Motif ID: ESR1.p2

Z-value: 2.517


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESR1chr6_+_152053323-0.467.2e-02Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_1236766 4.270 NM_001405
 EFNA2
ephrin-A2
chr21_-_45786709 3.351 NM_194255
 SLC19A1
solute carrier family 19 (folate transporter), member 1
chr16_+_550394 2.604 NM_145270
 C16orf11
chromosome 16 open reading frame 11
chr16_+_559970 2.524 NM_004204
NM_148920
 PIGQ

phosphatidylinositol glycan anchor biosynthesis, class Q

chr19_-_3927523 2.482 EEF2
eukaryotic translation elongation factor 2
chr3_-_135852514 2.432 NM_178554
 KY
kyphoscoliosis peptidase
chr16_+_84204424 2.288 NM_014615
 KIAA0182
KIAA0182
chr1_+_178466064 2.242 NM_033343
 LHX4
LIM homeobox 4
chr19_+_3457264 2.227 NM_016263
 FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr9_+_139202874 2.212 NM_003731
 SSNA1
Sjogren syndrome nuclear autoantigen 1
chr14_+_105063975 2.131 NM_025268
 TMEM121
transmembrane protein 121
chr1_+_1256585 2.099 NM_152228
 TAS1R3
taste receptor, type 1, member 3
chr9_+_137532294 2.046 NM_016034
 MRPS2
mitochondrial ribosomal protein S2
chr8_+_144428083 2.036 GLI4
GLI family zinc finger 4
chr19_+_590878 2.027 NM_020637
 FGF22
fibroblast growth factor 22
chr7_+_1536847 1.985 NM_002360
 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr20_-_60415729 1.977 NM_031215
 CABLES2
Cdk5 and Abl enzyme substrate 2
chr19_+_10392128 1.920 NM_001111307
 PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_62433061 1.841 NM_001164835
NM_019079
 L1TD1

LINE-1 type transposase domain containing 1

chr9_-_139202855 1.822 NM_013366
 ANAPC2
anaphase promoting complex subunit 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.94 1.54e-02 GO:0046578 regulation of Ras protein signal transduction
1.43 3.18e-04 GO:0009966 regulation of signal transduction
1.43 4.29e-02 GO:0042127 regulation of cell proliferation
1.41 1.90e-04 GO:0023051 regulation of signaling
1.28 3.97e-02 GO:0048523 negative regulation of cellular process
1.27 2.26e-02 GO:0048519 negative regulation of biological process
1.21 1.43e-02 GO:0023052 signaling
1.17 2.53e-05 GO:0050794 regulation of cellular process
1.15 1.43e-05 GO:0065007 biological regulation
1.15 2.23e-04 GO:0050789 regulation of biological process
1.08 6.44e-03 GO:0009987 cellular process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.83 1.54e-02 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.55 2.19e-02 GO:0019199 transmembrane receptor protein kinase activity
2.35 1.30e-03 GO:0004713 protein tyrosine kinase activity
1.61 1.36e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.59 3.04e-02 GO:0030695 GTPase regulator activity
1.51 2.50e-02 GO:0004672 protein kinase activity
1.49 1.23e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.45 2.76e-02 GO:0016301 kinase activity
1.16 2.00e-06 GO:0005515 protein binding
1.08 2.61e-04 GO:0005488 binding