Motif ID: MYBL2.p2

Z-value: 0.922


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBL2chr20_+_417291220.077.9e-01Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_32340291 1.122 NM_004011
NM_004012
DMD

dystrophin

chr2_+_170074457 1.036 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr5_+_43645018 1.029 NNT
nicotinamide nucleotide transhydrogenase
chr15_+_41597097 0.953 NM_002373
MAP1A
microtubule-associated protein 1A
chr3_+_187840842 0.821 NM_014375
FETUB
fetuin B
chr1_+_146843980 0.803 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr4_+_120276386 0.725 NM_016599
MYOZ2
myozenin 2
chr1_+_143326315 0.680 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr22_+_38652555 0.672 GRAP2
GRB2-related adaptor protein 2
chr1_-_120189301 0.660 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr11_-_10487212 0.658 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr16_-_86527608 0.627 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr9_-_94338072 0.617 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr11_-_85103438 0.599 NM_032379
SYTL2
synaptotagmin-like 2
chr3_-_198784590 0.597 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr1_-_197173159 0.584 LOC100131234
familial acute myelogenous leukemia related factor
chr12_-_61283474 0.583 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr5_+_179934143 0.563 CNOT6
CCR4-NOT transcription complex, subunit 6
chr5_-_159778621 0.555 NM_006425
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chrX_-_19898302 0.549 NM_198279
CXorf23
chromosome X open reading frame 23
chr4_-_39655554 0.545 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr12_+_105602606 0.543 NM_032491
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr11_+_54867202 0.542 NM_001005274
OR4A16
olfactory receptor, family 4, subfamily A, member 16
chr17_-_45582872 0.540 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr13_-_45323757 0.537 NM_198849
SIAH3
seven in absentia homolog 3 (Drosophila)
chr3_-_124821868 0.519 MYLK
myosin light chain kinase
chr4_+_3341521 0.517 NM_198227
RGS12
regulator of G-protein signaling 12
chr1_-_24307514 0.508 MYOM3
myomesin family, member 3
chr3_+_158637273 0.491 NM_002852
PTX3
pentraxin 3, long
chr14_+_61532293 0.487 NM_031914
SYT16
synaptotagmin XVI
chr7_+_133884388 0.483 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr4_-_39655944 0.468 NM_001100399
NM_001100400
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr5_-_54317102 0.467 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chrX_-_10548458 0.452 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr1_+_20269239 0.449 NM_000929
PLA2G5
phospholipase A2, group V
chr11_-_106941633 0.444 NM_138775
ALKBH8
alkB, alkylation repair homolog 8 (E. coli)
chr7_+_104539548 0.430 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr17_-_55958274 0.426 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_-_70329067 0.418 NM_022037
NM_022173
TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr18_-_50134940 0.413 NM_139171
STARD6
StAR-related lipid transfer (START) domain containing 6
chr14_+_66901237 0.409 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr21_+_29439768 0.390 C21orf7
chromosome 21 open reading frame 7
chr12_+_7039453 0.386


chr3_-_47909001 0.385 MAP4
microtubule-associated protein 4
chr21_-_29179482 0.378 NM_013240
NM_182749
N6AMT1

N-6 adenine-specific DNA methyltransferase 1 (putative)

chr4_-_41579325 0.369


chr4_+_69996780 0.367 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr12_-_15757114 0.365 EPS8
epidermal growth factor receptor pathway substrate 8
chr10_-_98021144 0.358 NM_001114094
NM_013314
BLNK

B-cell linker

chr2_-_36929520 0.357 STRN
striatin, calmodulin binding protein
chr10_+_17310475 0.357 VIM
vimentin
chr10_+_104525877 0.354 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr4_-_70547962 0.350 NM_006798
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr10_+_17310263 0.347 NM_003380
VIM
vimentin
chr1_+_119759076 0.347 NM_001166120
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr18_+_8708448 0.345


chr10_-_121286034 0.343 NM_002925
RGS10
regulator of G-protein signaling 10
chr3_-_130600931 0.339 RPL32P3
ribosomal protein L32 pseudogene 3
chr11_+_55617328 0.334 NM_001003750
OR8I2
olfactory receptor, family 8, subfamily I, member 2
chr1_+_150948146 0.331 NM_178356
LCE4A
late cornified envelope 4A
chr6_-_21631992 0.330


chrX_+_149364377 0.329 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr19_-_13808101 0.328 LOC284454
hypothetical LOC284454
chr10_-_21847126 0.327


chr17_-_15495534 0.325 TRIM16
tripartite motif containing 16
chr1_+_19807168 0.316


chr3_+_142569988 0.313 ZBTB38
zinc finger and BTB domain containing 38
chr10_-_105835525 0.313 COL17A1
collagen, type XVII, alpha 1
chr12_+_52708460 0.312 NM_004503
HOXC6
homeobox C6
chr17_-_61655915 0.310 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr3_+_100840129 0.309 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr11_+_55884266 0.305 NM_001005205
OR8J1
olfactory receptor, family 8, subfamily J, member 1
chr15_+_78520634 0.302 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr5_-_149649380 0.302 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr7_+_142053693 0.301 NM_001190487
MTRNR2L6
MT-RNR2-like 6
chr3_+_171621721 0.297 NM_001185056
CLDN11
claudin 11
chr1_-_143786993 0.296 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_41118214 0.296 NM_001010873
NM_001159726
TSPO2

translocator protein 2

chr7_-_81237162 0.295 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr19_-_16103996 0.294


chr19_-_18220009 0.293 NM_000923
PDE4C
phosphodiesterase 4C, cAMP-specific
chr1_+_173111306 0.290 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr12_+_99274987 0.289 NM_001145288
NM_139319
SLC17A8

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

chr11_+_6762823 0.287 NM_001004489
OR2AG1
olfactory receptor, family 2, subfamily AG, member 1
chr11_-_124048808 0.285 NM_170601
SIAE
sialic acid acetylesterase
chr12_+_50342814 0.284 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr11_-_124311106 0.283 HEPACAM
hepatic and glial cell adhesion molecule
chr4_+_42590038 0.278 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr1_+_149165438 0.278 NM_001145415
NM_012432
SETDB1

SET domain, bifurcated 1

chr16_-_65343012 0.277 NM_006141
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr4_+_37638450 0.276 NM_006607
PTTG2
pituitary tumor-transforming 2
chr3_-_25658829 0.274 TOP2B
topoisomerase (DNA) II beta 180kDa
chr16_+_55373241 0.273 NUP93
nucleoporin 93kDa
chr21_-_26345294 0.273


chr10_-_101831579 0.271 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr4_+_77575276 0.270 NM_020859
SHROOM3
shroom family member 3
chr7_+_28497272 0.269 CREB5
cAMP responsive element binding protein 5
chr19_-_17275083 0.268 NM_024527
ABHD8
abhydrolase domain containing 8
chr11_+_124048949 0.268 NM_017425
SPA17
sperm autoantigenic protein 17
chr12_-_6321417 0.266 NM_001065
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr13_+_100902942 0.263 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_119733062 0.262 SPPL3
signal peptide peptidase 3
chr9_-_72218098 0.259 KLF9
Kruppel-like factor 9
chr4_-_123596921 0.255 NM_000586
IL2
interleukin 2
chr5_-_149649593 0.254 NM_015981
NM_171825
CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr5_-_41249270 0.253 NM_000065
C6
complement component 6
chr10_+_99322187 0.253 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr4_+_56731117 0.253 NM_020722
KIAA1211
KIAA1211
chrX_+_117410693 0.252 WDR44
WD repeat domain 44
chr10_-_105835609 0.250 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr1_-_156635879 0.248 NM_001004475
OR10T2
olfactory receptor, family 10, subfamily T, member 2
chr3_+_189413414 0.248 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_+_117762432 0.248 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr2_+_28892366 0.248 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr12_-_74764677 0.247 NAP1L1
nucleosome assembly protein 1-like 1
chr11_+_33520348 0.246 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr1_+_156701895 0.245 NM_001004473
OR10K1
olfactory receptor, family 10, subfamily K, member 1
chr6_-_43445103 0.243 NM_014345
ZNF318
zinc finger protein 318
chr12_-_74765004 0.242 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr6_-_108252200 0.240 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr17_+_3065661 0.240 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr12_+_55201854 0.239 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr17_-_36376663 0.239 NM_213656
KRT39
keratin 39
chr11_-_111287657 0.235 NM_001885
CRYAB
crystallin, alpha B
chr10_-_106088151 0.233 ITPRIP
inositol 1,4,5-triphosphate receptor interacting protein
chr1_-_153209625 0.232 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chrX_+_104953215 0.230 NRK
Nik related kinase
chr3_+_186529376 0.229 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr4_+_146250978 0.226 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr4_+_114190233 0.222 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr8_-_19504285 0.220 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr3_-_48634192 0.220 NM_001008269
TMEM89
transmembrane protein 89
chr4_+_71096830 0.219 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr10_-_93992982 0.218 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_-_55316350 0.217 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr12_-_4624536 0.217 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr4_+_155703581 0.216 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr13_-_99983945 0.215 NM_033110
A2LD1
AIG2-like domain 1
chr12_+_79362256 0.214 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr12_+_52121699 0.213 NM_001005354
NM_018457
PRR13

proline rich 13

chr3_+_14691609 0.213 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr9_-_34116549 0.213 DCAF12
DDB1 and CUL4 associated factor 12
chr10_+_94823636 0.212 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr10_-_76488277 0.211 NM_001003892
DUPD1
dual specificity phosphatase and pro isomerase domain containing 1
chr22_+_36401558 0.210 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr3_-_50583425 0.210 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr1_+_156590109 0.210 NM_001042583
NM_001042584
NM_001042585
NM_001042586
NM_001042587
NM_001185107
NM_001185108
NM_001185110
NM_001185112
NM_001185113
NM_001185114
NM_001185115
NM_030893
CD1E












CD1e molecule












chr1_+_8928508 0.207 NM_001215
CA6
carbonic anhydrase VI
chr2_-_208702760 0.206 NM_020989
CRYGC
crystallin, gamma C
chr3_-_56673113 0.205 NM_015224
C3orf63
chromosome 3 open reading frame 63
chr9_+_124551839 0.205 NM_001004453
OR1L6
olfactory receptor, family 1, subfamily L, member 6
chr1_+_99884018 0.203 NM_017734
PALMD
palmdelphin
chr10_-_52315390 0.202 A1CF
APOBEC1 complementation factor
chr12_+_14429499 0.201 ATF7IP
activating transcription factor 7 interacting protein
chr5_-_36036883 0.200 NM_001171873
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chr9_+_115396020 0.198 NM_144489
RGS3
regulator of G-protein signaling 3
chr10_+_18280773 0.197 NM_001145195
NM_152725
SLC39A12

solute carrier family 39 (zinc transporter), member 12

chr1_+_46910086 0.196 NM_001145474
C1orf223
chromosome 1 open reading frame 223
chr1_-_156784518 0.195 NM_001005189
OR6Y1
olfactory receptor, family 6, subfamily Y, member 1
chr2_+_230989114 0.193 NM_001080391
NM_003113
SP100

SP100 nuclear antigen

chr19_+_46561688 0.193 NM_001098825
TMEM91
transmembrane protein 91
chr9_+_36159384 0.191 NM_005893
CCIN
calicin
chr2_-_177837540 0.190 NFE2L2
nuclear factor (erythroid-derived 2)-like 2
chr10_-_5035967 0.190 NM_001135241
AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr5_-_16232896 0.190 NM_001102562
MARCH11
membrane-associated ring finger (C3HC4) 11
chr1_+_147006065 0.190 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr4_+_88939725 0.188 NM_004967
IBSP
integrin-binding sialoprotein
chr9_+_106496480 0.188 NM_001004484
OR13D1
olfactory receptor, family 13, subfamily D, member 1
chr3_+_182900081 0.187 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr5_-_88155360 0.187 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr16_-_71639670 0.186 NM_006885
ZFHX3
zinc finger homeobox 3
chr6_-_24985432 0.185 NM_015864
FAM65B
family with sequence similarity 65, member B
chr1_+_84402962 0.185 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_-_19598912 0.182 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr5_-_37220702 0.181 C5orf42
chromosome 5 open reading frame 42
chr3_+_150028130 0.181 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr21_+_39745649 0.178 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr6_-_32265489 0.177 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr10_-_32707549 0.176 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr11_-_124311512 0.175 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr3_+_63859114 0.175 NM_001177387
ATXN7
ataxin 7
chr3_-_124822113 0.174 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr14_-_72523404 0.174 NM_178441
ZFYVE1
zinc finger, FYVE domain containing 1
chr2_+_230989177 0.174 SP100
SP100 nuclear antigen
chr10_+_68355797 0.173 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr17_+_24206100 0.173 NM_005702
ERAL1
Era G-protein-like 1 (E. coli)
chr7_-_23020199 0.172 FAM126A
family with sequence similarity 126, member A
chr1_-_171838802 0.167 NM_178527
SLC9A11
solute carrier family 9, member 11
chrX_+_51562894 0.167 NM_001005332
MAGED1
melanoma antigen family D, 1
chr3_+_16949585 0.166 NM_015184
PLCL2
phospholipase C-like 2
chr1_+_159943385 0.166 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr9_+_101717278 0.166 STX17
syntaxin 17
chr10_-_52315436 0.165 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr12_+_52665196 0.164 NM_017409
HOXC10
homeobox C10
chr7_+_21434818 0.164


chr2_+_230989150 0.163 SP100
SP100 nuclear antigen
chr14_-_93859394 0.161 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr3_-_52269467 0.160 WDR82
WD repeat domain 82
chr4_+_38740246 0.160 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr3_-_174341653 0.160 NM_031955
SPATA16
spermatogenesis associated 16

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.97 8.42e-05 GO:0007600 sensory perception
1.63 1.26e-04 GO:0003008 system process
2.40 1.35e-04 GO:0007608 sensory perception of smell
2.25 4.92e-04 GO:0007606 sensory perception of chemical stimulus
1.58 1.30e-02 GO:0050877 neurological system process
1.23 4.73e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.68 1.28e-04 GO:0030016 myofibril
3.47 3.36e-04 GO:0043292 contractile fiber
3.70 8.56e-04 GO:0030017 sarcomere
1.30 9.85e-04 GO:0071944 cell periphery
3.40 1.55e-03 GO:0044449 contractile fiber part
1.29 2.21e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.46 2.18e-05 GO:0004984 olfactory receptor activity
1.65 3.45e-02 GO:0004930 G-protein coupled receptor activity