Motif ID: ETS1,2.p2

Z-value: 2.859


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS1chr11_-_127962662-0.476.6e-02Click!
ETS2chr21_+_39099624-0.421.1e-01Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_132759045 4.143 NM_198180
 QRFP
pyroglutamylated RFamide peptide
chr16_+_29581783 3.745 NM_001030288
 SPN
sialophorin
chr1_+_18680010 3.186 NM_152375
 KLHDC7A
kelch domain containing 7A
chr16_+_2145810 2.937 TRAF7
TNF receptor-associated factor 7
chr16_+_29582069 2.900 NM_003123
 SPN
sialophorin
chr16_+_29582065 2.885 SPN
sialophorin
chr17_-_959007 2.832 NM_001092
 ABR
active BCR-related gene
chr5_+_180582905 2.814 NM_033549
NM_201627
 TRIM41

tripartite motif containing 41

chr22_+_22435207 2.768 NM_182520
 C22orf15
chromosome 22 open reading frame 15
chr1_+_24755152 2.579 NM_001010980
 C1orf130
chromosome 1 open reading frame 130
chr9_+_129893948 2.570 NM_001006642
 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr2_+_113648020 2.534 NM_012455
 PSD4
pleckstrin and Sec7 domain containing 4
chr8_+_22493928 2.380 NM_176871
NM_198042
 PDLIM2

PDZ and LIM domain 2 (mystique)

chr22_+_17337970 2.313 DGCR5
DiGeorge syndrome critical region gene 5 (non-protein coding)
chr2_+_113648036 2.247 PSD4
pleckstrin and Sec7 domain containing 4
chr1_+_3378030 2.225 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr19_+_60589110 2.214 NM_000991
NM_001136134
NM_001136135
NM_001136136
NM_001136137
 RPL28




ribosomal protein L28




chr11_+_46679140 2.204 NM_001184751
 ZNF408
zinc finger protein 408
chr5_+_180582880 2.184 TRIM41
tripartite motif containing 41
chr12_+_131577229 2.146 NM_001142641
 FBRSL1
fibrosin-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
1.91 6.28e-03 GO:0002697 regulation of immune effector process
1.56 1.38e-03 GO:0016044 cellular membrane organization
1.55 1.80e-03 GO:0061024 membrane organization
1.53 4.82e-03 GO:0002684 positive regulation of immune system process
1.52 2.12e-03 GO:0001775 cell activation
1.46 4.66e-03 GO:0071822 protein complex subunit organization
1.45 3.81e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.39 2.48e-02 GO:0002682 regulation of immune system process
1.38 7.28e-03 GO:0048584 positive regulation of response to stimulus
1.36 1.35e-02 GO:0043933 macromolecular complex subunit organization
1.29 1.04e-02 GO:0002376 immune system process
1.27 2.13e-04 GO:0048583 regulation of response to stimulus
1.27 8.54e-04 GO:0016070 RNA metabolic process
1.25 1.88e-04 GO:0090304 nucleic acid metabolic process
1.25 2.03e-03 GO:0010467 gene expression
1.24 1.89e-05 GO:0048518 positive regulation of biological process
1.24 5.40e-03 GO:0043412 macromolecule modification
1.23 2.18e-02 GO:0006464 protein modification process
1.22 2.15e-03 GO:0048522 positive regulation of cellular process
1.20 1.01e-07 GO:0044260 cellular macromolecule metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.44 5.60e-03 GO:0030529 ribonucleoprotein complex
1.21 1.23e-02 GO:0031981 nuclear lumen
1.20 1.17e-02 GO:0005829 cytosol
1.18 1.19e-02 GO:0031974 membrane-enclosed lumen
1.18 2.12e-02 GO:0043233 organelle lumen
1.18 3.88e-02 GO:0044428 nuclear part
1.07 9.79e-03 GO:0005737 cytoplasm
1.05 8.24e-03 GO:0005622 intracellular
1.05 1.53e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.35 1.38e-02 GO:0042802 identical protein binding
1.14 1.35e-08 GO:0005515 protein binding