Motif ID: AR.p2

Z-value: 1.116


Transcription factors associated with AR.p2:

Gene SymbolEntrez IDGene Name
AR 367 androgen receptor



Activity profile for motif AR.p2.

activity profile for motif AR.p2


Sorted Z-values histogram for motif AR.p2

Sorted Z-values for motif AR.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AR.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_149778815 3.014 GIMAP8
GTPase, IMAP family member 8
chr7_+_149778869 2.864 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr3_+_52254782 2.075 PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr1_-_154727014 1.798 MEF2D
myocyte enhancer factor 2D
chr2_+_134728299 1.346 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr1_+_149395728 1.165 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr12_+_111900650 1.164 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr1_-_149004852 1.161 CTSS
cathepsin S
chr1_-_200396328 0.948 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr2_-_231498184 0.834 NM_005683
GPR55
G protein-coupled receptor 55
chr1_-_149004879 0.800 CTSS
cathepsin S
chr19_+_17499064 0.776 FAM129C
family with sequence similarity 129, member C
chr10_+_70517823 0.715 NM_002727
SRGN
serglycin
chr1_-_149004916 0.711 NM_004079
CTSS
cathepsin S
chr4_+_186301410 0.704 NM_001151
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr11_+_63730720 0.694 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr18_+_70317548 0.688 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr14_-_105763152 0.645 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_64416307 0.626 SPTB
spectrin, beta, erythrocytic
chr1_-_200396354 0.608 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_27825633 0.604 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr14_-_106289751 0.547 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr1_-_1139358 0.526 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr3_-_58538110 0.520 FAM107A
family with sequence similarity 107, member A
chr14_-_105762742 0.513


chr14_-_105862080 0.507 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr15_-_38185578 0.461 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr1_-_155053124 0.446 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr13_+_96592051 0.444 MBNL2
muscleblind-like 2 (Drosophila)
chr1_-_144426918 0.437 NM_007053
CD160
CD160 molecule
chr16_-_727889 0.427 NARFL
nuclear prelamin A recognition factor-like
chr14_-_106202262 0.426 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr22_-_37480898 0.423 SUN2
Sad1 and UNC84 domain containing 2
chr6_-_6265896 0.409 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr6_+_31746706 0.391 NM_021221
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr18_-_46600295 0.388 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr5_-_176869943 0.386 NM_001144875
NM_001144876
DOK3

docking protein 3

chr4_-_41849333 0.382 BEND4
BEN domain containing 4
chr1_-_171441234 0.376 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr3_+_46423682 0.350 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr17_-_59818033 0.317 PECAM1
platelet/endothelial cell adhesion molecule
chr19_+_60109319 0.305 NM_001145457
NM_001145458
NM_004829
NCR1


natural cytotoxicity triggering receptor 1


chr6_-_6265874 0.289 F13A1
coagulation factor XIII, A1 polypeptide
chr14_-_105796665 0.265 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr1_-_155052562 0.249 NM_001161443
SH2D2A
SH2 domain containing 2A
chr14_-_105644300 0.244 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr4_+_71713324 0.240 NM_031889
ENAM
enamelin
chr4_+_154397975 0.223 TRIM2
tripartite motif containing 2
chr8_+_7139945 0.216 NM_001164453
FAM90A20
family with sequence similarity 90, member A20
chr9_-_116196505 0.212 NM_030767
AKNA
AT-hook transcription factor
chr5_-_149772469 0.196 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr5_+_95008236 0.180 NM_001131066
NM_001131065
NM_173362
RFESD


Rieske (Fe-S) domain containing


chr8_+_7663908 0.178 NM_001164447
FAM90A10
family with sequence similarity 90, member A10
chr17_-_37599953 0.178 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr1_+_22852268 0.178 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr1_+_233597350 0.172 NM_001079515
NM_003193
TBCE

tubulin folding cofactor E

chr11_+_60858611 0.171 DAK
dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr14_-_106270497 0.167 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr4_-_69852090 0.166 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr14_-_20563698 0.152 NDRG2
NDRG family member 2
chr3_-_58538530 0.148 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr5_+_140605330 0.140 NM_018935
PCDHB15
protocadherin beta 15
chr14_-_105817101 0.138


chr16_-_11783908 0.134 NM_014153
ZC3H7A
zinc finger CCCH-type containing 7A
chr19_+_4742727 0.127 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr2_-_104834344 0.125 LOC100506421
hypothetical LOC100506421
chr14_-_106184988 0.121 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_105623358 0.120 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr8_-_7427584 0.119 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr19_-_46626474 0.118 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr11_+_63060848 0.115 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr10_+_102748062 0.113 LZTS2
leucine zipper, putative tumor suppressor 2
chr8_+_7618022 0.111 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr17_+_35425139 0.109 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr6_+_38798529 0.103 NM_001371
DNAH8
dynein, axonemal, heavy chain 8
chr1_+_111963920 0.099 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr3_+_160269734 0.098 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr10_-_116434102 0.098 ABLIM1
actin binding LIM protein 1
chr1_+_43837096 0.096 PTPRF
protein tyrosine phosphatase, receptor type, F
chr22_-_37858871 0.091 CBX7
chromobox homolog 7
chr13_-_99983945 0.089 NM_033110
A2LD1
AIG2-like domain 1
chr4_+_1923629 0.088 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr8_+_7648613 0.088 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr7_+_142670624 0.084 NM_001143679
NM_001143680
NM_001143681
NM_015917
GSTK1



glutathione S-transferase kappa 1



chr14_-_106064887 0.080 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr15_+_71522551 0.080 NM_001042367
C15orf60
chromosome 15 open reading frame 60
chr19_+_55164668 0.079 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr8_+_7610374 0.075 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr14_-_20563722 0.070 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr8_+_7656261 0.070 NM_001164448
FAM90A9
family with sequence similarity 90, member A9
chr16_-_20246309 0.067 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr8_+_7132323 0.065 NM_001164455
FAM90A5
family with sequence similarity 90, member A5
chr1_+_233597385 0.064 TBCE
tubulin folding cofactor E
chr15_+_50098700 0.060 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr15_+_22772545 0.060 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr8_+_62363078 0.057 NM_173519
CLVS1
clavesin 1
chr19_-_59568483 0.054 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr16_-_66528235 0.053 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr4_-_164614335 0.053 NM_032136
TKTL2
transketolase-like 2
chr8_+_7633318 0.051 NM_001164450
FAM90A8
family with sequence similarity 90, member A8
chr1_+_12108542 0.049 NM_152942
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr8_-_7404643 0.048 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr9_-_106401514 0.046 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr9_+_94776538 0.045 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr7_-_150576957 0.043 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_113165134 0.042 LOC390251
SH3-domain GRB2-like 1 pseudogene
chr6_+_29187565 0.041 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr22_+_22363047 0.040 NM_153615
RGL4
ral guanine nucleotide dissociation stimulator-like 4
chr1_-_157950898 0.039 NM_000567
CRP
C-reactive protein, pentraxin-related
chr1_+_151655623 0.038 NM_176823
S100A7A
S100 calcium binding protein A7A
chr8_+_7124701 0.037 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr3_-_153541468 0.035 NM_001123228
TMEM14E
transmembrane protein 14E
chr19_+_42033564 0.034 ZNF345
zinc finger protein 345
chr2_+_241193492 0.033 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr11_+_111602287 0.033 NM_000317
PTS
6-pyruvoyltetrahydropterin synthase
chr9_+_126253243 0.028 NM_001161808
GPR144
G protein-coupled receptor 144
chr1_-_148249152 0.027 NM_020205
OTUD7B
OTU domain containing 7B
chr20_-_36191623 0.026 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr6_-_134415311 0.025 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr14_+_20226762 0.025 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr20_-_23617606 0.025 NM_001899
CST4
cystatin S
chr5_-_13997588 0.023 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr15_+_83092525 0.023 ZNF592
zinc finger protein 592
chr15_+_83092806 0.020 NM_014630
ZNF592
zinc finger protein 592
chr4_+_159812683 0.020 NM_004453
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr22_-_41353575 0.019 CYB5R3
cytochrome b5 reductase 3
chr6_-_31007905 0.019 NM_205854
SFTA2
surfactant associated 2
chr19_+_6981593 0.018 NM_001136507
MBD3L5
methyl-CpG-binding domain protein 3-like 5-like
chr7_-_94791670 0.018 PON1
paraoxonase 1
chr2_+_28572441 0.016 NM_001170585
NM_153021
PLB1

phospholipase B1

chr12_+_49604782 0.014 NM_014033
METTL7A
methyltransferase like 7A
chr2_-_169455167 0.014 NM_020675
SPC25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr21_+_30886629 0.010 NM_181605
KRTAP6-3
keratin associated protein 6-3
chr22_+_20929199 0.010 NM_007128
VPREB1
pre-B lymphocyte 1
chr12_-_102874980 0.010 NM_001135570
C12orf73
chromosome 12 open reading frame 73
chr1_+_179269766 0.009 MR1
major histocompatibility complex, class I-related
chr3_+_185515108 0.009 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr20_-_23679558 0.009 NM_001898
CST1
cystatin SN
chr17_+_7264366 0.008 NM_199339
SPEM1
spermatid maturation 1
chr15_+_63701322 0.007 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr8_+_7101835 0.007 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr17_-_45619038 0.003 COL1A1
collagen, type I, alpha 1
chr9_-_124370576 0.002 NM_001004454
OR1L8
olfactory receptor, family 1, subfamily L, member 8
chr9_-_132759045 0.000 NM_198180
QRFP
pyroglutamylated RFamide peptide
chrX_-_6463158 0.000 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.68 7.95e-04 GO:0006955 immune response
2.63 1.88e-02 GO:0002376 immune system process
35.18 3.77e-02 GO:0050710 negative regulation of cytokine secretion

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
28.15 3.63e-08 GO:0003823 antigen binding