Motif ID: GFI1.p2

Z-value: 2.935


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor



Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_23816062 5.477 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_+_183302105 5.460 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr5_+_174084137 4.075 NM_002449
MSX2
msh homeobox 2
chr7_-_27162688 3.887 NM_006896
HOXA7
homeobox A7
chr8_-_41286088 3.671 NM_003012
SFRP1
secreted frizzled-related protein 1
chr6_+_26333361 3.237 NM_003532
HIST1H3E
histone cluster 1, H3e
chr5_+_66160359 3.198 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_-_189752575 3.182 NM_000393
COL5A2
collagen, type V, alpha 2
chr2_-_45090025 3.053 NM_016932
SIX2
SIX homeobox 2
chr5_-_127901633 3.003 NM_001999
FBN2
fibrillin 2
chr1_-_68470585 2.957 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr4_-_138673078 2.867 NM_019035
PCDH18
protocadherin 18
chr4_-_138673014 2.815 PCDH18
protocadherin 18
chr11_-_8849485 2.771 ST5
suppression of tumorigenicity 5
chr4_+_167013859 2.717 NM_012464
TLL1
tolloid-like 1
chr4_-_122063118 2.641 NM_018699
PRDM5
PR domain containing 5
chr4_-_115120251 2.638 NM_024590
ARSJ
arylsulfatase family, member J
chr10_+_102782156 2.579 SFXN3
sideroflexin 3
chr7_-_121571472 2.456 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr19_-_11352850 2.399 EPOR
erythropoietin receptor
chr10_+_102782151 2.383 SFXN3
sideroflexin 3
chr8_-_49996353 2.379 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr6_-_26379567 2.364 NM_003534
HIST1H3G
histone cluster 1, H3g
chrX_+_17665483 2.291 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr18_+_42780784 2.273 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr7_+_87095640 2.244 NM_001134405
NM_001134406
NM_138290
RUNDC3B


RUN domain containing 3B


chr4_-_76774594 2.213 NM_003948
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr3_-_87122958 2.205 VGLL3
vestigial like 3 (Drosophila)
chr16_+_81218074 2.158 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr3_-_87122936 2.121 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr2_+_149895274 2.079 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr22_-_26527469 2.048 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr4_+_95898098 2.036 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr11_-_127897098 2.000 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr6_+_26153590 1.995 NM_003531
HIST1H3C
histone cluster 1, H3c
chr12_+_83954229 1.991 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr1_-_95165037 1.974 CNN3
calponin 3, acidic
chr1_-_95165089 1.955 NM_001839
CNN3
calponin 3, acidic
chrX_+_56275510 1.943 NM_007250
NM_001159296
KLF8

Kruppel-like factor 8

chr17_+_67628772 1.882 SOX9
SRY (sex determining region Y)-box 9
chr11_-_40272239 1.872 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr6_-_166960496 1.868 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_+_67628749 1.861 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr4_+_321587 1.845 NM_003441
ZNF141
zinc finger protein 141
chr4_+_321607 1.836 ZNF141
zinc finger protein 141
chr11_-_72111027 1.829 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr12_+_77782719 1.811 SYT1
synaptotagmin I
chr6_-_166960649 1.810 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_36688556 1.783 NM_145047
NM_206837
OSCP1

organic solute carrier partner 1

chr15_+_39032927 1.760 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr5_-_124108672 1.751 NM_020747
ZNF608
zinc finger protein 608
chr8_-_98359248 1.745 TSPYL5
TSPY-like 5
chr19_-_63643400 1.734 NM_003433
ZNF132
zinc finger protein 132
chr11_+_13255836 1.716 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr3_+_112876212 1.689 NM_001185106
NM_153268
PLCXD2

phosphatidylinositol-specific phospholipase C, X domain containing 2

chr5_+_140835788 1.685 PCDHGC3
protocadherin gamma subfamily C, 3
chr4_+_77829634 1.684 SHROOM3
shroom family member 3
chr17_+_67628763 1.661 SOX9
SRY (sex determining region Y)-box 9
chr13_-_77391525 1.648


chr17_+_4922478 1.644 ZFP3
zinc finger protein 3 homolog (mouse)
chr9_-_83494198 1.643 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr3_-_147361912 1.634 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr5_-_92942680 1.634 FLJ42709
hypothetical LOC441094
chr11_+_13255925 1.630 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr17_+_4922445 1.623 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chrX_-_10548458 1.616 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr19_-_12128528 1.605 NM_145233
ZNF625-ZNF20
ZNF625
ZNF625-ZNF20 read-through transcript
zinc finger protein 625
chr11_-_133332089 1.596 NM_014987
IGSF9B
immunoglobulin superfamily, member 9B
chr3_+_50248749 1.595 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr14_-_51605461 1.585 NID2
nidogen 2 (osteonidogen)
chr14_-_51605487 1.572 NID2
nidogen 2 (osteonidogen)
chr20_+_43875078 1.567 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr11_+_43658718 1.562 NM_016142
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr11_+_13255948 1.555 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13255913 1.549 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr10_-_101680645 1.533 DNMBP
dynamin binding protein
chr5_+_140835727 1.524 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr11_-_118799058 1.524 THY1
Thy-1 cell surface antigen
chr2_+_149894744 1.511 NM_001195685
LYPD6
LY6/PLAUR domain containing 6
chr14_-_51605515 1.511 NID2
nidogen 2 (osteonidogen)
chr17_-_17816425 1.505 NM_001033551
NM_001082968
TOM1L2

target of myb1-like 2 (chicken)

chr15_-_81744469 1.503 NM_001717
BNC1
basonuclin 1
chr17_-_30783631 1.499 NM_018042
SLFN12
schlafen family member 12
chr12_-_83954185 1.494 NM_001100917
TSPAN19
tetraspanin 19
chr8_-_98359347 1.492 NM_033512
TSPYL5
TSPY-like 5
chr17_-_67628523 1.491 FLJ37644
hypothetical LOC400618
chr1_+_66570683 1.479 PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_13255905 1.478 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr1_+_218768423 1.461 MARK1
MAP/microtubule affinity-regulating kinase 1
chr9_-_20612476 1.454 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr14_-_51605695 1.451 NM_007361
NID2
nidogen 2 (osteonidogen)
chr2_-_216944911 1.450 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr7_-_27153892 1.439 NM_024014
HOXA6
homeobox A6
chrX_+_103103848 1.438 NM_194324
TMSB15B
thymosin beta 15B
chr4_+_77829743 1.435 SHROOM3
shroom family member 3
chr14_-_57834558 1.430 FLJ31306
hypothetical LOC379025
chr1_+_82038669 1.426 NM_012302
LPHN2
latrophilin 2
chr14_+_103251798 1.424 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr9_+_136673534 1.421 COL5A1
collagen, type V, alpha 1
chr12_+_77782579 1.420 NM_005639
SYT1
synaptotagmin I
chr11_+_13255952 1.419 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr3_+_114414064 1.418 NM_033254
BOC
Boc homolog (mouse)
chr20_+_43874735 1.417 UBE2C
ubiquitin-conjugating enzyme E2C
chr11_+_13255967 1.409 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr7_-_133794344 1.408 AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr1_+_112740378 1.394


chr1_+_161305558 1.386 NM_001113381
RGS4
regulator of G-protein signaling 4
chr3_-_69517913 1.384 FRMD4B
FERM domain containing 4B
chr12_+_4300607 1.371 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr8_-_42184350 1.369 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr11_-_117640407 1.368 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr6_-_30289092 1.357 NM_003449
TRIM26
tripartite motif containing 26
chr17_-_45427565 1.357 NM_005220
DLX3
distal-less homeobox 3
chr1_+_112740322 1.352 NM_018704
CTTNBP2NL
CTTNBP2 N-terminal like
chr2_-_192767494 1.348 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_-_78710698 1.347 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr4_+_46728051 1.344 NM_000812
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr1_+_66570363 1.338 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_58631190 1.321 NM_001142703
NM_001142704
NM_198947
FAM111B


family with sequence similarity 111, member B


chr3_-_147361626 1.319 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr19_-_20540380 1.317 NM_001159293
ZNF737
zinc finger protein 737
chr6_-_166960690 1.314 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr9_-_35062545 1.310 VCP
valosin containing protein
chr20_+_43874654 1.308 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr5_+_102229612 1.303 PAM
peptidylglycine alpha-amidating monooxygenase
chr1_+_112740380 1.299 LOC100129406
CTTNBP2NL
hypothetical protein LOC100129406
CTTNBP2 N-terminal like
chr10_-_123346148 1.293 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr12_+_77782648 1.291 SYT1
synaptotagmin I
chr2_-_192767844 1.290 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr7_+_65307816 1.285 TPST1
tyrosylprotein sulfotransferase 1
chr8_-_78074851 1.285 NM_000318
NM_001079867
PEX2

peroxisomal biogenesis factor 2

chr6_-_26125939 1.281 NM_005325
HIST1H1A
histone cluster 1, H1a
chr9_-_20612433 1.281 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_93382735 1.278 PPP1R3C
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chrX_-_131451675 1.277 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chrX_-_62891730 1.267 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chrX_-_62891667 1.253 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr6_+_32970477 1.241 LOC100294145
hypothetical LOC100294145
chr4_-_5761194 1.234 NM_147127
EVC2
Ellis van Creveld syndrome 2
chr19_-_47619992 1.231 LIPE
lipase, hormone-sensitive
chr22_-_35502059 1.231 NM_001177701
NM_006860
IFT27

intraflagellar transport 27 homolog (Chlamydomonas)

chr9_+_136673464 1.230 NM_000093
COL5A1
collagen, type V, alpha 1
chrX_-_33139349 1.218 NM_004006
DMD
dystrophin
chr10_-_93382779 1.213 PPP1R3C
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chrX_+_53095230 1.211 NM_018969
GPR173
G protein-coupled receptor 173
chr17_+_65677255 1.210 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr5_-_112658200 1.209 MCC
mutated in colorectal cancers
chr7_-_93357881 1.203 NM_006528
TFPI2
tissue factor pathway inhibitor 2
chr11_-_127897271 1.196 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chrX_-_62891712 1.189 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr10_-_93382837 1.189 NM_005398
PPP1R3C
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr1_-_93919789 1.181 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chrX_+_135058402 1.181 NM_001159700
FHL1
four and a half LIM domains 1
chr3_+_50248678 1.176 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr7_-_42243142 1.175 NM_000168
GLI3
GLI family zinc finger 3
chr7_-_133794404 1.173 NM_001628
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr5_-_92982927 1.170


chr8_-_28403652 1.169 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr13_+_35904408 1.167 NM_001111045
NM_003914
CCNA1

cyclin A1

chr8_+_102573837 1.167 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr7_-_42243318 1.163 GLI3
GLI family zinc finger 3
chr19_+_57648570 1.144 NM_001099694
ZNF578
zinc finger protein 578
chr15_-_97607108 1.143 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr5_-_20024050 1.142 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr17_+_19222319 1.137 NM_002749
NM_139034
MAPK7

mitogen-activated protein kinase 7

chr6_-_169395847 1.135 THBS2
thrombospondin 2
chr12_-_45759691 1.134 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chrX_-_103060777 1.115 LOC100128594
hypothetical LOC100128594
chr9_+_91115924 1.114 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr3_+_113060826 1.114 PHLDB2
pleckstrin homology-like domain, family B, member 2
chr19_+_20138991 1.110 NM_052852
ZNF486
zinc finger protein 486
chr4_+_15080586 1.110 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr16_+_67236730 1.104 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr5_+_102229425 1.103 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr22_+_31080871 1.102 NM_006604
RFPL3
ret finger protein-like 3
chr5_-_112658456 1.101 NM_002387
MCC
mutated in colorectal cancers
chr7_-_27120015 1.095 HOXA3
homeobox A3
chr11_+_122806196 1.090 LOC100128242
hypothetical LOC100128242
chr3_-_64186151 1.089 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr12_+_52733927 1.085 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr4_+_120167264 1.085 SYNPO2
synaptopodin 2
chr6_+_46205659 1.083 NM_014936
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr8_+_102574012 1.080 GRHL2
grainyhead-like 2 (Drosophila)
chr3_-_192063158 1.078 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr12_+_77782925 1.072 SYT1
synaptotagmin I
chr3_+_50248652 1.064 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr4_-_83938920 1.060 NM_001037582
NM_024906
SCD5

stearoyl-CoA desaturase 5

chr5_+_57914658 1.057 NM_138453
RAB3C
RAB3C, member RAS oncogene family
chr10_-_62002672 1.057 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_+_155884600 1.056 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr4_+_155884564 1.054 LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr5_+_15553539 1.053 FBXL7
F-box and leucine-rich repeat protein 7
chr1_+_32703225 1.050 NM_001145720
ZBTB8B
zinc finger and BTB domain containing 8B
chr16_+_67236699 1.047 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr1_+_101475149 1.043 S1PR1
sphingosine-1-phosphate receptor 1
chr20_+_19903778 1.042 RIN2
Ras and Rab interactor 2
chr7_+_29569978 1.042 PRR15
proline rich 15
chr2_+_162908869 1.037 GCA
grancalcin, EF-hand calcium binding protein
chr18_+_19706979 1.036 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr7_+_65307691 1.030 NM_003596
TPST1
tyrosylprotein sulfotransferase 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 4.39e-05 GO:0043229 intracellular organelle
1.10 6.97e-05 GO:0043226 organelle
1.17 7.15e-05 GO:0005634 nucleus
1.11 3.80e-04 GO:0043227 membrane-bounded organelle
1.11 3.81e-04 GO:0043231 intracellular membrane-bounded organelle
1.07 1.66e-03 GO:0005622 intracellular
1.07 2.26e-03 GO:0044424 intracellular part
1.39 4.16e-02 GO:0042995 cell projection

Nothing significant found in function category.