Motif ID: ELF1,2,4.p2

Z-value: 1.333


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)



Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_110653407 2.594 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr13_-_30089509 2.250 HMGB1
high-mobility group box 1
chr14_+_62740878 2.244 NM_020663
RHOJ
ras homolog gene family, member J
chr19_+_43447262 2.103 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr7_+_150044530 2.092 NM_130759
GIMAP1
GTPase, IMAP family member 1
chr5_+_61910318 2.031 NM_181506
LRRC70
leucine rich repeat containing 70
chr5_-_124108672 1.993 NM_020747
ZNF608
zinc finger protein 608
chr3_-_184756101 1.880 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr4_+_91035025 1.842 NM_007351
MMRN1
multimerin 1
chrX_+_114734074 1.807 NM_001136025
NM_001172335
PLS3

plastin 3

chr11_-_72111027 1.679 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr9_+_115303527 1.542 NM_130795
RGS3
regulator of G-protein signaling 3
chr10_+_8137356 1.512 GATA3
GATA binding protein 3
chr1_+_26358097 1.496 NM_024869
GRRP1
glycine/arginine rich protein 1
chr7_-_143622188 1.478 ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_+_167604056 1.459 BLZF1
basic leucine zipper nuclear factor 1
chr3_+_29297806 1.458 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr17_-_74244539 1.411


chr22_-_34566210 1.404 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_-_120878910 1.403 NM_005694
COX17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr17_-_18890963 1.386 NM_006613
GRAP
GRB2-related adaptor protein
chr7_-_143523582 1.384 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr8_-_29262240 1.370 NM_057158
DUSP4
dual specificity phosphatase 4
chr7_-_143622233 1.345 ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chrX_-_50403412 1.344 SHROOM4
shroom family member 4
chr7_+_149842850 1.318 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr22_-_34566276 1.306 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr13_+_30089829 1.304 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr7_+_143683365 1.301 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_+_28637247 1.296 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr14_-_37795001 1.269 CLEC14A
C-type lectin domain family 14, member A
chr3_-_113763049 1.266 NM_022488
ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr12_-_52939636 1.232 NM_001127321
CBX5
chromobox homolog 5
chr2_+_237143118 1.230 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr22_-_34566367 1.219 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr3_+_195889845 1.204 FAM43A
family with sequence similarity 43, member A
chr12_-_368517 1.185 KDM5A
lysine (K)-specific demethylase 5A
chr10_+_12278213 1.180 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr3_+_44665220 1.176 NM_003420
ZNF35
zinc finger protein 35
chr1_+_167603817 1.171 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr14_-_74249492 1.168 NM_001039479
KIAA0317
KIAA0317
chr10_-_12278026 1.165 NM_014142
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr5_+_78944151 1.153 PAPD4
PAP associated domain containing 4
chr1_-_152797707 1.145 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr10_-_112668679 1.140 NM_001195306
BBIP1
BBSome interacting protein 1
chr8_-_78074851 1.139 NM_000318
NM_001079867
PEX2

peroxisomal biogenesis factor 2

chr12_+_11694172 1.133 ETV6
ets variant 6
chr14_-_37795290 1.132 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr19_+_43447078 1.130 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_-_152797760 1.119 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr6_-_76050837 1.114


chr1_+_150428404 1.113


chr19_+_39860398 1.103 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr10_+_129735796 1.102 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr19_-_53935648 1.102 NM_017805
RASIP1
Ras interacting protein 1
chr6_-_56824672 1.099 DST
dystonin
chr11_-_117628211 1.091 NM_198275
MPZL3
myelin protein zero-like 3
chr15_+_91248706 1.089 CHD2
chromodomain helicase DNA binding protein 2
chr2_+_24152799 1.089


chrX_-_153428621 1.087 G6PD
glucose-6-phosphate dehydrogenase
chr11_-_60953848 1.085 NM_024811
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr21_+_25856311 1.084 MIR155HG
MIR155 host gene (non-protein coding)
chr9_-_35738875 1.078 GBA2
glucosidase, beta (bile acid) 2
chr14_+_74249599 1.075 NM_015962
FCF1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr10_-_112668892 1.073 NM_001195304
NM_001195305
NM_001195307
BBIP1


BBSome interacting protein 1


chr10_+_12278185 1.070 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr4_-_153820535 1.064 NM_152680
TMEM154
transmembrane protein 154
chr1_-_159369081 1.058 NM_001039711
NM_032998
DEDD

death effector domain containing

chr15_+_79376295 1.039 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr1_-_167603623 1.034 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr12_-_6668880 1.029 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr1_+_220953278 1.027 BROX
BRO1 domain and CAAX motif containing
chr4_-_99283323 1.025 NM_174952
C4orf37
chromosome 4 open reading frame 37
chr11_+_60954096 1.023 SDHAF2
succinate dehydrogenase complex assembly factor 2
chr7_-_32897714 1.017 KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr10_+_12278200 1.015 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr3_-_49424322 1.011 RHOA
ras homolog gene family, member A
chr1_-_159369041 1.008 DEDD
death effector domain containing
chr5_-_102483680 1.006 NM_017676
GIN1
gypsy retrotransposon integrase 1
chr1_+_220953351 1.005 BROX
BRO1 domain and CAAX motif containing
chr14_+_101346032 0.995 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr11_+_128069165 0.989 FLI1
Friend leukemia virus integration 1
chr1_+_38046404 0.987 C1orf122
chromosome 1 open reading frame 122
chr14_-_56805118 0.984


chrX_-_153908408 0.981 F8
coagulation factor VIII, procoagulant component
chr14_+_60858151 0.978 NM_006255
PRKCH
protein kinase C, eta
chrX_-_131179598 0.976 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr9_-_21325239 0.975 NM_018847
KLHL9
kelch-like 9 (Drosophila)
chr11_+_128069183 0.969 FLI1
Friend leukemia virus integration 1
chr1_-_152797767 0.965 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr1_-_152797820 0.964 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr13_-_51878235 0.964 THSD1
thrombospondin, type I, domain containing 1
chr18_-_50004770 0.963 MBD2
methyl-CpG binding domain protein 2
chr19_-_55008172 0.963 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr5_-_82408917 0.962 TMEM167A
transmembrane protein 167A
chr11_+_65027721 0.959


chr11_-_77383359 0.950 NM_033547
INTS4
integrator complex subunit 4
chrX_+_64804318 0.946 MSN
moesin
chrX_+_64804235 0.945 NM_002444
MSN
moesin
chr2_-_189752575 0.945 NM_000393
COL5A2
collagen, type V, alpha 2
chr3_-_49424361 0.940 RHOA
ras homolog gene family, member A
chrX_+_64804259 0.936 MSN
moesin
chrX_+_15428820 0.935 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr17_-_60208083 0.932 LOC146880
hypothetical LOC146880
chr7_+_134114701 0.931 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr1_+_155130146 0.931 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr7_+_134114912 0.929 CALD1
caldesmon 1
chr19_+_43446937 0.928 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr3_+_151747204 0.928 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr8_+_42515873 0.925 NM_138436
NM_001135674
NM_001135675
C8orf40


chromosome 8 open reading frame 40


chr11_+_128069203 0.925 FLI1
Friend leukemia virus integration 1
chr11_-_60954031 0.924 NM_001136040
NM_001142565
CPSF7

cleavage and polyadenylation specific factor 7, 59kDa

chrX_+_153908426 0.922 FUNDC2
FUN14 domain containing 2
chr11_+_60954150 0.917 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr10_+_44816278 0.916 NM_006963
ZNF22
zinc finger protein 22 (KOX 15)
chr11_-_77383307 0.916 INTS4
integrator complex subunit 4
chr9_-_129656581 0.915 ENG
endoglin
chr5_+_78944052 0.914 PAPD4
PAP associated domain containing 4
chr12_+_12829807 0.912 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr19_+_3129735 0.907 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr15_-_90999606 0.907 NM_207446
FAM174B
family with sequence similarity 174, member B
chr6_-_42293577 0.906 MRPS10
mitochondrial ribosomal protein S10
chr5_-_82409009 0.903 NM_174909
TMEM167A
transmembrane protein 167A
chr3_+_185515543 0.902 NM_182917
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr9_-_129656413 0.900 ENG
endoglin
chr6_-_42293581 0.899 NM_018141
MRPS10
mitochondrial ribosomal protein S10
chr3_-_113763217 0.893 ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chrX_-_40479607 0.893 MED14
mediator complex subunit 14
chr11_+_128068982 0.891 NM_002017
FLI1
Friend leukemia virus integration 1
chr19_-_42098919 0.883 NM_001037232
ZNF829
zinc finger protein 829
chr8_-_11096257 0.878 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr12_-_74191649 0.876 KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr3_+_9809776 0.876 NM_001198780
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr19_+_44266784 0.876 NM_001004318
PAPL
iron/zinc purple acid phosphatase-like protein
chr8_-_103735194 0.874 NM_001032282
KLF10
Kruppel-like factor 10
chr1_+_84382575 0.870 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_+_12277935 0.866 NM_006023
CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr12_+_368774 0.864 NM_001130147
NM_001130148
CCDC77

coiled-coil domain containing 77

chrX_-_40479893 0.864 MED14
mediator complex subunit 14
chr12_-_74191607 0.857 KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr5_-_112658200 0.856 MCC
mutated in colorectal cancers
chr12_-_74191658 0.853 KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr8_-_59734474 0.853 NM_001144772
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr3_-_49424404 0.852 RHOA
ras homolog gene family, member A
chr13_-_44813203 0.852 TPT1
tumor protein, translationally-controlled 1
chrX_+_153428755 0.850 NM_001099857
NM_001145255
IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

chr2_-_24152813 0.849 NM_016047
SF3B14
splicing factor 3B, 14 kDa subunit
chr5_+_78943998 0.846 NM_001114393
NM_001114394
NM_173797
PAPD4


PAP associated domain containing 4


chr7_+_134114957 0.845 CALD1
caldesmon 1
chr9_+_99435900 0.844 NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr5_+_82409072 0.843 NM_003401
NM_022406
NM_022550
XRCC4


X-ray repair complementing defective repair in Chinese hamster cells 4


chr14_+_101345878 0.842 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr1_-_38046270 0.833 YRDC
yrdC domain containing (E. coli)
chr3_-_49424380 0.833 RHOA
ras homolog gene family, member A
chr11_+_128069340 0.831 FLI1
Friend leukemia virus integration 1
chr5_+_102483856 0.830 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr10_-_103567773 0.830 MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr1_+_84382562 0.827 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr16_-_21739231 0.825 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chrX_+_153908257 0.819 NM_023934
FUNDC2
FUN14 domain containing 2
chr16_-_3567354 0.819 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr11_-_85457469 0.819 PICALM
phosphatidylinositol binding clathrin assembly protein
chr12_-_74191679 0.816 NM_007043
KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr5_-_151046638 0.815 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr2_+_33514896 0.814 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_-_52939584 0.812 NM_001127322
CBX5
chromobox homolog 5
chr9_-_129656778 0.810 ENG
endoglin
chr7_+_44207163 0.809 YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr6_-_42293564 0.806 MRPS10
mitochondrial ribosomal protein S10
chr1_+_39229474 0.805 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr3_-_49424397 0.799 RHOA
ras homolog gene family, member A
chrX_+_24621984 0.799 NM_016937
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr1_-_38046433 0.798 YRDC
yrdC domain containing (E. coli)
chr6_-_42293575 0.797 MRPS10
mitochondrial ribosomal protein S10
chr15_-_40352765 0.796 NM_001110503
NM_015497
TMEM87A

transmembrane protein 87A

chr4_-_90978469 0.795 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chrX_+_119622570 0.793 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr1_-_38046439 0.792 NM_024640
YRDC
yrdC domain containing (E. coli)
chrX_+_51562894 0.792 NM_001005332
MAGED1
melanoma antigen family D, 1
chr3_-_195874227 0.789 LSG1
large subunit GTPase 1 homolog (S. cerevisiae)
chr12_+_120840829 0.788 NM_001178003
NM_144668
WDR66

WD repeat domain 66

chr22_-_17892859 0.788 NM_001130861
NM_003277
CLDN5

claudin 5

chr3_-_195874170 0.787 LSG1
large subunit GTPase 1 homolog (S. cerevisiae)
chr19_-_39859997 0.785


chr11_+_73559900 0.784 PPME1
protein phosphatase methylesterase 1
chr14_+_77244177 0.781 NM_031210
C14orf156
chromosome 14 open reading frame 156
chr3_-_195874202 0.779 LSG1
large subunit GTPase 1 homolog (S. cerevisiae)
chr14_-_77244073 0.776 NM_006020
ALKBH1
alkB, alkylation repair homolog 1 (E. coli)
chr10_+_75174151 0.775 SEC24C
SEC24 family, member C (S. cerevisiae)
chrX_+_77052834 0.774 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr1_-_40496161 0.773


chr5_-_151046680 0.773 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_-_71262405 0.773 FOXP1
forkhead box P1
chr20_+_3818441 0.771 NM_153640
PANK2
pantothenate kinase 2
chr14_-_22458134 0.770 RBM23
RNA binding motif protein 23
chr1_+_84382529 0.766 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_91347915 0.766 NM_006980
MTERF
mitochondrial transcription termination factor
chr5_-_102926349 0.764 NM_031438
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr10_+_75174125 0.762 NM_004922
NM_198597
SEC24C

SEC24 family, member C (S. cerevisiae)

chr17_+_4922478 0.761 ZFP3
zinc finger protein 3 homolog (mouse)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.29 7.55e-31 GO:0044260 cellular macromolecule metabolic process
1.24 5.04e-25 GO:0043170 macromolecule metabolic process
1.19 9.85e-22 GO:0044237 cellular metabolic process
1.41 2.61e-20 GO:0010467 gene expression
1.31 4.86e-19 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 6.09e-18 GO:0090304 nucleic acid metabolic process
1.17 1.34e-17 GO:0044238 primary metabolic process
1.15 1.94e-16 GO:0008152 metabolic process
1.38 6.43e-16 GO:0009059 macromolecule biosynthetic process
1.37 1.13e-15 GO:0016070 RNA metabolic process
1.38 2.31e-15 GO:0034645 cellular macromolecule biosynthetic process
1.09 1.10e-14 GO:0009987 cellular process
1.28 1.16e-13 GO:0044267 cellular protein metabolic process
1.24 2.18e-12 GO:0034641 cellular nitrogen compound metabolic process
1.25 1.60e-11 GO:0071841 cellular component organization or biogenesis at cellular level
1.21 2.07e-11 GO:0071840 cellular component organization or biogenesis
1.22 2.26e-11 GO:0006807 nitrogen compound metabolic process
1.53 4.64e-10 GO:0006396 RNA processing
1.25 7.15e-10 GO:0044249 cellular biosynthetic process
1.54 1.59e-09 GO:0000278 mitotic cell cycle
1.74 3.17e-09 GO:0048285 organelle fission
1.24 3.38e-09 GO:0009058 biosynthetic process
1.21 4.17e-09 GO:0019538 protein metabolic process
1.30 4.43e-09 GO:0006996 organelle organization
1.39 6.18e-09 GO:0007049 cell cycle
1.19 1.64e-08 GO:0016043 cellular component organization
1.43 2.21e-08 GO:0022402 cell cycle process
1.22 2.65e-08 GO:0071842 cellular component organization at cellular level
1.71 3.19e-08 GO:0000087 M phase of mitotic cell cycle
1.70 3.51e-08 GO:0006412 translation
1.72 3.71e-08 GO:0000280 nuclear division
1.72 3.71e-08 GO:0007067 mitosis
1.46 6.68e-08 GO:0022403 cell cycle phase
1.31 9.33e-07 GO:0051641 cellular localization
1.40 1.17e-06 GO:0046907 intracellular transport
1.56 2.63e-06 GO:0006397 mRNA processing
1.47 4.03e-06 GO:0016071 mRNA metabolic process
1.31 8.16e-06 GO:0051649 establishment of localization in cell
1.17 9.86e-06 GO:0060255 regulation of macromolecule metabolic process
1.52 1.24e-05 GO:0016032 viral reproduction
1.33 1.33e-05 GO:0032774 RNA biosynthetic process
1.28 2.00e-05 GO:0033036 macromolecule localization
1.49 4.08e-05 GO:0000279 M phase
1.54 4.12e-05 GO:0051301 cell division
1.40 7.74e-05 GO:0009057 macromolecule catabolic process
1.43 1.11e-04 GO:0044265 cellular macromolecule catabolic process
1.09 1.13e-04 GO:0050789 regulation of biological process
1.09 1.22e-04 GO:0050794 regulation of cellular process
1.43 1.46e-04 GO:0006974 response to DNA damage stimulus
1.56 1.63e-04 GO:0008380 RNA splicing
1.52 1.96e-04 GO:0010564 regulation of cell cycle process
1.35 2.64e-04 GO:0016192 vesicle-mediated transport
1.33 2.78e-04 GO:0033554 cellular response to stress
1.50 3.57e-04 GO:0030163 protein catabolic process
1.18 4.66e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.28 5.64e-04 GO:0008104 protein localization
1.74 5.76e-04 GO:0022415 viral reproductive process
1.51 7.38e-04 GO:0070647 protein modification by small protein conjugation or removal
1.65 7.66e-04 GO:0000375 RNA splicing, via transesterification reactions
1.83 8.55e-04 GO:0042254 ribosome biogenesis
1.66 9.50e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.66 9.50e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
1.31 9.94e-04 GO:0015031 protein transport
1.36 9.99e-04 GO:0051726 regulation of cell cycle
1.08 1.08e-03 GO:0065007 biological regulation
1.30 1.09e-03 GO:0045184 establishment of protein localization
2.00 1.17e-03 GO:0000236 mitotic prometaphase
1.60 1.48e-03 GO:0071156 regulation of cell cycle arrest
1.77 1.57e-03 GO:0019058 viral infectious cycle
1.14 1.58e-03 GO:0031323 regulation of cellular metabolic process
1.17 1.63e-03 GO:0010468 regulation of gene expression
1.17 1.97e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.56 2.02e-03 GO:0016567 protein ubiquitination
1.64 2.09e-03 GO:0022613 ribonucleoprotein complex biogenesis
1.25 2.39e-03 GO:0044085 cellular component biogenesis
1.12 2.79e-03 GO:0019222 regulation of metabolic process
1.20 2.81e-03 GO:0006464 protein modification process
1.61 2.89e-03 GO:0071843 cellular component biogenesis at cellular level
1.13 2.92e-03 GO:0080090 regulation of primary metabolic process
1.53 3.12e-03 GO:0010608 posttranscriptional regulation of gene expression
1.85 3.31e-03 GO:0007059 chromosome segregation
1.47 3.80e-03 GO:0044257 cellular protein catabolic process
1.59 3.82e-03 GO:0000075 cell cycle checkpoint
1.87 3.83e-03 GO:0006414 translational elongation
1.52 3.87e-03 GO:0032446 protein modification by small protein conjugation
1.19 4.31e-03 GO:0043412 macromolecule modification
1.46 7.16e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.62 7.16e-03 GO:0022411 cellular component disassembly
1.62 7.16e-03 GO:0071845 cellular component disassembly at cellular level
1.24 7.84e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.25 8.27e-03 GO:0051246 regulation of protein metabolic process
1.80 9.75e-03 GO:0032984 macromolecular complex disassembly
1.80 9.75e-03 GO:0034623 cellular macromolecular complex disassembly
1.25 1.12e-02 GO:0032268 regulation of cellular protein metabolic process
1.46 1.34e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.27 1.45e-02 GO:0006351 transcription, DNA-dependent
1.45 1.65e-02 GO:0019941 modification-dependent protein catabolic process
1.60 1.87e-02 GO:0051169 nuclear transport
1.27 2.27e-02 GO:0008219 cell death
1.60 2.37e-02 GO:0006913 nucleocytoplasmic transport
1.27 2.43e-02 GO:0016265 death
1.32 2.99e-02 GO:0006259 DNA metabolic process
1.44 3.05e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.35 3.23e-02 GO:0001775 cell activation
1.35 3.35e-02 GO:0034621 cellular macromolecular complex subunit organization
1.15 3.40e-02 GO:0048522 positive regulation of cellular process
1.14 3.68e-02 GO:0048518 positive regulation of biological process
1.14 4.46e-02 GO:0009889 regulation of biosynthetic process
1.60 4.71e-02 GO:0006417 regulation of translation
1.14 4.91e-02 GO:0031326 regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 1.26e-43 GO:0044424 intracellular part
1.13 2.26e-42 GO:0005622 intracellular
1.18 4.68e-41 GO:0043227 membrane-bounded organelle
1.18 6.34e-41 GO:0043231 intracellular membrane-bounded organelle
1.16 1.79e-39 GO:0043229 intracellular organelle
1.16 3.11e-39 GO:0043226 organelle
1.24 6.44e-31 GO:0005634 nucleus
1.21 4.53e-24 GO:0044446 intracellular organelle part
1.21 9.80e-24 GO:0044422 organelle part
1.36 1.09e-22 GO:0031974 membrane-enclosed lumen
1.37 6.47e-22 GO:0044428 nuclear part
1.35 1.74e-21 GO:0043233 organelle lumen
1.14 4.30e-20 GO:0005737 cytoplasm
1.34 1.11e-19 GO:0070013 intracellular organelle lumen
1.37 2.03e-18 GO:0031981 nuclear lumen
1.16 3.09e-16 GO:0044444 cytoplasmic part
1.23 3.26e-15 GO:0032991 macromolecular complex
1.30 6.59e-14 GO:0005829 cytosol
1.61 2.49e-12 GO:0030529 ribonucleoprotein complex
1.24 1.31e-11 GO:0043228 non-membrane-bounded organelle
1.24 1.31e-11 GO:0043232 intracellular non-membrane-bounded organelle
1.35 5.27e-11 GO:0005654 nucleoplasm
1.04 6.38e-11 GO:0044464 cell part
1.04 7.01e-11 GO:0005623 cell
1.19 1.43e-07 GO:0043234 protein complex
1.48 6.56e-07 GO:0005730 nucleolus
1.45 1.02e-06 GO:0005694 chromosome
1.89 1.66e-06 GO:0000793 condensed chromosome
1.46 8.91e-06 GO:0044427 chromosomal part
1.80 3.67e-05 GO:0000775 chromosome, centromeric region
2.03 1.90e-04 GO:0000779 condensed chromosome, centromeric region
1.95 2.58e-04 GO:0000776 kinetochore
2.02 6.58e-04 GO:0000777 condensed chromosome kinetochore
1.30 1.41e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.29 2.04e-03 GO:0031988 membrane-bounded vesicle
1.29 2.19e-03 GO:0044451 nucleoplasm part
1.64 3.25e-03 GO:0044445 cytosolic part
1.28 4.38e-03 GO:0031410 cytoplasmic vesicle
1.68 4.55e-03 GO:0005681 spliceosomal complex
1.53 4.80e-03 GO:0000228 nuclear chromosome
1.57 4.83e-03 GO:0005840 ribosome
1.57 6.09e-03 GO:0005819 spindle
1.95 9.18e-03 GO:0030117 membrane coat
1.95 9.18e-03 GO:0048475 coated membrane
1.89 9.40e-03 GO:0022626 cytosolic ribosome
1.63 1.08e-02 GO:0000151 ubiquitin ligase complex
1.15 1.44e-02 GO:0031090 organelle membrane
1.56 1.53e-02 GO:0044454 nuclear chromosome part
1.25 1.93e-02 GO:0031982 vesicle
1.82 2.22e-02 GO:0071013 catalytic step 2 spliceosome
1.46 3.70e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.24e-22 GO:0005515 protein binding
1.53 4.69e-15 GO:0003723 RNA binding
1.08 6.71e-14 GO:0005488 binding
1.21 7.73e-12 GO:0003676 nucleic acid binding
1.19 2.14e-05 GO:0000166 nucleotide binding
1.44 6.98e-04 GO:0000988 protein binding transcription factor activity
1.44 6.98e-04 GO:0000989 transcription factor binding transcription factor activity
1.44 1.02e-03 GO:0003712 transcription cofactor activity
1.69 1.83e-03 GO:0003735 structural constituent of ribosome
1.91 3.79e-03 GO:0008135 translation factor activity, nucleic acid binding
1.92 1.09e-02 GO:0047485 protein N-terminus binding
1.51 1.25e-02 GO:0003713 transcription coactivator activity
1.15 4.10e-02 GO:0017076 purine nucleotide binding
1.69 4.98e-02 GO:0008026 ATP-dependent helicase activity
1.69 4.98e-02 GO:0070035 purine NTP-dependent helicase activity