Motif ID: EHF.p2

Z-value: 1.657


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor



Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_121780835 4.818 NM_032554
GPR81
G protein-coupled receptor 81
chr13_-_113151453 3.793 NM_199162
ADPRHL1
ADP-ribosylhydrolase like 1
chr6_-_116488458 3.313 NM_002031
FRK
fyn-related kinase
chr19_+_40431678 3.227 LSR
lipolysis stimulated lipoprotein receptor
chr1_+_167604056 3.096 BLZF1
basic leucine zipper nuclear factor 1
chr19_+_40431618 2.929 LSR
lipolysis stimulated lipoprotein receptor
chr11_+_63412562 2.889 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr8_-_144887876 2.782 NM_198488
FAM83H
family with sequence similarity 83, member H
chr12_-_32940931 2.641 NM_001005242
NM_004572
PKP2

plakophilin 2

chr19_+_6415259 2.638 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr17_+_55139807 2.620 VMP1
vacuole membrane protein 1
chr17_+_55139793 2.578 VMP1
vacuole membrane protein 1
chr6_+_33347833 2.511 RPS18
ribosomal protein S18
chr8_+_144888275 2.504 LOC100128338
hypothetical LOC100128338
chr17_+_55139743 2.504 VMP1
vacuole membrane protein 1
chr1_-_205272619 2.500 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr17_+_55139792 2.499 VMP1
vacuole membrane protein 1
chr11_+_384238 2.493 PKP3
plakophilin 3
chr18_+_54039818 2.459 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr8_+_15442123 2.437 TUSC3
tumor suppressor candidate 3
chr6_+_33347776 2.417 NM_022551
RPS18
ribosomal protein S18
chr17_+_55139841 2.391 VMP1
vacuole membrane protein 1
chr15_+_21361901 2.360 MKRN3
makorin ring finger protein 3
chr2_-_160765008 2.356 ITGB6
integrin, beta 6
chr11_+_384199 2.242 NM_007183
PKP3
plakophilin 3
chr8_+_15442106 2.160 TUSC3
tumor suppressor candidate 3
chr1_-_167603623 2.089 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr2_-_220116508 2.069 NM_024536
CHPF
chondroitin polymerizing factor
chr19_-_56214765 2.057 NM_145888
KLK10
kallikrein-related peptidase 10
chr1_+_167603817 2.045 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr15_-_31147376 2.039 NM_001103184
FMN1
formin 1
chr17_+_55139644 2.032 NM_030938
VMP1
vacuole membrane protein 1
chr18_+_3443771 2.001 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr1_-_199635240 1.992 NM_005558
LAD1
ladinin 1
chr1_-_27159462 1.981 NM_152365
C1orf172
chromosome 1 open reading frame 172
chr1_-_199635057 1.971 LAD1
ladinin 1
chrX_-_40479607 1.952 MED14
mediator complex subunit 14
chr6_-_33347563 1.947 NM_022553
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr17_-_55139538 1.932 NM_016077
PTRH2
peptidyl-tRNA hydrolase 2
chr1_-_199635339 1.899 LAD1
ladinin 1
chr17_+_45965076 1.877 EPN3
epsin 3
chr19_+_40299058 1.877 FXYD3
FXYD domain containing ion transport regulator 3
chr8_+_15442100 1.875 NM_006765
NM_178234
TUSC3

tumor suppressor candidate 3

chr1_+_32460557 1.850 NM_003757
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32460600 1.836 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32460597 1.815 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr18_+_54039779 1.757 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr16_+_56211410 1.725 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56

chr1_-_32460532 1.700 TMEM234
transmembrane protein 234
chrX_-_15783015 1.679 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr8_+_82807218 1.678 NM_152284
CHMP4C
chromatin modifying protein 4C
chrX_-_40479718 1.663 NM_004229
MED14
mediator complex subunit 14
chr6_+_54819527 1.651 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr1_-_32460526 1.641 TMEM234
transmembrane protein 234
chr1_+_202097346 1.638 SNRPE
small nuclear ribonucleoprotein polypeptide E
chrX_-_40479893 1.624 MED14
mediator complex subunit 14
chr6_-_33347417 1.603 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr2_-_160764819 1.591 NM_000888
ITGB6
integrin, beta 6
chr1_+_203740306 1.583 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr1_-_164004730 1.568 NM_019026
TMCO1
transmembrane and coiled-coil domains 1
chr1_-_43523825 1.543 NM_182517
NM_001164829
C1orf210

chromosome 1 open reading frame 210

chr6_-_32251864 1.533 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr1_-_152797820 1.531 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr6_-_31728447 1.527 NM_004639
NM_080702
NM_080703
BAG6


BCL2-associated athanogene 6


chrX_-_153428621 1.521 G6PD
glucose-6-phosphate dehydrogenase
chr1_+_203740391 1.508 CDK18
cyclin-dependent kinase 18
chr5_+_140051404 1.487 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr16_+_65790514 1.487 NM_024712
ELMO3
engulfment and cell motility 3
chr11_-_128399218 1.484 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_+_199130571 1.483 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr1_-_40496161 1.471


chr11_+_46679140 1.466 NM_001184751
ZNF408
zinc finger protein 408
chr1_-_164004611 1.465 TMCO1
transmembrane and coiled-coil domains 1
chr11_+_65526462 1.462 BANF1
barrier to autointegration factor 1
chr2_-_36384 1.456 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr1_-_43410235 1.455 EBNA1BP2
EBNA1 binding protein 2
chr4_-_84031358 1.426 NM_001191049
SEC31A
SEC31 homolog A (S. cerevisiae)
chr3_+_11242666 1.423 NM_001098211
HRH1
histamine receptor H1
chr6_-_32251877 1.422 NM_006411
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr2_+_174968701 1.419 NM_001193528
NM_024583
SCRN3

secernin 3

chr4_-_9632192 1.407 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chrX_+_79477658 1.405 NM_001170574
FAM46D
family with sequence similarity 46, member D
chrX_-_119578899 1.403 CUL4B
cullin 4B
chr1_+_202097386 1.397 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr1_-_152797760 1.393 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr2_-_220116062 1.390 NM_001195731
CHPF
chondroitin polymerizing factor
chr1_+_164004789 1.387 LOC100147773
hypothetical LOC100147773
chr10_+_12278213 1.386 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr6_-_32251773 1.381 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr1_+_202097355 1.380 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr6_+_31623331 1.379 NM_001144961
NM_005007
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr17_-_53849888 1.379 RNF43
ring finger protein 43
chr1_-_32460417 1.373 NM_019118
TMEM234
transmembrane protein 234
chr3_-_178396892 1.368 TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr11_+_65526349 1.367 BANF1
barrier to autointegration factor 1
chr2_+_157822355 1.364 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr16_+_67723988 1.359 NM_032830
CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr4_-_84031349 1.355 SEC31A
SEC31 homolog A (S. cerevisiae)
chr5_-_140051137 1.354 NM_002109
HARS
histidyl-tRNA synthetase
chr1_-_20860468 1.349 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr10_+_12278185 1.348 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr4_-_84031362 1.348 SEC31A
SEC31 homolog A (S. cerevisiae)
chr1_-_71319265 1.345 ZRANB2
zinc finger, RAN-binding domain containing 2
chrX_-_131179598 1.342 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr1_-_20860483 1.341 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr1_-_20860454 1.337 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr5_+_140051325 1.333 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr8_-_95634845 1.330 NM_015496
NM_183009
KIAA1429

KIAA1429

chr11_+_65526277 1.329 BANF1
barrier to autointegration factor 1
chr1_-_20860500 1.328 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr20_-_17986520 1.327 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr2_+_174968751 1.326 SCRN3
secernin 3
chr12_+_88268845 1.326 LOC100131490
hypothetical LOC100131490
chr19_+_40431359 1.324 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr1_+_40279023 1.317 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_31728405 1.312 BAG6
BCL2-associated athanogene 6
chr19_+_61624 1.312 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr10_+_12278200 1.311 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr1_-_20860547 1.307 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr14_+_20580224 1.301 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chrX_-_15782826 1.299


chr3_+_9809776 1.298 NM_001198780
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr1_+_40279036 1.294 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr4_-_84031329 1.289 SEC31A
SEC31 homolog A (S. cerevisiae)
chr4_-_84031294 1.286 SEC31A
SEC31 homolog A (S. cerevisiae)
chr5_+_2805261 1.283 NM_178569
C5orf38
chromosome 5 open reading frame 38
chr11_-_46678691 1.282 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr16_+_67724039 1.276 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr3_-_12561962 1.272 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr1_-_20860571 1.270 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr6_+_126282078 1.269 NCOA7
nuclear receptor coactivator 7
chr11_+_93394025 1.268 NM_001098672
HEPHL1
hephaestin-like 1
chr1_+_38046005 1.266 C1orf122
chromosome 1 open reading frame 122
chr1_+_40279010 1.264 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_31728418 1.263 BAG6
BCL2-associated athanogene 6
chr16_+_67724023 1.263 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr1_-_20860524 1.261 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr1_-_20860372 1.257 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chrX_+_150316351 1.256 VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr16_-_67723971 1.254 CHTF8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr4_-_84031396 1.250 NM_001077206
NM_001077207
NM_001077208
NM_016211
NM_014933
SEC31A




SEC31 homolog A (S. cerevisiae)




chr3_+_151747204 1.248 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr1_+_40278971 1.237 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr10_-_12278026 1.236 NM_014142
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr3_-_13896618 1.235 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chrX_+_153429022 1.230 IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chrX_+_153428755 1.229 NM_001099857
NM_001145255
IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

chr1_-_152797767 1.226 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr1_+_40496317 1.222 NM_005857
ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr6_-_31617704 1.219 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chrX_-_67569894 1.212 NM_002547
OPHN1
oligophrenin 1
chr14_+_20636935 1.212 NM_001146683
C14orf176
chromosome 14 open reading frame 176
chr12_-_51629874 1.207 KRT8
keratin 8
chr7_+_107171809 1.207 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chrX_+_153429042 1.206 IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr1_+_9926072 1.202 NM_022787
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr1_-_20860443 1.200 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr9_+_676640 1.198


chr6_-_11887265 1.196 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr11_+_117735530 1.193 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr7_-_91713044 1.186 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr12_+_11694172 1.185 ETV6
ets variant 6
chr1_+_40278993 1.184 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr1_-_9925908 1.182 LZIC
leucine zipper and CTNNBIP1 domain containing
chr11_+_71469340 1.169 NM_001145307
NM_145309
LRTOMT

leucine rich transmembrane and 0-methyltransferase domain containing

chrX_-_153428968 1.169 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr1_-_20860534 1.166 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chrX_-_15782859 1.158 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chrX_+_131179886 1.154


chr22_+_38228234 1.149 SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like
chr8_-_104496444 1.147 SLC25A32
solute carrier family 25, member 32
chr6_-_31728363 1.140 BAG6
BCL2-associated athanogene 6
chr16_-_67723993 1.138 NM_001039690
CHTF8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr6_-_43592670 1.131 YIPF3
Yip1 domain family, member 3
chr4_+_155884564 1.129 LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr11_+_117735529 1.129 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr22_+_38228194 1.128 NM_019008
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like
chr16_-_67723928 1.127 CHTF8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr16_+_3102556 1.125 NM_001042428
NM_003456
ZNF205

zinc finger protein 205

chr11_+_117735502 1.124 NM_004788
UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chrX_-_15782803 1.118 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr6_+_30958672 1.104 DDR1
discoidin domain receptor tyrosine kinase 1
chr7_+_150442652 1.090 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr5_-_40871040 1.089 RPL37
SNORD72
ribosomal protein L37
small nucleolar RNA, C/D box 72
chr19_+_40431122 1.089 LSR
lipolysis stimulated lipoprotein receptor
chr2_-_174968595 1.087 NM_004882
CIR1
corepressor interacting with RBPJ, 1
chrX_-_15782792 1.086 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_26553168 1.084 NM_001039775
AIM1L
absent in melanoma 1-like
chr5_+_140051198 1.082 NM_012208
HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chrX_-_15782842 1.079 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr5_+_10303281 1.078 NM_012073
CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr6_+_43592812 1.078 POLR1C
polymerase (RNA) I polypeptide C, 30kDa
chr7_-_135312574 1.077 MTPN
myotrophin
chr6_+_43592758 1.077 NM_004875
NM_203290
POLR1C

polymerase (RNA) I polypeptide C, 30kDa

chr16_-_70400040 1.077 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr1_+_38046055 1.077 NM_001142726
NM_198446
C1orf122

chromosome 1 open reading frame 122

chr6_-_29081015 1.066 NM_001010877
ZNF311
zinc finger protein 311
chr11_-_46678736 1.065 ARHGAP1
Rho GTPase activating protein 1
chr5_+_87600485 1.064 LOC100505894
hypothetical LOC100505894
chr20_+_54477119 1.063 C20orf43
chromosome 20 open reading frame 43

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.40 2.72e-30 GO:0044260 cellular macromolecule metabolic process
1.34 6.49e-26 GO:0043170 macromolecule metabolic process
1.59 5.75e-22 GO:0010467 gene expression
1.53 2.75e-21 GO:0090304 nucleic acid metabolic process
1.25 1.24e-19 GO:0044237 cellular metabolic process
1.44 3.36e-19 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 3.42e-18 GO:0016070 RNA metabolic process
1.97 1.11e-17 GO:0006396 RNA processing
2.03 2.77e-16 GO:0016071 mRNA metabolic process
1.42 1.70e-15 GO:0044267 cellular protein metabolic process
1.22 1.80e-15 GO:0044238 primary metabolic process
1.20 3.46e-15 GO:0008152 metabolic process
2.61 1.16e-13 GO:0022613 ribonucleoprotein complex biogenesis
2.58 1.88e-13 GO:0000375 RNA splicing, via transesterification reactions
1.34 2.95e-13 GO:0034641 cellular nitrogen compound metabolic process
2.58 4.44e-13 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.58 4.44e-13 GO:0000398 nuclear mRNA splicing, via spliceosome
2.08 1.23e-12 GO:0006397 mRNA processing
1.32 1.50e-12 GO:0006807 nitrogen compound metabolic process
2.21 3.28e-12 GO:0008380 RNA splicing
2.48 3.91e-12 GO:0071843 cellular component biogenesis at cellular level
2.19 5.44e-12 GO:0006412 translation
1.47 9.93e-12 GO:0034645 cellular macromolecule biosynthetic process
1.46 1.26e-11 GO:0009059 macromolecule biosynthetic process
1.29 5.37e-11 GO:0071840 cellular component organization or biogenesis
1.96 1.59e-10 GO:0016032 viral reproduction
1.32 1.83e-10 GO:0019538 protein metabolic process
1.33 2.44e-10 GO:0071841 cellular component organization or biogenesis at cellular level
2.72 1.89e-09 GO:0042254 ribosome biogenesis
1.80 2.86e-09 GO:0044265 cellular macromolecule catabolic process
1.72 8.53e-09 GO:0009057 macromolecule catabolic process
1.96 5.00e-08 GO:0051603 proteolysis involved in cellular protein catabolic process
1.91 6.74e-08 GO:0030163 protein catabolic process
1.94 6.94e-08 GO:0044257 cellular protein catabolic process
1.57 7.55e-08 GO:0015031 protein transport
1.50 1.00e-07 GO:0008104 protein localization
1.97 1.03e-07 GO:0006511 ubiquitin-dependent protein catabolic process
1.56 1.22e-07 GO:0045184 establishment of protein localization
1.95 1.44e-07 GO:0019941 modification-dependent protein catabolic process
1.94 2.16e-07 GO:0043632 modification-dependent macromolecule catabolic process
1.24 8.34e-07 GO:0016043 cellular component organization
1.09 1.02e-06 GO:0009987 cellular process
1.28 2.24e-06 GO:0071842 cellular component organization at cellular level
1.54 4.80e-06 GO:0046907 intracellular transport
1.40 8.25e-06 GO:0033036 macromolecule localization
1.90 1.37e-05 GO:0010608 posttranscriptional regulation of gene expression
2.20 1.75e-05 GO:0010498 proteasomal protein catabolic process
2.20 1.75e-05 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.52 2.19e-05 GO:0016192 vesicle-mediated transport
1.27 4.08e-05 GO:0044249 cellular biosynthetic process
1.63 5.16e-05 GO:0006974 response to DNA damage stimulus
1.40 7.89e-05 GO:0044248 cellular catabolic process
1.77 8.21e-05 GO:0070647 protein modification by small protein conjugation or removal
1.42 8.23e-05 GO:0007049 cell cycle
1.35 8.35e-05 GO:0009056 catabolic process
1.26 8.37e-05 GO:0009058 biosynthetic process
1.33 9.58e-05 GO:0006996 organelle organization
1.37 1.93e-04 GO:0051641 cellular localization
1.83 2.90e-04 GO:0034660 ncRNA metabolic process
2.51 3.17e-04 GO:0071826 ribonucleoprotein complex subunit organization
1.80 4.41e-04 GO:0032446 protein modification by small protein conjugation
1.38 5.82e-04 GO:0051649 establishment of localization in cell
1.36 6.56e-04 GO:0044085 cellular component biogenesis
2.51 7.50e-04 GO:0022618 ribonucleoprotein complex assembly
2.42 8.53e-04 GO:0006364 rRNA processing
1.80 1.03e-03 GO:0016567 protein ubiquitination
2.36 1.21e-03 GO:0016072 rRNA metabolic process
1.56 1.60e-03 GO:0034621 cellular macromolecular complex subunit organization
1.51 1.90e-03 GO:0000278 mitotic cell cycle
1.42 2.67e-03 GO:0033554 cellular response to stress
1.26 3.53e-03 GO:0043412 macromolecule modification
2.46 4.53e-03 GO:0006353 transcription termination, DNA-dependent
2.41 4.77e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.94 6.05e-03 GO:0006417 regulation of translation
1.68 6.68e-03 GO:0051329 interphase of mitotic cell cycle
2.21 6.68e-03 GO:0006414 translational elongation
1.68 6.89e-03 GO:0051325 interphase
2.55 7.10e-03 GO:0071158 positive regulation of cell cycle arrest
2.15 8.20e-03 GO:0000084 S phase of mitotic cell cycle
2.35 8.84e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.98 1.10e-02 GO:0000082 G1/S transition of mitotic cell cycle
2.11 1.34e-02 GO:0051320 S phase
1.99 1.57e-02 GO:0019058 viral infectious cycle
2.29 1.59e-02 GO:0051351 positive regulation of ligase activity
1.39 1.62e-02 GO:0022402 cell cycle process
1.25 1.86e-02 GO:0006464 protein modification process
1.82 1.91e-02 GO:0034470 ncRNA processing
2.38 2.03e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.37 2.36e-02 GO:0043933 macromolecular complex subunit organization
1.81 2.99e-02 GO:0022411 cellular component disassembly
1.81 2.99e-02 GO:0071845 cellular component disassembly at cellular level
1.43 3.00e-02 GO:0051726 regulation of cell cycle
1.45 3.08e-02 GO:0006259 DNA metabolic process
2.46 3.35e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.46 3.35e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.46 3.35e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.46 3.35e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.46 3.35e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.46 3.35e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.46 3.35e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.46 3.35e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.28 3.74e-02 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.47 3.84e-02 GO:0034613 cellular protein localization
1.40 4.44e-02 GO:0022403 cell cycle phase
2.13 4.45e-02 GO:0051340 regulation of ligase activity
2.19 4.77e-02 GO:0006415 translational termination
2.05 4.85e-02 GO:0032984 macromolecular complex disassembly
2.05 4.85e-02 GO:0034623 cellular macromolecular complex disassembly
2.22 4.88e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.25 4.95e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.25 4.95e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.25 4.95e-02 GO:0071779 G1/S transition checkpoint

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.40e-39 GO:0044424 intracellular part
1.22 6.75e-39 GO:0043229 intracellular organelle
1.22 8.84e-39 GO:0043226 organelle
1.17 2.69e-38 GO:0005622 intracellular
1.24 2.26e-36 GO:0043231 intracellular membrane-bounded organelle
1.24 2.86e-36 GO:0043227 membrane-bounded organelle
1.34 5.96e-33 GO:0044446 intracellular organelle part
1.33 2.53e-31 GO:0044422 organelle part
1.55 9.41e-27 GO:0031974 membrane-enclosed lumen
1.56 1.46e-25 GO:0044428 nuclear part
1.54 5.00e-25 GO:0043233 organelle lumen
1.54 1.63e-24 GO:0070013 intracellular organelle lumen
1.59 6.24e-23 GO:0031981 nuclear lumen
1.28 3.99e-22 GO:0005634 nucleus
2.15 3.13e-21 GO:0030529 ribonucleoprotein complex
1.19 1.05e-19 GO:0005737 cytoplasm
1.35 1.25e-18 GO:0032991 macromolecular complex
1.23 2.36e-16 GO:0044444 cytoplasmic part
1.54 2.80e-13 GO:0005654 nucleoplasm
1.35 8.48e-13 GO:0043228 non-membrane-bounded organelle
1.35 8.48e-13 GO:0043232 intracellular non-membrane-bounded organelle
1.38 3.64e-11 GO:0005829 cytosol
1.83 6.97e-11 GO:0005730 nucleolus
2.50 1.83e-08 GO:0005681 spliceosomal complex
2.93 7.08e-08 GO:0071013 catalytic step 2 spliceosome
1.26 1.01e-07 GO:0043234 protein complex
2.85 9.46e-06 GO:0030117 membrane coat
2.85 9.46e-06 GO:0048475 coated membrane
1.99 5.25e-05 GO:0005840 ribosome
1.26 9.92e-05 GO:0031090 organelle membrane
1.47 1.04e-04 GO:0044451 nucleoplasm part
1.04 2.90e-04 GO:0044464 cell part
1.04 3.05e-04 GO:0005623 cell
3.05 1.10e-03 GO:0030120 vesicle coat
2.67 1.77e-03 GO:0005798 Golgi-associated vesicle
2.49 3.12e-03 GO:0000502 proteasome complex
1.94 4.62e-03 GO:0000151 ubiquitin ligase complex
1.95 1.28e-02 GO:0016607 nuclear speck
1.68 1.59e-02 GO:0016604 nuclear body
2.36 1.95e-02 GO:0015934 large ribosomal subunit
1.26 2.40e-02 GO:0005739 mitochondrion
2.20 2.58e-02 GO:0022626 cytosolic ribosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 7.20e-19 GO:0005515 protein binding
1.83 7.44e-19 GO:0003723 RNA binding
1.28 9.90e-11 GO:0003676 nucleic acid binding
1.08 3.11e-08 GO:0005488 binding
2.63 1.95e-05 GO:0008135 translation factor activity, nucleic acid binding
3.06 8.63e-04 GO:0043021 ribonucleoprotein binding
2.04 8.76e-04 GO:0004386 helicase activity
1.99 1.19e-03 GO:0003735 structural constituent of ribosome
1.22 1.51e-03 GO:0000166 nucleotide binding
2.15 2.80e-03 GO:0008026 ATP-dependent helicase activity
2.15 2.80e-03 GO:0070035 purine NTP-dependent helicase activity
3.96 3.98e-03 GO:0043022 ribosome binding
1.69 1.28e-02 GO:0019787 small conjugating protein ligase activity
1.70 1.54e-02 GO:0004842 ubiquitin-protein ligase activity
2.61 1.72e-02 GO:0003743 translation initiation factor activity
1.21 4.35e-02 GO:0017076 purine nucleotide binding
1.21 4.60e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.34 4.74e-02 GO:0017111 nucleoside-triphosphatase activity