Motif ID: CDC5L.p2

Z-value: 1.428


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)



Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_13992351 3.307 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr5_-_138238877 2.890 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr5_-_138238891 2.748 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr2_-_160764819 2.522 NM_000888
ITGB6
integrin, beta 6
chr13_-_85271329 2.413 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr5_-_138238953 2.040 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr2_-_162808123 1.864 NM_004460
FAP
fibroblast activation protein, alpha
chr2_-_160765008 1.731 ITGB6
integrin, beta 6
chr6_+_132000134 1.566 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr8_+_75899326 1.563 NM_015886
PI15
peptidase inhibitor 15
chr19_-_21438525 1.543


chr10_+_111755715 1.409 NM_019903
ADD3
adducin 3 (gamma)
chr14_+_38772870 1.361 NM_054024
MIA2
melanoma inhibitory activity 2
chr18_-_29882555 1.341 NM_001198549
NOL4
nucleolar protein 4
chr10_-_21226536 1.295 NM_006393
NEBL
nebulette
chr17_-_57023322 1.289 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr8_+_1940282 1.215 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr4_-_149577404 1.213


chr9_+_74956614 1.204 ANXA1
annexin A1
chr3_-_156876798 1.178 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr6_-_116973465 1.176 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr1_+_557269 1.175


chrX_-_15312390 1.154 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr12_+_16391795 1.135 NM_020300
NM_145791
MGST1

microsomal glutathione S-transferase 1

chr12_-_78831821 1.116 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr9_+_74956601 1.106 ANXA1
annexin A1
chr9_+_74956494 1.080 NM_000700
ANXA1
annexin A1
chr6_-_49712483 1.072 NM_000324
RHAG
Rh-associated glycoprotein
chr4_+_53986759 1.044 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr1_+_194887630 1.039 NM_000186
NM_001014975
CFH

complement factor H

chr19_-_10558906 1.036 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_-_180624380 1.001 GLUL
glutamate-ammonia ligase
chr6_-_112001590 0.996 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr4_-_68432293 0.968 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr7_-_16471817 0.952 NM_015464
SOSTDC1
sclerostin domain containing 1
chr9_+_129066576 0.948 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr16_+_14201687 0.928 MKL2
MKL/myocardin-like 2
chr1_+_10432362 0.924 NM_001302
CORT
cortistatin
chr1_-_75849350 0.915 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr15_+_100175888 0.909 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chr5_+_140751666 0.909 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr3_-_110155237 0.901 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr18_+_54039818 0.899 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr14_+_28311740 0.892 C14orf23
chromosome 14 open reading frame 23
chr4_+_47403107 0.881


chr1_+_25471470 0.845 NM_001127691
NM_016124
RHD

Rh blood group, D antigen

chr12_+_21417068 0.842 NM_000415
IAPP
islet amyloid polypeptide
chr4_-_15549047 0.838 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr6_-_119137923 0.838 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr2_+_165858586 0.821 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr12_+_18305740 0.804 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr10_-_69267774 0.795 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr20_+_43691797 0.787 NM_080753
WFDC10A
WAP four-disulfide core domain 10A
chr4_-_68678181 0.781 NM_207407
TMPRSS11F
transmembrane protease, serine 11F
chr1_+_556968 0.781


chr6_-_155818728 0.776 NM_015718
NOX3
NADPH oxidase 3
chr3_+_123526700 0.764 NM_005213
CSTA
cystatin A (stefin A)
chrX_+_65300803 0.759 NM_001130860
NM_014799
HEPH

hephaestin

chr4_-_140280031 0.753 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr9_+_134843918 0.745 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr2_-_180319013 0.736 NM_001113397
ZNF385B
zinc finger protein 385B
chr12_+_79127363 0.735 NM_173591
OTOGL
otogelin-like
chr12_-_10433852 0.724 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr4_+_130236731 0.723 NM_001099783
C4orf33
chromosome 4 open reading frame 33
chr2_+_100453375 0.720 NM_001011717
NMS
neuromedin S
chr4_+_88939725 0.706 NM_004967
IBSP
integrin-binding sialoprotein
chr5_+_156540425 0.696 NM_005546
ITK
IL2-inducible T-cell kinase
chr14_-_80934523 0.694 NM_033104
STON2
stonin 2
chr1_+_227506751 0.694 NM_006542
SPHAR
S-phase response (cyclin related)
chr4_-_80548378 0.693 NM_033214
GK2
glycerol kinase 2
chr3_-_95230143 0.689 NM_001001850
STX19
syntaxin 19
chr3_-_152517204 0.684 NM_023915
GPR87
G protein-coupled receptor 87
chr2_+_183316574 0.681 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chrX_-_15593074 0.681 NM_020665
TMEM27
transmembrane protein 27
chr11_+_27019084 0.680 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_66230977 0.679 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr7_-_111216180 0.677 DOCK4
dedicator of cytokinesis 4
chr1_-_25619863 0.670 NM_020485
NM_138616
NM_138617
NM_138618
RHCE



RHD
Rh blood group, CcEe antigens



Rh blood group, D antigen
chr10_-_105835609 0.664 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr4_-_40211324 0.662 RBM47
RNA binding motif protein 47
chr4_+_128773529 0.658 NM_015693
INTU
inturned planar cell polarity effector homolog (Drosophila)
chr15_+_30721161 0.657 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr21_+_38550533 0.653 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_-_19598912 0.652 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr9_+_109131814 0.652 RAD23B
RAD23 homolog B (S. cerevisiae)
chr1_+_151270301 0.635 NM_003125
SPRR1B
small proline-rich protein 1B
chr1_-_180624494 0.633 GLUL
glutamate-ammonia ligase
chr12_+_97513644 0.628 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr1_+_100099353 0.627 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr1_-_184696839 0.620 NM_002597
PDC
phosducin
chr15_-_39151468 0.610 INO80
INO80 homolog (S. cerevisiae)
chr2_-_162717159 0.604 NM_002054
GCG
glucagon
chr6_+_105511615 0.601 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chrX_-_106336199 0.597 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chrX_-_117003310 0.596 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr18_+_606671 0.592 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr6_-_50025115 0.587 NM_001166478
DEFB133
defensin, beta 133
chr11_-_5766621 0.586 NM_001001913
OR52N1
olfactory receptor, family 52, subfamily N, member 1
chr1_-_120112989 0.586 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr4_-_159313167 0.583 NM_016613
FAM198B
family with sequence similarity 198, member B
chr3_-_9266251 0.583 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr2_+_214984705 0.579 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr16_-_45562840 0.578 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr2_-_197383120 0.573 NM_213608
C2orf66
chromosome 2 open reading frame 66
chr1_-_229627412 0.571 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr9_+_101717278 0.570 STX17
syntaxin 17
chr4_+_106851415 0.565 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr12_+_77963563 0.565 NM_001135806
SYT1
synaptotagmin I
chr11_+_33306652 0.559 HIPK3
homeodomain interacting protein kinase 3
chr11_-_89293223 0.557 NM_001105522
TRIM49L1
tripartite motif containing 49-like 1
chr3_+_142175329 0.556 SLC25A36
solute carrier family 25, member 36
chr16_+_24696069 0.540 TNRC6A
trinucleotide repeat containing 6A
chr3_+_191588354 0.539 NM_006580
CLDN16
claudin 16
chr11_-_1586190 0.533 NM_001012708
KRTAP5-3
keratin associated protein 5-3
chr12_-_38300109 0.532 NM_005164
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr1_-_202402043 0.531 NM_000537
REN
renin
chr4_+_109763119 0.530 RPL34
ribosomal protein L34
chr1_+_43063817 0.526 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr6_+_27400518 0.525 NM_032030
FKSG83
FKSG83
chr5_+_147423727 0.524 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr21_-_30796278 0.523 NM_181611
KRTAP19-5
keratin associated protein 19-5
chr2_-_61566477 0.522 XPO1
exportin 1 (CRM1 homolog, yeast)
chr18_-_53438854 0.518


chr1_-_20682541 0.516


chr1_+_156716290 0.513 NM_001004472
OR10R2
olfactory receptor, family 10, subfamily R, member 2
chr6_-_71069347 0.504 NM_001851
COL9A1
collagen, type IX, alpha 1
chr5_-_132228375 0.501 NM_005260
GDF9
growth differentiation factor 9
chr5_+_145297490 0.497 SH3RF2
SH3 domain containing ring finger 2
chr7_+_156716694 0.493


chr15_-_41195994 0.493 RPS3A
ribosomal protein S3A
chr4_+_74825138 0.484 NM_000584
IL8
interleukin 8
chr11_+_55617328 0.484 NM_001003750
OR8I2
olfactory receptor, family 8, subfamily I, member 2
chr8_+_7340777 0.483 NM_001037668
NM_001040705
DEFB107A
DEFB107B
defensin, beta 107A
defensin, beta 107B
chr2_-_178495768 0.475 NM_001077358
PDE11A
phosphodiesterase 11A
chr21_-_35174742 0.475 RUNX1
runt-related transcription factor 1
chr7_+_110518297 0.473 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr2_+_151922350 0.468 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr16_+_68238460 0.465 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr10_+_5126589 0.464 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_+_89602023 0.458 NM_198460
GBP6
guanylate binding protein family, member 6
chr22_-_34566367 0.457 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chrX_-_23955223 0.454 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr4_-_90197140 0.453 NM_014883
FAM13A
family with sequence similarity 13, member A
chr1_+_184532027 0.453 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr10_+_5126556 0.450 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_+_149897334 0.445 SNX27
sorting nexin family member 27
chr1_+_114295289 0.442 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr6_+_147568795 0.441 STXBP5
syntaxin binding protein 5 (tomosyn)
chr3_-_121117647 0.441 GSK3B
glycogen synthase kinase 3 beta
chr12_-_52975823 0.439 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr2_+_227900471 0.435 NM_020194
MFF
mitochondrial fission factor
chr4_-_95482994 0.434 NM_014485
HPGDS
hematopoietic prostaglandin D synthase
chr4_-_83566246 0.434 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr14_-_22947320 0.428 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr1_-_20374273 0.426 NM_001105572
PLA2G2C
phospholipase A2, group IIC
chr11_-_100505667 0.424 NM_000926
PGR
progesterone receptor
chr9_+_104797413 0.424 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr2_+_166034402 0.423 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chrX_-_127014020 0.422 NM_138289
ACTRT1
actin-related protein T1
chr2_+_73973640 0.421 ACTG2
actin, gamma 2, smooth muscle, enteric
chr6_+_125346208 0.421 NM_152553
RNF217
ring finger protein 217
chr1_-_159543847 0.417 MPZ
myelin protein zero
chr5_-_125956996 0.416 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr2_+_89849009 0.415


chr4_+_155707089 0.415 FGB
fibrinogen beta chain
chr4_+_95595419 0.414 PDLIM5
PDZ and LIM domain 5
chr1_+_195503956 0.411 NM_001193640
NM_201253
CRB1

crumbs homolog 1 (Drosophila)

chr3_+_103636548 0.410 NM_175056
ZPLD1
zona pellucida-like domain containing 1
chr6_-_76027286 0.409 TMEM30A
transmembrane protein 30A
chr11_-_106833715 0.409 NM_152434
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr11_+_111552298 0.405 NM_001037290
BCO2
beta-carotene oxygenase 2
chr7_+_77307382 0.404 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr4_-_145159889 0.404 NM_002100
GYPB
glycophorin B (MNS blood group)
chr11_+_59580705 0.403 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr6_-_38671741 0.403 NM_001172418
NM_152733
BTBD9

BTB (POZ) domain containing 9

chr10_+_5126613 0.403 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr8_+_133060353 0.402 EFR3A
EFR3 homolog A (S. cerevisiae)
chr12_+_53534565 0.401 NM_058173
MUCL1
mucin-like 1
chr11_+_111551417 0.397 NM_031938
BCO2
beta-carotene oxygenase 2
chrX_+_125781427 0.395 NM_001122716
CXorf64
chromosome X open reading frame 64
chr2_+_79106333 0.395 NM_001008387
NM_198448
REG3G

regenerating islet-derived 3 gamma

chr11_+_86710076 0.393 TMEM135
transmembrane protein 135
chr3_+_63859114 0.392 NM_001177387
ATXN7
ataxin 7
chr17_-_36451189 0.388 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr12_+_56802 0.388 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr13_-_40491405 0.386 ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_-_171796069 0.386 NM_001136554
TLK1
tousled-like kinase 1
chr1_-_218329684 0.385 BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr4_-_74307637 0.385 ANKRD17
ankyrin repeat domain 17
chr10_+_49279647 0.384 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr11_-_16454493 0.383 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr13_-_40491491 0.383 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_+_129057152 0.379 NM_001040110
NRF1
nuclear respiratory factor 1
chr10_+_35524060 0.377 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr2_+_165804157 0.376 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr1_-_93030538 0.376 NM_005665
EVI5
ecotropic viral integration site 5
chr2_-_21106291 0.371 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_-_61098867 0.370 NM_144709
PUS10
pseudouridylate synthase 10
chr1_+_184636326 0.369 NM_022375
OCLM
oculomedin
chrX_-_110541029 0.369 NM_000555
DCX
doublecortin

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.46 1.90e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.05 3.27e-02 GO:0004984 olfactory receptor activity
3.42 4.18e-02 GO:0004867 serine-type endopeptidase inhibitor activity