Motif ID: CDX1,2,4.p2

Z-value: 1.199


Transcription factors associated with CDX1,2,4.p2:

Gene SymbolEntrez IDGene Name
CDX1 1044 caudal type homeobox 1
CDX2 1045 caudal type homeobox 2
CDX4 1046 caudal type homeobox 4



Activity profile for motif CDX1,2,4.p2.

activity profile for motif CDX1,2,4.p2


Sorted Z-values histogram for motif CDX1,2,4.p2

Sorted Z-values for motif CDX1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_98757634 2.218 NM_004951
GPR183
G protein-coupled receptor 183
chr2_+_161701711 1.902 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr1_+_158975662 1.772 NM_021181
SLAMF7
SLAM family member 7
chr12_+_53178834 1.647 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr7_-_112513379 1.610 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr4_-_38460983 1.537 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
TLR10




toll-like receptor 10




chr10_-_98021144 1.416 NM_001114094
NM_013314
BLNK

B-cell linker

chr1_+_190811479 1.387 NM_002922
RGS1
regulator of G-protein signaling 1
chr2_-_45648608 1.354 SRBD1
S1 RNA binding domain 1
chr17_-_5078773 1.347 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr12_+_9713472 1.163 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr16_+_27346079 1.159 NM_021798
IL21R
interleukin 21 receptor
chr14_-_30927931 1.154 NM_015473
HEATR5A
HEAT repeat containing 5A
chr20_-_33783409 1.031 RBM39
RNA binding motif protein 39
chr22_+_36008511 1.003 CYTH4
cytohesin 4
chr10_+_89257569 0.984 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr1_+_239762179 0.975 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr8_-_110411283 0.970 NM_001128211
NUDCD1
NudC domain containing 1
chr6_+_64344307 0.936 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_-_184756101 0.907 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr2_+_38009405 0.889 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr5_-_98290117 0.889 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr5_+_141326620 0.888 NM_183399
RNF14
ring finger protein 14
chr19_+_40895669 0.869 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr22_+_36008465 0.865 CYTH4
cytohesin 4
chr19_-_44518516 0.852 NM_004877
GMFG
glia maturation factor, gamma
chr8_-_66863841 0.850 NM_002603
PDE7A
phosphodiesterase 7A
chrX_+_100241453 0.843 NM_006733
CENPI
centromere protein I
chr17_-_35975227 0.828 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_-_155788775 0.824 NM_001195388
NM_031281
FCRL5

Fc receptor-like 5

chr19_+_14554895 0.819 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr7_+_73826244 0.808 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr1_+_165565006 0.807 POU2F1
POU class 2 homeobox 1
chr1_-_155834357 0.794 NM_031282
FCRL4
Fc receptor-like 4
chr1_-_100003936 0.789 NM_001013660
FRRS1
ferric-chelate reductase 1
chr5_+_68703036 0.770 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr5_+_40877053 0.746 NM_032587
CARD6
caspase recruitment domain family, member 6
chr20_-_33658823 0.717 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr18_-_53438854 0.711


chr13_-_40491405 0.711 ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_-_112545840 0.702 LOC401397
hypothetical LOC401397
chr19_-_55539769 0.700 NAPSB
napsin B aspartic peptidase pseudogene
chr7_-_112545847 0.700 LOC401397
hypothetical LOC401397
chr7_-_13992351 0.697 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr19_+_53450743 0.696


chr15_-_78050515 0.682 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr22_+_36008369 0.680 NM_013385
CYTH4
cytohesin 4
chr11_-_16953135 0.678 RPL36A
ribosomal protein L36a
chr12_+_102859354 0.677 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_-_11075272 0.674 NM_176885
TAS2R31
taste receptor, type 2, member 31
chr13_-_40491491 0.674 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr12_+_9925354 0.673 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr6_-_49942147 0.668 NM_001131
NM_170609
CRISP1

cysteine-rich secretory protein 1

chr1_-_165326148 0.662 NM_005814
GPA33
glycoprotein A33 (transmembrane)
chr11_-_17147863 0.659 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr14_+_87541220 0.658 NM_003608
GPR65
G protein-coupled receptor 65
chr8_-_7207899 0.657 NM_001164457
ZNF705G
zinc finger protein 705G
chr2_+_227900471 0.653 NM_020194
MFF
mitochondrial fission factor
chr6_-_161333363 0.643


chr19_-_11550765 0.642 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr21_-_14840506 0.642 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr9_+_78305368 0.640 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr1_-_24112345 0.632 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr1_-_178100204 0.612


chr6_+_126143971 0.607 NCOA7
nuclear receptor coactivator 7
chr2_-_21106291 0.604 APOB
apolipoprotein B (including Ag(x) antigen)
chr8_-_27997306 0.601 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr15_-_64582049 0.599 RPL4
ribosomal protein L4
chr12_+_91620749 0.599 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr4_-_47678187 0.596 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr12_-_51887318 0.594 ITGB7
integrin, beta 7
chr5_-_88155360 0.592 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr11_+_57285809 0.592 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001331
CTNND1












catenin (cadherin-associated protein), delta 1












chr10_+_91488704 0.586 KIF20B
kinesin family member 20B
chr16_+_20682812 0.583 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr12_-_51887266 0.581 NM_000889
ITGB7
integrin, beta 7
chr9_+_263025 0.579 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chrX_+_134803450 0.576 NM_018666
SAGE1
sarcoma antigen 1
chr12_-_8656705 0.573 NM_020661
AICDA
activation-induced cytidine deaminase
chr4_-_38710376 0.570 NM_024943
TMEM156
transmembrane protein 156
chr8_-_42742729 0.568 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr12_+_45896318 0.559 NM_138371
FAM113B
family with sequence similarity 113, member B
chr4_-_77163609 0.544 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr2_+_68815416 0.537 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr19_+_17253453 0.536 NM_152363
ANKLE1
ankyrin repeat and LEM domain containing 1
chr11_-_129268113 0.534 NM_006165
NFRKB
nuclear factor related to kappaB binding protein
chr12_+_130004404 0.532 NM_198827
GPR133
G protein-coupled receptor 133
chr19_-_6621078 0.531 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr6_-_137536412 0.530 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr2_-_242205556 0.527 NM_001164356
THAP4
THAP domain containing 4
chr4_+_159351092 0.526 TMEM144
transmembrane protein 144
chr3_-_113701073 0.518 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr10_+_97505398 0.514 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr10_+_5976354 0.514 NM_032807
FBXO18
F-box protein, helicase, 18
chr10_-_11614279 0.507 NM_001080491
USP6NL
USP6 N-terminal like
chr3_-_102522093 0.506 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr1_-_27825178 0.505 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr13_+_49487390 0.505 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr14_-_80475636 0.502 NM_152446
C14orf145
chromosome 14 open reading frame 145
chr22_-_15682555 0.494 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr3_-_17757402 0.493 NM_014744
TBC1D5
TBC1 domain family, member 5
chr13_+_96672705 0.490 MBNL2
muscleblind-like 2 (Drosophila)
chr12_-_12740387 0.488 NM_006143
GPR19
G protein-coupled receptor 19
chr5_+_159368733 0.486 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr1_+_84539876 0.485 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr10_+_51246290 0.480 NM_001145262
NCOA4
nuclear receptor coactivator 4
chrX_-_154216929 0.480 NM_001289
CLIC2
chloride intracellular channel 2
chr14_-_94677807 0.479 NM_030621
DICER1
dicer 1, ribonuclease type III
chr5_+_140690387 0.477 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr1_+_78243181 0.476 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_+_146097700 0.467 LOC100507557
hypothetical LOC100507557
chr1_-_181889070 0.466 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr1_-_1701313 0.465 NM_001198994
NADK
NAD kinase
chr6_-_42293577 0.465 MRPS10
mitochondrial ribosomal protein S10
chr2_-_179623030 0.462 NM_173648
CCDC141
coiled-coil domain containing 141
chr5_-_94442941 0.460 MCTP1
multiple C2 domains, transmembrane 1
chr10_-_85921703 0.457 LOC642934
hypothetical LOC642934
chr1_+_50348052 0.456 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_+_68702617 0.454 NM_133340
NM_133341
RAD17

RAD17 homolog (S. pombe)

chr12_-_78831821 0.452 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr6_+_53043729 0.452 NM_012347
FBXO9
F-box protein 9
chr4_-_17415918 0.451 DCAF16
DDB1 and CUL4 associated factor 16
chr17_+_36599664 0.448 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr5_-_149772563 0.447 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr5_-_149772469 0.446 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr17_+_7180571 0.445 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr3_-_143230124 0.442 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr16_+_11346780 0.435 NM_152308
C16orf75
chromosome 16 open reading frame 75
chr1_+_196874759 0.434 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr19_-_56612653 0.434 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr5_-_149772528 0.433


chr12_+_63510481 0.433


chr13_-_98708549 0.433 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr7_-_107930170 0.432 PNPLA8
patatin-like phospholipase domain containing 8
chr1_+_169549996 0.430 NM_002022
FMO4
flavin containing monooxygenase 4
chr12_+_74160779 0.430 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr3_-_122862391 0.426 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr22_+_22435207 0.424 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr18_-_46605730 0.421 NM_001127174
MRO
maestro
chr1_-_21288259 0.421 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr22_-_16080265 0.418 CECR1
cat eye syndrome chromosome region, candidate 1
chr14_+_75058591 0.418 BATF
basic leucine zipper transcription factor, ATF-like
chr1_+_178232379 0.417 CEP350
centrosomal protein 350kDa
chr5_+_76470829 0.415


chr15_+_62467055 0.413 NM_016213
TRIP4
thyroid hormone receptor interactor 4
chr1_-_143232526 0.412 FAM91A2
family with sequence similarity 91, member A2
chr6_+_158990982 0.410 NM_001009991
SYTL3
synaptotagmin-like 3
chr3_-_150569574 0.406 TM4SF1
transmembrane 4 L six family member 1
chr1_+_196874839 0.405 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_201755865 0.405 NM_001230
NM_032974
NM_032977
CASP10


caspase 10, apoptosis-related cysteine peptidase


chr18_-_26935883 0.403 NM_004949
NM_024422
DSC2

desmocollin 2

chr5_-_64813459 0.403 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr10_+_114125003 0.403 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr15_-_51839129 0.403 NM_182758
WDR72
WD repeat domain 72
chr10_+_70517863 0.402 SRGN
serglycin
chr11_-_59707074 0.402 NM_022349
NM_152851
NM_152852
MS4A6A


membrane-spanning 4-domains, subfamily A, member 6A


chr22_-_36212160 0.400 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr10_+_70517823 0.398 NM_002727
SRGN
serglycin
chr12_+_32723539 0.397 DNM1L
dynamin 1-like
chr10_+_35496449 0.396 NM_182771
NM_182772
CREM

cAMP responsive element modulator

chr6_-_133120587 0.392 NM_004665
VNN2
vanin 2
chr5_+_159368721 0.392 TTC1
tetratricopeptide repeat domain 1
chr17_-_31441390 0.388 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr11_+_63060848 0.388 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr2_-_97646970 0.388 NM_005735
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr2_-_224974954 0.386 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr15_-_38185865 0.386 NM_033503
BMF
Bcl2 modifying factor
chr12_-_9777126 0.386 NM_172004
CLECL1
C-type lectin-like 1
chr13_+_48582389 0.384 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr5_+_96237923 0.383 ERAP2
endoplasmic reticulum aminopeptidase 2
chr3_-_122862447 0.381 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr2_-_44440358 0.380 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr20_+_43423990 0.380 NM_001197129
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr7_+_101810018 0.379


chr10_+_70745615 0.376 NM_033496
HK1
hexokinase 1
chr16_+_20328355 0.373 NM_017888
ACSM5
acyl-CoA synthetase medium-chain family member 5
chr12_+_45896511 0.373 FAM113B
family with sequence similarity 113, member B
chr13_+_45174446 0.372 NM_152719
SPERT
spermatid associated
chr1_-_77457664 0.372 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr20_+_62158882 0.366 NM_198723
TCEA2
transcription elongation factor A (SII), 2
chr1_+_148511806 0.366 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr19_-_50838824 0.365 NM_001193269
EML2
echinoderm microtubule associated protein like 2
chr5_+_156628929 0.364 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_+_95595419 0.363 PDLIM5
PDZ and LIM domain 5
chr1_+_242283129 0.363 NM_006352
ZNF238
zinc finger protein 238
chrX_-_78509662 0.359 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr15_-_48192804 0.359 ATP8B4
ATPase, class I, type 8B, member 4
chr22_-_40666168 0.356 NM_001110215
CENPM
centromere protein M
chr11_-_104411065 0.355 NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CASP1




caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr8_+_86287161 0.355 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr10_-_50012058 0.354 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr21_-_42608531 0.352 TFF3
trefoil factor 3 (intestinal)
chr9_-_99740243 0.352 NM_197978
HEMGN
hemogen
chr3_-_42818221 0.349


chr3_-_152585226 0.349 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr4_-_84254932 0.348 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr5_+_159368690 0.348 TTC1
tetratricopeptide repeat domain 1
chr6_-_33085329 0.348 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr18_+_53865455 0.348 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_-_84254873 0.347 PLAC8
placenta-specific 8

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 6.48e-03 GO:0002376 immune system process
1.53 9.28e-03 GO:0006955 immune response
1.48 2.38e-02 GO:0006952 defense response

Nothing significant found in compartment category.

Nothing significant found in function category.