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Motif ID: FOXP3.p2

Z-value: 1.942

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_-_100527799	6.958	NM_000061	BTK	Bruton agammaglobulinemia tyrosine kinase
chr4_+_39874921	4.807	NM_004310	RHOH	ras homolog gene family, member H
chr9_-_70780574	4.694
chr6_-_11887265	3.551	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr6_-_6632197	2.977
chr9_-_99740243	2.925	NM_197978	HEMGN	hemogen
chr10_+_5976354	2.854	NM_032807	FBXO18	F-box protein, helicase, 18
chr22_+_20316968	2.631	NM_152612	CCDC116	coiled-coil domain containing 116
chr2_-_17563186	2.426	NM_001099218	RAD51AP2	RAD51 associated protein 2
chr14_+_19655405	2.298	NM_001004715	OR4K17	olfactory receptor, family 4, subfamily K, member 17
chr12_-_55929189	2.293
chr7_-_142369519	2.084		KEL	Kell blood group, metallo-endopeptidase
chr1_-_158815895	2.067	NM_001184879 NM_001184881 NM_001184882 NM_003874	CD84	CD84 molecule
chr1_-_205161821	2.001	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr2_-_158008763	1.851	NM_004288	CYTIP	cytohesin 1 interacting protein
chr1_-_158815850	1.729		CD84	CD84 molecule
chr10_+_51246290	1.662	NM_001145262	NCOA4	nuclear receptor coactivator 4
chr6_-_25982418	1.654	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr1_+_205694237	1.618	NM_001006658 NM_001877	CR2	complement component (3d/Epstein Barr virus) receptor 2
chr1_+_173111306	1.608	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr6_-_154719560	1.579	NM_001130700 NM_015553	IPCEF1	interaction protein for cytohesin exchange factors 1
chr6_+_144227265	1.550	NM_001013623	C6orf94	chromosome 6 open reading frame 94
chr7_-_142369534	1.501	NM_000420	KEL	Kell blood group, metallo-endopeptidase
chr6_+_64414389	1.396	NM_015153	PHF3	PHD finger protein 3
chr3_-_19950675	1.314	NM_144715	EFHB	EF-hand domain family, member B
chr5_+_34723420	1.309	NM_001145523	RAI14	retinoic acid induced 14
chr17_-_31281398	1.302	NM_001163122 NM_001163124 NM_001163125 NM_001163130	RDM1	RAD52 motif 1
chr19_+_17723285	1.284	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr6_-_32605898	1.222	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr16_+_31446703	1.217	NM_016633	AHSP	alpha hemoglobin stabilizing protein
chr8_-_110724594	1.217	NM_001099756	SYBU	syntabulin (syntaxin-interacting)
chr1_+_159959072	1.206	NM_001002901	FCRLB	Fc receptor-like B
chr10_+_49563520	1.191	NM_020945	WDFY4	WDFY family member 4
chr2_+_102401580	1.181	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr10_-_106083652	1.178	NM_033397	ITPRIP	inositol 1,4,5-triphosphate receptor interacting protein
chr11_-_56914668	1.175	NM_002728	PRG2	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr21_-_33107813	1.175	NM_001162495 NM_001162496 NM_019596	C21orf62	chromosome 21 open reading frame 62
chr2_+_65517316	1.169		FLJ16124	FLJ16124 protein
chr6_+_47774247	1.114	NM_153838	GPR115	G protein-coupled receptor 115
chr12_+_46802695	1.109	NM_001166687 NM_001166688	PFKM	phosphofructokinase, muscle
chr1_-_151310707	1.089	NM_001017418	SPRR2B	small proline-rich protein 2B
chr8_+_107807415	1.074	NM_001198534 NM_001198535	OXR1	oxidation resistance 1
chr1_+_190811479	1.050	NM_002922	RGS1	regulator of G-protein signaling 1
chr16_+_2807228	1.023		PRSS21	protease, serine, 21 (testisin)
chrX_+_153423652	1.021	NM_001099856	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr7_+_21434818	1.019
chr15_+_41672543	0.995	NM_020990	CKMT1B CKMT1A	creatine kinase, mitochondrial 1B creatine kinase, mitochondrial 1A
chr6_-_32665409	0.992	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr11_-_5487728	0.992	NM_017481	UBQLN3	ubiquilin 3
chr15_-_91078307	0.977		FAM174B	family with sequence similarity 174, member B
chr19_-_50271527	0.962	NM_145288	ZNF296	zinc finger protein 296
chr21_-_32879617	0.955	NM_144659	TCP10L	t-complex 10 (mouse)-like
chr1_-_151333624	0.947	NM_001024209	SPRR2E	small proline-rich protein 2E
chr11_+_59580705	0.946		MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chrX_+_134803450	0.943	NM_018666	SAGE1	sarcoma antigen 1
chr17_+_49255237	0.933	NM_032559	KIF2B	kinesin family member 2B
chr1_+_116727514	0.925	NM_001160234	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_-_10309600	0.907	NM_001134944 NM_001134945 NM_001134946	GHRL	ghrelin/obestatin prepropeptide
chr19_-_44060729	0.902	NM_001195833 NM_198445	RINL	Ras and Rab interactor-like
chr6_+_106653429	0.881	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr19_-_60458915	0.841		PPP6R1	protein phosphatase 6, regulatory subunit 1
chr8_+_124263932	0.840	NM_032899 NM_207006	FAM83A	family with sequence similarity 83, member A
chr2_-_157892391	0.839	NM_001009959	ERMN	ermin, ERM-like protein
chr12_-_8110268	0.833		C3AR1	complement component 3a receptor 1
chr12_-_8110196	0.832	NM_004054	C3AR1	complement component 3a receptor 1
chr4_-_145281237	0.826	NM_002099	GYPA	glycophorin A (MNS blood group)
chr6_+_88026338	0.809		ZNF292	zinc finger protein 292
chr12_-_10479810	0.805	NM_002260	KLRC2 KLRC3	killer cell lectin-like receptor subfamily C, member 2 killer cell lectin-like receptor subfamily C, member 3
chr6_+_31016755	0.805	NM_080870	DPCR1	diffuse panbronchiolitis critical region 1
chr16_+_2807164	0.797	NM_006799 NM_144956 NM_144957	PRSS21	protease, serine, 21 (testisin)
chr16_+_56567839	0.789	NM_199046 NM_199456	TEPP	testis, prostate and placenta expressed
chr7_+_141124710	0.781	NM_016944	TAS2R4	taste receptor, type 2, member 4
chr1_+_40631603	0.778	NM_001198979	SMAP2	small ArfGAP2
chr22_+_19458378	0.768	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr18_+_3584056	0.764		FLJ35776	hypothetical LOC649446
chr1_+_23994914	0.721
chr15_-_41300488	0.721		EPB42	erythrocyte membrane protein band 4.2
chr17_-_59825221	0.714
chr6_+_43060304	0.684		PPP2R5D	protein phosphatase 2, regulatory subunit B', delta
chr8_+_9990471	0.684	NM_001135671	MSRA	methionine sulfoxide reductase A
chr11_+_58668827	0.680	NM_022074 NM_198847	FAM111A	family with sequence similarity 111, member A
chr11_+_59580630	0.671	NM_001031666 NM_001031809 NM_006138	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr17_-_8215577	0.664	NM_213597	KRBA2	KRAB-A domain containing 2
chr6_-_11490487	0.653	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr7_-_107667728	0.650	NM_001037132	NRCAM	neuronal cell adhesion molecule
chr4_+_22608252	0.641
chr1_+_156490550	0.609	NM_001763	CD1A	CD1a molecule
chr5_+_40877053	0.608	NM_032587	CARD6	caspase recruitment domain family, member 6
chr11_-_5247948	0.604	NM_005330	HBE1	hemoglobin, epsilon 1
chr15_-_78050515	0.603	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr1_+_245779018	0.603	NM_145278	C1orf150	chromosome 1 open reading frame 150
chr17_-_64752550	0.595	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr9_+_124072947	0.593	NM_199177	MRRF	mitochondrial ribosome recycling factor
chr11_-_72057755	0.592	NM_001146209	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr19_-_6671585	0.590	NM_000064	C3	complement component 3
chr19_+_56958452	0.586	NM_001462	FPR2	formyl peptide receptor 2
chr1_+_67404756	0.578	NM_144701	IL23R	interleukin 23 receptor
chr11_-_123414917	0.565	NM_001004463	OR10G7	olfactory receptor, family 10, subfamily G, member 7
chr11_-_57275828	0.563	NM_001145101	BTBD18	BTB (POZ) domain containing 18
chr14_-_106352471	0.560
chr11_-_123758448	0.557	NM_001005468	OR8B2	olfactory receptor, family 8, subfamily B, member 2
chr6_-_27988152	0.554	NM_033057	OR2B2	olfactory receptor, family 2, subfamily B, member 2
chr10_-_50012058	0.548	NM_001164484	FAM170B	family with sequence similarity 170, member B
chr17_-_64462976	0.546	NM_007168	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr11_+_124329222	0.539	NM_025004	CCDC15	coiled-coil domain containing 15
chr1_+_46418786	0.539		TSPAN1	tetraspanin 1
chrX_-_135691168	0.529	NM_004840	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_-_51560469	0.529	NM_001080494	TTC39A	tetratricopeptide repeat domain 39A
chr1_+_86942810	0.521	NM_016009	SH3GLB1	SH3-domain GRB2-like endophilin B1
chr22_+_16423147	0.518	NM_031481	SLC25A18	solute carrier family 25 (mitochondrial carrier), member 18
chr10_-_91092410	0.517		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr1_-_149004852	0.516		CTSS	cathepsin S
chr1_+_196874759	0.513	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr18_+_70317802	0.509	NM_001168499	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr6_+_31838751	0.502	NM_001039651	C6orf26	chromosome 6 open reading frame 26
chr6_+_88111289	0.502	NM_001010868	C6orf163	chromosome 6 open reading frame 163
chr5_+_67622242	0.496	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_10453409	0.494	NM_013431	KLRC4-KLRK1 KLRC4	KLRC4-KLRK1 read-through transcript killer cell lectin-like receptor subfamily C, member 4
chr9_-_138762725	0.492	NM_198946	LCN6	lipocalin 6
chr6_-_38671741	0.491	NM_001172418 NM_152733	BTBD9	BTB (POZ) domain containing 9
chr19_+_47073029	0.483	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr1_+_154390939	0.478		SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_+_133060353	0.475		EFR3A	EFR3 homolog A (S. cerevisiae)
chr11_-_117718532	0.473	NM_000732 NM_001040651	CD3D	CD3d molecule, delta (CD3-TCR complex)
chr6_-_109795925	0.472		CD164	CD164 molecule, sialomucin
chrX_-_135690770	0.471		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr3_-_15773061	0.471	NM_001195099	ANKRD28	ankyrin repeat domain 28
chr19_+_56990222	0.463	NM_002030	FPR3	formyl peptide receptor 3
chr5_-_37220702	0.458		C5orf42	chromosome 5 open reading frame 42
chr6_+_28601767	0.454	NM_001509 NM_003996	GPX5	glutathione peroxidase 5 (epididymal androgen-related protein)
chr14_-_34414603	0.453	NM_013448 NM_182648	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr19_+_39402167	0.449		LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)
chr1_-_151296611	0.445	NM_005988	SPRR2A	small proline-rich protein 2A
chr11_+_59027624	0.442	NM_001004706	OR4D11	olfactory receptor, family 4, subfamily D, member 11
chrX_-_84250629	0.441	NM_001012980	SATL1	spermidine/spermine N1-acetyl transferase-like 1
chr12_+_49604782	0.437	NM_014033	METTL7A	methyltransferase like 7A
chr5_-_110090264	0.435	NM_001039763	TMEM232	transmembrane protein 232
chr3_-_173723754	0.434	NM_001190943 NM_001190942 NM_003810	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
chr14_+_77939845	0.428	NM_004796	NRXN3	neurexin 3
chr14_-_20694023	0.426	NM_001004731	OR5AU1	olfactory receptor, family 5, subfamily AU, member 1
chr2_-_169596078	0.424	NM_003742	ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr11_+_124329286	0.422		CCDC15	coiled-coil domain containing 15
chr17_+_36636404	0.420	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr7_+_143331954	0.417	NM_001005281	OR6B1	olfactory receptor, family 6, subfamily B, member 1
chr11_+_63730720	0.417	NM_031471 NM_178443	FERMT3	fermitin family member 3
chr17_+_72827968	0.416		SEPT9	septin 9
chr2_+_165860528	0.414	NM_001040143	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr7_-_133652042	0.413		SLC35B4	solute carrier family 35, member B4
chr4_-_90197140	0.412	NM_014883	FAM13A	family with sequence similarity 13, member A
chr2_-_39310176	0.410	NM_001009565	CDKL4	cyclin-dependent kinase-like 4
chr1_-_100416358	0.410	NM_144620	LRRC39	leucine rich repeat containing 39
chr17_-_35327318	0.404	NM_018530	GSDMB	gasdermin B
chr15_+_62578671	0.403	NM_015042	ZNF609	zinc finger protein 609
chr12_-_10215942	0.397	NM_001172632 NM_001172633 NM_002543	OLR1	oxidized low density lipoprotein (lectin-like) receptor 1
chr12_+_6424293	0.393	NM_001242	CD27	CD27 molecule
chr10_-_45350804	0.392	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr3_+_153468518	0.388	NM_021038 NM_207292	MBNL1	muscleblind-like (Drosophila)
chr3_-_50583425	0.386	NM_001171741	C3orf18	chromosome 3 open reading frame 18
chr15_-_48198697	0.369	NM_024837	ATP8B4	ATPase, class I, type 8B, member 4
chr11_-_62231242	0.365		BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_-_45988901	0.364	NM_001145349 NM_005897	IPP	intracisternal A particle-promoted polypeptide
chr11_+_59001421	0.361	NM_001004705	OR4D10	olfactory receptor, family 4, subfamily D, member 10
chr7_-_16471817	0.357	NM_015464	SOSTDC1	sclerostin domain containing 1
chr13_+_107753764	0.356
chr6_+_29187565	0.347	NM_001005216	OR2J3	olfactory receptor, family 2, subfamily J, member 3
chr19_-_49076080	0.343	NM_001033719	ZNF404	zinc finger protein 404
chr2_-_215605054	0.340	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr4_+_95595419	0.339		PDLIM5	PDZ and LIM domain 5
chrX_+_16051344	0.339	NM_005314	GRPR	gastrin-releasing peptide receptor
chr14_+_36200867	0.338		PAX9	paired box 9
chr6_+_33151703	0.337	NM_002121	HLA-DPB1	major histocompatibility complex, class II, DP beta 1
chr3_-_180467483	0.336	NM_001163677 NM_171828	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr20_+_29492071	0.332	NM_153324	DEFB123	defensin, beta 123
chr10_-_50402148	0.331	NM_170753	PGBD3	piggyBac transposable element derived 3
chr3_+_142175329	0.328		SLC25A36	solute carrier family 25, member 36
chr1_+_51968191	0.327		OSBPL9	oxysterol binding protein-like 9
chr10_+_97505398	0.326	NM_001164178 NM_001164181 NM_001164179 NM_001164182 NM_001164183 NM_001776	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr2_+_143351536	0.320	NM_001032998 NM_003937	KYNU	kynureninase
chr2_+_169631777	0.319	NM_199204	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr8_-_30826074	0.318	NM_031271	TEX15	testis expressed 15
chr8_+_7731402	0.317	NM_080389 NM_001040702	DEFB104A DEFB104B	defensin, beta 104A defensin, beta 104B
chr3_-_113334657	0.316	NM_001190259 NM_001190260 NM_152785	GCET2	germinal center expressed transcript 2
chr6_-_88095714	0.314	NM_198568	GJB7	gap junction protein, beta 7, 25kDa
chr6_+_31698447	0.309
chr15_+_19869841	0.306	NM_001004719	OR4M2	olfactory receptor, family 4, subfamily M, member 2
chr10_-_69422391	0.306		HERC4	hect domain and RLD 4
chr1_-_7923464	0.303	NM_001561	TNFRSF9	tumor necrosis factor receptor superfamily, member 9
chr7_+_102176561	0.300	NM_001145268 NM_001145269	FAM185A	family with sequence similarity 185, member A
chr7_-_92585205	0.299		SAMD9	sterile alpha motif domain containing 9
chr22_-_35829402	0.298	NM_153609	TMPRSS6	transmembrane protease, serine 6
chr6_+_37895244	0.297	NM_021943	ZFAND3	zinc finger, AN1-type domain 3
chr1_-_149004916	0.297	NM_004079	CTSS	cathepsin S
chr10_-_37931864	0.292	NM_001190489	MTRNR2L7	MT-RNR2-like 7
chr2_-_55090759	0.289	NM_007008	RTN4	reticulon 4
chr7_-_92585253	0.289	NM_001193307 NM_017654	SAMD9	sterile alpha motif domain containing 9
chr11_+_123945102	0.288	NM_001005194	OR8A1	olfactory receptor, family 8, subfamily A, member 1
chr18_-_53438854	0.287
chr3_+_99350859	0.287	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr4_-_140280031	0.285	NM_201999	ELF2	E74-like factor 2 (ets domain transcription factor)
chr7_-_30032649	0.282	NM_017946	FKBP14	FK506 binding protein 14, 22 kDa

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.05	1.60e-05	GO:0007608	sensory perception of smell
2.81	7.16e-05	GO:0007606	sensory perception of chemical stimulus
3.20	6.87e-04	GO:0050778	positive regulation of immune response
2.19	8.11e-04	GO:0006952	defense response
5.00	9.08e-04	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.31	1.03e-03	GO:0050896	response to stimulus
4.81	1.47e-03	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.86	3.72e-03	GO:0002376	immune system process
2.57	4.33e-03	GO:0002684	positive regulation of immune system process
3.22	9.55e-03	GO:0002253	activation of immune response
3.28	3.97e-02	GO:0002696	positive regulation of leukocyte activation
2.36	4.22e-02	GO:0050776	regulation of immune response
3.23	4.89e-02	GO:0050867	positive regulation of cell activation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.48	1.88e-06	GO:0071944	cell periphery
1.48	3.90e-06	GO:0005886	plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.15	1.38e-07	GO:0004888	transmembrane receptor activity
1.91	8.63e-07	GO:0004872	receptor activity
3.19	1.11e-06	GO:0004984	olfactory receptor activity
2.29	9.20e-06	GO:0004930	G-protein coupled receptor activity
1.71	2.85e-05	GO:0004871	signal transducer activity
1.71	2.85e-05	GO:0060089	molecular transducer activity
6.31	2.92e-02	GO:0003823	antigen binding