Motif ID: FOXA2.p3

Z-value: 2.586


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2



Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_131190237 6.829 NM_001195597
LOC285733
hypothetical LOC285733
chr17_+_69939130 6.455 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr4_+_69716298 6.403 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr3_-_150422474 5.863 NM_000096
CP
ceruloplasmin (ferroxidase)
chr4_+_6746466 5.390 NM_005980
S100P
S100 calcium binding protein P
chr3_-_71376919 5.318 FOXP1
forkhead box P1
chr17_+_50699965 5.310 HLF
hepatic leukemia factor
chr2_+_113601616 5.277 IL1RN
interleukin 1 receptor antagonist
chr12_+_119900931 5.257 NM_000545
HNF1A
HNF1 homeobox A
chr5_+_132237253 4.969 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr22_+_19458378 4.863 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_+_113601608 4.848 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr6_-_41823056 4.742 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr1_-_167822248 4.591 F5
coagulation factor V (proaccelerin, labile factor)
chr1_-_167822334 4.572 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr12_+_119900677 4.559 HNF1A
HNF1 homeobox A
chr1_-_176205672 4.488 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr16_-_86527608 4.341 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr2_-_233586164 4.291 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr1_-_229627412 4.178 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr5_+_147754467 4.158 FBXO38
F-box protein 38
chr2_-_233586145 4.067 NGEF
neuronal guanine nucleotide exchange factor
chr1_-_57204208 4.055 NM_000066
C8B
complement component 8, beta polypeptide
chr12_-_51629874 3.724 KRT8
keratin 8
chr15_+_64661560 3.676


chr14_-_37134050 3.620 FOXA1
forkhead box A1
chr14_-_93859394 3.531 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr6_+_32003180 3.444 NM_000063
NM_001145903
C2

complement component 2

chr5_+_27508139 3.419 LOC643401
hypothetical protein LOC643401
chr17_-_23721430 3.399 VTN
vitronectin
chr17_+_64922420 3.330 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_16203317 3.303 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr4_+_39084936 3.282 KLB
klotho beta
chr7_+_116238309 3.281 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr6_-_31953425 3.267 NM_001178045
SLC44A4
solute carrier family 44, member 4
chr17_-_23721351 3.254 VTN
vitronectin
chr12_-_9159707 3.218 A2M
alpha-2-macroglobulin
chr17_-_61655915 3.208 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_165133239 3.202 GRB14
growth factor receptor-bound protein 14
chr12_-_9159742 3.163 A2M
alpha-2-macroglobulin
chr17_-_43390108 3.116 NM_024320
PRR15L
proline rich 15-like
chr12_-_9159780 3.065 A2M
alpha-2-macroglobulin
chr10_+_101532544 3.045 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr3_-_121883647 2.952 HGD
homogentisate 1,2-dioxygenase
chr14_-_22358752 2.947 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr10_+_102722275 2.920 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr6_+_112481970 2.912 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr14_+_87560646 2.897 LOC283587
hypothetical protein LOC283587
chrX_-_55037235 2.893 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr22_+_33792125 2.880 NM_001008494
ISX
intestine-specific homeobox
chr1_-_177106702 2.876 NM_004673
ANGPTL1
angiopoietin-like 1
chr3_+_187813553 2.847 AHSG
alpha-2-HS-glycoprotein
chr17_-_6958695 2.825 ASGR2
asialoglycoprotein receptor 2
chr4_+_39084867 2.819 NM_175737
KLB
klotho beta
chr11_-_34491878 2.812 NM_001422
ELF5
E74-like factor 5 (ets domain transcription factor)
chr12_+_99391681 2.803 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_+_99391870 2.800 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_-_176205970 2.794 SEC16B
SEC16 homolog B (S. cerevisiae)
chr3_-_121884091 2.762 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr20_+_31334601 2.740 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr17_-_23721420 2.732 VTN
vitronectin
chr11_-_116168316 2.707 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr12_+_27740694 2.702 NM_001029874
REP15
RAB15 effector protein
chr18_+_27425727 2.691 NM_000371
TTR
transthyretin
chr17_-_23721468 2.670 VTN
vitronectin
chr10_-_54201400 2.668 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr3_+_152970904 2.619 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr1_-_1346465 2.544 NM_001145210
LOC441869
hypothetical protein LOC441869
chr8_-_30121741 2.517 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr11_-_117640078 2.499


chr5_-_42847716 2.479 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr22_-_37044034 2.401 NM_001894
CSNK1E
casein kinase 1, epsilon
chr4_-_186969202 2.394 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr9_-_14900992 2.390 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr12_-_101835026 2.380 PAH
phenylalanine hydroxylase
chr7_+_94953148 2.348 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr17_-_23721485 2.334 NM_000638
VTN
vitronectin
chr10_+_7785347 2.328 ITIH2
inter-alpha (globulin) inhibitor H2
chr6_-_26038817 2.318 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr4_+_187424336 2.318 F11
coagulation factor XI
chr11_+_22652894 2.315 NM_005256
GAS2
growth arrest-specific 2
chr10_+_7785235 2.296 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785360 2.284 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785290 2.217 ITIH2
inter-alpha (globulin) inhibitor H2
chr18_-_50777634 2.195 NM_025214
CCDC68
coiled-coil domain containing 68
chr20_-_52120421 2.188 BCAS1
breast carcinoma amplified sequence 1
chr3_+_187813538 2.187 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr9_+_135276940 2.171 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr10_+_101532450 2.166 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr10_+_7785331 2.119 ITIH2
inter-alpha (globulin) inhibitor H2
chr1_-_205272619 2.114 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr1_+_148496792 2.111 NM_012113
CA14
carbonic anhydrase XIV
chr7_+_134226727 2.062 CALD1
caldesmon 1
chr9_+_135277264 2.060 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr11_+_22652957 2.050 GAS2
growth arrest-specific 2
chr3_+_173043832 2.010 NM_001164436
TMEM212
transmembrane protein 212
chr3_-_49434874 2.005 AMT
aminomethyltransferase
chr17_+_9686572 1.974 GLP2R
glucagon-like peptide 2 receptor
chr21_-_42608531 1.973 TFF3
trefoil factor 3 (intestinal)
chr4_-_40211324 1.935 RBM47
RNA binding motif protein 47
chr4_+_187385618 1.909 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr14_+_20226762 1.906 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr20_+_41621079 1.876 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr12_-_9159789 1.855 NM_000014
A2M
alpha-2-macroglobulin
chr17_+_38259620 1.830 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr1_-_109651140 1.830 NM_001010985
MYBPHL
myosin binding protein H-like
chr9_-_115880494 1.829 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr10_-_69267774 1.825 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr1_-_150070849 1.824 NM_005060
RORC
RAR-related orphan receptor C
chrX_-_15198093 1.820 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr7_-_50596238 1.804 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr2_-_21120314 1.791 APOB
apolipoprotein B (including Ag(x) antigen)
chr5_+_175908948 1.790 NM_017675
CDHR2
cadherin-related family member 2
chr14_-_20563698 1.777 NDRG2
NDRG family member 2
chr5_+_59819761 1.772 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr5_+_145296313 1.761 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr1_+_26376611 1.757 CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr17_-_36418869 1.750 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr19_-_63715135 1.749 NM_012254
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr1_-_20682541 1.722


chr2_-_32344192 1.710 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr14_-_20563722 1.693 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr1_-_159459999 1.692 NM_001643
APOA2
apolipoprotein A-II
chr10_+_89257569 1.684 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr1_+_40486159 1.683 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr1_+_54132447 1.667 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr4_+_187424111 1.659 NM_000128
F11
coagulation factor XI
chrX_+_49718954 1.657 NM_000084
CLCN5
chloride channel 5
chr14_-_106282128 1.655 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_-_6958773 1.650 NM_001181
NM_080912
NM_080913
ASGR2


asialoglycoprotein receptor 2


chr20_-_49612574 1.634 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr3_+_187813405 1.624 AHSG
alpha-2-HS-glycoprotein
chr2_-_135498716 1.621 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr9_+_139245197 1.620 NM_080877
SLC34A3
solute carrier family 34 (sodium phosphate), member 3
chr14_+_38772870 1.620 NM_054024
MIA2
melanoma inhibitory activity 2
chr7_+_113842470 1.618 FOXP2
forkhead box P2
chr11_-_6418705 1.611 NM_000613
HPX
hemopexin
chr11_+_62893836 1.599 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr8_+_18072250 1.598 NM_001160179
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr6_+_64414389 1.593 NM_015153
PHF3
PHD finger protein 3
chr8_+_21967008 1.580 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr10_-_44794146 1.574 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr1_-_57057956 1.568 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr14_+_20493467 1.545 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr9_+_139245029 1.529 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr5_-_59819642 1.521 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_-_31332568 1.508 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr22_-_35835548 1.501 TMPRSS6
transmembrane protease, serine 6
chr9_-_116305273 1.499 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr2_+_11591692 1.495 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr3_-_12175646 1.488 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr10_+_24795446 1.467 KIAA1217
KIAA1217
chr1_+_15351585 1.453 NM_001136216
NM_001136217
TMEM51

transmembrane protein 51

chr12_-_119249938 1.452 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr10_+_24795465 1.442 KIAA1217
KIAA1217
chr9_+_123088690 1.439 GSN
gelsolin
chr20_-_52120710 1.427 NM_003657
BCAS1
breast carcinoma amplified sequence 1
chr3_+_112934016 1.419 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr1_+_74473672 1.416 NM_015978
TNNI3K
TNNI3 interacting kinase
chr11_+_62813947 1.403 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr2_-_152538694 1.398 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr22_-_25205376 1.383 NM_152841
HPS4
Hermansky-Pudlak syndrome 4
chr7_+_99263571 1.380 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr2_-_21084077 1.376 APOB
apolipoprotein B (including Ag(x) antigen)
chrX_-_131375217 1.374 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr9_+_34643911 1.363 NM_004512
NM_147162
IL11RA

interleukin 11 receptor, alpha

chr20_-_49612745 1.361 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr8_-_142307854 1.358 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr2_+_214984705 1.356 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr13_+_49658016 1.338


chr1_-_20179495 1.321 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr3_-_25658829 1.302 TOP2B
topoisomerase (DNA) II beta 180kDa
chr4_-_100070808 1.297 NM_001130679
NM_001968
EIF4E

eukaryotic translation initiation factor 4E

chr3_+_195336631 1.283 HES1
hairy and enhancer of split 1, (Drosophila)
chr5_-_142046175 1.279 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr2_-_20390601 1.272 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr1_+_15351885 1.272 TMEM51
transmembrane protein 51
chr17_+_7423704 1.248 CD68
CD68 molecule
chr4_+_74496575 1.237 ALB
albumin
chr20_-_48741481 1.237


chr14_+_104337923 1.223 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr2_-_21120398 1.222 APOB
apolipoprotein B (including Ag(x) antigen)
chr20_+_31613800 1.206 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr11_+_22646229 1.202 NM_177553
GAS2
growth arrest-specific 2
chr14_-_69333624 1.193 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr2_-_21081694 1.193 APOB
apolipoprotein B (including Ag(x) antigen)
chr17_+_7423662 1.188 CD68
CD68 molecule
chr2_-_21084911 1.187 APOB
apolipoprotein B (including Ag(x) antigen)
chr17_+_7423685 1.184 CD68
CD68 molecule
chr2_-_21120420 1.171 NM_000384
APOB
apolipoprotein B (including Ag(x) antigen)
chr17_-_36938025 1.171 KRT19
keratin 19
chr2_-_192420168 1.164 NM_004657
SDPR
serum deprivation response
chr12_-_69838045 1.159 NM_004616
TSPAN8
tetraspanin 8
chr6_+_26359805 1.148 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr7_+_134483305 1.143 NM_018295
TMEM140
transmembrane protein 140
chr17_-_46296376 1.134 NM_005749
TOB1
transducer of ERBB2, 1
chr7_+_116151411 1.133 MET
met proto-oncogene (hepatocyte growth factor receptor)
chr16_-_4778317 1.130 NM_001154458
NM_144605
SEPT12

septin 12

chr11_+_70954256 1.129 NM_001012710
KRTAP5-10
keratin associated protein 5-10
chr6_+_31731647 1.122 NM_019101
APOM
apolipoprotein M

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.46 1.29e-04 GO:0005576 extracellular region
1.58 4.39e-03 GO:0044421 extracellular region part
1.60 2.36e-02 GO:0005615 extracellular space

Nothing significant found in function category.