Motif ID: ETS1,2.p2

Z-value: 2.859


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS1chr11_-_127962662-0.476.6e-02Click!
ETS2chr21_+_39099624-0.421.1e-01Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_132759045 4.143 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr16_+_29581783 3.745 NM_001030288
SPN
sialophorin
chr1_+_18680010 3.186 NM_152375
KLHDC7A
kelch domain containing 7A
chr16_+_2145810 2.937 TRAF7
TNF receptor-associated factor 7
chr16_+_29582069 2.900 NM_003123
SPN
sialophorin
chr16_+_29582065 2.885 SPN
sialophorin
chr17_-_959007 2.832 NM_001092
ABR
active BCR-related gene
chr5_+_180582905 2.814 NM_033549
NM_201627
TRIM41

tripartite motif containing 41

chr22_+_22435207 2.768 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr1_+_24755152 2.579 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr9_+_129893948 2.570 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr2_+_113648020 2.534 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr8_+_22493928 2.380 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr22_+_17337970 2.313 DGCR5
DiGeorge syndrome critical region gene 5 (non-protein coding)
chr2_+_113648036 2.247 PSD4
pleckstrin and Sec7 domain containing 4
chr1_+_3378030 2.225 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr19_+_60589110 2.214 NM_000991
NM_001136134
NM_001136135
NM_001136136
NM_001136137
RPL28




ribosomal protein L28




chr11_+_46679140 2.204 NM_001184751
ZNF408
zinc finger protein 408
chr5_+_180582880 2.184 TRIM41
tripartite motif containing 41
chr12_+_131577229 2.146 NM_001142641
FBRSL1
fibrosin-like 1
chr16_+_2145765 2.136 NM_032271
TRAF7
TNF receptor-associated factor 7
chr11_-_3104413 2.128 OSBPL5
oxysterol binding protein-like 5
chr10_-_88707299 2.128 NM_024756
MMRN2
multimerin 2
chr11_+_2378559 2.121 TSSC4
tumor suppressing subtransferable candidate 4
chr19_+_16860807 2.081 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr8_+_144428083 2.063 GLI4
GLI family zinc finger 4
chr12_-_55920741 2.044 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr19_+_17723285 1.995 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr9_+_94766379 1.988 FGD3
FYVE, RhoGEF and PH domain containing 3
chr19_+_16860871 1.984 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr11_-_46678715 1.942 ARHGAP1
Rho GTPase activating protein 1
chr17_-_7036490 1.919


chr11_-_67528103 1.907 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr9_+_126671321 1.892 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr11_+_46678892 1.891 NM_024741
ZNF408
zinc finger protein 408
chr11_+_7574992 1.870 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_+_52451642 1.862 CCDC9
coiled-coil domain containing 9
chr3_-_130600931 1.781 RPL32P3
ribosomal protein L32 pseudogene 3
chr6_+_43507466 1.772 NM_033450
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr2_+_241156776 1.758 NM_018226
RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr17_+_4283967 1.752 NM_182538
SPNS3
spinster homolog 3 (Drosophila)
chr3_+_50259329 1.750 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr16_-_30274182 1.708 NM_006110
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr1_+_12108542 1.678 NM_152942
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr9_+_139292094 1.673 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr3_-_150533948 1.673 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr7_-_5533621 1.667 ACTB
actin, beta
chrX_+_67830204 1.651 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chrX_+_67830215 1.626 STARD8
StAR-related lipid transfer (START) domain containing 8
chr11_-_46678736 1.615 ARHGAP1
Rho GTPase activating protein 1
chr19_+_16157198 1.610 NM_014077
FAM32A
family with sequence similarity 32, member A
chrX_+_55043447 1.596 NM_014481
APEX2
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr16_+_30993223 1.556 NM_014699
ZNF646
zinc finger protein 646
chr16_+_88154582 1.554 NM_000977
NM_033251
RPL13

ribosomal protein L13

chr1_+_44208236 1.530 NM_001039589
NM_001384
DPH2

DPH2 homolog (S. cerevisiae)

chr1_+_3360880 1.526 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr22_+_37193961 1.525 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr22_+_36412277 1.523 NM_024313
NOL12
nucleolar protein 12
chr16_-_1419345 1.504 NM_001010878
C16orf91
chromosome 16 open reading frame 91
chr9_+_115396020 1.493 NM_144489
RGS3
regulator of G-protein signaling 3
chr16_+_658081 1.480 NM_138769
RHOT2
ras homolog gene family, member T2
chr9_-_138387903 1.479 CARD9
caspase recruitment domain family, member 9
chr16_-_30274064 1.470 CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr6_-_33398656 1.466 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chr11_-_46678691 1.460 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr2_+_219818428 1.459 NM_001008910
STK16
serine/threonine kinase 16
chr7_-_74953472 1.448 NM_001099415
POM121C
POM121 membrane glycoprotein C
chr1_+_6008999 1.446 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr8_+_56954946 1.442 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr9_-_129707392 1.439 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr7_+_2524022 1.438 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_-_139043035 1.431 NM_212533
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr6_+_10663934 1.430 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr15_+_79376295 1.428 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr19_+_748452 1.426 PTBP1
polypyrimidine tract binding protein 1
chr6_+_37081387 1.403 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr19_+_52451570 1.400 NM_015603
CCDC9
coiled-coil domain containing 9
chr4_+_141484046 1.394 NM_001153446
NM_001153635
NM_001153585
NM_001153690
SCOC



short coiled-coil protein



chr20_+_30501108 1.377


chr1_+_26368969 1.369 NM_015871
ZNF593
zinc finger protein 593
chr9_-_137992967 1.366 NM_016172
UBAC1
UBA domain containing 1
chr12_-_6668787 1.364 NM_001039918
NM_133476
ZNF384

zinc finger protein 384

chr10_+_71060008 1.363 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr9_-_132803809 1.363 FIBCD1
fibrinogen C domain containing 1
chr16_+_658158 1.358 RHOT2
ras homolog gene family, member T2
chr16_-_30993004 1.357 NM_024706
ZNF668
zinc finger protein 668
chr18_+_13610866 1.357 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr8_+_56954899 1.355 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr15_+_72695248 1.346 CLK3
CDC-like kinase 3
chr16_+_30993252 1.344 ZNF646
zinc finger protein 646
chr11_+_63864263 1.343 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr2_+_96566190 1.334 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr5_-_179951071 1.324 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr19_+_748448 1.320 PTBP1
polypyrimidine tract binding protein 1
chr1_-_1300680 1.319 NM_017900
AURKAIP1
aurora kinase A interacting protein 1
chr11_-_407324 1.304 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr19_+_748444 1.296 PTBP1
polypyrimidine tract binding protein 1
chr19_+_52940610 1.290 GLTSCR2
glioma tumor suppressor candidate region gene 2
chr1_+_6008956 1.281 NM_003636
NM_172130
KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr3_+_47004457 1.277 NBEAL2
neurobeachin-like 2
chr1_-_154205675 1.272 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr19_+_47079147 1.255 ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr19_+_748390 1.251 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr9_-_132804243 1.251 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr21_+_41663853 1.241 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr10_+_75174125 1.240 NM_004922
NM_198597
SEC24C

SEC24 family, member C (S. cerevisiae)

chr7_-_1562272 1.232 NM_001097620
TMEM184A
transmembrane protein 184A
chr17_+_59429442 1.225 NM_001164257
NM_001191029
NM_001191030
NM_001191031
C17orf72



chromosome 17 open reading frame 72



chr12_-_6103945 1.220 NM_000552
VWF
von Willebrand factor
chr2_-_219818360 1.216 NM_024506
GLB1L
galactosidase, beta 1-like
chr2_+_3620296 1.215 NM_024027
NM_199235
COLEC11

collectin sub-family member 11

chr16_+_1696162 1.209 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr19_+_17831670 1.208 NM_000980
RPL18A
ribosomal protein L18a
chr3_-_127303080 1.205 NM_001164475
SLC41A3
solute carrier family 41, member 3
chr10_+_75174151 1.204 SEC24C
SEC24 family, member C (S. cerevisiae)
chr18_-_75540255 1.199


chr1_+_155130146 1.198 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr11_+_303852 1.195 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr22_+_19543248 1.194 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chrX_-_40479718 1.183 NM_004229
MED14
mediator complex subunit 14
chrX_-_40479607 1.182 MED14
mediator complex subunit 14
chr22_-_19543069 1.179 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_+_60589114 1.177 RPL28
ribosomal protein L28
chr12_-_55917134 1.176 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chrX_-_73751185 1.166 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr16_-_65108605 1.162 TK2
thymidine kinase 2, mitochondrial
chr11_-_65412409 1.156 NM_004214
NM_198897
FIBP

fibroblast growth factor (acidic) intracellular binding protein

chr12_-_6668680 1.153 ZNF384
zinc finger protein 384
chr22_+_36008465 1.153 CYTH4
cytohesin 4
chr19_-_8473473 1.152 NM_032152
PRAM1
PML-RARA regulated adaptor molecule 1
chr12_-_6668880 1.151 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr19_+_19487535 1.150 NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr7_+_44050842 1.147 DBNL
drebrin-like
chr16_-_65742323 1.144 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr1_+_151596953 1.143 NM_002965
S100A9
S100 calcium binding protein A9
chrX_+_21868635 1.142 NM_004595
SMS
spermine synthase
chr5_+_180583315 1.142 TRIM41
tripartite motif containing 41
chr3_+_46894239 1.139 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr16_-_2258067 1.138 RNPS1
RNA binding protein S1, serine-rich domain
chr20_+_44180355 1.137 CD40
CD40 molecule, TNF receptor superfamily member 5
chr11_+_63498590 1.137 NM_004074
COX8A
cytochrome c oxidase subunit VIIIA (ubiquitous)
chrX_-_73751155 1.133 RLIM
ring finger protein, LIM domain interacting
chr12_+_92595281 1.128 NM_003805
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chrX_+_152699616 1.126 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr20_+_44180296 1.126 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr6_+_41714171 1.125 NM_005586
MDFI
MyoD family inhibitor
chr11_+_834445 1.123 NM_001025237
TSPAN4
tetraspanin 4
chr5_+_324700 1.122 NM_013232
PDCD6
programmed cell death 6
chr21_+_42509255 1.119 NM_207629
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr3_+_46591048 1.118 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr16_+_2593351 1.118 LOC652276
hypothetical LOC652276
chr9_-_138387926 1.116 NM_052813
NM_052814
CARD9

caspase recruitment domain family, member 9

chr17_-_42621535 1.111 CDC27
cell division cycle 27 homolog (S. cerevisiae)
chr7_-_44985175 1.109 MYO1G
myosin IG
chr17_-_74501365 1.108 CANT1
calcium activated nucleotidase 1
chr9_+_139255559 1.100 TUBB2C
tubulin, beta 2C
chr8_+_56954953 1.099 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr12_-_121780835 1.099 NM_032554
GPR81
G protein-coupled receptor 81
chrX_+_65152004 1.099


chr7_+_44050809 1.098 DBNL
drebrin-like
chr22_-_16060485 1.097 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr11_+_65414450 1.094 NM_006848
CCDC85B
coiled-coil domain containing 85B
chr19_+_47079089 1.089 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr14_-_80934523 1.083 NM_033104
STON2
stonin 2
chr1_+_15955719 1.082 FBLIM1
filamin binding LIM protein 1
chr12_+_52708460 1.071 NM_004503
HOXC6
homeobox C6
chr7_-_44985084 1.070 MYO1G
myosin IG
chr3_-_13032130 1.062


chr17_-_60208083 1.062 LOC146880
hypothetical LOC146880
chr19_+_458475 1.060 NM_033513
C19orf20
chromosome 19 open reading frame 20
chrX_-_40480005 1.060 MED14
mediator complex subunit 14
chr9_-_131444098 1.058 NM_017873
NM_177999
ASB6

ankyrin repeat and SOCS box containing 6

chr15_+_38430517 1.058 NM_001145643
PHGR1
proline/histidine/glycine-rich 1
chr17_+_7549138 1.058 NM_001406
EFNB3
ephrin-B3
chr11_+_65100074 1.055 NM_001099409
EHBP1L1
EH domain binding protein 1-like 1
chrX_-_102396704 1.054 NM_001006684
NM_153333
TCEAL8

transcription elongation factor A (SII)-like 8

chr12_+_122030825 1.052 NM_001002251
NM_001002252
NM_016638
NM_018694
ARL6IP4



ADP-ribosylation-like factor 6 interacting protein 4



chr17_-_77244034 1.048 C17orf90
chromosome 17 open reading frame 90
chr15_+_32304477 1.044 NM_016454
TMEM85
transmembrane protein 85
chr3_-_55489973 1.043 WNT5A
wingless-type MMTV integration site family, member 5A
chr16_+_30102426 1.040 CORO1A
coronin, actin binding protein, 1A
chr22_+_48740143 1.038 NM_001001852
PIM3
pim-3 oncogene
chr19_+_52940604 1.036 NM_015710
GLTSCR2
glioma tumor suppressor candidate region gene 2
chr19_+_3457264 1.036 NM_016263
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chrX_-_73751152 1.035


chr7_+_128290162 1.030 ATP6V1F
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr3_-_184756101 1.027 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_+_35031185 1.027 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr19_-_13122088 1.025 STX10
syntaxin 10
chr17_+_71065478 1.022 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr14_+_104244998 1.015 INF2
inverted formin, FH2 and WH2 domain containing
chr7_-_44985202 1.010 NM_033054
MYO1G
myosin IG
chrX_-_73751135 1.009 RLIM
ring finger protein, LIM domain interacting
chr7_+_128290092 1.007 NM_001198909
NM_004231
ATP6V1F

ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F

chr5_+_132230214 1.007 NM_014402
UQCRQ
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
chr7_-_100078270 1.006 TFR2
transferrin receptor 2
chr21_+_45184394 1.003


chr15_+_65217412 1.003 NM_001145103
SMAD3
SMAD family member 3
chr14_-_103248193 1.002 XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr19_+_60878422 0.998 EPN1
epsin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.20 1.01e-07 GO:0044260 cellular macromolecule metabolic process
1.18 1.56e-07 GO:0043170 macromolecule metabolic process
1.08 1.03e-06 GO:0009987 cellular process
1.24 1.89e-05 GO:0048518 positive regulation of biological process
1.25 1.88e-04 GO:0090304 nucleic acid metabolic process
1.27 2.13e-04 GO:0048583 regulation of response to stimulus
1.10 3.29e-04 GO:0065007 biological regulation
1.27 8.54e-04 GO:0016070 RNA metabolic process
1.18 1.02e-03 GO:0071840 cellular component organization or biogenesis
1.56 1.38e-03 GO:0016044 cellular membrane organization
1.11 1.53e-03 GO:0050794 regulation of cellular process
1.18 1.73e-03 GO:0016043 cellular component organization
1.55 1.80e-03 GO:0061024 membrane organization
1.25 2.03e-03 GO:0010467 gene expression
1.52 2.12e-03 GO:0001775 cell activation
1.22 2.15e-03 GO:0048522 positive regulation of cellular process
1.10 2.83e-03 GO:0050789 regulation of biological process
1.11 3.21e-03 GO:0044238 primary metabolic process
1.46 4.66e-03 GO:0071822 protein complex subunit organization
1.53 4.82e-03 GO:0002684 positive regulation of immune system process
1.20 5.34e-03 GO:0044267 cellular protein metabolic process
1.24 5.40e-03 GO:0043412 macromolecule modification
1.91 6.28e-03 GO:0002697 regulation of immune effector process
1.38 7.28e-03 GO:0048584 positive regulation of response to stimulus
1.29 1.04e-02 GO:0002376 immune system process
1.18 1.23e-02 GO:0019538 protein metabolic process
1.11 1.32e-02 GO:0044237 cellular metabolic process
1.36 1.35e-02 GO:0043933 macromolecular complex subunit organization
1.09 1.96e-02 GO:0008152 metabolic process
1.23 2.18e-02 GO:0006464 protein modification process
1.19 2.28e-02 GO:0006950 response to stress
1.39 2.48e-02 GO:0002682 regulation of immune system process
1.45 3.81e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.17 4.23e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.44 5.60e-03 GO:0030529 ribonucleoprotein complex
1.05 8.24e-03 GO:0005622 intracellular
1.07 9.79e-03 GO:0005737 cytoplasm
1.20 1.17e-02 GO:0005829 cytosol
1.18 1.19e-02 GO:0031974 membrane-enclosed lumen
1.21 1.23e-02 GO:0031981 nuclear lumen
1.05 1.53e-02 GO:0044424 intracellular part
1.18 2.12e-02 GO:0043233 organelle lumen
1.18 3.88e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.35e-08 GO:0005515 protein binding
1.35 1.38e-02 GO:0042802 identical protein binding