Motif ID: FEV.p2

Z-value: 4.502


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)



Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_122862391 5.778 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_184756101 5.702 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr3_-_122862447 5.685 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_106292975 5.066 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_-_56157898 5.015 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr15_+_79376295 4.965 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr4_+_39874921 4.962 NM_004310
RHOH
ras homolog gene family, member H
chr7_+_106292932 4.937 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_-_175207521 4.661 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr11_+_65164167 4.636 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr5_+_61910318 4.532 NM_181506
LRRC70
leucine rich repeat containing 70
chr17_-_31441390 4.307 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr10_+_49562866 4.257 WDFY4
WDFY family member 4
chr13_+_110653407 4.092 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_-_98021144 4.072 NM_001114094
NM_013314
BLNK

B-cell linker

chr2_+_161701711 3.954 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr21_-_14840506 3.904 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr3_-_46224791 3.833 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr17_-_40843530 3.658 ARHGAP27
Rho GTPase activating protein 27
chr6_-_32268267 3.605 GPSM3
G-protein signaling modulator 3
chr17_-_16816113 3.604 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr1_-_155788775 3.593 NM_001195388
NM_031281
FCRL5

Fc receptor-like 5

chr11_-_72111027 3.551 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr7_+_106293112 3.541 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_-_13032130 3.529


chr19_-_44518465 3.438 GMFG
glia maturation factor, gamma
chr1_-_205161821 3.429 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr3_-_114176401 3.396 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr5_-_88214720 3.365 MEF2C
myocyte enhancer factor 2C
chr2_+_134728299 3.354 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr14_+_20319049 3.351 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr6_-_11490487 3.342 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr1_+_111217244 3.339 NM_000560
CD53
CD53 molecule
chr1_-_205012348 3.290 NM_000572
IL10
interleukin 10
chr19_-_10311262 3.273 NM_002162
ICAM3
intercellular adhesion molecule 3
chr22_-_39189369 3.190 MKL1
megakaryoblastic leukemia (translocation) 1
chr1_+_111217314 3.170 CD53
CD53 molecule
chr4_+_91035025 3.129 NM_007351
MMRN1
multimerin 1
chr13_-_27967215 3.103 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr1_-_111544603 3.063


chr7_-_3049872 3.013 NM_032415
CARD11
caspase recruitment domain family, member 11
chr2_-_225519974 3.004 DOCK10
dedicator of cytokinesis 10
chr1_+_111544469 2.962


chr4_-_10295412 2.937 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr22_+_35586950 2.927 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr10_+_26767657 2.887 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_+_40877053 2.876 NM_032587
CARD6
caspase recruitment domain family, member 6
chr16_-_29664765 2.865 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr6_-_32268615 2.856 GPSM3
G-protein signaling modulator 3
chr19_-_56567602 2.855 NM_005601
NKG7
natural killer cell group 7 sequence
chr11_+_65164767 2.827 SIPA1
signal-induced proliferation-associated 1
chr19_-_6432765 2.817 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr9_-_116190038 2.808 AKNA
AT-hook transcription factor
chr1_+_202000906 2.800 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr19_-_47328399 2.797 NM_002698
POU2F2
POU class 2 homeobox 2
chr10_+_26767698 2.714 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_-_246869181 2.711 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr17_-_35975227 2.707 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr10_+_49563520 2.639 NM_020945
WDFY4
WDFY family member 4
chr1_+_159943385 2.637 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chrX_+_12795111 2.611 NM_016562
TLR7
toll-like receptor 7
chr1_-_181826086 2.582 NCF2
neutrophil cytosolic factor 2
chr3_+_120799411 2.582 NM_015900
PLA1A
phospholipase A1 member A
chr19_-_44518516 2.580 NM_004877
GMFG
glia maturation factor, gamma
chr1_-_159306037 2.556 ARHGAP30
Rho GTPase activating protein 30
chr1_-_181826292 2.544 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr6_-_119137923 2.535 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr11_+_63864263 2.505 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr4_-_101658094 2.497 NM_001159694
NM_016242
EMCN

endomucin

chr16_+_56134037 2.473 GPR114
G protein-coupled receptor 114
chr16_+_56134077 2.467 NM_153837
GPR114
G protein-coupled receptor 114
chr7_-_44985175 2.458 MYO1G
myosin IG
chr9_+_94766379 2.447 FGD3
FYVE, RhoGEF and PH domain containing 3
chr1_-_31003260 2.431 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr22_-_35970230 2.419 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr11_-_110755112 2.418 POU2AF1
POU class 2 associating factor 1
chr16_-_30301357 2.404 SEPT1
septin 1
chr11_-_76059435 2.402 NM_001128922
LRRC32
leucine rich repeat containing 32
chr19_-_51820133 2.402 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr1_+_196874867 2.393 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_-_44985202 2.388 NM_033054
MYO1G
myosin IG
chr18_+_70317802 2.358 NM_001168499
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr22_-_35970133 2.349 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_+_47004457 2.341 NBEAL2
neurobeachin-like 2
chrX_+_128741562 2.327 NM_018990
SASH3
SAM and SH3 domain containing 3
chr7_-_44985084 2.327 MYO1G
myosin IG
chr1_-_158815850 2.321 CD84
CD84 molecule
chr2_+_233633348 2.313 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr16_+_29581783 2.302 NM_001030288
SPN
sialophorin
chr12_-_56422120 2.296 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr2_+_233633279 2.268 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr11_+_1830763 2.247 NM_002339
LSP1
lymphocyte-specific protein 1
chr22_-_16080265 2.247 CECR1
cat eye syndrome chromosome region, candidate 1
chr16_-_49272617 2.238 SNX20
sorting nexin 20
chr22_+_36008511 2.234 CYTH4
cytohesin 4
chr3_+_38055699 2.228 NM_007335
NM_007337
DLEC1

deleted in lung and esophageal cancer 1

chr12_-_56159895 2.222 NM_032496
ARHGAP9
Rho GTPase activating protein 9
chr12_+_12829807 2.216 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr17_+_44642587 2.203 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr1_+_157067729 2.202 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr1_-_158815895 2.201 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr13_-_32658215 2.186 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_-_92615593 2.181 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chrX_+_128741578 2.177 SASH3
SAM and SH3 domain containing 3
chr2_-_242205556 2.171 NM_001164356
THAP4
THAP domain containing 4
chr15_-_78050515 2.169 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr8_-_82557956 2.167 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr19_+_41085221 2.145 NM_001007469
NM_014266
HCST

hematopoietic cell signal transducer

chr12_-_52939584 2.131 NM_001127322
CBX5
chromobox homolog 5
chr22_+_36008369 2.123 NM_013385
CYTH4
cytohesin 4
chr7_-_50103335 2.121 NM_001159878
NM_007009
ZPBP

zona pellucida binding protein

chr22_+_36008465 2.111 CYTH4
cytohesin 4
chr7_+_143683365 2.100 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr9_+_263025 2.097 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr2_-_45648608 2.096 SRBD1
S1 RNA binding domain 1
chr21_-_45165204 2.088 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_-_110755366 2.082 NM_006235
POU2AF1
POU class 2 associating factor 1
chr16_-_30301634 2.080 NM_052838
SEPT1
septin 1
chr12_-_56159631 2.078 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr19_-_1083109 2.076 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr13_-_45654327 2.073 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_44642934 2.042 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr1_-_111544784 2.040 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr1_-_159306210 2.034 ARHGAP30
Rho GTPase activating protein 30
chr17_-_26672757 2.016 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr1_-_159306273 2.013 ARHGAP30
Rho GTPase activating protein 30
chr21_-_45165249 1.994 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_26744929 1.992 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr21_+_25856311 1.981 MIR155HG
MIR155 host gene (non-protein coding)
chr2_+_130703384 1.979


chr19_-_11550576 1.977 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr10_-_6144119 1.968 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr1_+_152566899 1.955 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr13_-_45654296 1.954 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_75259714 1.953 PEAK1
NKF3 kinase family member
chr19_+_16860807 1.938 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr19_+_16860871 1.937 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr16_-_49272741 1.934 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chrX_-_130792297 1.930 LOC286467
hypothetical LOC286467
chr21_-_38792173 1.923 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr1_+_26744893 1.911 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr6_-_154719560 1.907 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr1_+_170077234 1.897 NM_001136127
NM_015569
DNM3

dynamin 3

chr14_-_93512818 1.897 ASB2
ankyrin repeat and SOCS box containing 2
chr16_+_30391609 1.896


chr9_-_129656413 1.891 ENG
endoglin
chr4_+_100957003 1.890 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr1_+_207995999 1.886 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr7_+_150044530 1.880 NM_130759
GIMAP1
GTPase, IMAP family member 1
chr12_-_51887266 1.867 NM_000889
ITGB7
integrin, beta 7
chr1_+_32489426 1.866 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr4_+_2783764 1.860 SH3BP2
SH3-domain binding protein 2
chr5_-_66528330 1.855 NM_005582
CD180
CD180 molecule
chr19_+_14412087 1.845 PKN1
protein kinase N1
chr19_+_17495109 1.840 NM_001098524
NM_173544
FAM129C

family with sequence similarity 129, member C

chr18_-_59137488 1.835 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr8_+_75066117 1.835 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr16_+_30391550 1.833 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr4_+_2783743 1.826 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr2_-_179623030 1.821 NM_173648
CCDC141
coiled-coil domain containing 141
chr17_-_59451662 1.809 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr9_-_129656581 1.803 ENG
endoglin
chr2_+_143603439 1.800 ARHGAP15
Rho GTPase activating protein 15
chr5_-_169657192 1.798 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_+_92188546 1.791 RIN3
Ras and Rab interactor 3
chr16_+_29582065 1.789 SPN
sialophorin
chr16_+_30391460 1.787 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr19_-_15436333 1.783 NM_022904
RASAL3
RAS protein activator like 3
chr17_+_4922478 1.762 ZFP3
zinc finger protein 3 homolog (mouse)
chr7_-_149960612 1.745 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr12_+_6517600 1.744


chr15_-_32398220 1.729 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr13_-_45654292 1.728 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_149842850 1.727 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr2_+_143603368 1.710 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr17_+_4922445 1.691 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr7_+_18501876 1.690 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr12_+_25096472 1.690 NM_006152
LRMP
lymphoid-restricted membrane protein
chr12_-_15005761 1.686 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr16_+_29582069 1.684 NM_003123
SPN
sialophorin
chr1_-_111544820 1.678 DENND2D
DENN/MADD domain containing 2D
chr1_+_196874839 1.677 PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_+_107304344 1.662 NM_017516
RAB39
RAB39, member RAS oncogene family
chr12_-_51887318 1.660 ITGB7
integrin, beta 7
chr2_+_130846263 1.658 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr1_+_153413675 1.653 TRIM46
tripartite motif containing 46
chr5_-_169657312 1.651 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_155834357 1.638 NM_031282
FCRL4
Fc receptor-like 4
chr7_-_143523582 1.635 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr21_-_45165302 1.633 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr9_-_129656778 1.626 ENG
endoglin
chr2_-_136590210 1.617 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr19_+_3129735 1.603 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr22_+_22435207 1.602 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr11_+_59979857 1.590 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr14_-_93512647 1.588 ASB2
ankyrin repeat and SOCS box containing 2
chr19_-_47438583 1.585 GSK3A
glycogen synthase kinase 3 alpha
chr11_+_65026382 1.575


chr22_-_35875890 1.574 NM_000878
IL2RB
interleukin 2 receptor, beta
chr2_-_175170674 1.566 WIPF1
WAS/WASL interacting protein family, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.87 1.55e-17 GO:0001775 cell activation
2.18 4.68e-15 GO:0045321 leukocyte activation
1.22 1.27e-13 GO:0044260 cellular macromolecule metabolic process
1.32 4.60e-12 GO:0090304 nucleic acid metabolic process
1.28 1.92e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.15 4.21e-11 GO:0046649 lymphocyte activation
1.09 5.13e-11 GO:0009987 cellular process
1.18 1.22e-09 GO:0043170 macromolecule metabolic process
1.39 4.92e-09 GO:0002376 immune system process
1.26 2.65e-08 GO:0006950 response to stress
2.67 3.97e-08 GO:0042113 B cell activation
1.18 1.01e-07 GO:0051716 cellular response to stimulus
1.48 1.36e-07 GO:0006955 immune response
1.31 2.77e-07 GO:0006996 organelle organization
1.30 3.11e-07 GO:0016070 RNA metabolic process
1.62 3.64e-07 GO:0002684 positive regulation of immune system process
1.23 6.62e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.95 8.70e-07 GO:0050867 positive regulation of cell activation
1.96 9.01e-07 GO:0002696 positive regulation of leukocyte activation
1.57 1.27e-06 GO:0007599 hemostasis
1.57 1.40e-06 GO:0007596 blood coagulation
1.57 1.40e-06 GO:0050817 coagulation
1.19 1.45e-06 GO:0071840 cellular component organization or biogenesis
1.13 1.88e-06 GO:0044237 cellular metabolic process
2.31 1.98e-06 GO:0030098 lymphocyte differentiation
1.96 2.86e-06 GO:0051251 positive regulation of lymphocyte activation
1.81 3.14e-06 GO:0002694 regulation of leukocyte activation
1.58 3.88e-06 GO:0050776 regulation of immune response
1.54 3.99e-06 GO:0006974 response to DNA damage stimulus
1.46 6.17e-06 GO:0002682 regulation of immune system process
1.27 6.71e-06 GO:0010467 gene expression
1.41 1.24e-05 GO:0022402 cell cycle process
1.50 1.36e-05 GO:0050878 regulation of body fluid levels
1.76 1.39e-05 GO:0050865 regulation of cell activation
1.21 1.99e-05 GO:0071842 cellular component organization at cellular level
2.06 2.18e-05 GO:0002521 leukocyte differentiation
1.18 2.26e-05 GO:0007165 signal transduction
1.35 2.69e-05 GO:0007049 cell cycle
1.30 2.86e-05 GO:0035556 intracellular signal transduction
1.79 2.98e-05 GO:0051249 regulation of lymphocyte activation
1.10 3.01e-05 GO:0050789 regulation of biological process
1.11 3.12e-05 GO:0050794 regulation of cellular process
1.18 3.29e-05 GO:0016043 cellular component organization
1.19 3.49e-05 GO:0034641 cellular nitrogen compound metabolic process
1.76 3.71e-05 GO:0030168 platelet activation
1.38 3.89e-05 GO:0009611 response to wounding
1.10 5.77e-05 GO:0065007 biological regulation
2.70 6.67e-05 GO:0002263 cell activation involved in immune response
2.70 6.67e-05 GO:0002366 leukocyte activation involved in immune response
1.38 9.72e-05 GO:0033554 cellular response to stress
1.26 1.18e-04 GO:0009059 macromolecule biosynthetic process
2.04 1.39e-04 GO:0042110 T cell activation
1.11 1.89e-04 GO:0044238 primary metabolic process
1.26 2.00e-04 GO:0034645 cellular macromolecule biosynthetic process
1.94 2.35e-04 GO:0050870 positive regulation of T cell activation
1.17 2.72e-04 GO:0006807 nitrogen compound metabolic process
1.24 2.79e-04 GO:0048583 regulation of response to stimulus
1.21 3.37e-04 GO:0048519 negative regulation of biological process
1.15 3.97e-04 GO:0023052 signaling
1.44 4.20e-04 GO:0042060 wound healing
1.79 4.92e-04 GO:0002764 immune response-regulating signaling pathway
1.44 5.15e-04 GO:0000278 mitotic cell cycle
1.09 7.63e-04 GO:0008152 metabolic process
1.18 7.94e-04 GO:0048518 positive regulation of biological process
1.21 8.83e-04 GO:0048523 negative regulation of cellular process
1.30 9.24e-04 GO:0051649 establishment of localization in cell
1.78 9.65e-04 GO:0002757 immune response-activating signal transduction
2.07 1.32e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.50 1.81e-03 GO:0016032 viral reproduction
1.27 1.84e-03 GO:0051641 cellular localization
1.39 2.47e-03 GO:0051726 regulation of cell cycle
2.62 2.67e-03 GO:0050871 positive regulation of B cell activation
1.75 3.39e-03 GO:0050863 regulation of T cell activation
1.31 3.51e-03 GO:0032774 RNA biosynthetic process
1.96 3.57e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.35 3.67e-03 GO:0016192 vesicle-mediated transport
1.56 4.04e-03 GO:0048285 organelle fission
1.80 4.14e-03 GO:0002697 regulation of immune effector process
1.43 4.35e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.32 5.27e-03 GO:0006351 transcription, DNA-dependent
1.97 5.32e-03 GO:0050670 regulation of lymphocyte proliferation
1.18 5.50e-03 GO:0048522 positive regulation of cellular process
2.14 5.68e-03 GO:0050671 positive regulation of lymphocyte proliferation
1.39 5.91e-03 GO:0006259 DNA metabolic process
2.24 7.31e-03 GO:0030217 T cell differentiation
1.95 7.40e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.95 7.40e-03 GO:0032944 regulation of mononuclear cell proliferation
2.12 8.47e-03 GO:0032946 positive regulation of mononuclear cell proliferation
1.55 9.59e-03 GO:0050778 positive regulation of immune response
1.33 9.65e-03 GO:0046907 intracellular transport
2.59 1.02e-02 GO:0030888 regulation of B cell proliferation
2.24 1.07e-02 GO:0050864 regulation of B cell activation
1.53 1.20e-02 GO:0000087 M phase of mitotic cell cycle
2.09 1.25e-02 GO:0070665 positive regulation of leukocyte proliferation
1.26 1.47e-02 GO:0044085 cellular component biogenesis
1.09 1.82e-02 GO:0050896 response to stimulus
1.61 1.84e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.17 1.90e-02 GO:0044267 cellular protein metabolic process
1.89 1.90e-02 GO:0070663 regulation of leukocyte proliferation
2.45 2.21e-02 GO:0030183 B cell differentiation
1.34 2.27e-02 GO:0022403 cell cycle phase
2.66 3.00e-02 GO:0002285 lymphocyte activation involved in immune response
1.51 3.58e-02 GO:0000280 nuclear division
1.51 3.58e-02 GO:0007067 mitosis
2.03 3.81e-02 GO:0002699 positive regulation of immune effector process
2.03 3.81e-02 GO:0050852 T cell receptor signaling pathway
1.44 4.45e-02 GO:0007264 small GTPase mediated signal transduction
1.46 4.58e-02 GO:0044419 interspecies interaction between organisms
1.19 4.79e-02 GO:0007166 cell surface receptor linked signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 3.26e-14 GO:0044428 nuclear part
1.37 4.54e-14 GO:0031981 nuclear lumen
1.08 4.00e-13 GO:0005622 intracellular
1.08 2.49e-12 GO:0044424 intracellular part
1.30 1.25e-11 GO:0043233 organelle lumen
1.17 1.55e-11 GO:0005634 nucleus
1.29 3.40e-11 GO:0070013 intracellular organelle lumen
1.29 3.80e-11 GO:0031974 membrane-enclosed lumen
1.40 3.98e-11 GO:0005654 nucleoplasm
1.28 4.52e-09 GO:0005829 cytosol
1.10 7.22e-09 GO:0043227 membrane-bounded organelle
1.10 9.26e-09 GO:0043231 intracellular membrane-bounded organelle
1.14 2.81e-08 GO:0044446 intracellular organelle part
1.09 3.45e-08 GO:0043229 intracellular organelle
1.09 5.05e-08 GO:0043226 organelle
1.22 6.35e-08 GO:0043228 non-membrane-bounded organelle
1.22 6.35e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.14 1.12e-07 GO:0044422 organelle part
1.04 2.86e-07 GO:0044464 cell part
1.04 3.08e-07 GO:0005623 cell
1.09 7.05e-07 GO:0005737 cytoplasm
1.18 1.70e-06 GO:0032991 macromolecular complex
1.19 4.89e-06 GO:0043234 protein complex
1.34 9.58e-04 GO:0044451 nucleoplasm part
1.38 1.93e-03 GO:0005694 chromosome
1.38 5.18e-03 GO:0005730 nucleolus
1.09 6.22e-03 GO:0044444 cytoplasmic part
1.39 8.61e-03 GO:0005768 endosome
1.37 1.69e-02 GO:0044427 chromosomal part
1.19 2.77e-02 GO:0005856 cytoskeleton
1.29 4.31e-02 GO:0015630 microtubule cytoskeleton
2.29 4.83e-02 GO:0000118 histone deacetylase complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 2.62e-18 GO:0005515 protein binding
1.06 3.00e-06 GO:0005488 binding
2.31 7.28e-04 GO:0035591 signaling adaptor activity
2.28 1.16e-02 GO:0005070 SH3/SH2 adaptor activity
1.29 1.32e-02 GO:0003723 RNA binding
1.13 3.09e-02 GO:0003676 nucleic acid binding
2.35 3.35e-02 GO:0003823 antigen binding