Motif ID: NANOG.p2

Z-value: 1.351


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_7833261-0.361.7e-01Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_169713458 2.367 NM_001034838
 KCNIP1
Kv channel interacting protein 1
chr7_-_13992351 2.340 NM_001163150
NM_001163151
NM_001163152
 ETV1


ets variant 1


chr6_+_34314545 2.238 NM_145905
 HMGA1
high mobility group AT-hook 1
chr1_+_154449389 2.068 NM_007221
 PMF1-BGLAP
PMF1
PMF1-BGLAP read-through transcript
polyamine-modulated factor 1
chr3_-_12916547 1.989 IQSEC1
IQ motif and Sec7 domain 1
chr11_-_2149591 1.827 NM_000360
NM_199292
NM_199293
 TH


tyrosine hydroxylase


chr1_+_180836050 1.612


chr12_-_51114372 1.612 NM_004693
 KRT75
keratin 75
chr19_-_46504831 1.511


chr3_+_130730171 1.480 NM_000539
 RHO
rhodopsin
chr7_-_25234582 1.470 NM_022150
 NPVF
neuropeptide VF precursor
chr6_+_44076281 1.464 NM_001171992
NM_153246
 C6orf223

chromosome 6 open reading frame 223

chr1_+_100776280 1.441 NM_022049
 GPR88
G protein-coupled receptor 88
chr12_-_55614311 1.384 NM_148897
 SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr7_-_96471544 1.343 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr9_+_117955890 1.337 NM_002581
 PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr7_+_116238309 1.321 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr9_-_132759045 1.306 NM_198180
 QRFP
pyroglutamylated RFamide peptide
chr12_-_120725210 1.293 LOC338799
hypothetical LOC338799
chr18_+_18989786 1.264 NM_138375
 CABLES1
Cdk5 and Abl enzyme substrate 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
3.21 1.53e-02 GO:0048562 embryonic organ morphogenesis
2.87 2.96e-02 GO:0007517 muscle organ development
2.52 7.48e-03 GO:0051093 negative regulation of developmental process
2.40 3.90e-02 GO:0060284 regulation of cell development
2.37 2.31e-05 GO:0009887 organ morphogenesis
2.28 2.04e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.17 2.09e-04 GO:0045595 regulation of cell differentiation
1.91 3.02e-03 GO:0009888 tissue development
1.87 4.22e-03 GO:0050793 regulation of developmental process
1.80 2.07e-07 GO:0048513 organ development
1.67 2.29e-03 GO:0009653 anatomical structure morphogenesis
1.63 9.54e-08 GO:0048731 system development
1.61 1.50e-08 GO:0048856 anatomical structure development
1.59 2.83e-02 GO:0007399 nervous system development
1.58 1.01e-08 GO:0007275 multicellular organismal development
1.56 3.83e-09 GO:0032502 developmental process
1.49 1.91e-02 GO:0048523 negative regulation of cellular process
1.48 8.09e-11 GO:0032501 multicellular organismal process
1.46 1.78e-02 GO:0048519 negative regulation of biological process
1.22 6.72e-03 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
12.58 4.82e-02 GO:0005614 interstitial matrix
3.77 2.30e-02 GO:0045095 keratin filament
2.48 1.61e-03 GO:0005578 proteinaceous extracellular matrix
2.44 3.73e-04 GO:0031012 extracellular matrix
2.11 1.49e-02 GO:0044463 cell projection part
1.73 2.86e-03 GO:0044421 extracellular region part
1.62 1.19e-05 GO:0005576 extracellular region
1.48 2.07e-03 GO:0044459 plasma membrane part
1.39 1.45e-05 GO:0071944 cell periphery
1.39 1.85e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.86 1.23e-02 GO:0043565 sequence-specific DNA binding
1.72 7.11e-03 GO:0001071 nucleic acid binding transcription factor activity
1.72 7.11e-03 GO:0003700 sequence-specific DNA binding transcription factor activity