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• Mean activities

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• Activity deltas table
• Regulatory interactions
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Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 2.871

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_21361901	5.034		MKRN3	makorin ring finger protein 3
chr10_-_11976704	3.407		LOC219731	hypothetical LOC219731
chr12_-_53153613	3.291		GTSF1	gametocyte specific factor 1
chr7_+_50318801	3.150		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr12_-_53153639	3.109	NM_144594	GTSF1	gametocyte specific factor 1
chrX_-_153632355	2.894	NM_001081573 NM_080612	GAB3	GRB2-associated binding protein 3
chrX_-_153428621	2.819		G6PD	glucose-6-phosphate dehydrogenase
chr10_-_43212681	2.777		HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr6_-_168219380	2.767	NM_001122841	FRMD1	FERM domain containing 1
chr2_+_113648036	2.703		PSD4	pleckstrin and Sec7 domain containing 4
chr2_+_169367345	2.636	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr1_+_38046005	2.579		C1orf122	chromosome 1 open reading frame 122
chr1_+_38046055	2.463	NM_001142726 NM_198446	C1orf122	chromosome 1 open reading frame 122
chrX_-_153428968	2.463	NM_001042351	G6PD	glucose-6-phosphate dehydrogenase
chr9_-_122595475	2.438	NM_012164	FBXW2	F-box and WD repeat domain containing 2
chr1_-_38046270	2.422		YRDC	yrdC domain containing (E. coli)
chrX_+_153429022	2.392		IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chrX_-_153908408	2.374		F8	coagulation factor VIII, procoagulant component
chrX_+_153428755	2.363	NM_001099857 NM_001145255	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chrX_+_153908426	2.361		FUNDC2	FUN14 domain containing 2
chrX_+_153429042	2.285		IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr9_-_122595349	2.274		FBXW2	F-box and WD repeat domain containing 2
chrX_-_130792297	2.267		LOC286467	hypothetical LOC286467
chr1_+_20385164	2.264	NM_152376	UBXN10	UBX domain protein 10
chr19_+_17723285	2.246	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr2_+_113648020	2.246	NM_012455	PSD4	pleckstrin and Sec7 domain containing 4
chr1_-_38046433	2.151		YRDC	yrdC domain containing (E. coli)
chr7_+_106292932	2.134		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_120416680	2.080	NM_001105533	C7orf58	chromosome 7 open reading frame 58
chr10_-_43212703	2.071	NM_001098207	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chrX_+_150316351	2.035		VMA21	VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_+_220953278	2.021		BROX	BRO1 domain and CAAX motif containing
chr6_-_31728447	2.019	NM_004639 NM_080702 NM_080703	BAG6	BCL2-associated athanogene 6
chr1_+_38046073	2.003		C1orf122	chromosome 1 open reading frame 122
chr1_-_38046410	2.001		YRDC	yrdC domain containing (E. coli)
chr22_-_19543069	1.988	NM_058004	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr7_+_106293112	1.970	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chrX_+_150316313	1.957	NM_001017980	VMA21	VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chrX_+_153908257	1.939	NM_023934	FUNDC2	FUN14 domain containing 2
chr7_+_106292975	1.939		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr22_+_19191875	1.937		MED15	mediator complex subunit 15
chr9_-_122595413	1.922		FBXW2	F-box and WD repeat domain containing 2
chr16_+_29581783	1.920	NM_001030288	SPN	sialophorin
chr22_+_19191859	1.913		MED15	mediator complex subunit 15
chrX_-_153428196	1.910		G6PD	glucose-6-phosphate dehydrogenase
chr22_-_17798998	1.895		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr22_+_19191886	1.887		MED15	mediator complex subunit 15
chr22_+_19191884	1.886	NM_001003891 NM_015889	MED15	mediator complex subunit 15
chr22_+_19191898	1.885		MED15	mediator complex subunit 15
chr22_-_17799177	1.847		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr22_+_17799341	1.833		MRPL40	mitochondrial ribosomal protein L40
chr7_-_134506001	1.831		C7orf49	chromosome 7 open reading frame 49
chr21_+_45184394	1.818
chrX_-_131179598	1.809	NM_021183	RAP2C	RAP2C, member of RAS oncogene family
chrX_+_150316332	1.801		VMA21	VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_+_38046404	1.800		C1orf122	chromosome 1 open reading frame 122
chr22_+_19543248	1.790	NM_004782	SNAP29	synaptosomal-associated protein, 29kDa
chr7_-_134506012	1.789		C7orf49	chromosome 7 open reading frame 49
chr22_+_19543350	1.780		SNAP29	synaptosomal-associated protein, 29kDa
chr16_+_29582065	1.748		SPN	sialophorin
chr9_-_37775013	1.747		EXOSC3	exosome component 3
chr16_+_29582069	1.736	NM_003123	SPN	sialophorin
chr1_-_51198383	1.712		FAF1	Fas (TNFRSF6) associated factor 1
chr22_-_17799215	1.711	NM_003325	HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr7_-_128482059	1.710		TNPO3	transportin 3
chr1_-_184610796	1.709		TPR	translocated promoter region (to activated MET oncogene)
chr7_-_134505923	1.704		C7orf49	chromosome 7 open reading frame 49
chr1_-_51198417	1.701		FAF1	Fas (TNFRSF6) associated factor 1
chr1_-_164004611	1.677		TMCO1	transmembrane and coiled-coil domains 1
chrX_-_131178977	1.665		RAP2C	RAP2C, member of RAS oncogene family
chr1_-_164004730	1.662	NM_019026	TMCO1	transmembrane and coiled-coil domains 1
chr22_-_18484428	1.662		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr22_-_19543099	1.661		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr2_+_74007439	1.659	NM_080916 NM_080918	DGUOK	deoxyguanosine kinase
chr1_-_40496161	1.631
chr22_+_19191964	1.630		MED15	mediator complex subunit 15
chr2_+_74007495	1.624		DGUOK	deoxyguanosine kinase
chr12_-_70343656	1.618
chr2_-_55131202	1.616	NM_020532 NM_153828 NM_207520	RTN4	reticulon 4
chr1_-_201194040	1.611		ADIPOR1	adiponectin receptor 1
chr17_+_72827185	1.609	NM_006640	SEPT9	septin 9
chr3_-_197549588	1.602		TM4SF19	transmembrane 4 L six family member 19
chr22_-_19543012	1.591		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr1_+_164004789	1.588		LOC100147773	hypothetical LOC100147773
chr6_-_31728405	1.585		BAG6	BCL2-associated athanogene 6
chr1_+_244796441	1.578		CNST	consortin, connexin sorting protein
chr3_-_197549640	1.571	NM_138461	TM4SF19	transmembrane 4 L six family member 19
chr22_+_20350272	1.568	NM_014337 NM_148175 NM_148176	PPIL2	peptidylprolyl isomerase (cyclophilin)-like 2
chr17_+_46585928	1.563		NME1	non-metastatic cells 1, protein (NM23A) expressed in
chr19_+_40431618	1.562		LSR	lipolysis stimulated lipoprotein receptor
chrX_-_119578899	1.560		CUL4B	cullin 4B
chr9_-_37775064	1.550	NM_016042 NM_001002269	EXOSC3	exosome component 3
chr22_+_18485095	1.547		RANBP1	RAN binding protein 1
chr6_-_31728418	1.542		BAG6	BCL2-associated athanogene 6
chr9_-_37775052	1.541		EXOSC3	exosome component 3
chr2_+_74007523	1.537		DGUOK	deoxyguanosine kinase
chr3_+_151747204	1.537	NM_032025	EIF2A	eukaryotic translation initiation factor 2A, 65kDa
chr19_+_40431678	1.534		LSR	lipolysis stimulated lipoprotein receptor
chr1_-_201193892	1.527		ADIPOR1	adiponectin receptor 1
chr6_+_160068531	1.521		WTAP	Wilms tumor 1 associated protein
chr11_+_384238	1.515		PKP3	plakophilin 3
chr17_+_46585895	1.511	NM_000269 NM_198175 NM_001018136	NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr1_-_38046439	1.503	NM_024640	YRDC	yrdC domain containing (E. coli)
chr15_-_62242352	1.502	NM_000942	PPIB	peptidylprolyl isomerase B (cyclophilin B)
chr17_+_24013320	1.501		SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)
chr6_-_28475478	1.497	NM_001163391	ZSCAN12	zinc finger and SCAN domain containing 12
chr9_-_37774785	1.496		EXOSC3	exosome component 3
chr9_-_130124820	1.485		TRUB2	TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr22_-_20235372	1.485	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr9_+_130124873	1.484		COQ4	coenzyme Q4 homolog (S. cerevisiae)
chr3_-_187025501	1.482	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr1_-_184610953	1.477		TPR	translocated promoter region (to activated MET oncogene)
chr21_-_37561463	1.447		DSCR3	Down syndrome critical region gene 3
chr6_-_31728363	1.443		BAG6	BCL2-associated athanogene 6
chr7_-_99355085	1.443	NM_033017 NM_033091	TRIM4	tripartite motif containing 4
chr15_-_72922533	1.436		ULK3	unc-51-like kinase 3 (C. elegans)
chr11_+_60954096	1.435		SDHAF2	succinate dehydrogenase complex assembly factor 2
chr7_-_128482354	1.429		TNPO3	transportin 3
chr6_-_36950520	1.409		PPIL1	peptidylprolyl isomerase (cyclophilin)-like 1
chr21_-_37561495	1.401	NM_006052	DSCR3	Down syndrome critical region gene 3
chr1_+_220953351	1.399		BROX	BRO1 domain and CAAX motif containing
chr2_-_55130963	1.398		RTN4	reticulon 4
chr14_-_37133927	1.381		FOXA1	forkhead box A1
chr6_+_160068553	1.380		WTAP	Wilms tumor 1 associated protein
chr11_-_66925875	1.379		PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme
chr2_+_174968751	1.377		SCRN3	secernin 3
chr6_+_160068544	1.368		WTAP	Wilms tumor 1 associated protein
chr15_-_72922577	1.365	NM_001099436	ULK3	unc-51-like kinase 3 (C. elegans)
chr6_+_31623370	1.360		NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr22_-_17846621	1.359		UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr17_+_72827654	1.357		SEPT9	septin 9
chr17_+_46585953	1.353		NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr14_-_37134050	1.353		FOXA1	forkhead box A1
chr1_+_244796426	1.349		CNST	consortin, connexin sorting protein
chr3_+_151747266	1.348		EIF2A	eukaryotic translation initiation factor 2A, 65kDa
chr6_+_160068598	1.348	NM_152857	WTAP	Wilms tumor 1 associated protein
chr6_+_31741814	1.348		CSNK2B	casein kinase 2, beta polypeptide
chr7_-_91713044	1.345	NM_004912 NM_001013406 NM_194454	KRIT1	KRIT1, ankyrin repeat containing
chr1_-_201194044	1.345		ADIPOR1	adiponectin receptor 1
chr13_-_45654296	1.344		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_33347833	1.340		RPS18	ribosomal protein S18
chr11_+_384199	1.338	NM_007183	PKP3	plakophilin 3
chr21_+_45184324	1.337	NM_058190	C21orf70	chromosome 21 open reading frame 70
chrX_-_153428258	1.336	NM_000402	G6PD	glucose-6-phosphate dehydrogenase
chr1_+_36169260	1.335	NM_024852 NM_177422	EIF2C3	eukaryotic translation initiation factor 2C, 3
chrX_-_40479893	1.331		MED14	mediator complex subunit 14
chr1_-_203867402	1.329		ELK4	ELK4, ETS-domain protein (SRF accessory protein 1)
chr8_-_104496444	1.326		SLC25A32	solute carrier family 25, member 32
chr22_+_18484810	1.325	NM_002882	RANBP1	RAN binding protein 1
chr9_-_133141726	1.325	NM_033387	FAM78A	family with sequence similarity 78, member A
chr8_-_104496495	1.322		SLC25A32	solute carrier family 25, member 32
chr3_-_187025438	1.320		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr11_+_60954150	1.318	NM_017841	SDHAF2	succinate dehydrogenase complex assembly factor 2
chrX_+_131179886	1.317
chr11_+_117735530	1.313		UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chr2_+_68855436	1.313	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr16_-_1999760	1.307	NM_178167	ZNF598	zinc finger protein 598
chr3_-_47798372	1.305		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr11_+_117735502	1.303	NM_004788	UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chrX_+_119622012	1.303		MCTS1	malignant T cell amplified sequence 1
chr8_-_68136881	1.300		COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr15_-_72922482	1.297		ULK3	unc-51-like kinase 3 (C. elegans)
chr7_-_99355065	1.293		TRIM4	tripartite motif containing 4
chr20_+_30019465	1.293	NM_001011718	XKR7	XK, Kell blood group complex subunit-related family, member 7
chr2_-_136459507	1.290		DARS	aspartyl-tRNA synthetase
chr22_-_17846711	1.280		UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr11_+_125644232	1.279		FOXRED1	FAD-dependent oxidoreductase domain containing 1
chr2_+_174968701	1.276	NM_001193528 NM_024583	SCRN3	secernin 3
chr1_-_220829704	1.274	NM_005681 NM_139352	TAF1A	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr19_+_7608010	1.273		STXBP2	syntaxin binding protein 2
chr6_+_160068475	1.273		WTAP	Wilms tumor 1 associated protein
chr7_-_107997132	1.273	NM_182529 NM_001130475	THAP5	THAP domain containing 5
chr1_+_108904191	1.269		FAM102B	family with sequence similarity 102, member B
chr6_+_31623331	1.263	NM_001144961 NM_005007	NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr6_-_33347563	1.261	NM_022553	VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr7_-_128482417	1.255	NM_001191028 NM_012470	TNPO3	transportin 3
chr1_-_201194033	1.252		ADIPOR1	adiponectin receptor 1
chr1_-_20860610	1.249	NM_005216	DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr9_-_139043035	1.248	NM_212533	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr2_-_174968595	1.248	NM_004882	CIR1	corepressor interacting with RBPJ, 1
chr1_-_201194083	1.246	NM_015999	ADIPOR1	adiponectin receptor 1
chr5_+_149360503	1.244		HMGXB3	HMG box domain containing 3
chr3_-_151746970	1.243	NM_014445	SERP1	stress-associated endoplasmic reticulum protein 1
chr9_+_130124566	1.229	NM_016035	COQ4	coenzyme Q4 homolog (S. cerevisiae)
chr6_-_31728121	1.226	NM_001098534	BAG6	BCL2-associated athanogene 6
chr1_-_165754325	1.223	NM_000734 NM_198053	CD247	CD247 molecule
chrX_+_133952633	1.220	NM_001163438	LOC644538	hypothetical protein LOC644538
chr7_-_99355051	1.217		TRIM4	tripartite motif containing 4
chr11_+_117735529	1.217		UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chr1_+_40278958	1.215		CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_36950729	1.214		PPIL1	peptidylprolyl isomerase (cyclophilin)-like 1
chr5_-_40871040	1.212		RPL37 SNORD72	ribosomal protein L37 small nucleolar RNA, C/D box 72
chr22_+_21852911	1.212		BCR	breakpoint cluster region
chrX_-_119578747	1.211	NM_001079872	CUL4B	cullin 4B
chr3_+_47004457	1.209		NBEAL2	neurobeachin-like 2
chr20_+_60246971	1.208		OSBPL2	oxysterol binding protein-like 2
chr12_-_104153920	1.203	NM_018171	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr6_-_153365532	1.198		MTRF1L	mitochondrial translational release factor 1-like
chr1_+_167604056	1.194		BLZF1	basic leucine zipper nuclear factor 1
chr5_+_149360361	1.190	NM_014983	HMGXB3	HMG box domain containing 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.41	8.83e-45	GO:0044260	cellular macromolecule metabolic process
1.34	5.64e-36	GO:0043170	macromolecule metabolic process
1.53	2.48e-31	GO:0090304	nucleic acid metabolic process
1.46	7.79e-31	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	9.74e-27	GO:0044237	cellular metabolic process
1.54	7.22e-24	GO:0016070	RNA metabolic process
1.50	2.61e-22	GO:0010467	gene expression
1.22	7.52e-22	GO:0044238	primary metabolic process
1.35	1.10e-20	GO:0034641	cellular nitrogen compound metabolic process
1.40	9.65e-20	GO:0044267	cellular protein metabolic process
1.33	1.51e-19	GO:0006807	nitrogen compound metabolic process
1.19	1.64e-19	GO:0008152	metabolic process
1.47	1.65e-17	GO:0009059	macromolecule biosynthetic process
1.79	4.73e-17	GO:0006396	RNA processing
1.47	6.76e-17	GO:0034645	cellular macromolecule biosynthetic process
1.86	1.02e-16	GO:0016071	mRNA metabolic process
2.41	5.06e-16	GO:0000375	RNA splicing, via transesterification reactions
1.34	1.00e-15	GO:0071841	cellular component organization or biogenesis at cellular level
1.29	1.74e-15	GO:0071840	cellular component organization or biogenesis
2.39	2.88e-15	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.39	2.88e-15	GO:0000398	nuclear mRNA splicing, via spliceosome
1.92	3.19e-14	GO:0016032	viral reproduction
2.05	1.47e-13	GO:0008380	RNA splicing
1.92	3.32e-13	GO:0006397	mRNA processing
1.10	7.22e-13	GO:0009987	cellular process
1.77	1.31e-12	GO:0006974	response to DNA damage stimulus
1.29	3.17e-12	GO:0019538	protein metabolic process
1.26	2.96e-11	GO:0016043	cellular component organization
1.30	5.37e-11	GO:0071842	cellular component organization at cellular level
1.56	7.46e-11	GO:0033554	cellular response to stress
1.71	7.87e-11	GO:0044265	cellular macromolecule catabolic process
1.31	8.59e-11	GO:0044249	cellular biosynthetic process
1.54	1.17e-10	GO:0045184	establishment of protein localization
1.65	1.91e-10	GO:0009057	macromolecule catabolic process
2.16	2.42e-10	GO:0022613	ribonucleoprotein complex biogenesis
1.54	2.68e-10	GO:0015031	protein transport
2.10	9.37e-10	GO:0071843	cellular component biogenesis at cellular level
1.46	1.66e-09	GO:0008104	protein localization
1.36	2.13e-09	GO:0006996	organelle organization
1.64	2.14e-09	GO:0000278	mitotic cell cycle
1.28	2.83e-09	GO:0009058	biosynthetic process
1.39	1.85e-08	GO:0033036	macromolecule localization
1.44	3.41e-08	GO:0007049	cell cycle
1.41	3.51e-08	GO:0044248	cellular catabolic process
1.51	4.26e-08	GO:0046907	intracellular transport
1.83	4.81e-08	GO:0051329	interphase of mitotic cell cycle
1.54	7.05e-08	GO:0022403	cell cycle phase
1.82	7.13e-08	GO:0051325	interphase
1.95	1.20e-07	GO:0071156	regulation of cell cycle arrest
1.76	2.12e-07	GO:0006281	DNA repair
1.96	2.13e-07	GO:0000075	cell cycle checkpoint
1.73	2.26e-07	GO:0030163	protein catabolic process
1.77	2.42e-07	GO:0051603	proteolysis involved in cellular protein catabolic process
1.56	4.20e-07	GO:0006259	DNA metabolic process
1.75	4.29e-07	GO:0044257	cellular protein catabolic process
1.84	4.62e-07	GO:0034660	ncRNA metabolic process
1.47	5.18e-07	GO:0022402	cell cycle process
1.77	5.60e-07	GO:0006511	ubiquitin-dependent protein catabolic process
1.29	6.88e-07	GO:0043412	macromolecule modification
1.76	6.99e-07	GO:0043632	modification-dependent macromolecule catabolic process
1.73	8.19e-07	GO:0010564	regulation of cell cycle process
1.75	9.93e-07	GO:0019941	modification-dependent protein catabolic process
2.57	1.82e-06	GO:0006353	transcription termination, DNA-dependent
1.29	2.10e-06	GO:0006464	protein modification process
1.75	2.55e-06	GO:0006412	translation
2.19	2.83e-06	GO:0042254	ribosome biogenesis
1.41	3.23e-06	GO:0032774	RNA biosynthetic process
1.35	5.95e-06	GO:0051641	cellular localization
1.32	6.63e-06	GO:0009056	catabolic process
1.35	1.15e-05	GO:0044085	cellular component biogenesis
1.36	1.70e-05	GO:0051649	establishment of localization in cell
1.41	4.36e-05	GO:0043933	macromolecular complex subunit organization
2.16	5.14e-05	GO:0000084	S phase of mitotic cell cycle
1.54	5.66e-05	GO:0034621	cellular macromolecular complex subunit organization
2.12	1.07e-04	GO:0051320	S phase
1.64	1.19e-04	GO:0070647	protein modification by small protein conjugation or removal
1.72	1.40e-04	GO:0016567	protein ubiquitination
1.71	1.49e-04	GO:0007346	regulation of mitotic cell cycle
1.78	2.42e-04	GO:0033365	protein localization to organelle
1.95	2.98e-04	GO:0000082	G1/S transition of mitotic cell cycle
1.68	3.03e-04	GO:0032446	protein modification by small protein conjugation
2.38	3.04e-04	GO:0006302	double-strand break repair
2.00	4.63e-04	GO:0007093	mitotic cell cycle checkpoint
2.38	4.65e-04	GO:0072594	establishment of protein localization to organelle
1.48	4.92e-04	GO:0070727	cellular macromolecule localization
1.56	5.15e-04	GO:0006886	intracellular protein transport
1.43	7.07e-04	GO:0051726	regulation of cell cycle
1.44	7.74e-04	GO:0071822	protein complex subunit organization
1.77	7.94e-04	GO:0006457	protein folding
1.80	8.89e-04	GO:0006260	DNA replication
1.47	9.71e-04	GO:0034613	cellular protein localization
2.16	1.02e-03	GO:0006364	rRNA processing
2.26	1.13e-03	GO:0006354	transcription elongation, DNA-dependent
1.78	1.28e-03	GO:0034470	ncRNA processing
2.72	1.38e-03	GO:0006369	termination of RNA polymerase II transcription
1.61	1.52e-03	GO:0048285	organelle fission
1.35	1.80e-03	GO:0006351	transcription, DNA-dependent
2.10	2.00e-03	GO:0016072	rRNA metabolic process
2.02	2.12e-03	GO:0000077	DNA damage checkpoint
1.61	2.24e-03	GO:0000280	nuclear division
1.61	2.24e-03	GO:0007067	mitosis
1.98	2.46e-03	GO:0031570	DNA integrity checkpoint
2.20	2.51e-03	GO:0000216	M/G1 transition of mitotic cell cycle
1.16	2.68e-03	GO:0060255	regulation of macromolecule metabolic process
1.69	3.22e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.45	4.18e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.58	4.79e-03	GO:0000087	M phase of mitotic cell cycle
1.79	6.77e-03	GO:0010498	proteasomal protein catabolic process
1.79	6.77e-03	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.52	8.31e-03	GO:0051301	cell division
1.58	8.42e-03	GO:0006366	transcription from RNA polymerase II promoter
2.30	9.49e-03	GO:0006368	transcription elongation from RNA polymerase II promoter
2.07	1.02e-02	GO:0071826	ribonucleoprotein complex subunit organization
1.83	1.05e-02	GO:0006310	DNA recombination
2.09	1.09e-02	GO:2000045	regulation of G1/S transition of mitotic cell cycle
2.23	1.42e-02	GO:0071158	positive regulation of cell cycle arrest
1.76	1.56e-02	GO:0022415	viral reproductive process
2.10	1.75e-02	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.56	1.77e-02	GO:0006283	transcription-coupled nucleotide-excision repair
2.15	1.95e-02	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.17	2.04e-02	GO:0006289	nucleotide-excision repair
1.35	2.20e-02	GO:0065003	macromolecular complex assembly
2.08	2.48e-02	GO:0031575	mitotic cell cycle G1/S transition checkpoint
2.08	2.48e-02	GO:0051443	positive regulation of ubiquitin-protein ligase activity
2.08	2.48e-02	GO:0071779	G1/S transition checkpoint
1.14	2.51e-02	GO:0031323	regulation of cellular metabolic process
1.65	2.66e-02	GO:0006605	protein targeting
1.56	3.05e-02	GO:0010608	posttranscriptional regulation of gene expression
2.03	3.22e-02	GO:0051351	positive regulation of ligase activity
1.26	3.78e-02	GO:0010604	positive regulation of macromolecule metabolic process
2.09	3.99e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.28	4.03e-02	GO:0032268	regulation of cellular protein metabolic process
1.33	4.44e-02	GO:0016192	vesicle-mediated transport
1.69	4.58e-02	GO:0043687	post-translational protein modification
2.02	4.83e-02	GO:0022618	ribonucleoprotein complex assembly
2.02	4.83e-02	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.19	4.90e-02	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.19	4.90e-02	GO:0072395	signal transduction involved in cell cycle checkpoint
2.19	4.90e-02	GO:0072401	signal transduction involved in DNA integrity checkpoint
2.19	4.90e-02	GO:0072404	signal transduction involved in G1/S transition checkpoint
2.19	4.90e-02	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
2.19	4.90e-02	GO:0072422	signal transduction involved in DNA damage checkpoint
2.19	4.90e-02	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.19	4.90e-02	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
1.47	4.90e-02	GO:0016568	chromatin modification

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	2.53e-46	GO:0044424	intracellular part
1.16	6.05e-45	GO:0005622	intracellular
1.22	3.18e-42	GO:0043227	membrane-bounded organelle
1.22	5.78e-42	GO:0043231	intracellular membrane-bounded organelle
1.19	1.61e-39	GO:0043229	intracellular organelle
1.19	5.33e-39	GO:0043226	organelle
1.56	1.66e-36	GO:0044428	nuclear part
1.53	1.14e-34	GO:0031974	membrane-enclosed lumen
1.53	5.67e-34	GO:0070013	intracellular organelle lumen
1.29	1.47e-33	GO:0044446	intracellular organelle part
1.29	6.28e-33	GO:0044422	organelle part
1.51	1.26e-32	GO:0043233	organelle lumen
1.58	2.86e-32	GO:0031981	nuclear lumen
1.27	1.70e-29	GO:0005634	nucleus
1.99	3.64e-23	GO:0030529	ribonucleoprotein complex
1.17	6.39e-23	GO:0005737	cytoplasm
1.58	1.08e-21	GO:0005654	nucleoplasm
1.32	2.54e-21	GO:0032991	macromolecular complex
1.20	7.22e-18	GO:0044444	cytoplasmic part
1.76	3.47e-13	GO:0005730	nucleolus
1.35	5.78e-13	GO:0005829	cytosol
1.29	2.81e-12	GO:0043228	non-membrane-bounded organelle
1.29	2.81e-12	GO:0043232	intracellular non-membrane-bounded organelle
2.40	4.34e-11	GO:0005681	spliceosomal complex
1.24	1.78e-09	GO:0043234	protein complex
2.65	1.09e-08	GO:0071013	catalytic step 2 spliceosome
1.51	2.29e-08	GO:0044451	nucleoplasm part
1.04	2.24e-07	GO:0044464	cell part
1.04	2.40e-07	GO:0005623	cell
1.84	1.21e-06	GO:0016604	nuclear body
2.77	8.34e-05	GO:0015030	Cajal body
1.44	1.88e-04	GO:0005694	chromosome
2.09	7.62e-04	GO:0042470	melanosome
2.09	7.62e-04	GO:0048770	pigment granule
1.85	8.45e-04	GO:0000151	ubiquitin ligase complex
1.44	1.90e-03	GO:0044427	chromosomal part
3.05	2.77e-03	GO:0044452	nucleolar part
1.69	2.92e-03	GO:0005840	ribosome
1.19	4.17e-03	GO:0031090	organelle membrane
2.77	5.05e-03	GO:0030532	small nuclear ribonucleoprotein complex
1.23	9.92e-03	GO:0005739	mitochondrion
1.27	1.41e-02	GO:0005794	Golgi apparatus
1.76	2.87e-02	GO:0016607	nuclear speck
1.57	2.94e-02	GO:0000228	nuclear chromosome
1.70	2.99e-02	GO:0000793	condensed chromosome
1.33	4.99e-02	GO:0044431	Golgi apparatus part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	1.88e-30	GO:0005515	protein binding
1.10	2.19e-16	GO:0005488	binding
1.62	7.65e-15	GO:0003723	RNA binding
1.26	7.41e-13	GO:0003676	nucleic acid binding
1.29	8.23e-10	GO:0000166	nucleotide binding
1.28	5.04e-07	GO:0035639	purine ribonucleoside triphosphate binding
1.28	5.40e-07	GO:0017076	purine nucleotide binding
1.28	9.82e-07	GO:0032553	ribonucleotide binding
1.28	9.82e-07	GO:0032555	purine ribonucleotide binding
1.30	1.80e-06	GO:0030554	adenyl nucleotide binding
1.30	1.86e-06	GO:0032559	adenyl ribonucleotide binding
1.30	2.50e-06	GO:0005524	ATP binding
1.85	1.10e-04	GO:0008168	methyltransferase activity
1.12	1.43e-04	GO:0003824	catalytic activity
1.80	3.90e-04	GO:0016741	transferase activity, transferring one-carbon groups
1.50	2.11e-03	GO:0003712	transcription cofactor activity
1.49	2.44e-03	GO:0000988	protein binding transcription factor activity
1.49	2.44e-03	GO:0000989	transcription factor binding transcription factor activity
1.34	2.66e-03	GO:0016462	pyrophosphatase activity
1.34	3.19e-03	GO:0017111	nucleoside-triphosphatase activity
1.57	3.53e-03	GO:0042623	ATPase activity, coupled
1.33	3.58e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
2.23	3.87e-03	GO:0008094	DNA-dependent ATPase activity
1.44	3.96e-03	GO:0016874	ligase activity
1.33	4.80e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
1.21	4.95e-03	GO:0016740	transferase activity
1.59	8.36e-03	GO:0019787	small conjugating protein ligase activity
1.60	1.18e-02	GO:0004842	ubiquitin-protein ligase activity
2.00	1.81e-02	GO:0008135	translation factor activity, nucleic acid binding
1.41	2.51e-02	GO:0004674	protein serine/threonine kinase activity
1.49	2.90e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.30	3.20e-02	GO:0019899	enzyme binding
1.92	4.05e-02	GO:0008565	protein transporter activity
1.78	4.67e-02	GO:0051082	unfolded protein binding