Motif ID: NR1H4.p2

Z-value: 2.165


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
NR1H4 9971 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR1H4chr12_+_99391870-0.495.2e-02Click!


Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_531666 5.207 BSG
basigin (Ok blood group)
chr1_+_93830169 3.733 LOC100129046
hypothetical LOC100129046
chr1_+_93830106 3.484 LOC100129046
hypothetical LOC100129046
chr1_-_47468029 2.349 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr1_+_33003847 2.113 KIAA1522
KIAA1522
chr1_+_31814672 2.062 NM_022164
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr8_+_145692916 2.043 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr17_-_29930431 2.039 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr1_+_31814712 1.987 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_31814709 1.983 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr20_-_61933012 1.974 ZBTB46
zinc finger and BTB domain containing 46
chr3_-_127719283 1.946 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr3_+_52803823 1.759 NM_002217
ITIH3
inter-alpha (globulin) inhibitor H3
chr17_+_71975224 1.736 NM_001088
AANAT
aralkylamine N-acetyltransferase
chr1_+_33003814 1.723 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr16_+_87765661 1.701 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr10_+_46413551 1.660 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr19_-_3920736 1.552 NM_001348
DAPK3
death-associated protein kinase 3
chr12_+_55909622 1.532 NM_001166356
NM_005412
SHMT2

serine hydroxymethyltransferase 2 (mitochondrial)

chr17_-_70367479 1.482 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr19_-_53941835 1.465 NM_182575
IZUMO1
izumo sperm-egg fusion 1
chrX_+_102918453 1.441 PLP1
proteolipid protein 1
chr6_+_43845875 1.408 VEGFA
vascular endothelial growth factor A
chrX_-_106033202 1.398 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr1_+_29113589 1.384 NM_001166006
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr19_+_627346 1.348 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr17_-_40674883 1.333


chr17_+_18221803 1.322 NM_001145127
EVPLL
envoplakin-like
chr7_+_150376537 1.302 NM_004769
NM_020321
NM_020322
ACCN3


amiloride-sensitive cation channel 3


chr19_+_59657440 1.276


chr6_+_43846735 1.248 VEGFA
vascular endothelial growth factor A
chr14_-_73962557 1.241 NM_001105579
TMEM90A
transmembrane protein 90A
chr17_-_77647505 1.236 FASN
fatty acid synthase
chr9_-_137531517 1.231 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr1_+_109969571 1.224 NM_203404
AMPD2
adenosine monophosphate deaminase 2
chr1_+_152560179 1.207 NM_080429
AQP10
aquaporin 10
chr9_+_137577805 1.205 NM_014582
OBP2A
odorant binding protein 2A
chr1_+_559618 1.196


chr14_-_104507862 1.185 AHNAK2
AHNAK nucleoprotein 2
chr6_+_43846155 1.180 VEGFA
vascular endothelial growth factor A
chrX_+_152454773 1.137 NM_001001344
NM_021949
ATP2B3

ATPase, Ca++ transporting, plasma membrane 3

chr16_-_3025542 1.115 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr11_-_64133908 1.113


chr6_+_31731647 1.113 NM_019101
APOM
apolipoprotein M
chr6_+_31731667 1.107 APOM
apolipoprotein M
chr8_-_143692814 1.102 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr3_+_46717826 1.096 NM_147196
TMIE
transmembrane inner ear
chr12_-_7172641 1.095 NM_031491
RBP5
retinol binding protein 5, cellular
chr1_+_26744893 1.081 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr5_+_145297490 1.070 SH3RF2
SH3 domain containing ring finger 2
chr17_+_38430773 1.070 NM_005440
RND2
Rho family GTPase 2
chr6_-_169392771 1.057


chr5_+_159589014 1.057 NM_001445
FABP6
fatty acid binding protein 6, ileal
chr9_-_34554800 1.056 CNTFR
ciliary neurotrophic factor receptor
chr16_+_1979959 1.051 NM_004209
SYNGR3
synaptogyrin 3
chr2_+_241213334 1.047 NM_005301
GPR35
G protein-coupled receptor 35
chr6_+_43846372 1.044 VEGFA
vascular endothelial growth factor A
chr5_+_145296313 1.043 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr6_+_43845915 1.040 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_003376
VEGFA















vascular endothelial growth factor A















chrX_+_69371229 1.038 NM_001013579
AWAT1
acyl-CoA wax alcohol acyltransferase 1
chr10_-_50269912 1.035 NM_001080520
DRGX
dorsal root ganglia homeobox
chr1_+_203179976 1.035 NM_001160331
NFASC
neurofascin
chr17_+_71097147 1.023 MYO15B
myosin XVB pseudogene
chr19_+_5641307 1.020 RPL36
ribosomal protein L36
chr11_-_64266916 1.017


chr14_-_104330982 1.014 NM_005163
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr17_-_35017650 1.009 NEUROD2
neurogenic differentiation 2
chr21_+_41663853 0.993 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chrX_+_102918409 0.984 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr17_-_77092831 0.971 ACTG1
actin, gamma 1
chr19_-_63556632 0.971 NM_130786
A1BG
alpha-1-B glycoprotein
chr2_-_241270982 0.967 NM_001102467
AQP12A
AQP12B
aquaporin 12A
aquaporin 12B
chr12_-_56200547 0.965 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr1_+_968522 0.961 AGRN
agrin
chr7_+_49783774 0.958 NM_198570
VWC2
von Willebrand factor C domain containing 2
chr12_+_56299959 0.942 NM_133489
SLC26A10
solute carrier family 26, member 10
chr16_-_1369613 0.936 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr5_+_131621287 0.934 PDLIM4
PDZ and LIM domain 4
chr17_+_18588050 0.929 NM_031456
FBXW10
CDRT1
F-box and WD repeat domain containing 10
CMT1A duplicated region transcript 1
chr1_+_1324762 0.927 LOC148413
hypothetical LOC148413
chr16_+_65552600 0.923 NM_001185177
NM_024922
CES3

carboxylesterase 3

chr4_-_1185144 0.922 LOC100130872
hypothetical LOC100130872
chrX_+_107174855 0.920 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr20_-_3592045 0.914 NM_022139
NM_145762
GFRA4

GDNF family receptor alpha 4

chrX_+_106030049 0.904 NM_001171092
CLDN2
claudin 2
chr1_-_36562341 0.899 NM_018166
FAM176B
family with sequence similarity 176, member B
chr1_+_45565126 0.896 NM_032756
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr17_-_23903772 0.896 NM_005148
NM_054035
UNC119

unc-119 homolog (C. elegans)

chr1_-_151852128 0.894 NM_080388
S100A16
S100 calcium binding protein A16
chr1_-_1324511 0.892 NM_001039577
NM_030937
CCNL2

cyclin L2

chr19_+_5641332 0.885 NM_015414
RPL36
ribosomal protein L36
chr11_+_63060848 0.885 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr22_-_43040063 0.883 NM_001099294
KIAA1644
KIAA1644
chr22_+_29151651 0.882 NM_001003704
NM_016498
MTFP1

mitochondrial fission process 1

chr19_+_5641270 0.879 NM_033643
RPL36
ribosomal protein L36
chr22_+_18085891 0.877 SEPT5
septin 5
chr22_+_23309717 0.869 NM_013430
GGT1
gamma-glutamyltransferase 1
chr22_+_28446288 0.865 NM_182527
CABP7
calcium binding protein 7
chr19_+_40895669 0.862 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr12_+_50592379 0.858 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr5_+_131621276 0.857 PDLIM4
PDZ and LIM domain 4
chr5_+_149549712 0.856 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr14_-_105163301 0.855 IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr1_+_26744929 0.851 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chrX_+_67965517 0.845 NM_004429
EFNB1
ephrin-B1
chr1_-_25128951 0.842 RUNX3
runt-related transcription factor 3
chr3_-_127810087 0.837 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr17_-_23903704 0.834 UNC119
unc-119 homolog (C. elegans)
chr5_+_133478252 0.830 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr1_-_25129354 0.823 NM_004350
RUNX3
runt-related transcription factor 3
chr19_+_17691283 0.822 MAP1S
microtubule-associated protein 1S
chr11_+_67007080 0.822 NM_003977
AIP
aryl hydrocarbon receptor interacting protein
chr22_+_18085990 0.819 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr3_-_48607596 0.810 NM_000094
COL7A1
collagen, type VII, alpha 1
chr2_-_182253457 0.807 NM_002500
NEUROD1
neurogenic differentiation 1
chr17_-_35017691 0.804 NM_006160
NEUROD2
neurogenic differentiation 2
chr17_+_75776193 0.800 NM_052819
CARD14
caspase recruitment domain family, member 14
chr17_+_73676219 0.799 NM_004710
SYNGR2
synaptogyrin 2
chr19_-_50355247 0.797 NM_198478
NKPD1
NTPase, KAP family P-loop domain containing 1
chr2_-_218575922 0.796 TNS1
tensin 1
chr16_-_65775326 0.794 NM_001040715
KIAA0895L
KIAA0895-like
chr11_+_66381451 0.784 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr16_+_66131247 0.781 FAM65A
family with sequence similarity 65, member A
chr4_-_69852090 0.780 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_+_29086156 0.779 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr3_-_58627509 0.779 NM_138805
FAM3D
family with sequence similarity 3, member D
chrX_+_65152004 0.779


chr1_+_46541913 0.772 NM_006004
UQCRH
ubiquinol-cytochrome c reductase hinge protein
chr22_+_19651446 0.769 NM_001146288
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr11_+_74539679 0.767 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr17_+_45706786 0.765 NM_153229
TMEM92
transmembrane protein 92
chr16_-_2276875 0.763


chr9_+_35032222 0.763 NM_001040410
NM_203299
C9orf131

chromosome 9 open reading frame 131

chr16_+_30102231 0.763 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr9_+_126094388 0.761 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr15_+_72695248 0.757 CLK3
CDC-like kinase 3
chr1_+_15637521 0.753 NM_007272
CTRC
chymotrypsin C (caldecrin)
chr1_+_29086206 0.752 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chrX_+_102918089 0.750 NM_001128834
PLP1
proteolipid protein 1
chr7_+_2638156 0.748 TTYH3
tweety homolog 3 (Drosophila)
chr16_+_11669736 0.745 NM_003498
SNN
stannin
chr5_-_177355848 0.743 NM_006261
PROP1
PROP paired-like homeobox 1
chrX_-_21686079 0.739 NM_014332
SMPX
small muscle protein, X-linked
chr11_+_67007155 0.737 AIP
aryl hydrocarbon receptor interacting protein
chr19_+_17691302 0.735 NM_018174
MAP1S
microtubule-associated protein 1S
chr1_+_20338405 0.735 NM_022819
PLA2G2F
phospholipase A2, group IIF
chr1_+_17121012 0.722 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr1_+_12046020 0.720 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr19_-_47638890 0.717 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr11_-_62136778 0.716 NM_153265
EML3
echinoderm microtubule associated protein like 3
chr11_+_118561375 0.714 NM_001168468
NM_024791
PDZD3

PDZ domain containing 3

chr5_+_131621230 0.712 NM_001131027
NM_003687
PDLIM4

PDZ and LIM domain 4

chr7_+_2638108 0.705 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr17_-_76827370 0.702 C17orf56
chromosome 17 open reading frame 56
chr11_+_62136788 0.695 NM_000327
ROM1
retinal outer segment membrane protein 1
chr19_-_16497213 0.692 CHERP
calcium homeostasis endoplasmic reticulum protein
chr10_+_71060008 0.692 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr6_+_41622267 0.690 FOXP4
forkhead box P4
chr11_+_64114857 0.687 NM_144585
NM_153378
SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

chr15_+_70734091 0.685 NM_018652
GOLGA6A
GOLGA6B
golgin A6 family, member A
golgin A6 family, member B
chr22_+_17337970 0.683 DGCR5
DiGeorge syndrome critical region gene 5 (non-protein coding)
chr19_+_10424581 0.683 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr16_+_30102426 0.678 CORO1A
coronin, actin binding protein, 1A
chr22_-_37211467 0.672 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr1_+_16131633 0.671


chr1_-_39871226 0.669 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr15_-_38185578 0.666 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr7_+_45899080 0.666 IGFBP1
insulin-like growth factor binding protein 1
chr1_+_32512298 0.665 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr17_-_42250961 0.662 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr13_+_113587674 0.660 GAS6
growth arrest-specific 6
chrX_+_151991474 0.659 NM_001170944
NM_032882
LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr16_+_29892714 0.652 NM_004783
NM_016151
TAOK2

TAO kinase 2

chr19_+_40299058 0.652 FXYD3
FXYD domain containing ion transport regulator 3
chr1_-_154205675 0.648 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr17_+_71229191 0.646 ITGB4
integrin, beta 4
chr1_-_77457664 0.644 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr16_+_670426 0.644 STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr11_+_65140207 0.644 NM_032223
PCNXL3
pecanex-like 3 (Drosophila)
chr17_-_7047285 0.641 DLG4
discs, large homolog 4 (Drosophila)
chr1_+_32485404 0.638 NM_032648
FAM167B
family with sequence similarity 167, member B
chr16_+_273118 0.638 NM_006849
PDIA2
protein disulfide isomerase family A, member 2
chr17_-_43390108 0.637 NM_024320
PRR15L
proline rich 15-like
chrX_+_151633730 0.636 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr17_+_76827699 0.630 NM_001086521
C17orf89
chromosome 17 open reading frame 89
chr12_-_51514328 0.630 NM_175834
KRT79
keratin 79
chr1_-_25129305 0.628 RUNX3
runt-related transcription factor 3
chr20_+_30192968 0.626 TM9SF4
transmembrane 9 superfamily protein member 4
chr6_-_33016561 0.624 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr18_-_65775139 0.623 NM_006566
CD226
CD226 molecule
chr17_-_15463742 0.621 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr1_+_160618143 0.618 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr3_-_46693902 0.617 NM_182775
ALS2CL
ALS2 C-terminal like
chr1_-_16812274 0.612 NM_017940
NBPF1
neuroblastoma breakpoint family, member 1
chr17_+_77261447 0.611 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr11_-_3649120 0.608 NM_020402
CHRNA10
cholinergic receptor, nicotinic, alpha 10
chr6_+_44234525 0.605 NM_007058
CAPN11
calpain 11
chr2_+_27225362 0.603 NM_175769
TCF23
transcription factor 23
chr6_+_42231121 0.603 NM_000409
GUCA1A
guanylate cyclase activator 1A (retina)
chr9_+_137532294 0.603 NM_016034
MRPS2
mitochondrial ribosomal protein S2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 9.90e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.17 1.60e-03 GO:0003823 antigen binding