Motif ID: CREB1.p2

Z-value: 1.883


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081030010.302.5e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_12652427 2.949 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_+_171558188 2.455 SKIL
SKI-like oncogene
chr3_+_171558215 2.404 SKIL
SKI-like oncogene
chr3_+_171558143 2.120 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr10_+_85889164 2.082 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr10_+_49184658 1.986 MAPK8
mitogen-activated protein kinase 8
chr17_+_15843832 1.797 TTC19
tetratricopeptide repeat domain 19
chr1_+_220857774 1.721 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr3_+_43303005 1.683 NM_001100594
NM_017719
SNRK

SNF related kinase

chr2_+_192251105 1.636 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr5_+_41940216 1.595 NM_175921
C5orf51
chromosome 5 open reading frame 51
chr7_+_120378052 1.570 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr4_+_144654005 1.523 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr8_-_17148637 1.518 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr12_+_970613 1.510 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr4_-_120595218 1.452


chr9_+_113433364 1.367 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr3_+_44746101 1.338 NM_145044
ZNF501
zinc finger protein 501
chr4_+_144654526 1.302


chr21_+_43903803 1.273 NM_015056
RRP1B
ribosomal RNA processing 1 homolog B (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
4.17 3.49e-02 GO:0006888 ER to Golgi vesicle-mediated transport
2.11 4.65e-03 GO:0008380 RNA splicing
1.97 4.66e-03 GO:0006397 mRNA processing
1.92 3.64e-04 GO:0044265 cellular macromolecule catabolic process
1.91 2.20e-05 GO:0006396 RNA processing
1.91 1.79e-03 GO:0006325 chromatin organization
1.89 6.63e-03 GO:0000279 M phase
1.88 1.06e-04 GO:0051276 chromosome organization
1.86 1.33e-03 GO:0016071 mRNA metabolic process
1.79 5.55e-05 GO:0046907 intracellular transport
1.77 5.80e-05 GO:0022402 cell cycle process
1.75 5.31e-03 GO:0009057 macromolecule catabolic process
1.72 6.54e-06 GO:0007049 cell cycle
1.69 7.30e-03 GO:0022403 cell cycle phase
1.69 4.47e-02 GO:0000278 mitotic cell cycle
1.68 1.15e-03 GO:0033554 cellular response to stress
1.65 1.58e-03 GO:0045184 establishment of protein localization
1.63 4.31e-03 GO:0015031 protein transport
1.60 3.43e-07 GO:0006996 organelle organization
1.60 2.58e-04 GO:0044248 cellular catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
7.39 2.17e-02 GO:0000242 pericentriolar material
3.97 1.07e-02 GO:0008287 protein serine/threonine phosphatase complex
2.03 7.08e-04 GO:0005815 microtubule organizing center
2.02 3.36e-02 GO:0005813 centrosome
1.95 2.45e-05 GO:0005730 nucleolus
1.74 8.77e-10 GO:0005654 nucleoplasm
1.72 3.63e-03 GO:0005694 chromosome
1.71 1.83e-13 GO:0031981 nuclear lumen
1.71 2.17e-02 GO:0044427 chromosomal part
1.69 5.12e-04 GO:0044451 nucleoplasm part
1.68 1.28e-03 GO:0015630 microtubule cytoskeleton
1.66 2.99e-02 GO:0030529 ribonucleoprotein complex
1.64 3.04e-13 GO:0044428 nuclear part
1.61 1.97e-12 GO:0070013 intracellular organelle lumen
1.58 1.10e-11 GO:0043233 organelle lumen
1.56 3.94e-11 GO:0031974 membrane-enclosed lumen
1.37 4.06e-16 GO:0005634 nucleus
1.37 3.22e-08 GO:0032991 macromolecular complex
1.36 2.25e-15 GO:0044446 intracellular organelle part
1.35 1.07e-14 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
3.70 3.36e-02 GO:0004722 protein serine/threonine phosphatase activity
2.30 2.27e-02 GO:0004721 phosphoprotein phosphatase activity
1.45 9.64e-04 GO:0005524 ATP binding
1.43 2.02e-03 GO:0030554 adenyl nucleotide binding
1.42 2.66e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.42 2.31e-03 GO:0032559 adenyl ribonucleotide binding
1.40 7.48e-04 GO:0017076 purine nucleotide binding
1.40 7.95e-04 GO:0032553 ribonucleotide binding
1.40 7.95e-04 GO:0032555 purine ribonucleotide binding
1.37 3.79e-07 GO:0003676 nucleic acid binding
1.36 6.50e-04 GO:0000166 nucleotide binding
1.32 6.49e-03 GO:0003677 DNA binding
1.22 8.31e-05 GO:0003824 catalytic activity
1.19 5.95e-06 GO:0005515 protein binding
1.10 3.10e-05 GO:0005488 binding