-7
chr7_+_154943466	1.321	NM_001427	EN2	engrailed homeobox 2
chr22_-_20235372	1.318	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr19_+_46390916	1.308	NM_030622	CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1
chr20_+_61838479	1.307		LIME1	Lck interacting transmembrane adaptor 1
chr3_+_135996990	1.302		EPHB1	EPH receptor B1
chr19_-_59438411	1.300	NM_024318	LILRB3 LILRA6	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr1_-_1171964	1.297	NM_001014980	FAM132A	family with sequence similarity 132, member A
chr3_+_151608673	1.289		TSC22D2	TSC22 domain family, member 2
chr12_+_50981915	1.288	NM_002284	KRT86	keratin 86
chr11_-_66945190	1.281		PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_-_6474346	1.276	NM_020631	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr8_-_145090892	1.275	NM_201381	PLEC	plectin
chr22_+_17539198	1.272
chr17_+_7269658	1.272	NM_175734	C17orf74	chromosome 17 open reading frame 74
chr10_+_135333667	1.267	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr6_-_168219380	1.257	NM_001122841	FRMD1	FERM domain containing 1
chr19_-_3928516	1.252		EEF2	eukaryotic translation elongation factor 2
chr19_+_46390980	1.246		CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1
chr19_+_54883732	1.243	NM_001101340	C19orf76	chromosome 19 open reading frame 76
chr3_-_50515857	1.237	NM_001005505 NM_001174051 NM_006030	CACNA2D2	calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr8_-_142307854	1.235	NM_001080431	SLC45A4	solute carrier family 45, member 4
chr22_-_19122047	1.232		SCARF2	scavenger receptor class F, member 2
chr1_-_6585268	1.228		KLHL21	kelch-like 21 (Drosophila)
chr4_+_3737872	1.227		ADRA2C	adrenergic, alpha-2C-, receptor
chr2_-_233060774	1.226	NM_004826	ECEL1	endothelin converting enzyme-like 1
chr12_+_106236281	1.225	NM_001018072	BTBD11	BTB (POZ) domain containing 11
chr1_-_155095289	1.223	NM_014215	INSRR	insulin receptor-related receptor
chr14_+_104117100	1.217	NM_001008404	C14orf180	chromosome 14 open reading frame 180
chr8_-_145099963	1.216	NM_201379	PLEC	plectin
chr9_+_130620540	1.208	NM_004435	ENDOG	endonuclease G
chr5_-_525916	1.201		LOC25845	hypothetical LOC25845
chr1_-_925332	1.197	NM_001142467 NM_021170	HES4	hairy and enhancer of split 4 (Drosophila)
chr1_+_1360765	1.189	NM_022834 NM_199121	VWA1	von Willebrand factor A domain containing 1
chr20_+_61838389	1.188	NM_017806	LIME1	Lck interacting transmembrane adaptor 1
chr16_-_11270619	1.185	NM_005425	TNP2	transition protein 2 (during histone to protamine replacement)
chr2_+_241156776	1.183	NM_018226	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1
chr14_+_99859427	1.170	NM_207117	SLC25A47	solute carrier family 25, member 47
chr21_+_44569537	1.169		PFKL	phosphofructokinase, liver
chr1_-_1525309	1.166		LOC643988	hypothetical LOC643988
chr22_+_19248810	1.160		MED15	mediator complex subunit 15
chr19_-_1062972	1.154		SBNO2	strawberry notch homolog 2 (Drosophila)
chr7_-_158073121	1.153	NM_002847 NM_130842 NM_130843	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr19_+_3045266	1.141	NM_002067	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr22_+_19649460	1.139		AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr7_+_73341640	1.134	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr9_-_139047112	1.129	NM_004479	FUT7	fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr1_+_1099145	1.128	NM_001130045	TTLL10	tubulin tyrosine ligase-like family, member 10
chr4_+_191232653	1.127	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr17_+_75507750	1.124
chr10_+_88404285	1.114	NM_001030015 NM_033282	OPN4	opsin 4
chr4_+_191239247	1.114	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr8_+_145461356	1.109	NM_001008271 NM_001080514	SCXA SCXB	scleraxis homolog A (mouse) scleraxis homolog B (mouse)
chr9_-_128924782	1.094		ANGPTL2	angiopoietin-like 2
chr16_+_73810383	1.093	NM_001906	CTRB1 CTRB2	chymotrypsinogen B1 chymotrypsinogen B2
chr22_-_42619139	1.092	NM_001177675 NM_138814	PNPLA5	patatin-like phospholipase domain containing 5
chr22_-_19122107	1.091	NM_153334 NM_182895	SCARF2	scavenger receptor class F, member 2
chr19_+_482688	1.077	NM_004359	CDC34	cell division cycle 34 homolog (S. cerevisiae)
chr1_+_6226838	1.074	NM_001024598	HES3	hairy and enhancer of split 3 (Drosophila)
chr10_+_80740584	1.069		ZMIZ1	zinc finger, MIZ-type containing 1
chr22_+_49333327	1.060	NM_138433	KLHDC7B	kelch domain containing 7B
chr17_-_3447084	1.060	NM_018727	TRPV1	transient receptor potential cation channel, subfamily V, member 1
chr3_+_135996734	1.059	NM_004441	EPHB1	EPH receptor B1
chr1_+_1104939	1.057	NM_153254	TTLL10	tubulin tyrosine ligase-like family, member 10
chr19_+_55571493	1.055	NM_007121	NR1H2	nuclear receptor subfamily 1, group H, member 2
chr19_-_50355247	1.051	NM_198478	NKPD1	NTPase, KAP family P-loop domain containing 1
chr9_-_128924819	1.040	NM_012098	ANGPTL2	angiopoietin-like 2
chr21_+_43462209	1.033	NM_000394	CRYAA	crystallin, alpha A
chr3_-_10027770	1.031	NM_001008737	LOC401052	hypothetical LOC401052
chr22_-_30928497	1.031	NM_001159546	RFPL2	ret finger protein-like 2
chrX_-_55037235	1.028	NM_002625	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_+_152806874	1.014	NM_000748	CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
chr10_+_135330357	1.012	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr19_-_2378874	1.008	NM_012458	TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr1_+_154878498	1.007		BCAN	brevican
chr11_-_785005	1.006		SLC25A22	solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr20_-_61639104	1.004	NM_005975	PTK6	PTK6 protein tyrosine kinase 6
chr8_-_41624030	1.004	NM_152568	NKX6-3	NK6 homeobox 3
chr17_-_36346240	1.003		KRT23	keratin 23 (histone deacetylase inducible)
chr17_-_29930431	1.002	NM_207454	C17orf102	chromosome 17 open reading frame 102
chr19_-_3922032	1.000		DAPK3	death-associated protein kinase 3
chr22_-_15982142	1.000	NM_031890 NM_001163079	CECR6	cat eye syndrome chromosome region, candidate 6
chr7_+_45163891	1.000	NM_005856	RAMP3	receptor (G protein-coupled) activity modifying protein 3
chr1_-_39871226	0.993		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr17_+_14145051	0.989	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr16_-_790699	0.988	NM_016541	GNG13	guanine nucleotide binding protein (G protein), gamma 13
chr12_+_130878870	0.987	NM_016155	MMP17	matrix metallopeptidase 17 (membrane-inserted)
chr1_-_1840564	0.979	NM_178545	TMEM52	transmembrane protein 52
chr16_+_2226468	0.979	NM_001374	DNASE1L2	deoxyribonuclease I-like 2
chr19_+_482737	0.979		CDC34	cell division cycle 34 homolog (S. cerevisiae)
chr11_+_65100074	0.977	NM_001099409	EHBP1L1	EH domain binding protein 1-like 1
chr19_-_8118367	0.976	NM_032447	FBN3	fibrillin 3
chr4_+_191235959	0.973	NM_001177376	DUX4L4	double homeobox 4 like 4
chr7_+_128293699	0.971	NM_001195150	LOC100130705	hypothetical protein LOC100130705
chr9_+_139255559	0.966		TUBB2C	tubulin, beta 2C
chr15_-_66285427	0.964	NM_001031733 NM_033429	CALML4	calmodulin-like 4
chr1_+_152806924	0.959		CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
chr11_+_67567022	0.959	NM_006053	TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr1_-_20122638	0.958	NM_014589	PLA2G2E	phospholipase A2, group IIE
chr19_+_18543613	0.958	NM_001033930 NM_003333	UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1
chr18_+_75724655	0.955	NM_012283	KCNG2	potassium voltage-gated channel, subfamily G, member 2
chr9_-_128924706	0.955		ANGPTL2	angiopoietin-like 2
chr1_-_6243621	0.954	NM_207370	GPR153	G protein-coupled receptor 153
chr3_-_195553297	0.942	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr3_-_48516486	0.940	NM_016479	SHISA5	shisa homolog 5 (Xenopus laevis)
chr19_-_3922089	0.935		DAPK3	death-associated protein kinase 3
chr9_-_138958889	0.927		FBXW5	F-box and WD repeat domain containing 5
chr20_+_1254033	0.925		LOC100507495	hypothetical LOC100507495
chr1_+_148788410	0.924	NM_019032 NM_025008	ADAMTSL4	ADAMTS-like 4
chr11_-_118693021	0.921	NM_006500	MCAM	melanoma cell adhesion molecule
chr6_+_108593907	0.907	NM_003269	NR2E1	nuclear receptor subfamily 2, group E, member 1
chr19_-_3931499	0.907		EEF2	eukaryotic translation elongation factor 2
chr7_-_127458231	0.907	NM_022143	LRRC4	leucine rich repeat containing 4
chr2_+_232165818	0.906	NM_152614	C2orf57	chromosome 2 open reading frame 57
chr1_+_44643513	0.904	NM_018150	RNF220	ring finger protein 220
chrX_+_67784235	0.903	NM_001142503 NM_014725	STARD8	StAR-related lipid transfer (START) domain containing 8
chr6_+_31538934	0.902	NM_006674	HCP5	HLA complex P5
chr20_-_61108831	0.900	NM_080606	BHLHE23	basic helix-loop-helix family, member e23
chr19_+_6415259	0.900	NM_139161 NM_174881	CRB3	crumbs homolog 3 (Drosophila)
chr8_-_145097031	0.897	NM_201380	PLEC	plectin
chr16_-_87460514	0.894	NM_001080487	PABPN1L	poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr4_+_191226073	0.893	NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467	DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3	double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3
chr16_+_2138608	0.893	NM_014353	RAB26	RAB26, member RAS oncogene family
chr11_-_46364681	0.886	NM_000741	CHRM4	cholinergic receptor, muscarinic 4
chr20_-_21442663	0.884	NM_002509	NKX2-2	NK2 homeobox 2
chr9_+_139255519	0.883	NM_006088	TUBB2C	tubulin, beta 2C
chr10_+_71908535	0.882	NM_014431	KIAA1274	KIAA1274
chr9_-_135213149	0.881		SURF1	surfeit 1
chr17_-_77462506	0.880	NM_001184917 NM_002861	PCYT2	phosphate cytidylyltransferase 2, ethanolamine

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.24	9.40e-08	GO:0023052	signaling
1.12	1.50e-05	GO:0065007	biological regulation
1.22	5.65e-05	GO:0007165	signal transduction
1.26	3.86e-04	GO:0042221	response to chemical stimulus
1.12	4.49e-04	GO:0050789	regulation of biological process
1.12	1.59e-03	GO:0050794	regulation of cellular process
1.19	1.71e-03	GO:0007275	multicellular organismal development
1.17	2.93e-03	GO:0051716	cellular response to stimulus
1.21	3.30e-03	GO:0048731	system development
2.52	6.44e-03	GO:0006937	regulation of muscle contraction
1.38	1.25e-02	GO:0006811	ion transport
1.36	1.33e-02	GO:0032879	regulation of localization
1.25	2.22e-02	GO:0007166	cell surface receptor linked signaling pathway
1.28	2.61e-02	GO:0007399	nervous system development
1.37	3.18e-02	GO:0040011	locomotion
1.15	4.79e-02	GO:0032502	developmental process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.27	1.32e-05	GO:0044459	plasma membrane part
1.85	4.44e-03	GO:0016324	apical plasma membrane
1.14	9.38e-03	GO:0005886	plasma membrane
1.95	9.86e-03	GO:0031225	anchored to membrane
1.53	1.23e-02	GO:0009986	cell surface
1.21	1.81e-02	GO:0005576	extracellular region
1.13	1.85e-02	GO:0071944	cell periphery
1.56	2.19e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.36	2.93e-02	GO:0015075	ion transmembrane transporter activity
1.46	3.99e-02	GO:0030695	GTPase regulator activity