Motif ID: E2F1..5.p2

Z-value: 1.118


Transcription factors associated with E2F1..5.p2:

Gene SymbolEntrez IDGene Name
E2F1 1869 E2F transcription factor 1
E2F2 1870 E2F transcription factor 2
E2F3 1871 E2F transcription factor 3
E2F4 1874 E2F transcription factor 4, p107/p130-binding
E2F5 1875 E2F transcription factor 5, p130-binding



Activity profile for motif E2F1..5.p2.

activity profile for motif E2F1..5.p2


Sorted Z-values histogram for motif E2F1..5.p2

Sorted Z-values for motif E2F1..5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of E2F1..5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_18485145 2.551 RANBP1
RAN binding protein 1
chr11_-_33847507 2.413 LMO2
LIM domain only 2 (rhombotin-like 1)
chr22_+_18485068 2.355 RANBP1
RAN binding protein 1
chr22_+_18485057 2.290 RANBP1
RAN binding protein 1
chr5_-_146869613 2.211 DPYSL3
dihydropyrimidinase-like 3
chr22_+_18485076 2.181 RANBP1
RAN binding protein 1
chr17_-_43977273 2.163 NM_002145
HOXB2
homeobox B2
chr1_+_115198977 1.940 NM_003176
SYCP1
synaptonemal complex protein 1
chrX_+_101792949 1.908 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr22_+_18485095 1.825 RANBP1
RAN binding protein 1
chr14_+_85069217 1.802


chr1_-_26105230 1.730 NM_203401
STMN1
stathmin 1
chr5_-_146869811 1.690 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chrX_-_99873152 1.564 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr1_-_226712140 1.562 NM_033445
HIST3H2A
histone cluster 3, H2a
chr13_-_25523164 1.449 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr1_+_226712430 1.444 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr11_-_33848013 1.437 LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_33847834 1.437 LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_63195371 1.413 ATL3
atlastin GTPase 3
chr4_+_134292630 1.412 PCDH10
protocadherin 10
chr10_-_25281510 1.396 NM_020200
PRTFDC1
phosphoribosyl transferase domain containing 1
chr4_+_30331543 1.381 PCDH7
protocadherin 7
chr1_-_203985701 1.370 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr9_-_25668230 1.347 TUSC1
tumor suppressor candidate 1
chr11_-_33847937 1.329 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_19219000 1.322 NM_024680
E2F8
E2F transcription factor 8
chr8_-_124477639 1.298 ATAD2
ATPase family, AAA domain containing 2
chrX_-_53465847 1.290 SMC1A
structural maintenance of chromosomes 1A
chr4_+_30331289 1.283 PCDH7
protocadherin 7
chr10_+_8136639 1.278 NM_001002295
NM_002051
GATA3

GATA binding protein 3

chr2_+_188865634 1.266 NM_016315
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_149309703 1.260 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr4_+_30330963 1.256 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr15_-_81743198 1.251 BNC1
basonuclin 1
chr6_+_88356503 1.208 NM_001197259
NM_012381
NM_181837
ORC3


origin recognition complex, subunit 3


chr1_-_203985752 1.203 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_-_79986063 1.177 DHFR
dihydrofolate reductase
chr2_+_188865796 1.172 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr8_-_121526568 1.161 MRPL13
mitochondrial ribosomal protein L13
chr1_-_203985780 1.160 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_+_79986049 1.158 NM_002439
MSH3
mutS homolog 3 (E. coli)
chr15_+_45263517 1.149 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chrX_-_53466273 1.148 SMC1A
structural maintenance of chromosomes 1A
chr17_+_27288374 1.141


chr5_-_79986104 1.141 DHFR
dihydrofolate reductase
chr4_+_134289893 1.128 NM_020815
NM_032961
PCDH10

protocadherin 10

chr5_+_79986227 1.114 MSH3
mutS homolog 3 (E. coli)
chr5_+_79986222 1.113 MSH3
mutS homolog 3 (E. coli)
chr10_+_17311307 1.094 VIM
vimentin
chr10_+_17311347 1.093 VIM
vimentin
chr11_-_62379788 1.089 SNHG1
small nucleolar RNA host gene 1 (non-protein coding)
chr6_+_72949092 1.081 RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_170221584 1.070 NM_022897
RANBP17
RAN binding protein 17
chr15_+_42507123 1.063 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chrX_-_53466335 1.063 NM_006306
SMC1A
structural maintenance of chromosomes 1A
chr8_-_121526514 1.061 MRPL13
mitochondrial ribosomal protein L13
chr8_-_98359248 1.054 TSPYL5
TSPY-like 5
chr6_-_88356445 1.050 NM_020320
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr1_-_91260131 1.046 ZNF644
zinc finger protein 644
chr10_+_99463468 1.037 MARVELD1
MARVEL domain containing 1
chr1_-_24179326 1.031 SRSF10
serine/arginine-rich splicing factor 10
chr10_+_99463446 1.003 NM_031484
MARVELD1
MARVEL domain containing 1
chr19_-_57082907 0.997 NM_001135590
NM_032679
ZNF577

zinc finger protein 577

chr7_-_94123308 0.993 SGCE
sarcoglycan, epsilon
chr5_+_79986254 0.984 MSH3
mutS homolog 3 (E. coli)
chr6_-_88356411 0.982 RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr11_+_62380042 0.982 NM_001012662
NM_001012664
NM_002394
NM_001012661
NM_001012663
SLC3A2




solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2




chr10_+_17311283 0.978 VIM
vimentin
chr7_-_44854092 0.967 H2AFV
H2A histone family, member V
chr10_+_17311282 0.958 VIM
vimentin
chr11_-_117252541 0.950 FXYD6
FXYD domain containing ion transport regulator 6
chr3_+_14195231 0.944 NM_014463
LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_-_99873728 0.941 NM_001129896
SYTL4
synaptotagmin-like 4
chr7_-_94123362 0.939 SGCE
sarcoglycan, epsilon
chr6_-_27222556 0.934 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr7_-_44854222 0.934 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr8_+_121526823 0.933 NM_022045
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr11_+_12987455 0.932 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr16_+_28798735 0.927 ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr8_-_124477846 0.916 ATAD2
ATPase family, AAA domain containing 2
chr1_-_203985932 0.914


chr8_-_98359347 0.911 NM_033512
TSPYL5
TSPY-like 5
chr1_+_231816540 0.911 KCNK1
potassium channel, subfamily K, member 1
chr8_+_55533047 0.909 NM_022454
SOX17
SRY (sex determining region Y)-box 17
chr22_+_18484810 0.900 NM_002882
RANBP1
RAN binding protein 1
chr3_+_14195333 0.899 LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_33275051 0.898 AK2
adenylate kinase 2
chr17_+_27288253 0.897 SUZ12
suppressor of zeste 12 homolog (Drosophila)
chr8_-_98359366 0.890 TSPYL5
TSPY-like 5
chr10_+_8136778 0.874 GATA3
GATA binding protein 3
chr11_-_118739838 0.872 USP2
ubiquitin specific peptidase 2
chr11_-_77383307 0.870 INTS4
integrator complex subunit 4
chr1_-_29380850 0.869 SRSF4
serine/arginine-rich splicing factor 4
chr1_-_33275057 0.868 NM_001625
AK2
adenylate kinase 2
chr1_-_91260181 0.868 NM_032186
NM_201269
ZNF644

zinc finger protein 644

chr7_-_44854183 0.866 H2AFV
H2A histone family, member V
chr7_+_26207854 0.866 CBX3
chromobox homolog 3
chr1_-_33275039 0.864 AK2
adenylate kinase 2
chr11_-_77383359 0.864 NM_033547
INTS4
integrator complex subunit 4
chr8_-_121526806 0.856 NM_014078
MRPL13
mitochondrial ribosomal protein L13
chr7_-_44854145 0.853 H2AFV
H2A histone family, member V
chr1_-_33275071 0.853 NM_013411
AK2
adenylate kinase 2
chr1_+_231816372 0.849 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chrX_+_133421963 0.846 HPRT1
hypoxanthine phosphoribosyltransferase 1
chr2_+_71534260 0.846 NM_001130976
NM_001130977
NM_001130978
NM_001130979
NM_001130980
NM_001130981
NM_003494
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr3_-_14195075 0.844 NM_001145769
NM_004628
XPC

xeroderma pigmentosum, complementation group C

chr1_-_91260174 0.843 ZNF644
zinc finger protein 644
chr9_-_23811808 0.840 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_94123413 0.839 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr1_-_203985896 0.836 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr10_+_17311242 0.832 VIM
vimentin
chr12_+_97511805 0.827 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr15_+_42507057 0.822 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_-_203985963 0.816 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr7_+_120378052 0.812 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr6_-_144370947 0.809 PLAGL1
pleiomorphic adenoma gene-like 1
chr9_+_115678365 0.807 NM_133374
ZNF618
zinc finger protein 618
chr8_-_95634845 0.807 NM_015496
NM_183009
KIAA1429

KIAA1429

chr13_-_109236897 0.805 NM_003749
IRS2
insulin receptor substrate 2
chr7_-_99537362 0.804 NM_005916
MCM7
minichromosome maintenance complex component 7
chr6_+_135544138 0.803 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr1_+_85819004 0.800 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr1_-_68470585 0.795 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr7_-_44854188 0.795 H2AFV
H2A histone family, member V
chr2_+_27293846 0.795 CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr8_-_124477869 0.792 NM_014109
ATAD2
ATPase family, AAA domain containing 2
chrX_+_133421891 0.787 HPRT1
hypoxanthine phosphoribosyltransferase 1
chr3_-_52694554 0.786 NM_018313
PBRM1
polybromo 1
chr19_-_58449752 0.785 ZNF677
zinc finger protein 677
chr1_-_91259601 0.784 NM_016620
ZNF644
zinc finger protein 644
chr3_+_14195347 0.783 LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_+_26207897 0.782 CBX3
chromobox homolog 3
chr13_+_44592647 0.775 GTF2F2
general transcription factor IIF, polypeptide 2, 30kDa
chr13_+_33290254 0.775 RFC3
replication factor C (activator 1) 3, 38kDa
chr9_-_121171400 0.768 NM_014618
DBC1
deleted in bladder cancer 1
chr4_+_152240182 0.762 NM_001006
RPS3A
ribosomal protein S3A
chr9_+_35782405 0.757 NM_003995
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr6_-_27208507 0.757 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr2_-_136350404 0.755 MCM6
minichromosome maintenance complex component 6
chr1_-_210275402 0.751 NM_015434
INTS7
integrator complex subunit 7
chr22_+_49293520 0.745 NCAPH2
non-SMC condensin II complex, subunit H2
chr7_+_138695241 0.742 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr6_+_135544170 0.742 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr15_+_28705656 0.737 ARHGAP11B
Rho GTPase activating protein 11B
chr12_-_109665019 0.737 PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
chr3_+_144321286 0.735 NM_004267
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr13_+_47775951 0.734 RB1
retinoblastoma 1
chr6_+_27222839 0.733 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr7_+_1239078 0.733 NM_001080461
UNCX
UNC homeobox
chr5_+_170221441 0.727 RANBP17
RAN binding protein 17
chr11_-_64302509 0.727 NM_001178030
SF1
splicing factor 1
chr9_-_23811842 0.726 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_-_64302440 0.724 SF1
splicing factor 1
chr6_+_27208763 0.721 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr10_+_62208256 0.721 CDK1
cyclin-dependent kinase 1
chr6_+_135544214 0.719 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr8_-_124477850 0.716 ATAD2
ATPase family, AAA domain containing 2
chr16_-_3870121 0.715 NM_001079846
NM_004380
CREBBP

CREB binding protein

chr21_+_29592984 0.704 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_+_108666725 0.702 NXT2
nuclear transport factor 2-like export factor 2
chr8_+_49036086 0.702 MCM4
minichromosome maintenance complex component 4
chrX_-_62891667 0.700 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_+_27293737 0.697 NM_004341
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chrX_+_108666891 0.693 NXT2
nuclear transport factor 2-like export factor 2
chr7_+_138695144 0.684 NM_016019
LUC7L2
LUC7-like 2 (S. cerevisiae)
chrX_+_118592568 0.682 UBE2A
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr2_-_144991556 0.677 ZEB2
zinc finger E-box binding homeobox 2
chr7_+_138695236 0.675 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr1_+_210275752 0.673 DTL
denticleless homolog (Drosophila)
chr11_-_64302564 0.671 SF1
splicing factor 1
chr13_+_47776026 0.669 RB1
retinoblastoma 1
chr22_-_18484695 0.668 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr7_+_138695209 0.668 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr7_-_106088565 0.667 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr11_-_77528267 0.666 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr9_+_134884627 0.666 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_+_219141761 0.663 NM_005444
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr1_+_61315516 0.662 NM_001145511
NFIA
nuclear factor I/A
chr11_-_77528308 0.662 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr3_-_162305319 0.660 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr1_+_52642802 0.660 NM_032864
PRPF38A
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chr21_+_29593088 0.659 NM_001186
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_-_27949266 0.657 NM_003546
HIST1H4L
histone cluster 1, H4l
chr9_-_97119677 0.654 NM_000136
FANCC
Fanconi anemia, complementation group C
chr19_-_58449919 0.654 NM_182609
ZNF677
zinc finger protein 677
chr19_+_41397819 0.654 ZNF146
zinc finger protein 146
chrX_+_122923279 0.653 STAG2
stromal antigen 2
chr7_+_88226617 0.651 NM_181646
ZNF804B
zinc finger protein 804B
chr3_+_37010270 0.651 NM_001167617
NM_001167618
NM_001167619
MLH1


mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)


chrX_+_122923236 0.650 NM_001042750
NM_001042751
NM_006603
STAG2


stromal antigen 2


chr19_+_54280528 0.650 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr19_-_55124459 0.647 IL4I1
interleukin 4 induced 1
chrX_-_135941498 0.644 NM_054021
GPR101
G protein-coupled receptor 101
chr1_+_52642826 0.644 PRPF38A
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chr12_-_75983329 0.643 NM_203394
E2F7
E2F transcription factor 7
chr3_+_5139032 0.639 ARL8B
ADP-ribosylation factor-like 8B
chr4_+_134293171 0.639 PCDH10
protocadherin 10
chr12_-_109664882 0.638 PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
chr1_+_61315378 0.638



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.92 6.38e-26 GO:0090304 nucleic acid metabolic process
1.79 1.04e-25 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 1.49e-22 GO:0044260 cellular macromolecule metabolic process
2.28 3.28e-20 GO:0007049 cell cycle
1.61 1.47e-18 GO:0034641 cellular nitrogen compound metabolic process
1.59 9.77e-18 GO:0006807 nitrogen compound metabolic process
1.43 5.15e-17 GO:0043170 macromolecule metabolic process
2.32 4.13e-16 GO:0022402 cell cycle process
1.84 5.95e-16 GO:0016070 RNA metabolic process
2.40 4.76e-15 GO:0022403 cell cycle phase
1.33 7.66e-14 GO:0044237 cellular metabolic process
1.74 2.45e-13 GO:0010467 gene expression
1.31 4.75e-13 GO:0044238 primary metabolic process
2.44 7.79e-12 GO:0016071 mRNA metabolic process
1.16 4.98e-11 GO:0009987 cellular process
1.45 9.14e-11 GO:0071840 cellular component organization or biogenesis
1.45 1.16e-10 GO:0016043 cellular component organization
2.29 1.52e-10 GO:0000278 mitotic cell cycle
2.23 3.10e-10 GO:0051276 chromosome organization
1.51 3.94e-10 GO:0071841 cellular component organization or biogenesis at cellular level
4.06 1.63e-09 GO:0071824 protein-DNA complex subunit organization
4.16 1.64e-09 GO:0065004 protein-DNA complex assembly
1.24 3.12e-09 GO:0008152 metabolic process
1.50 4.35e-09 GO:0071842 cellular component organization at cellular level
2.19 5.95e-09 GO:0006259 DNA metabolic process
2.39 9.96e-09 GO:0000279 M phase
3.44 2.10e-08 GO:0071103 DNA conformation change
4.13 2.27e-08 GO:0031497 chromatin assembly
2.27 2.71e-08 GO:0034621 cellular macromolecular complex subunit organization
2.09 3.44e-08 GO:0006396 RNA processing
1.62 7.69e-08 GO:0034645 cellular macromolecule biosynthetic process
3.59 7.81e-08 GO:0006323 DNA packaging
1.90 1.48e-07 GO:0043933 macromolecular complex subunit organization
4.07 1.74e-07 GO:0006334 nucleosome assembly
1.60 2.08e-07 GO:0009059 macromolecule biosynthetic process
2.38 2.16e-07 GO:0006397 mRNA processing
2.42 2.17e-07 GO:0034622 cellular macromolecular complex assembly
1.61 2.36e-07 GO:0006996 organelle organization
2.53 4.41e-07 GO:0051325 interphase
3.80 4.81e-07 GO:0034728 nucleosome organization
3.35 5.81e-07 GO:0006333 chromatin assembly or disassembly
2.53 6.81e-07 GO:0008380 RNA splicing
2.02 7.09e-07 GO:0051726 regulation of cell cycle
1.95 9.38e-07 GO:0065003 macromolecular complex assembly
2.13 1.05e-06 GO:0006974 response to DNA damage stimulus
1.69 1.67e-06 GO:0044085 cellular component biogenesis
2.48 2.03e-06 GO:0051329 interphase of mitotic cell cycle
2.81 4.43e-06 GO:0000375 RNA splicing, via transesterification reactions
2.82 6.84e-06 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.82 6.84e-06 GO:0000398 nuclear mRNA splicing, via spliceosome
3.44 1.21e-05 GO:0051320 S phase
3.11 1.46e-05 GO:0000082 G1/S transition of mitotic cell cycle
1.42 1.83e-05 GO:0044249 cellular biosynthetic process
1.68 2.21e-05 GO:0022607 cellular component assembly
2.26 3.12e-05 GO:0010564 regulation of cell cycle process
3.38 3.46e-05 GO:0000084 S phase of mitotic cell cycle
1.33 4.95e-05 GO:0060255 regulation of macromolecule metabolic process
2.36 5.03e-05 GO:0000280 nuclear division
2.36 5.03e-05 GO:0007067 mitosis
2.55 8.50e-05 GO:0071156 regulation of cell cycle arrest
2.58 8.68e-05 GO:0000075 cell cycle checkpoint
2.29 1.27e-04 GO:0000087 M phase of mitotic cell cycle
1.39 1.28e-04 GO:0009058 biosynthetic process
2.28 1.42e-04 GO:0048285 organelle fission
1.31 1.60e-04 GO:0031323 regulation of cellular metabolic process
2.67 1.82e-04 GO:0006260 DNA replication
2.00 1.90e-04 GO:0006325 chromatin organization
1.77 2.20e-04 GO:0071844 cellular component assembly at cellular level
2.17 2.82e-04 GO:0006281 DNA repair
2.90 3.74e-04 GO:0006310 DNA recombination
1.71 3.80e-04 GO:0033554 cellular response to stress
1.29 8.36e-04 GO:0080090 regulation of primary metabolic process
6.19 9.01e-04 GO:0031055 chromatin remodeling at centromere
1.27 9.46e-04 GO:0019222 regulation of metabolic process
1.36 1.58e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.06 2.00e-03 GO:0051301 cell division
1.60 2.17e-03 GO:0032774 RNA biosynthetic process
1.34 3.37e-03 GO:0010556 regulation of macromolecule biosynthetic process
5.30 5.88e-03 GO:0006271 DNA strand elongation involved in DNA replication
1.16 7.23e-03 GO:0050794 regulation of cellular process
3.29 7.26e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.59 1.20e-02 GO:0006351 transcription, DNA-dependent
4.95 1.30e-02 GO:0022616 DNA strand elongation
1.35 1.33e-02 GO:0048523 negative regulation of cellular process
1.31 1.37e-02 GO:0010468 regulation of gene expression
1.15 1.60e-02 GO:0050789 regulation of biological process
7.88 1.73e-02 GO:0071897 DNA biosynthetic process
1.30 2.24e-02 GO:0031326 regulation of cellular biosynthetic process
1.29 2.26e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.55 3.17e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.52 3.36e-02 GO:0009892 negative regulation of metabolic process
2.73 3.36e-02 GO:0007126 meiosis
2.73 3.36e-02 GO:0051327 M phase of meiotic cell cycle
5.52 3.38e-02 GO:0006336 DNA replication-independent nucleosome assembly
5.52 3.38e-02 GO:0034080 CenH3-containing nucleosome assembly at centromere
5.52 3.38e-02 GO:0034724 DNA replication-independent nucleosome organization
1.29 3.45e-02 GO:0009889 regulation of biosynthetic process
1.31 3.78e-02 GO:0048519 negative regulation of biological process
2.70 3.91e-02 GO:0051321 meiotic cell cycle
1.32 4.14e-02 GO:0051252 regulation of RNA metabolic process
4.82 4.62e-02 GO:0043044 ATP-dependent chromatin remodeling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 4.33e-36 GO:0043226 organelle
1.31 8.99e-36 GO:0043229 intracellular organelle
1.54 1.21e-34 GO:0005634 nucleus
1.34 3.57e-33 GO:0043227 membrane-bounded organelle
1.34 4.66e-33 GO:0043231 intracellular membrane-bounded organelle
1.23 7.51e-31 GO:0044424 intracellular part
1.22 1.48e-30 GO:0005622 intracellular
1.95 6.27e-29 GO:0044428 nuclear part
1.90 1.41e-27 GO:0070013 intracellular organelle lumen
1.87 1.23e-26 GO:0031974 membrane-enclosed lumen
1.87 2.04e-26 GO:0043233 organelle lumen
2.00 3.10e-26 GO:0031981 nuclear lumen
1.46 2.95e-25 GO:0044446 intracellular organelle part
1.45 6.04e-25 GO:0044422 organelle part
2.15 2.19e-23 GO:0005654 nucleoplasm
2.71 3.92e-19 GO:0005694 chromosome
1.52 6.71e-17 GO:0032991 macromolecular complex
2.74 2.44e-16 GO:0044427 chromosomal part
1.56 7.08e-14 GO:0043228 non-membrane-bounded organelle
1.56 7.08e-14 GO:0043232 intracellular non-membrane-bounded organelle
2.19 6.14e-13 GO:0044451 nucleoplasm part
3.01 1.66e-10 GO:0000785 chromatin
2.29 2.93e-10 GO:0030529 ribonucleoprotein complex
2.83 9.60e-08 GO:0000228 nuclear chromosome
2.70 4.56e-07 GO:0016604 nuclear body
2.94 8.62e-07 GO:0044454 nuclear chromosome part
1.06 1.30e-06 GO:0044464 cell part
1.06 1.35e-06 GO:0005623 cell
1.37 1.59e-06 GO:0043234 protein complex
3.48 1.04e-05 GO:0032993 protein-DNA complex
1.14 2.09e-04 GO:0005737 cytoplasm
2.64 1.80e-03 GO:0005681 spliceosomal complex
3.13 2.73e-03 GO:0000790 nuclear chromatin
3.48 3.35e-03 GO:0000786 nucleosome
2.51 4.75e-03 GO:0000793 condensed chromosome
9.00 4.86e-03 GO:0035098 ESC/E(Z) complex
2.46 7.03e-03 GO:0000775 chromosome, centromeric region
1.72 9.17e-03 GO:0005730 nucleolus
2.24 1.07e-02 GO:0005819 spindle
5.69 1.37e-02 GO:0031519 PcG protein complex
1.59 1.55e-02 GO:0015630 microtubule cytoskeleton
4.01 2.14e-02 GO:0005657 replication fork

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.59 1.47e-19 GO:0003676 nucleic acid binding
1.27 6.60e-14 GO:0005515 protein binding
1.56 2.06e-11 GO:0003677 DNA binding
1.13 1.76e-10 GO:0005488 binding
1.95 1.68e-09 GO:0003723 RNA binding
1.40 2.60e-05 GO:0000166 nucleotide binding
1.63 5.61e-05 GO:0030528 transcription regulator activity
2.56 1.36e-04 GO:0043566 structure-specific DNA binding
2.70 1.06e-03 GO:0003690 double-stranded DNA binding
3.33 1.42e-03 GO:0003729 mRNA binding
1.52 5.79e-03 GO:0001071 nucleic acid binding transcription factor activity
1.52 5.79e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.98 6.02e-03 GO:0016564 transcription repressor activity
3.32 3.17e-02 GO:0003697 single-stranded DNA binding
1.77 4.66e-02 GO:0003712 transcription cofactor activity
1.77 4.99e-02 GO:0000988 protein binding transcription factor activity
1.77 4.99e-02 GO:0000989 transcription factor binding transcription factor activity