Motif ID: GATA1..3.p2

Z-value: 2.692


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3



Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_5534252 2.746 ACTB
actin, beta
chr12_-_48902692 2.498 NM_001113547
LIMA1
LIM domain and actin binding 1
chrX_+_53095230 2.474 NM_018969
GPR173
G protein-coupled receptor 173
chr2_-_189752575 2.415 NM_000393
COL5A2
collagen, type V, alpha 2
chr7_-_81237162 2.318 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr6_-_74284522 2.272 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr8_-_108579270 2.209 NM_001146
ANGPT1
angiopoietin 1
chr3_-_129023850 1.969 NM_007283
MGLL
monoglyceride lipase
chr7_-_5534737 1.925 ACTB
actin, beta
chr8_-_11096257 1.890 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr8_-_93176819 1.866 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_35503720 1.866 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr6_+_30799130 1.823 TUBB
tubulin, beta
chr4_-_138673078 1.760 NM_019035
PCDH18
protocadherin 18
chr1_+_81544432 1.745 LPHN2
latrophilin 2
chr11_-_85107569 1.742 NM_206929
SYTL2
synaptotagmin-like 2
chr19_-_55008172 1.703 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr20_+_19903778 1.693 RIN2
Ras and Rab interactor 2
chr3_+_144321286 1.634 NM_004267
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr9_-_16717887 1.615 BNC2
basonuclin 2
chr9_+_134026836 1.577 NTNG2
netrin G2
chr10_-_105427898 1.570 SH3PXD2A
SH3 and PX domains 2A
chr4_+_134292630 1.565 PCDH10
protocadherin 10
chr8_-_93176618 1.553 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr5_+_140871107 1.537


chr15_+_41597097 1.476 NM_002373
MAP1A
microtubule-associated protein 1A
chr4_-_138673014 1.447 PCDH18
protocadherin 18
chr6_-_119137923 1.404 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr4_+_134293171 1.389 PCDH10
protocadherin 10
chr2_-_213723298 1.380 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr7_+_18501876 1.358 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr3_-_145049853 1.351 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr1_+_162795538 1.348 PBX1
pre-B-cell leukemia homeobox 1
chr12_+_52733927 1.346 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr1_-_226712140 1.341 NM_033445
HIST3H2A
histone cluster 3, H2a
chr6_-_26379567 1.329 NM_003534
HIST1H3G
histone cluster 1, H3g
chr8_+_70541631 1.310 SULF1
sulfatase 1
chr8_-_93144366 1.302 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93144039 1.285


chrX_-_154216929 1.284 NM_001289
CLIC2
chloride intracellular channel 2
chr8_-_93099040 1.276 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_140870881 1.260


chr1_+_226712430 1.258 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr22_-_43272100 1.230 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr18_-_51219880 1.206 TCF4
transcription factor 4
chr15_+_45797977 1.175 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chrX_-_135941498 1.158 NM_054021
GPR101
G protein-coupled receptor 101
chr5_+_176494690 1.148 NSD1
nuclear receptor binding SET domain protein 1
chr11_+_131285747 1.147 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr12_+_46799279 1.130 NM_000289
PFKM
phosphofructokinase, muscle
chr8_-_25958291 1.122 NM_022659
EBF2
early B-cell factor 2
chr9_+_70161634 1.119 NM_021965
PGM5
phosphoglucomutase 5
chr20_-_56859352 1.118 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr1_+_170077234 1.110 NM_001136127
NM_015569
DNM3

dynamin 3

chr2_-_144994349 1.086 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr3_-_9969057 1.074 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr9_+_18464138 1.069 ADAMTSL1
ADAMTS-like 1
chr4_+_81406765 1.058 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr5_-_139924229 1.043 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr7_+_143263191 1.040 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr2_-_144994038 1.036 ZEB2
zinc finger E-box binding homeobox 2
chr17_-_45629401 1.025


chr5_+_82803248 1.011 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr6_-_80713589 0.998 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr15_+_55298908 0.995 NM_207040
TCF12
transcription factor 12
chr17_-_45626364 0.991


chr12_+_79625538 0.989 NM_002469
MYF6
myogenic factor 6 (herculin)
chrX_-_57953578 0.982 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr13_-_32678142 0.979 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr21_-_35153664 0.969 RUNX1
runt-related transcription factor 1
chr3_-_11598829 0.964 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr17_-_77092569 0.962 ACTG1
actin, gamma 1
chr16_+_88305743 0.957 LOC100128881
hypothetical LOC100128881
chr3_-_71262426 0.956 FOXP1
forkhead box P1
chr11_-_85108030 0.951 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr3_-_55489973 0.951 WNT5A
wingless-type MMTV integration site family, member 5A
chr9_+_134027154 0.946 NM_032536
NTNG2
netrin G2
chr5_-_158459276 0.934 NM_024007
EBF1
early B-cell factor 1
chr3_+_179736917 0.928 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr17_-_45633873 0.922 COL1A1
collagen, type I, alpha 1
chr10_-_79067210 0.920 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr18_-_50004458 0.915 MBD2
methyl-CpG binding domain protein 2
chr5_-_88214720 0.915 MEF2C
myocyte enhancer factor 2C
chr8_-_18585721 0.910 PSD3
pleckstrin and Sec7 domain containing 3
chr9_+_76302071 0.904 NM_006914
RORB
RAR-related orphan receptor B
chr19_-_45888259 0.895 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr3_+_142587973 0.893


chr8_+_70541412 0.893 NM_001128204
NM_015170
SULF1

sulfatase 1

chr6_+_33151703 0.881 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr6_-_130224108 0.879 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr1_+_162795328 0.876 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr2_+_157822355 0.869 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr10_+_75343352 0.862 PLAU
plasminogen activator, urokinase
chr1_+_200775864 0.859 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr3_-_113841448 0.848 CCDC80
coiled-coil domain containing 80
chr8_-_93177057 0.847 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr2_-_144991386 0.847 ZEB2
zinc finger E-box binding homeobox 2
chr1_-_26517342 0.843 NM_145345
UBXN11
UBX domain protein 11
chr8_-_25958556 0.834 EBF2
early B-cell factor 2
chr9_+_123501186 0.832 DAB2IP
DAB2 interacting protein
chr4_+_160408447 0.831 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr12_+_103375116 0.828 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chrX_+_51503219 0.823 NM_018094
GSPT2
G1 to S phase transition 2
chr3_-_71262405 0.822 FOXP1
forkhead box P1
chr8_+_70567634 0.820 SULF1
sulfatase 1
chr17_-_44641741 0.819 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr12_-_15005761 0.815 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_66772393 0.814 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_+_18464090 0.814 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr9_-_35608300 0.812 NM_001782
CD72
CD72 molecule
chr1_-_72520735 0.809 NM_173808
NEGR1
neuronal growth regulator 1
chr17_+_39990124 0.804 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr14_+_95792299 0.803 NM_000710
BDKRB1
bradykinin receptor B1
chr11_-_62233552 0.798 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_+_67558217 0.797 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_+_70567581 0.797 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr5_+_139924224 0.792 SLC35A4
solute carrier family 35, member A4
chr15_-_81667169 0.789 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr2_-_144991556 0.789 ZEB2
zinc finger E-box binding homeobox 2
chr13_-_101852028 0.787 NM_175929
FGF14
fibroblast growth factor 14
chr11_+_5610060 0.782 NM_130390
TRIM34
tripartite motif containing 34
chr11_-_47427263 0.780 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr2_-_39040981 0.780 LOC375196
hypothetical LOC375196
chr1_-_153509473 0.779 NM_003993
CLK2
CDC-like kinase 2
chr11_-_95715976 0.769 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr6_-_78229838 0.764 NM_000863
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr10_-_79067552 0.762 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr10_-_79067476 0.757 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_55496607 0.754 WNT5A
wingless-type MMTV integration site family, member 5A
chr7_+_90176647 0.753 NM_012395
CDK14
cyclin-dependent kinase 14
chr16_-_87570716 0.753 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr18_-_65766068 0.750 CD226
CD226 molecule
chr7_+_128795178 0.748 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr13_-_105985313 0.748 NM_004093
EFNB2
ephrin-B2
chr6_-_101018271 0.744 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chr15_+_39032927 0.743 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr1_+_234372454 0.743 NM_003272
GPR137B
G protein-coupled receptor 137B
chr5_-_124108672 0.741 NM_020747
ZNF608
zinc finger protein 608
chr12_+_79634820 0.739 NM_005593
MYF5
myogenic factor 5
chr6_+_26128656 0.738 NM_003529
HIST1H3A
histone cluster 1, H3a
chr15_-_78050515 0.731 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr1_+_154095883 0.729 NM_152280
SYT11
synaptotagmin XI
chr17_-_44022595 0.727 HOXB3
homeobox B3
chr10_+_18669619 0.725 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr10_+_70517863 0.712 SRGN
serglycin
chrX_+_78087484 0.712 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr11_-_133332089 0.711 NM_014987
IGSF9B
immunoglobulin superfamily, member 9B
chr2_-_38156769 0.709 CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr5_+_36644187 0.703 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_77782719 0.702 SYT1
synaptotagmin I
chr9_+_112470871 0.701 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr3_+_49002774 0.699 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr10_+_70517823 0.696 NM_002727
SRGN
serglycin
chr3_+_49002285 0.693 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr7_+_128795280 0.690 AHCYL2
adenosylhomocysteinase-like 2
chr10_-_79067400 0.689 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_76259976 0.677 NM_015687
FILIP1
filamin A interacting protein 1
chr1_+_207823667 0.670 NM_020439
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr17_+_7199178 0.670 NM_198154
TMEM95
transmembrane protein 95
chr12_+_79362256 0.662 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr13_+_100902942 0.662 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_-_85816520 0.657 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_189547358 0.657 COL3A1
collagen, type III, alpha 1
chr7_+_50318801 0.650 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr10_-_105202139 0.645 NM_015916
CALHM2
calcium homeostasis modulator 2
chr13_-_107317460 0.644 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr17_-_44026042 0.639 NM_002147
HOXB5
homeobox B5
chr1_-_42157077 0.635 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr5_+_140733664 0.635 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr4_+_75449720 0.634 NM_001432
EREG
epiregulin
chr14_+_64077171 0.632 HSPA2
heat shock 70kDa protein 2
chr22_-_35970133 0.631 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_-_52281050 0.631 NM_001130059
ATF7
activating transcription factor 7
chr17_-_43977273 0.629 NM_002145
HOXB2
homeobox B2
chr12_-_51912101 0.629 NM_000966
RARG
retinoic acid receptor, gamma
chr6_+_6533932 0.627 NM_004271
LY86
lymphocyte antigen 86
chr11_+_63730720 0.626 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr2_-_167058829 0.626 SCN7A
sodium channel, voltage-gated, type VII, alpha
chr10_-_105202012 0.624 CALHM2
calcium homeostasis modulator 2
chr22_-_43271843 0.623 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr3_-_113841200 0.623 CCDC80
coiled-coil domain containing 80
chr14_+_101346032 0.619 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr12_+_77782579 0.615 NM_005639
SYT1
synaptotagmin I
chr1_-_42156913 0.614


chr15_-_54322767 0.614 NM_022841
RFX7
regulatory factor X, 7
chr3_-_55496370 0.613 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr3_+_99733432 0.612 NM_005290
GPR15
G protein-coupled receptor 15
chr2_+_189547323 0.611 NM_000090
COL3A1
collagen, type III, alpha 1
chr7_+_120756325 0.611 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr2_-_215711313 0.610 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr12_+_56206692 0.608 MBD6
methyl-CpG binding domain protein 6
chr2_-_167058901 0.607 SCN7A
sodium channel, voltage-gated, type VII, alpha
chr2_+_189547377 0.597 COL3A1
collagen, type III, alpha 1
chr10_-_75005421 0.593 NM_152586
USP54
ubiquitin specific peptidase 54
chr2_-_29150630 0.592 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr11_+_58146721 0.590 NM_000614
CNTF
ciliary neurotrophic factor
chr10_-_100985548 0.588 NM_001166244
NM_001166245
NM_001166246
NM_021828
HPSE2



heparanase 2



chr8_-_116750427 0.588 TRPS1
trichorhinophalangeal syndrome I
chr17_-_77092831 0.587 ACTG1
actin, gamma 1
chr3_+_190831909 0.587 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.20 8.02e-17 GO:0032501 multicellular organismal process
1.81 2.80e-15 GO:0007608 sensory perception of smell
1.76 6.00e-15 GO:0007606 sensory perception of chemical stimulus
1.42 4.18e-14 GO:0050877 neurological system process
1.37 7.35e-14 GO:0003008 system process
1.15 8.43e-11 GO:0050896 response to stimulus
1.48 2.53e-10 GO:0007600 sensory perception
1.19 2.41e-05 GO:0048731 system development
1.16 3.23e-05 GO:0023052 signaling
1.16 1.35e-04 GO:0007275 multicellular organismal development
1.16 1.98e-04 GO:0048856 anatomical structure development
1.15 4.41e-04 GO:0007165 signal transduction
1.14 6.92e-04 GO:0032502 developmental process
1.24 1.14e-03 GO:0007399 nervous system development
1.39 8.32e-03 GO:0019226 transmission of nerve impulse
1.39 8.32e-03 GO:0035637 multicellular organismal signaling
1.41 9.69e-03 GO:0007268 synaptic transmission
1.15 1.48e-02 GO:0048518 positive regulation of biological process
1.08 2.37e-02 GO:0050794 regulation of cellular process
1.11 3.18e-02 GO:0051716 cellular response to stimulus
1.29 3.62e-02 GO:0007267 cell-cell signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 3.98e-04 GO:0005886 plasma membrane
1.14 4.51e-04 GO:0032991 macromolecular complex
1.12 1.05e-03 GO:0071944 cell periphery
1.41 2.22e-03 GO:0043005 neuron projection
1.03 5.76e-03 GO:0005623 cell
1.03 6.91e-03 GO:0044464 cell part
1.13 1.03e-02 GO:0043234 protein complex
1.57 1.37e-02 GO:0030424 axon
1.37 1.56e-02 GO:0045202 synapse
1.55 2.88e-02 GO:0043025 neuronal cell body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.84 5.55e-16 GO:0004984 olfactory receptor activity
1.43 4.94e-09 GO:0004930 G-protein coupled receptor activity
1.29 6.21e-06 GO:0004888 transmembrane receptor activity
1.20 9.90e-05 GO:0004871 signal transducer activity
1.20 9.90e-05 GO:0060089 molecular transducer activity
1.22 1.24e-04 GO:0004872 receptor activity
1.09 1.51e-04 GO:0005515 protein binding
1.25 6.97e-03 GO:0030528 transcription regulator activity