Motif ID: EOMES.p2

Z-value: 0.944


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EOMESchr3_-_27739201-0.401.2e-01Click!


Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_144149794 1.024 NM_006472
 TXNIP
thioredoxin interacting protein
chr10_+_4995685 0.988 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr10_+_4995597 0.932 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr2_+_152900076 0.924 FMNL2
formin-like 2
chr2_+_171280944 0.868 SP5
Sp5 transcription factor
chr2_+_171280046 0.854 NM_001003845
 SP5
Sp5 transcription factor
chr2_+_171280182 0.836


chr6_-_29120930 0.773 NM_030903
 OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr2_+_228386800 0.699 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr4_+_8633116 0.692 NM_080819
 GPR78
G protein-coupled receptor 78
chr2_+_65070030 0.691 SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr14_+_94148466 0.651 NM_001085
 SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chrX_+_69418746 0.606 NM_001032726
 RAB41
RAB41, member RAS oncogene family
chr1_+_210848726 0.601 ATF3
activating transcription factor 3
chr3_-_71625318 0.592 FOXP1
forkhead box P1
chr20_+_55338221 0.583 NM_012444
NM_198265
 SPO11

SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)

chr11_+_122214415 0.577 NM_019604
 CRTAM
cytotoxic and regulatory T cell molecule
chr2_-_236837726 0.575 NM_212556
 ASB18
ankyrin repeat and SOCS box containing 18
chr2_-_156897286 0.573 NM_006186
 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_+_65069986 0.566 NM_003038
 SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.65 1.08e-03 GO:0007154 cell communication
1.64 3.08e-02 GO:0007267 cell-cell signaling
1.35 7.84e-06 GO:0023052 signaling
1.34 1.60e-04 GO:0007165 signal transduction
1.29 4.25e-04 GO:0051716 cellular response to stimulus
1.23 1.51e-03 GO:0032501 multicellular organismal process
1.21 5.18e-04 GO:0050896 response to stimulus
1.16 6.72e-03 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.70 7.40e-03 GO:0030054 cell junction
1.41 1.45e-04 GO:0044459 plasma membrane part
1.22 9.93e-03 GO:0071944 cell periphery
1.21 2.37e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.79 3.85e-02 GO:0015267 channel activity
1.79 4.10e-02 GO:0022803 passive transmembrane transporter activity