Motif ID: ATF6.p2

Z-value: 1.087


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002733-0.165.4e-01Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_46779553 1.639 NM_014011
 SOCS5
suppressor of cytokine signaling 5
chr8_+_26296439 1.618 NM_004331
 BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr12_+_70434927 1.479 RAB21
RAB21, member RAS oncogene family
chr16_+_51722285 1.422 CHD9
chromodomain helicase DNA binding protein 9
chr2_+_46779827 1.396 NM_144949
 SOCS5
suppressor of cytokine signaling 5
chr21_+_37367432 1.353 NM_001001894
 TTC3
tetratricopeptide repeat domain 3
chr12_+_70434920 1.325 NM_014999
 RAB21
RAB21, member RAS oncogene family
chr12_+_70435176 1.288 RAB21
RAB21, member RAS oncogene family
chr3_+_171167243 1.182 NM_003262
 SEC62
SEC62 homolog (S. cerevisiae)
chr20_+_46971618 1.154 NM_006420
 ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr21_-_37367259 1.118 NM_153682
 PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_+_970613 1.022 NM_178039
NM_178040
 ERC1

ELKS/RAB6-interacting/CAST family member 1

chr2_+_208103068 1.015 CREB1
cAMP responsive element binding protein 1
chr6_+_144649142 0.978 UTRN
utrophin
chr5_+_41940216 0.925 NM_175921
 C5orf51
chromosome 5 open reading frame 51
chr12_+_105873803 0.910 C12orf23
chromosome 12 open reading frame 23
chr18_+_30875297 0.899 NM_014268
 MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr18_+_7557313 0.882 NM_001105244
NM_002845
 PTPRM

protein tyrosine phosphatase, receptor type, M

chr13_+_37821964 0.875 UFM1
ubiquitin-fold modifier 1
chr3_-_120665113 0.867 NM_018266
 TMEM39A
transmembrane protein 39A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
6.74 5.27e-03 GO:0048199 vesicle targeting, to, from or within Golgi
3.29 4.85e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
2.84 4.66e-03 GO:0048193 Golgi vesicle transport
2.70 4.25e-02 GO:0006403 RNA localization
1.83 8.28e-05 GO:0046907 intracellular transport
1.83 1.54e-02 GO:0070727 cellular macromolecule localization
1.81 2.57e-02 GO:0034613 cellular protein localization
1.77 1.28e-04 GO:0045184 establishment of protein localization
1.76 2.14e-04 GO:0015031 protein transport
1.72 3.18e-05 GO:0008104 protein localization
1.69 2.34e-06 GO:0033036 macromolecule localization
1.67 1.15e-04 GO:0051649 establishment of localization in cell
1.66 1.98e-05 GO:0051641 cellular localization
1.65 3.40e-02 GO:0016192 vesicle-mediated transport
1.61 2.13e-02 GO:0006351 transcription, DNA-dependent
1.56 4.12e-02 GO:0032774 RNA biosynthetic process
1.55 3.11e-05 GO:0016070 RNA metabolic process
1.53 2.34e-05 GO:0010467 gene expression
1.44 1.05e-02 GO:0034645 cellular macromolecule biosynthetic process
1.44 1.27e-02 GO:0009059 macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
7.49 5.16e-03 GO:0030663 COPI coated vesicle membrane
6.17 2.44e-02 GO:0030137 COPI-coated vesicle
2.86 2.88e-02 GO:0042470 melanosome
2.86 2.88e-02 GO:0048770 pigment granule
2.10 5.73e-06 GO:0000139 Golgi membrane
1.88 9.58e-05 GO:0044431 Golgi apparatus part
1.65 1.59e-04 GO:0005794 Golgi apparatus
1.57 2.80e-06 GO:0012505 endomembrane system
1.56 3.73e-02 GO:0044432 endoplasmic reticulum part
1.52 5.25e-03 GO:0005783 endoplasmic reticulum
1.51 9.89e-06 GO:0031981 nuclear lumen
1.51 9.95e-04 GO:0005654 nucleoplasm
1.47 6.73e-06 GO:0031090 organelle membrane
1.46 5.09e-06 GO:0070013 intracellular organelle lumen
1.45 5.23e-06 GO:0031974 membrane-enclosed lumen
1.45 5.90e-06 GO:0043233 organelle lumen
1.45 1.34e-05 GO:0044428 nuclear part
1.36 5.21e-03 GO:0005829 cytosol
1.34 8.44e-12 GO:0044446 intracellular organelle part
1.33 2.71e-11 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.36 1.71e-02 GO:0017076 purine nucleotide binding
1.36 1.87e-02 GO:0032553 ribonucleotide binding
1.36 1.87e-02 GO:0032555 purine ribonucleotide binding
1.35 2.97e-03 GO:0000166 nucleotide binding
1.35 2.53e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.24 1.26e-08 GO:0005515 protein binding
1.10 2.62e-04 GO:0005488 binding