Motif ID: NR3C1.p2

Z-value: 0.888


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR3C1chr5_-_1427633930.758.4e-04Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_62764839 1.637 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr7_+_105390892 1.129 NM_152750
CDHR3
cadherin-related family member 3
chr15_-_68781662 1.129 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr22_+_21042091 1.046 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr22_+_21053972 1.034


chr3_-_69212192 0.809 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr1_-_156800017 0.799 NM_001160325
OR6P1
olfactory receptor, family 6, subfamily P, member 1
chr11_-_121492010 0.787 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr7_-_132131742 0.770 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_-_4924905 0.754 NM_001005329
OR51A4
olfactory receptor, family 51, subfamily A, member 4
chr21_+_30929425 0.731 NM_181616
KRTAP20-2
keratin associated protein 20-2
chr21_-_30720100 0.708 NM_181622
KRTAP13-3
keratin associated protein 13-3
chr8_+_103633023 0.700 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr3_-_112796855 0.694 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr15_-_43280664 0.685 NM_138356
SHF
Src homology 2 domain containing F
chrX_-_83644054 0.662 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr5_+_143171918 0.618 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr1_+_160868932 0.613 DDR2
discoidin domain receptor tyrosine kinase 2
chr14_-_20098929 0.590 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chrX_+_118598325 0.577 NM_181777
UBE2A
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr6_-_133008834 0.567 NM_138327
TAAR1
trace amine associated receptor 1
chr11_+_110631916 0.557 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr6_+_150731720 0.552 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr8_+_11877238 0.540 NM_001033017
DEFB135
defensin, beta 135
chr11_+_4799126 0.505 NM_001004753
OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr5_-_149304475 0.500 NM_000440
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr7_+_20621769 0.499 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr7_-_122627235 0.485 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr10_+_77212524 0.477 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr8_-_13018123 0.472 NM_001164271
DLC1
deleted in liver cancer 1
chr17_-_60439764 0.471 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr20_+_30831298 0.470 NM_175850
DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr7_+_116182676 0.470


chr1_+_67168470 0.466 NM_001077701
NM_001077704
MIER1

mesoderm induction early response 1 homolog (Xenopus laevis)

chr9_-_7789609 0.460 NM_033428
C9orf123
chromosome 9 open reading frame 123
chr9_-_41944687 0.459 MGC21881
hypothetical locus MGC21881
chr3_+_99350859 0.438 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr21_-_31049566 0.421 NM_181619
KRTAP21-1
keratin associated protein 21-1
chr1_-_184684478 0.415 NM_022576
PDC
phosducin
chrX_+_18618965 0.413 NM_006240
NM_152224
NM_152226
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr2_-_37727472 0.411 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chrX_+_105932536 0.405 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr21_+_37713076 0.404 NM_130436
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr20_+_43283423 0.390 NM_003008
SEMG2
semenogelin II
chr8_-_92122219 0.381 NM_018710
TMEM55A
transmembrane protein 55A
chr9_+_102244005 0.381 NM_001198812
C9orf3-TMEFF1
C9orf30
C9orf3-TMEFF1 readthrough
chromosome 9 open reading frame 30
chr12_-_9804682 0.380 NM_001781
CD69
CD69 molecule
chr7_-_16811131 0.379 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr14_+_19365447 0.369 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr1_-_145699308 0.366 NM_181703
GJA5
gap junction protein, alpha 5, 40kDa
chr6_+_49575629 0.364 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr6_-_89984214 0.347 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr4_+_91035025 0.338 NM_007351
MMRN1
multimerin 1
chr2_+_107969410 0.334 NM_021815
SLC5A7
solute carrier family 5 (choline transporter), member 7
chr3_+_125586241 0.321 KALRN
kalirin, RhoGEF kinase
chr4_+_114190233 0.316 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr7_-_88262966 0.315 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr1_-_181889070 0.313 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr7_-_124192265 0.312 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_22852268 0.306 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr12_-_89976261 0.306 NM_007035
KERA
keratocan
chr6_+_64289585 0.299 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr7_-_122126422 0.298 NM_139175
RNF133
ring finger protein 133
chr22_-_15453440 0.294 NM_014406
CCT8L2
chaperonin containing TCP1, subunit 8 (theta)-like 2
chr11_-_59390518 0.291 NM_001062
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr7_-_25186218 0.291 NM_138811
C7orf31
chromosome 7 open reading frame 31
chr5_-_16791346 0.290 MYO10
myosin X
chrX_+_65299157 0.289 NM_138737
HEPH
hephaestin
chr14_+_73153300 0.288 NM_001037162
ACOT6
acyl-CoA thioesterase 6
chr8_-_53484753 0.287 NM_014682
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr9_+_124355211 0.287 NM_001004457
OR1N2
olfactory receptor, family 1, subfamily N, member 2
chr16_-_70591377 0.286 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr6_-_132064233 0.284 NM_030908
OR2A4
olfactory receptor, family 2, subfamily A, member 4
chr11_+_19328846 0.284 NM_001111018
NAV2
neuron navigator 2
chr12_+_91654395 0.283 NM_001004330
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr21_+_42792810 0.282 NM_018964
SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr1_+_12325632 0.280 VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr11_+_61794205 0.280 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chrX_+_22200950 0.276 NM_152577
ZNF645
zinc finger protein 645
chr1_+_160868822 0.273 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr11_-_117628211 0.272 NM_198275
MPZL3
myelin protein zero-like 3
chr19_+_63262418 0.271 NM_001164527
NM_001164529
NM_001164530
NM_003436
NM_007134
ZNF135




zinc finger protein 135




chr4_-_20594645 0.270 KCNIP4
Kv channel interacting protein 4
chr2_-_99412694 0.269 REV1
REV1 homolog (S. cerevisiae)
chr1_-_60164912 0.268 NM_000775
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr11_+_59804634 0.263 NM_148975
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4
chr3_+_150065732 0.260 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr17_+_11726943 0.258 NM_004662
DNAH9
dynein, axonemal, heavy chain 9
chr3_+_46423682 0.257 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr1_-_94359266 0.256 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr14_-_44792354 0.252 NM_018353
MIS18BP1
MIS18 binding protein 1
chr1_-_10779291 0.252 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chrX_-_70243362 0.251 NM_001025265
CXorf65
chromosome X open reading frame 65
chr14_-_64416307 0.251 SPTB
spectrin, beta, erythrocytic
chr9_+_132579088 0.250 NM_007313
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr19_-_40317829 0.245 NM_139284
LGI4
leucine-rich repeat LGI family, member 4
chr17_-_68100537 0.244 LOC100499467
hypothetical LOC100499467
chr5_+_140541163 0.244 NM_020957
PCDHB16
protocadherin beta 16
chr9_-_124370576 0.242 NM_001004454
OR1L8
olfactory receptor, family 1, subfamily L, member 8
chrX_-_135577102 0.238 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr17_-_31441390 0.238 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr1_+_67404756 0.237 NM_144701
IL23R
interleukin 23 receptor
chr4_-_170915602 0.234 NM_017867
C4orf27
chromosome 4 open reading frame 27
chr7_-_99312591 0.232 NM_001005276
OR2AE1
olfactory receptor, family 2, subfamily AE, member 1
chr3_-_117647011 0.232 LSAMP
limbic system-associated membrane protein
chr1_-_117554999 0.230 NM_024626
VTCN1
V-set domain containing T cell activation inhibitor 1
chr4_+_35962038 0.229 NM_001170700
DTHD1
death domain containing 1
chr10_-_92670764 0.227 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr7_-_122130201 0.223 NM_198085
RNF148
ring finger protein 148
chr5_+_140690387 0.221 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr1_+_74473672 0.220 NM_015978
TNNI3K
TNNI3 interacting kinase
chr13_+_77213295 0.217 NM_144595
SLAIN1
SLAIN motif family, member 1
chr21_-_30774502 0.214 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr7_-_20223467 0.213 NM_182762
MACC1
metastasis associated in colon cancer 1
chr5_+_149867866 0.213 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr7_-_96492064 0.210 NM_005221
DLX5
distal-less homeobox 5
chr20_-_20641122 0.210 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr1_-_166779825 0.210 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr9_-_106401514 0.209 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chrX_-_100434700 0.209 NM_024885
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr10_+_116571485 0.208 NM_001135051
NM_020940
FAM160B1

family with sequence similarity 160, member B1

chr4_-_155731288 0.207 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr12_+_6925997 0.205 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_-_67668654 0.204 SERBP1
SERPINE1 mRNA binding protein 1
chr18_-_51219880 0.204 TCF4
transcription factor 4
chr5_+_55098469 0.204 NM_001166534
DDX4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr6_-_127882192 0.203 NM_001012279
C6orf174
chromosome 6 open reading frame 174
chr5_+_147628567 0.203 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr19_-_62680703 0.203 NM_001024596
NM_001144068
ZNF772

zinc finger protein 772

chr4_-_95482994 0.202 NM_014485
HPGDS
hematopoietic prostaglandin D synthase
chrX_+_123062143 0.202 STAG2
stromal antigen 2
chr2_-_233586145 0.201 NGEF
neuronal guanine nucleotide exchange factor
chr9_+_96561750 0.201 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr1_-_158759606 0.201 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr4_+_72423633 0.200 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr1_-_219977424 0.199 NM_144728
DUSP10
dual specificity phosphatase 10
chr1_-_151296611 0.197 NM_005988
SPRR2A
small proline-rich protein 2A
chr5_+_171553780 0.194 NM_001171183
EFCAB9
EF-hand calcium binding domain 9
chr6_-_132952517 0.194 NM_003967
TAAR5
trace amine associated receptor 5
chr6_-_152681171 0.194 NM_015293
SYNE1
spectrin repeat containing, nuclear envelope 1
chr7_-_17946627 0.193 NM_015132
SNX13
sorting nexin 13
chrX_-_101613387 0.192 NM_017809
NM_001099686
NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr11_-_57752923 0.192 NM_001004471
OR10Q1
olfactory receptor, family 10, subfamily Q, member 1
chr20_+_51235228 0.192 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr14_+_85069217 0.189


chr7_-_97339616 0.188 ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr16_+_24475129 0.187 RBBP6
retinoblastoma binding protein 6
chr2_-_233586164 0.187 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr13_+_45174446 0.185 NM_152719
SPERT
spermatid associated
chr3_-_150858274 0.183 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr1_+_144188375 0.182 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr7_+_128795280 0.181 AHCYL2
adenosylhomocysteinase-like 2
chr1_-_157950898 0.181 NM_000567
CRP
C-reactive protein, pentraxin-related
chr7_+_93388951 0.180 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chrX_+_115215985 0.180 NM_000686
AGTR2
angiotensin II receptor, type 2
chr7_-_126819953 0.180 NM_176814
ZNF800
zinc finger protein 800
chr1_+_111571803 0.179 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr14_+_99309688 0.178 EML1
echinoderm microtubule associated protein like 1
chr12_-_55730125 0.177 NM_005379
MYO1A
myosin IA
chr20_-_18425811 0.177 NM_006606
RBBP9
retinoblastoma binding protein 9
chrX_-_23955223 0.176 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr18_+_74957475 0.176


chrX_+_65299352 0.175 HEPH
hephaestin
chr12_+_6926014 0.174 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr10_+_83627422 0.174 NM_001165973
NRG3
neuregulin 3
chrX_+_49223101 0.173 NM_001098405
GAGE12F
GAGE3
GAGE4
GAGE5
GAGE7
G antigen 12F
G antigen 3
G antigen 4
G antigen 5
G antigen 7
chr15_-_31999815 0.173


chr7_-_86526880 0.173 NM_001142749
KIAA1324L
KIAA1324-like
chr6_-_52736231 0.173 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr14_+_67238355 0.171 NM_152443
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr19_-_9470243 0.166 NM_152476
ZNF560
zinc finger protein 560
chr21_-_31041390 0.166 NM_181617
KRTAP21-2
keratin associated protein 21-2
chr4_-_10295412 0.165 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr1_-_177106702 0.165 NM_004673
ANGPTL1
angiopoietin-like 1
chr5_-_95044415 0.163 NM_031952
SPATA9
spermatogenesis associated 9
chr21_-_30614477 0.163 NM_203405
KRTAP26-1
keratin associated protein 26-1
chr12_+_15017222 0.162 NM_006205
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr1_-_159546348 0.160 NM_000530
MPZ
myelin protein zero
chr1_+_62835759 0.160 NM_014495
ANGPTL3
angiopoietin-like 3
chr11_-_26700121 0.160 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr11_+_57738792 0.158 NM_001004458
OR1S1
olfactory receptor, family 1, subfamily S, member 1
chr12_+_20739555 0.158 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr4_+_147779492 0.158 NM_004575
POU4F2
POU class 4 homeobox 2
chr10_+_91142301 0.158 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr19_-_47724365 0.158 NM_001024912
NM_001184813
NM_001184815
NM_001184816
NM_001712
CEACAM1




carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)




chr19_-_40317450 0.158 LGI4
leucine-rich repeat LGI family, member 4
chr17_-_32730804 0.157 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr9_+_6205804 0.156 IL33
interleukin 33
chr19_-_9087438 0.156 NM_001005192
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr9_+_128764324 0.155 NM_001190728
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr14_+_80491461 0.155 NM_000369
NM_001018036
NM_001142626
TSHR


thyroid stimulating hormone receptor


chrX_-_48156287 0.155 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr1_+_164063684 0.153 UCK2
uridine-cytidine kinase 2
chr2_-_36929520 0.152 STRN
striatin, calmodulin binding protein
chr15_+_57696016 0.152 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_-_67668686 0.151 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr7_+_123036312 0.151 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr1_-_35692668 0.150 KIAA0319L
KIAA0319-like
chr1_-_149586298 0.149 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chrX_-_55204259 0.149 NM_001166703
FAM104B
family with sequence similarity 104, member B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.15 2.20e-09 GO:0007608 sensory perception of smell
2.88 3.58e-08 GO:0007606 sensory perception of chemical stimulus
2.20 2.41e-06 GO:0007600 sensory perception
1.67 1.75e-04 GO:0003008 system process
1.74 5.10e-04 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 3.39e-03 GO:0005886 plasma membrane
1.29 5.81e-03 GO:0071944 cell periphery
1.77 1.09e-02 GO:0005615 extracellular space
2.77 2.37e-02 GO:0005882 intermediate filament

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.30 9.49e-11 GO:0004984 olfactory receptor activity
2.09 6.10e-06 GO:0004930 G-protein coupled receptor activity
1.66 2.45e-03 GO:0004888 transmembrane receptor activity
1.47 3.42e-02 GO:0004872 receptor activity
6.19 3.64e-02 GO:0030545 receptor regulator activity
7.33 4.22e-02 GO:0004364 glutathione transferase activity