Motif ID: GFI1B.p2

Z-value: 3.369


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor



Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_197173159 9.094 LOC100131234
familial acute myelogenous leukemia related factor
chr4_+_15080586 8.595 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr2_-_142605010 8.028 LRP1B
low density lipoprotein receptor-related protein 1B
chr4_+_183302105 7.475 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr12_-_28016182 7.148 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr1_-_177378801 6.870 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr9_+_676640 6.491


chr2_-_189752575 5.931 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_+_218768423 5.453 MARK1
MAP/microtubule affinity-regulating kinase 1
chr15_-_81744469 5.383 NM_001717
BNC1
basonuclin 1
chrX_-_43717864 5.174 NM_000266
NDP
Norrie disease (pseudoglioma)
chr6_+_12398514 5.120 NM_001168319
NM_001955
EDN1

endothelin 1

chrX_-_10548458 5.106 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr5_-_59100091 4.989 PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_66160359 4.947 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_+_219180821 4.362 PLCD4
phospholipase C, delta 4
chr2_+_219180875 4.346 NM_032726
PLCD4
phospholipase C, delta 4
chr2_+_219180862 4.286 PLCD4
phospholipase C, delta 4
chr7_-_81910956 4.075 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chrX_+_17303727 3.846 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr3_-_159872960 3.678 NM_020169
LXN
latexin
chr1_+_101475149 3.591 S1PR1
sphingosine-1-phosphate receptor 1
chr1_+_66570683 3.495 PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_+_83954229 3.295 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr1_+_101474892 3.274 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr12_-_22378833 3.116 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr1_+_161305558 3.114 NM_001113381
RGS4
regulator of G-protein signaling 4
chr7_+_18515440 3.108 HDAC9
histone deacetylase 9
chr3_-_192063158 3.051 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr12_-_83954185 3.021 NM_001100917
TSPAN19
tetraspanin 19
chr7_+_18515488 3.005 HDAC9
histone deacetylase 9
chrX_+_17303798 2.941 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr7_-_81910740 2.770 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_135231518 2.766 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr18_+_53863865 2.696 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr8_+_67946290 2.688 NM_001136160
C8orf45
chromosome 8 open reading frame 45
chr15_+_60146467 2.674 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr2_+_61225710 2.650 NM_001143960
C2orf74
chromosome 2 open reading frame 74
chr10_-_91001542 2.638 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr14_-_36121536 2.608 NM_014360
NKX2-8
NK2 homeobox 8
chr18_-_33399997 2.581 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr10_-_91001531 2.574 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr14_+_20580224 2.542 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr10_-_91001496 2.518 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr11_-_40272239 2.510 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr11_-_35503720 2.435 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_+_66570363 2.430 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chrX_+_17303270 2.393 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_-_26125939 2.360 NM_005325
HIST1H1A
histone cluster 1, H1a
chr5_-_137099602 2.303 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr1_+_216585298 2.283 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr3_-_113842350 2.265 CCDC80
coiled-coil domain containing 80
chrX_+_17303458 2.248 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr14_+_95792299 2.232 NM_000710
BDKRB1
bradykinin receptor B1
chr2_+_98070026 2.176 NM_144992
VWA3B
von Willebrand factor A domain containing 3B
chr2_-_164300758 2.111 NM_018086
FIGN
fidgetin
chr1_+_162795538 2.094 PBX1
pre-B-cell leukemia homeobox 1
chr12_-_113328271 2.072 NM_181486
TBX5
T-box 5
chr6_-_138862271 2.055 NM_001144060
NHSL1
NHS-like 1
chr6_-_166960649 2.038 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_176695658 1.998 NM_014213
HOXD9
homeobox D9
chr4_-_23500706 1.926 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_+_218768146 1.917 MARK1
MAP/microtubule affinity-regulating kinase 1
chr13_-_85271329 1.857 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr6_-_161614962 1.849 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr2_-_113310796 1.848 NM_000576
IL1B
interleukin 1, beta
chr3_-_113842255 1.846 CCDC80
coiled-coil domain containing 80
chr3_-_150578023 1.805 TM4SF1
transmembrane 4 L six family member 1
chr8_-_19584373 1.783 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr13_-_47885248 1.765 LPAR6
lysophosphatidic acid receptor 6
chr6_-_138862273 1.719


chr7_-_27171600 1.716 HOXA9
homeobox A9
chr5_-_20024050 1.712 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr3_-_113842237 1.709 CCDC80
coiled-coil domain containing 80
chr3_-_64186151 1.693 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr8_+_26206648 1.688 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr7_-_27171673 1.683 NM_152739
HOXA9
homeobox A9
chr10_+_118177371 1.681 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr6_-_134540666 1.679 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr3_+_113200696 1.671 NM_001008273
TAGLN3
transgelin 3
chr5_-_22889487 1.642 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr12_+_55201854 1.642 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr17_+_71232370 1.617 NM_001005619
ITGB4
integrin, beta 4
chr3_-_152517204 1.611 NM_023915
GPR87
G protein-coupled receptor 87
chr17_+_67628763 1.594 SOX9
SRY (sex determining region Y)-box 9
chr3_-_113842553 1.593 CCDC80
coiled-coil domain containing 80
chr1_+_157246305 1.587 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr7_-_27171648 1.570 HOXA9
homeobox A9
chr1_+_161305188 1.547 NM_005613
RGS4
regulator of G-protein signaling 4
chr4_+_42094612 1.509 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr17_+_67628772 1.485 SOX9
SRY (sex determining region Y)-box 9
chr22_+_38903825 1.485 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr3_-_121295663 1.476 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta

chr5_+_102229425 1.472 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr1_-_116184846 1.461 NM_001111061
NHLH2
nescient helix loop helix 2
chr6_-_166960690 1.401 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_21373816 1.398 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr11_-_8849485 1.396 ST5
suppression of tumorigenicity 5
chr5_-_22889192 1.396 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr3_-_188936941 1.395 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr5_-_137099361 1.383 KLHL3
kelch-like 3 (Drosophila)
chr17_-_70901303 1.358 GRB2
growth factor receptor-bound protein 2
chr3_+_190372456 1.346 NM_198485
TPRG1
tumor protein p63 regulated 1
chr4_+_113958652 1.322 NM_001127493
ANK2
ankyrin 2, neuronal
chr1_-_68470585 1.322 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr4_+_120167264 1.289 SYNPO2
synaptopodin 2
chr1_+_154520693 1.283 NM_032323
TMEM79
transmembrane protein 79
chr12_-_14929991 1.265 NM_000900
NM_001190839
MGP

matrix Gla protein

chr17_-_67628523 1.258 FLJ37644
hypothetical LOC400618
chr2_-_113259441 1.230 NM_000575
IL1A
interleukin 1, alpha
chr6_-_152744143 1.230 SYNE1
spectrin repeat containing, nuclear envelope 1
chr13_-_77391525 1.225


chrX_+_100692071 1.203 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr9_-_90983501 1.197 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr17_+_56884560 1.194 TBX4
T-box 4
chr5_-_171643247 1.173 UBTD2
ubiquitin domain containing 2
chr11_-_117640407 1.173 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr9_-_27287106 1.153 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr6_-_74284522 1.151 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr18_+_19706979 1.137 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr2_+_166034402 1.097 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chrX_-_72351348 1.096 NAP1L2
nucleosome assembly protein 1-like 2
chr21_+_29439768 1.094 C21orf7
chromosome 21 open reading frame 7
chrX_-_72351392 1.085 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chr1_-_79244948 1.081 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr1_-_116185215 1.080 NM_005599
NHLH2
nescient helix loop helix 2
chr2_+_162908828 1.072 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr1_+_27062215 1.045 NM_006142
SFN
stratifin
chr1_+_107485071 1.034 NTNG1
netrin G1
chr11_-_117305277 1.026 NM_001077263
TMPRSS13
transmembrane protease, serine 13
chr4_+_86968069 1.023 ARHGAP24
Rho GTPase activating protein 24
chr5_-_146813343 1.007 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr3_+_115258348 1.006 QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr14_-_57834558 0.998 FLJ31306
hypothetical LOC379025
chr12_+_52960798 0.997 HNRNPA1L2
HNRNPA1
HNRNPA1P10
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
chr1_+_218768170 0.993 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr11_+_5667494 0.987 NM_006074
TRIM22
tripartite motif containing 22
chr9_+_136673464 0.986 NM_000093
COL5A1
collagen, type V, alpha 1
chr22_-_34564611 0.974 RPL41P5
ribosomal protein L41 pseudogene 5
chr18_+_30327341 0.969 DTNA
dystrobrevin, alpha
chr18_+_59295123 0.957 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr17_+_7753428 0.946 CHD3
chromodomain helicase DNA binding protein 3
chr2_+_66516196 0.944 MEIS1
Meis homeobox 1
chr18_+_27281729 0.935 NM_001944
DSG3
desmoglein 3
chr21_-_46473143 0.935 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr6_+_26333361 0.914 NM_003532
HIST1H3E
histone cluster 1, H3e
chr16_+_70117523 0.911 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr3_+_115040369 0.911 NM_017577
GRAMD1C
GRAM domain containing 1C
chr3_-_113842652 0.905 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chrX_-_21586337 0.902 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr18_+_30327243 0.897 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr21_-_46473113 0.884 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr2_+_28887203 0.865 NM_001142634
NM_182756
SPDYA

speedy homolog A (Xenopus laevis)

chr18_+_3402071 0.862 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr3_-_191522886 0.862 NM_021101
CLDN1
claudin 1
chr18_+_42780784 0.860 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr17_+_67628749 0.855 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr20_+_33223434 0.844 NM_006404
PROCR
protein C receptor, endothelial
chr9_-_90983195 0.837 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr2_-_133895795 0.833 NCKAP5
NCK-associated protein 5
chr5_-_111119846 0.829 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr2_-_53940571 0.827 NM_001164165
NM_006794
GPR75-ASB3
GPR75
GPR75-ASB3 read-through transcript
G protein-coupled receptor 75
chr4_+_166468266 0.823 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr7_+_28415495 0.820 LOC401317
hypothetical LOC401317
chr17_-_53849929 0.817 NM_017763
RNF43
ring finger protein 43
chrX_+_101862297 0.812 NM_001142524
NM_001142525
NM_001142526
NM_001142527
NM_001142528
NM_030639
BHLHB9





basic helix-loop-helix domain containing, class B, 9





chr1_-_17180659 0.804 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chrX_-_57953578 0.794 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr19_-_9276794 0.793 NM_198535
ZNF266
ZNF699
zinc finger protein 266
zinc finger protein 699
chr5_-_58607673 0.786 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_101292462 0.778 NM_178127
ANGPTL5
angiopoietin-like 5
chr18_+_45342398 0.771 NM_006033
LIPG
lipase, endothelial
chr6_+_26128656 0.761 NM_003529
HIST1H3A
histone cluster 1, H3a
chr8_-_93099040 0.758 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_219026661 0.739 NM_022746
MOSC1
MOCO sulphurase C-terminal domain containing 1
chr9_-_16860719 0.737 NM_017637
BNC2
basonuclin 2
chr11_+_57285809 0.735 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001331
CTNND1












catenin (cadherin-associated protein), delta 1












chr3_+_120904555 0.732 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr1_-_202402043 0.731 NM_000537
REN
renin
chr4_+_166097579 0.725 C4orf39
chromosome 4 open reading frame 39
chrX_+_46581368 0.723 RP2
retinitis pigmentosa 2 (X-linked recessive)
chr11_-_102100833 0.719 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr5_-_150264622 0.714 ZNF300
zinc finger protein 300
chr12_+_52960745 0.709 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chr2_+_162908869 0.693 GCA
grancalcin, EF-hand calcium binding protein
chr10_-_91001566 0.690 NM_000235
NM_001127605
LIPA

lipase A, lysosomal acid, cholesterol esterase

chr11_+_5667392 0.680 TRIM22
tripartite motif containing 22
chr1_+_152229861 0.680 NM_001030
RPS27
ribosomal protein S27
chr2_+_204440753 0.678 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr5_-_146869811 0.675 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr3_+_142587973 0.674


chr1_-_108032645 0.670 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr11_+_34599227 0.670 EHF
ets homologous factor
chrX_+_46581290 0.664 NM_006915
RP2
retinitis pigmentosa 2 (X-linked recessive)
chr11_-_117640196 0.653 MPZL2
myelin protein zero-like 2
chrX_+_146941222 0.652 FTH1P8
ferritin, heavy polypeptide 1 pseudogene 8
chrX_+_150653873 0.640 NM_005140
CNGA2
cyclic nucleotide gated channel alpha 2
chr11_-_71424614 0.636


chr2_+_207512522 0.630 NM_173077
CPO
carboxypeptidase O
chr4_+_77829634 0.625 SHROOM3
shroom family member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 3.34e-02 GO:0032501 multicellular organismal process

Nothing significant found in compartment category.

Nothing significant found in function category.