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Motif ID: ETS1,2.p2

Z-value: 3.964

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_29581783	8.451	NM_001030288	SPN	sialophorin
chr7_+_50318801	7.420		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr10_+_49562866	7.013		WDFY4	WDFY family member 4
chr19_-_10311262	6.712	NM_002162	ICAM3	intercellular adhesion molecule 3
chr3_-_184756101	6.548	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chrX_+_65152004	6.120
chr19_+_17723285	5.893	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr7_-_3049872	5.518	NM_032415	CARD11	caspase recruitment domain family, member 11
chr1_-_31003260	5.514	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr1_-_31003181	5.442		LAPTM5	lysosomal protein transmembrane 5
chr6_-_11490487	5.288	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr2_+_113648020	5.264	NM_012455	PSD4	pleckstrin and Sec7 domain containing 4
chr9_-_129707392	5.106		LOC100131355 ST6GALNAC6	hypothetical protein LOC100131355 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_+_29582065	5.070		SPN	sialophorin
chr16_+_29582069	5.051	NM_003123	SPN	sialophorin
chr3_+_47004457	4.899		NBEAL2	neurobeachin-like 2
chr19_+_16860871	4.846		F2RL3	coagulation factor II (thrombin) receptor-like 3
chr2_+_113648036	4.783		PSD4	pleckstrin and Sec7 domain containing 4
chr19_+_54530546	4.746		CD37	CD37 molecule
chr19_+_16860807	4.716	NM_003950	F2RL3	coagulation factor II (thrombin) receptor-like 3
chr1_+_111217244	4.652	NM_000560	CD53	CD53 molecule
chr9_+_94766379	4.610		FGD3	FYVE, RhoGEF and PH domain containing 3
chr15_+_79376295	4.444	NM_004513	IL16	interleukin 16 (lymphocyte chemoattractant factor)
chr7_-_44985175	4.376		MYO1G	myosin IG
chr1_+_111217314	4.352		CD53	CD53 molecule
chr7_-_44985084	4.298		MYO1G	myosin IG
chr14_+_20319049	4.239	NM_005615	RNASE6	ribonuclease, RNase A family, k6
chr7_-_44985202	4.231	NM_033054	MYO1G	myosin IG
chr13_-_45654327	4.229	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_159306037	4.161		ARHGAP30	Rho GTPase activating protein 30
chr21_-_14840506	4.052	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_159899528	4.016	NM_001002273 NM_001002274 NM_001002275 NM_001190828 NM_004001	FCGR2B FCGR2C	Fc fragment of IgG, low affinity IIb, receptor (CD32) Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr16_-_29664765	3.961	NM_175900	C16orf54	chromosome 16 open reading frame 54
chr11_+_65164767	3.961		SIPA1	signal-induced proliferation-associated 1
chr21_-_45165249	3.919		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr7_+_150065594	3.916		GIMAP5	GTPase, IMAP family member 5
chr13_-_45654296	3.872		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr10_+_26767698	3.841		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr13_-_45654292	3.820		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_54530512	3.786		CD37	CD37 molecule
chr21_-_45165302	3.785	NM_000211	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr16_-_49272617	3.774		SNX20	sorting nexin 20
chr9_+_263025	3.757	NM_001190458 NM_001193536	DOCK8	dedicator of cytokinesis 8
chr10_+_26767657	3.670		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr3_-_180460372	3.659	NM_171829	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr19_+_54530497	3.529		CD37	CD37 molecule
chr19_+_54530485	3.514	NM_001040031 NM_001774	CD37	CD37 molecule
chr12_-_53153613	3.497		GTSF1	gametocyte specific factor 1
chr11_+_66927955	3.493		TBC1D10C	TBC1 domain family, member 10C
chr12_-_53153639	3.488	NM_144594	GTSF1	gametocyte specific factor 1
chr19_+_54530458	3.473		CD37	CD37 molecule
chr16_+_28413421	3.454	NM_018690	APOBR	apolipoprotein B receptor
chr22_+_42908589	3.419	NM_001137606	PARVG	parvin, gamma
chr2_-_242205556	3.358	NM_001164356	THAP4	THAP domain containing 4
chr22_-_35875890	3.358	NM_000878	IL2RB	interleukin 2 receptor, beta
chr22_+_42908548	3.350		PARVG	parvin, gamma
chr1_-_155788775	3.335	NM_001195388 NM_031281	FCRL5	Fc receptor-like 5
chr22_+_35586950	3.304	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr1_-_159306210	3.289		ARHGAP30	Rho GTPase activating protein 30
chr1_-_200395741	3.258	NM_080588	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr1_-_159306273	3.224		ARHGAP30	Rho GTPase activating protein 30
chr12_-_53044495	3.153	NM_020370	GPR84	G protein-coupled receptor 84
chr22_+_42908612	3.130		PARVG	parvin, gamma
chr21_-_45165204	3.116		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr9_-_133141726	3.079	NM_033387	FAM78A	family with sequence similarity 78, member A
chr4_+_2783764	3.073		SH3BP2	SH3-domain binding protein 2
chr3_-_123223658	3.068	NM_175924	ILDR1	immunoglobulin-like domain containing receptor 1
chr4_+_2783743	3.034	NM_001145855	SH3BP2	SH3-domain binding protein 2
chr1_+_6008956	2.994	NM_003636 NM_172130	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr3_-_13032130	2.977
chr16_+_30391460	2.953	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr6_+_37081387	2.945	NM_173558	FGD2	FYVE, RhoGEF and PH domain containing 2
chr1_+_6008999	2.823		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr6_+_31661934	2.794	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr1_-_181826086	2.789		NCF2	neutrophil cytosolic factor 2
chrX_-_130792297	2.779		LOC286467	hypothetical LOC286467
chr22_+_36008465	2.768		CYTH4	cytohesin 4
chr12_-_6615348	2.721	NM_020400	LPAR5	lysophosphatidic acid receptor 5
chr10_-_98021144	2.709	NM_001114094 NM_013314	BLNK	B-cell linker
chr22_+_36008511	2.680		CYTH4	cytohesin 4
chr14_+_105024576	2.680		CRIP1	cysteine-rich protein 1 (intestinal)
chr16_-_65108605	2.659		TK2	thymidine kinase 2, mitochondrial
chr16_+_30391550	2.641		ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr10_-_98470164	2.637	NM_152309	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1
chr17_-_44058612	2.634	NM_024017	HOXB9	homeobox B9
chr16_-_30301634	2.624	NM_052838	SEPT1	septin 1
chr15_-_38387410	2.619	NM_004573	PLCB2	phospholipase C, beta 2
chr19_+_17495109	2.612	NM_001098524 NM_173544	FAM129C	family with sequence similarity 129, member C
chr1_+_26744893	2.587		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_40843530	2.549		ARHGAP27	Rho GTPase activating protein 27
chr7_+_150065376	2.546	NM_018384	GIMAP5	GTPase, IMAP family member 5
chr1_-_158883666	2.505	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr10_+_49563520	2.500	NM_020945	WDFY4	WDFY family member 4
chr1_+_26744929	2.479	NM_001006665	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr3_+_188197029	2.464
chr12_-_56157898	2.438	NM_001080156	ARHGAP9	Rho GTPase activating protein 9
chr22_+_36008369	2.402	NM_013385	CYTH4	cytohesin 4
chr1_-_205161821	2.397	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr15_-_38387164	2.363		PLCB2	phospholipase C, beta 2
chr17_-_35975227	2.363	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr11_+_59979857	2.362	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr10_+_114125955	2.347		ACSL5	acyl-CoA synthetase long-chain family member 5
chr21_+_41663853	2.336		MX2	myxovirus (influenza virus) resistance 2 (mouse)
chr2_+_143603439	2.306		ARHGAP15	Rho GTPase activating protein 15
chr19_-_17377383	2.301	NM_004335	BST2	bone marrow stromal cell antigen 2
chr19_-_56825400	2.299	NM_003830	SIGLEC5	sialic acid binding Ig-like lectin 5
chr19_+_17377502	2.291		LOC100507535	hypothetical LOC100507535
chr7_-_149960218	2.288		GIMAP6	GTPase, IMAP family member 6
chr12_+_6926014	2.286		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr12_-_56422120	2.282	NM_014770	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr15_-_38387357	2.277		PLCB2	phospholipase C, beta 2
chr19_+_47073029	2.267	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr12_+_6925997	2.266	NM_080548	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr22_-_36212160	2.237	NM_001166343 NM_002405	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_+_59820413	2.237	NM_006669	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr1_+_202000906	2.222	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr22_+_22435207	2.213	NM_182520	C22orf15	chromosome 22 open reading frame 15
chr2_+_143603368	2.206	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chr12_-_8271460	2.196	NM_018088	FAM90A1	family with sequence similarity 90, member A1
chr2_+_102401580	2.187	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr3_+_120799411	2.176	NM_015900	PLA1A	phospholipase A1 member A
chr12_+_53178834	2.171	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr12_-_6611075	2.169	NM_001142961	LPAR5	lysophosphatidic acid receptor 5
chr19_-_13074973	2.166	NM_005583	LYL1	lymphoblastic leukemia derived sequence 1
chr14_-_22354457	2.159		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr10_+_114126004	2.152		ACSL5	acyl-CoA synthetase long-chain family member 5
chr15_+_89274413	2.142	NM_001039675	UNC45A	unc-45 homolog A (C. elegans)
chr11_-_66961709	2.139	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr16_+_30391609	2.124
chr7_-_100078270	2.124		TFR2	transferrin receptor 2
chr17_+_18971506	2.097	NM_001129778	GRAPL	GRB2-related adaptor protein-like
chr19_-_4491078	2.089		LRG1	leucine-rich alpha-2-glycoprotein 1
chr1_-_27825178	2.076	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr9_-_138387903	2.062		CARD9	caspase recruitment domain family, member 9
chr17_-_3766708	2.057	NM_002558	P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1
chr6_-_119137923	2.052	NM_001178035	C6orf204	chromosome 6 open reading frame 204
chr11_+_63864263	2.052	NM_032251	CCDC88B	coiled-coil domain containing 88B
chr19_-_61324412	2.031		ZNF787	zinc finger protein 787
chr15_+_72861470	2.028	NM_001127190 NM_004383	CSK	c-src tyrosine kinase
chr9_-_113977285	2.022	NM_022486	SUSD1	sushi domain containing 1
chr2_+_230798687	2.014	NM_001005176 NM_007237	SP140	SP140 nuclear body protein
chr9_+_139292094	2.011	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr1_+_32489426	2.006	NM_005356	LCK	lymphocyte-specific protein tyrosine kinase
chr2_-_175170674	1.995		WIPF1	WAS/WASL interacting protein family, member 1
chr19_-_43800374	1.968	NM_001042600 NM_007181	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr16_+_48857962	1.966		ADCY7	adenylate cyclase 7
chr19_-_4491024	1.963	NM_052972	LRG1	leucine-rich alpha-2-glycoprotein 1
chr2_-_120697148	1.959		TMEM185B	transmembrane protein 185B (pseudogene)
chr7_-_149960612	1.954	NM_024711	GIMAP6	GTPase, IMAP family member 6
chr4_-_38710376	1.944	NM_024943	TMEM156	transmembrane protein 156
chr11_+_65164963	1.920
chr19_-_47328399	1.916	NM_002698	POU2F2	POU class 2 homeobox 2
chr8_-_21827057	1.913	NM_003974	DOK2	docking protein 2, 56kDa
chr11_+_66927976	1.906	NM_198517	TBC1D10C	TBC1 domain family, member 10C
chr12_-_101396459	1.896	NM_001111284	IGF1	insulin-like growth factor 1 (somatomedin C)
chr1_-_27825633	1.890	NM_001042729	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr19_+_41085221	1.888	NM_001007469 NM_014266	HCST	hematopoietic cell signal transducer
chr19_+_10258642	1.871	NM_001039132 NM_001544 NM_022377	ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr14_+_99601498	1.870	NM_016337	EVL	Enah/Vasp-like
chr2_+_68815416	1.869	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr3_-_122862447	1.828	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr1_+_208008517	1.827		TRAF3IP3	TRAF3 interacting protein 3
chr18_+_70318001	1.821		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr19_-_18058632	1.820	NM_005535 NM_153701	IL12RB1	interleukin 12 receptor, beta 1
chr16_+_19329557	1.820	NM_001105248 NM_001105249	TMC5	transmembrane channel-like 5
chr22_-_28992787	1.814	NM_020530	OSM	oncostatin M
chr9_-_122728173	1.814		TRAF1	TNF receptor-associated factor 1
chr7_+_732831	1.807	NM_017802	HEATR2	HEAT repeat containing 2
chr1_-_158815895	1.758	NM_001184879 NM_001184881 NM_001184882 NM_003874	CD84	CD84 molecule
chr12_-_109611277	1.754	NM_032369	HVCN1	hydrogen voltage-gated channel 1
chrX_+_128741578	1.739		SASH3	SAM and SH3 domain containing 3
chr17_-_20311411	1.727	NM_001042685	LGALS9B	lectin, galactoside-binding, soluble, 9B
chr12_+_91620749	1.727	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr3_-_122862391	1.723		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr17_-_5078773	1.710	NM_207103	C17orf87	chromosome 17 open reading frame 87
chr17_-_59451662	1.707	NM_001099786 NM_001099787 NM_001099788 NM_001099789	ICAM2	intercellular adhesion molecule 2
chr14_+_99601517	1.705		EVL	Enah/Vasp-like
chr15_-_38387317	1.704		PLCB2	phospholipase C, beta 2
chr7_+_149779011	1.702		GIMAP8	GTPase, IMAP family member 8
chr12_-_50004102	1.700		BIN2	bridging integrator 2
chr19_-_6432765	1.699	NM_024898	DENND1C	DENN/MADD domain containing 1C
chr5_+_95092384	1.680	NM_014899	RHOBTB3	Rho-related BTB domain containing 3
chr15_-_38387266	1.679		PLCB2	phospholipase C, beta 2
chr2_+_233633279	1.670	NM_001017915 NM_005541	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr7_-_37454933	1.669	NM_014800	ELMO1	engulfment and cell motility 1
chr19_-_61324456	1.657	NM_001002836	ZNF787	zinc finger protein 787
chr5_-_149772469	1.654	NM_001025159 NM_004355 NM_001025158	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_-_32892705	1.652	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chrX_+_128741562	1.652	NM_018990	SASH3	SAM and SH3 domain containing 3
chr1_-_153107084	1.649
chr5_-_149772563	1.649		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr21_+_44597911	1.648	NM_003307	TRPM2	transient receptor potential cation channel, subfamily M, member 2
chr10_+_26767268	1.646	NM_019043	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr9_+_92629525	1.644	NM_001174167	SYK	spleen tyrosine kinase
chr1_+_26517045	1.627		CD52	CD52 molecule
chr16_-_49272741	1.627	NM_001144972 NM_153337 NM_182854	SNX20	sorting nexin 20
chr9_-_138387926	1.623	NM_052813 NM_052814	CARD9	caspase recruitment domain family, member 9
chr6_-_133126278	1.617	NM_078488	VNN2	vanin 2
chr12_+_69148120	1.614
chr18_+_70317548	1.607		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.49	7.69e-10	GO:0002376	immune system process
1.78	4.37e-09	GO:0001775	cell activation
1.56	2.20e-06	GO:0002682	regulation of immune system process
1.69	8.58e-06	GO:0002684	positive regulation of immune system process
1.68	9.29e-06	GO:0050776	regulation of immune response
1.96	2.77e-05	GO:0051249	regulation of lymphocyte activation
1.50	3.41e-05	GO:0006955	immune response
1.89	7.10e-05	GO:0002694	regulation of leukocyte activation
2.05	1.05e-04	GO:0051251	positive regulation of lymphocyte activation
1.87	1.07e-04	GO:0045321	leukocyte activation
2.41	1.75e-04	GO:0050851	antigen receptor-mediated signaling pathway
1.84	1.84e-04	GO:0050865	regulation of cell activation
1.97	2.07e-04	GO:0050867	positive regulation of cell activation
1.86	2.24e-04	GO:0030168	platelet activation
2.30	2.41e-04	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.97	2.65e-04	GO:0002696	positive regulation of leukocyte activation
1.27	3.09e-04	GO:0043412	macromolecule modification
4.34	3.12e-04	GO:0050853	B cell receptor signaling pathway
1.94	3.15e-04	GO:0046649	lymphocyte activation
1.16	4.71e-04	GO:0044260	cellular macromolecule metabolic process
2.27	7.09e-04	GO:0002429	immune response-activating cell surface receptor signaling pathway
2.53	7.30e-04	GO:0042113	B cell activation
1.56	8.97e-04	GO:0007596	blood coagulation
1.56	8.97e-04	GO:0050817	coagulation
1.27	1.26e-03	GO:0006464	protein modification process
1.55	1.31e-03	GO:0007599	hemostasis
1.92	1.31e-03	GO:0002764	immune response-regulating signaling pathway
1.92	2.77e-03	GO:0050863	regulation of T cell activation
1.89	3.29e-03	GO:0002757	immune response-activating signal transduction
1.69	3.35e-03	GO:0050778	positive regulation of immune response
1.21	7.30e-03	GO:0006950	response to stress
1.98	8.62e-03	GO:0050870	positive regulation of T cell activation
1.13	9.85e-03	GO:0043170	macromolecule metabolic process
1.46	1.41e-02	GO:0050878	regulation of body fluid levels
1.67	1.59e-02	GO:0010740	positive regulation of intracellular protein kinase cascade
1.24	1.84e-02	GO:0048583	regulation of response to stimulus
1.44	2.20e-02	GO:0042060	wound healing
2.45	2.24e-02	GO:0050864	regulation of B cell activation
1.56	2.36e-02	GO:0044419	interspecies interaction between organisms
1.09	3.22e-02	GO:0065007	biological regulation
1.36	3.38e-02	GO:0048584	positive regulation of response to stimulus
2.06	4.00e-02	GO:0050670	regulation of lymphocyte proliferation
1.34	4.93e-02	GO:0009611	response to wounding

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.07	6.76e-05	GO:0044424	intracellular part
1.06	1.43e-04	GO:0005622	intracellular
1.07	9.71e-03	GO:0043229	intracellular organelle
1.07	1.32e-02	GO:0043226	organelle
1.77	2.00e-02	GO:0031300	intrinsic to organelle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	3.04e-07	GO:0005515	protein binding
1.06	2.15e-03	GO:0005488	binding
2.80	7.84e-03	GO:0003823	antigen binding
1.36	4.81e-02	GO:0046983	protein dimerization activity