Motif ID: FOSL2.p2

Z-value: 1.589


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2



Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_72883128 5.845 NM_001305
CLDN4
claudin 4
chr6_-_31853027 4.362 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr1_-_45045543 3.864 NM_001013632
TCTEX1D4
Tctex1 domain containing 4
chr2_+_119905812 2.612 NM_183240
TMEM37
transmembrane protein 37
chr17_+_72958207 2.560 NM_001113496
SEPT9
septin 9
chr16_+_51690564 2.546 CHD9
chromodomain helicase DNA binding protein 9
chr17_+_7423662 2.402 CD68
CD68 molecule
chr17_+_72958330 2.370 SEPT9
septin 9
chr4_-_977163 2.364 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr6_-_149847718 2.291 ZC3H12D
zinc finger CCCH-type containing 12D
chr17_+_7423685 2.213 CD68
CD68 molecule
chr6_-_149847809 2.202 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr12_+_54910767 2.148 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr7_+_128367961 2.096 NM_001098627
IRF5
interferon regulatory factor 5
chr22_+_43451600 1.934 PRR5
proline rich 5 (renal)
chr17_+_7423704 1.932 CD68
CD68 molecule
chr4_+_6746466 1.927 NM_005980
S100P
S100 calcium binding protein P
chr11_+_2881080 1.918 SLC22A18
solute carrier family 22, member 18
chr2_-_152538694 1.888 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr20_+_42463350 1.871 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_+_42463387 1.706 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_+_42463279 1.688 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr19_+_4180494 1.682 NM_005755
EBI3
Epstein-Barr virus induced 3
chr20_+_42463419 1.679 HNF4A
hepatocyte nuclear factor 4, alpha
chr16_+_68765428 1.638 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr17_-_53764867 1.636


chr17_-_35975227 1.635 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr16_-_11918019 1.570 NM_001130007
GSPT1
G1 to S phase transition 1
chr17_-_40858775 1.559 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr9_+_131291224 1.557 LOC100506190
hypothetical LOC100506190
chrX_+_115481848 1.540 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr22_+_21370394 1.510 IGL@
immunoglobulin lambda locus
chr17_-_30414789 1.494 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr12_+_110689094 1.481 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr16_+_28413421 1.453 NM_018690
APOBR
apolipoprotein B receptor
chr9_+_131291144 1.436


chr1_-_93030538 1.427 NM_005665
EVI5
ecotropic viral integration site 5
chr2_+_27358800 1.395 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr16_-_30032330 1.390 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr20_+_34206070 1.378 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_-_51633042 1.376 NM_006526
ZNF217
zinc finger protein 217
chr1_-_218168404 1.360


chr9_+_4829763 1.356 RCL1
RNA terminal phosphate cyclase-like 1
chr6_-_35804337 1.339 NM_001145775
FKBP5
FK506 binding protein 5
chr1_-_152201814 1.330 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr17_+_7423528 1.319 NM_001251
NM_001040059
CD68

CD68 molecule

chr14_+_87560646 1.297 LOC283587
hypothetical protein LOC283587
chr22_+_20316968 1.278 NM_152612
CCDC116
coiled-coil domain containing 116
chr7_+_26298136 1.269 SNX10
sorting nexin 10
chr17_+_35718948 1.261 NM_000964
RARA
retinoic acid receptor, alpha
chr16_-_1369613 1.253 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr16_+_48857962 1.252 ADCY7
adenylate cyclase 7
chr1_-_27113018 1.249 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr17_-_71287417 1.242 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr16_+_57091546 1.225 NDRG4
NDRG family member 4
chr12_-_47545816 1.221 NM_014470
RND1
Rho family GTPase 1
chr22_-_41672990 1.211 NM_007229
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr10_-_95350949 1.197 NM_006744
RBP4
retinol binding protein 4, plasma
chr16_+_65870641 1.186 PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr3_-_121883647 1.184 HGD
homogentisate 1,2-dioxygenase
chr17_-_70480385 1.184 NM_030630
C17orf28
chromosome 17 open reading frame 28
chr14_-_23847000 1.175 CIDEB
cell death-inducing DFFA-like effector b
chr3_-_197549640 1.173 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr2_-_241484245 1.173 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr12_+_119900677 1.168 HNF1A
HNF1 homeobox A
chr17_-_77868659 1.166 NM_006137
CD7
CD7 molecule
chr8_+_11599119 1.165 NM_002052
GATA4
GATA binding protein 4
chrX_+_115481774 1.165 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr6_+_131190237 1.155 NM_001195597
LOC285733
hypothetical LOC285733
chr1_-_156923111 1.146 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr12_+_54361596 1.132 NM_152637
METTL7B
methyltransferase like 7B
chr19_+_40895669 1.130 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr10_-_101831579 1.118 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr7_+_30927439 1.107 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr16_+_2023279 1.103 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr3_-_122862391 1.100 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_26070330 1.094 NM_178422
PAQR7
progestin and adipoQ receptor family member VII
chr11_-_107874128 1.090 NM_153705
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr3_-_180460372 1.088 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_-_122862447 1.086 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr14_-_23847024 1.086 CIDEB
cell death-inducing DFFA-like effector b
chr5_-_138746917 1.084 NM_005847
NM_152685
SLC23A1

solute carrier family 23 (nucleobase transporters), member 1

chr7_+_101704145 1.081 CUX1
cut-like homeobox 1
chr11_-_64906683 1.079 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr14_-_23846904 1.075 CIDEB
cell death-inducing DFFA-like effector b
chr16_+_88515917 1.070 NM_001197181
TUBB3
tubulin, beta 3
chr15_+_57691382 1.068 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr16_+_65870481 1.063 NM_001129728
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr22_+_49272078 1.063 NM_017584
MIOX
myo-inositol oxygenase
chr14_-_23846993 1.059 CIDEB
cell death-inducing DFFA-like effector b
chr16_+_65869558 1.047 NM_001129727
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr17_+_71292275 1.038 NM_001080419
UNK
unkempt homolog (Drosophila)
chr20_+_31059174 1.028 BPIL1
bactericidal/permeability-increasing protein-like 1
chr10_+_134751398 1.027 NM_001083909
GPR123
G protein-coupled receptor 123
chr20_-_43889339 1.026 NM_003279
TNNC2
troponin C type 2 (fast)
chrX_-_24600661 1.025 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr19_-_40696393 1.018 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr14_-_22658078 1.017 NM_001805
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr2_+_97696462 1.016 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr16_+_84204424 1.016 NM_014615
KIAA0182
KIAA0182
chr15_+_86983038 1.013 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_+_54361685 1.007 METTL7B
methyltransferase like 7B
chr15_+_73803351 1.006 NM_175881
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr9_-_33392505 0.995 NM_001170
AQP7
aquaporin 7
chr3_+_142569988 0.990 ZBTB38
zinc finger and BTB domain containing 38
chr13_+_96592051 0.989 MBNL2
muscleblind-like 2 (Drosophila)
chr3_-_8668723 0.982 NM_015931
C3orf32
chromosome 3 open reading frame 32
chr19_-_18246166 0.969 NM_001145304
NM_001145305
NM_025249
KIAA1683


KIAA1683


chr22_+_20899155 0.966


chr12_-_51629874 0.959 KRT8
keratin 8
chr11_+_74548472 0.935 NM_001145211
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr9_-_33392583 0.929 AQP7
aquaporin 7
chr1_-_218168548 0.925 NM_018713
SLC30A10
solute carrier family 30, member 10
chr3_+_120984246 0.923 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr3_-_121884091 0.922 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr19_-_56564068 0.908 NM_152353
CLDND2
claudin domain containing 2
chr9_-_139068269 0.903 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr13_-_40666392 0.898 KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr5_-_138746840 0.897 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr20_+_41621119 0.896 SGK2
serum/glucocorticoid regulated kinase 2
chr15_+_57691272 0.894 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_-_118571793 0.890 NM_001145018
CCDC153
coiled-coil domain containing 153
chr9_-_122728173 0.879 TRAF1
TNF receptor-associated factor 1
chr14_+_104218487 0.878


chr10_-_31328426 0.877 NM_001143769
ZNF438
zinc finger protein 438
chr3_-_197549588 0.874 TM4SF19
transmembrane 4 L six family member 19
chr16_+_30876115 0.870 NM_014712
SETD1A
SET domain containing 1A
chr12_+_50731457 0.868 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr11_-_786175 0.858 NM_024698
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr5_-_169657360 0.856 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr8_-_27528105 0.846 CLU
clusterin
chr19_-_40939756 0.837 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr7_+_149696263 0.836 REPIN1
replication initiator 1
chr9_-_33392463 0.836 AQP7
aquaporin 7
chr2_+_96354754 0.835 NM_001008949
NM_001163523
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr1_-_154941861 0.826 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr19_+_1223475 0.823 CIRBP
cold inducible RNA binding protein
chr8_+_22266256 0.819 PIWIL2
piwi-like 2 (Drosophila)
chr11_-_2118743 0.816 IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_197427779 0.814 NM_152672
OSTalpha
organic solute transporter alpha
chr12_+_119900931 0.810 NM_000545
HNF1A
HNF1 homeobox A
chr6_+_32229278 0.810 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr1_+_153232685 0.800 NM_018655
LENEP
lens epithelial protein
chr5_-_135259403 0.796 NM_000590
IL9
interleukin 9
chr8_+_82807218 0.795 NM_152284
CHMP4C
chromatin modifying protein 4C
chr17_-_31231421 0.792 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr1_-_108032645 0.791 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr1_+_173111306 0.790 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr4_+_661710 0.789 NM_002477
MYL5
myosin, light chain 5, regulatory
chr6_+_14032655 0.787 NM_001165034
RNF182
ring finger protein 182
chr14_-_37134191 0.786 NM_004496
FOXA1
forkhead box A1
chr6_-_30793436 0.783 NM_014641
MDC1
mediator of DNA-damage checkpoint 1
chr19_+_55398680 0.782 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chrX_-_154216929 0.780 NM_001289
CLIC2
chloride intracellular channel 2
chr6_+_64289585 0.772 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_-_43523825 0.771 NM_182517
NM_001164829
C1orf210

chromosome 1 open reading frame 210

chr19_-_53935648 0.768 NM_017805
RASIP1
Ras interacting protein 1
chr5_-_169657312 0.758 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr10_+_70745615 0.753 NM_033496
HK1
hexokinase 1
chr22_+_21393107 0.751 IGLJ3
immunoglobulin lambda joining 3
chr22_+_36549334 0.751 NM_003614
GALR3
galanin receptor 3
chr11_+_10433241 0.751 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr19_-_53832381 0.743 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr13_-_40666533 0.742 NM_032138
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr6_+_25760352 0.738 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr6_-_32121784 0.735 NM_032470
TNXB
tenascin XB
chr6_+_33151703 0.733 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr19_+_40431359 0.733 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr11_+_72660894 0.732 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr19_-_411995 0.731 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr22_-_48437081 0.729 C22orf34
chromosome 22 open reading frame 34
chr17_-_53950191 0.722 NM_004687
MTMR4
myotubularin related protein 4
chr14_-_93924663 0.721 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_74458897 0.714 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr11_+_384199 0.711 NM_007183
PKP3
plakophilin 3
chrX_-_76824726 0.709 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr17_+_7402315 0.700 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr3_-_9895633 0.697 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr6_+_32003380 0.688 C2
complement component 2
chr3_+_38363292 0.683 XYLB
xylulokinase homolog (H. influenzae)
chr12_+_111900650 0.679 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr6_-_30792830 0.677 MDC1
mediator of DNA-damage checkpoint 1
chr3_+_38363299 0.669 XYLB
xylulokinase homolog (H. influenzae)
chr17_+_22823151 0.666 NM_014238
KSR1
kinase suppressor of ras 1
chr16_-_31068882 0.665 NM_173502
PRSS36
protease, serine, 36
chr11_+_384238 0.661 PKP3
plakophilin 3
chr14_-_34661156 0.659 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr22_-_37044034 0.652 NM_001894
CSNK1E
casein kinase 1, epsilon
chr7_+_1092968 0.649 NM_001039966
NM_001505
GPER

G protein-coupled estrogen receptor 1

chr2_+_169631777 0.645 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chrX_+_30143595 0.641 NM_002364
MAGEB2
melanoma antigen family B, 2
chr7_-_51351825 0.638 COBL
cordon-bleu homolog (mouse)
chr16_-_87570716 0.636 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr20_+_31059038 0.628 NM_025227
BPIL1
bactericidal/permeability-increasing protein-like 1
chr2_+_169367345 0.627 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr17_+_75319476 0.626 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr4_+_76700281 0.622 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr14_+_68796621 0.618 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr6_-_36518643 0.617 NM_152990
PXT1
peroxisomal, testis specific 1
chr6_+_32229599 0.613 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 9.78e-04 GO:0010033 response to organic substance
2.67 8.91e-03 GO:0032496 response to lipopolysaccharide

Nothing significant found in compartment category.

Nothing significant found in function category.