• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: GTF2I.p2

Z-value: 4.328

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_68470585	9.456	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr9_+_108665168	7.093	NM_021224	ZNF462	zinc finger protein 462
chr1_+_156229934	6.133		KIRREL	kin of IRRE like (Drosophila)
chr11_+_12355600	5.921	NM_018222	PARVA	parvin, alpha
chr12_-_113606322	5.904	NM_005996 NM_016569	TBX3	T-box 3
chr22_-_34566210	5.727		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_36531958	5.693	NM_020856	TSHZ3	teashirt zinc finger homeobox 3
chr4_-_16509446	5.593	NM_001130834 NM_001290	LDB2	LIM domain binding 2
chr4_-_16509354	5.558		LDB2	LIM domain binding 2
chr1_-_20684858	5.467		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr22_-_34566276	5.350		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_-_27697768	5.268	NM_001143807	BDNF	brain-derived neurotrophic factor
chr2_-_19421852	5.071	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr2_+_100802923	5.023	NM_002518	NPAS2	neuronal PAS domain protein 2
chr4_-_16509126	5.006		LDB2	LIM domain binding 2
chr1_-_20685314	4.916	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_+_202308814	4.842	NM_005686	SOX13	SRY (sex determining region Y)-box 13
chr16_-_63713382	4.726	NM_001797	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_-_63713485	4.616		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_-_63713466	4.575		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr2_+_36436316	4.531		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr7_-_78920806	4.376	NM_012301	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_177950658	4.352	NM_005429	VEGFC	vascular endothelial growth factor C
chr19_-_59676153	4.346	NM_145057	CDC42EP5	CDC42 effector protein (Rho GTPase binding) 5
chr9_-_16860719	4.331	NM_017637	BNC2	basonuclin 2
chr2_-_164300758	4.054	NM_018086	FIGN	fidgetin
chr5_+_135392482	4.052	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr1_-_212791188	3.976		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr10_+_20145350	3.961	NM_032812	PLXDC2	plexin domain containing 2
chrX_+_152413540	3.953	NM_001711	BGN	biglycan
chr21_-_27139143	3.951		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr21_-_27139563	3.905	NM_006988	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr8_-_89408832	3.891	NM_005941	MMP16	matrix metallopeptidase 16 (membrane-inserted)
chr9_+_138341752	3.847	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr9_+_8848130	3.762
chr3_-_64648703	3.732		ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr22_-_34566367	3.696	NM_001031695 NM_001082576 NM_001082577 NM_014309	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_+_85069217	3.643
chr20_+_13924263	3.540		MACROD2	MACRO domain containing 2
chr8_-_93184629	3.525	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_156229686	3.497	NM_018240	KIRREL	kin of IRRE like (Drosophila)
chr13_+_57103789	3.487	NM_001040429	PCDH17	protocadherin 17
chr9_-_16860664	3.476		BNC2	basonuclin 2
chr1_-_212791467	3.460		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr1_-_212791597	3.441	NM_005401	PTPN14	protein tyrosine phosphatase, non-receptor type 14
chrX_+_152413646	3.434		BGN	biglycan
chr4_-_158111995	3.414	NM_016205	PDGFC	platelet derived growth factor C
chr4_-_158111916	3.406		PDGFC	platelet derived growth factor C
chr13_+_57103944	3.399		PCDH17	protocadherin 17
chr22_-_35914200	3.375	NM_031910 NM_182486	C1QTNF6	C1q and tumor necrosis factor related protein 6
chr1_+_162795538	3.367		PBX1	pre-B-cell leukemia homeobox 1
chr11_+_129823667	3.364	NM_139055	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr12_+_6363482	3.337	NM_002342	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr6_-_153494076	3.310	NM_012419	RGS17	regulator of G-protein signaling 17
chr12_-_47468985	3.309	NM_020983	ADCY6	adenylate cyclase 6
chr2_-_227371698	3.290	NM_005544	IRS1	insulin receptor substrate 1
chr9_+_35528890	3.246		RUSC2	RUN and SH3 domain containing 2
chr10_-_33663777	3.222	NM_001024628 NM_001024629 NM_003873	NRP1	neuropilin 1
chr3_+_37878647	3.212	NM_001008392 NM_005808	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr20_+_13924014	3.201	NM_080676	MACROD2	MACRO domain containing 2
chr4_+_30331289	3.154		PCDH7	protocadherin 7
chr19_+_61798434	3.037	NM_021216	ZNF71	zinc finger protein 71
chr15_+_45796802	3.018		SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_+_135392624	2.962		TGFBI	transforming growth factor, beta-induced, 68kDa
chr14_-_26136799	2.933	NM_002515 NM_006489 NM_006491	NOVA1	neuro-oncological ventral antigen 1
chr8_-_122722674	2.893	NM_005328	HAS2	hyaluronan synthase 2
chr1_-_72521079	2.822
chr12_+_55201854	2.796	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr22_+_44277354	2.777	NM_001996 NM_006485 NM_006486 NM_006487	FBLN1	fibulin 1
chr4_-_158111504	2.769		PDGFC	platelet derived growth factor C
chr7_+_78920846	2.767		LOC100505881	hypothetical LOC100505881
chr6_+_1335067	2.738	NM_001452	FOXF2	forkhead box F2
chr15_-_59308708	2.736		RORA	RAR-related orphan receptor A
chr11_-_122571198	2.713	NM_024769	CLMP	CXADR-like membrane protein
chr13_-_32822759	2.688		STARD13	StAR-related lipid transfer (START) domain containing 13
chr17_+_58058774	2.652		MRC2	mannose receptor, C type 2
chr2_-_192767494	2.639		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_-_194844299	2.622		KCNT2	potassium channel, subfamily T, member 2
chr3_+_189354167	2.607	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr14_-_53493198	2.605	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr5_-_178704934	2.603		ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chrX_+_73557809	2.595	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr11_-_122571046	2.577		CLMP	CXADR-like membrane protein
chr7_+_29200636	2.569	NM_004067	CHN2	chimerin (chimaerin) 2
chr3_-_121652183	2.560	NM_007085	FSTL1	follistatin-like 1
chr12_-_105057940	2.550	NM_014840	NUAK1	NUAK family, SNF1-like kinase, 1
chr5_+_92944680	2.498	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr10_-_79067210	2.480		KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr7_-_27136876	2.449	NM_002141	HOXA4	homeobox A4
chr4_+_30330963	2.448	NM_001173523 NM_002589 NM_032456 NM_032457	PCDH7	protocadherin 7
chr1_-_72520735	2.439	NM_173808	NEGR1	neuronal growth regulator 1
chr3_-_193609531	2.438	NM_021032	FGF12	fibroblast growth factor 12
chr19_+_46416975	2.436		AXL	AXL receptor tyrosine kinase
chrX_-_54538591	2.435		FGD1	FYVE, RhoGEF and PH domain containing 1
chr14_-_53491019	2.410	NM_130851	BMP4	bone morphogenetic protein 4
chr7_-_32077504	2.407	NM_001191059 NM_005020	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr2_-_218551786	2.379		TNS1	tensin 1
chr8_+_27547379	2.378	NM_016240 NM_182826	SCARA3	scavenger receptor class A, member 3
chr7_+_33911636	2.310	NM_133468	BMPER	BMP binding endothelial regulator
chr9_+_35528628	2.301	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr7_-_27120015	2.296		HOXA3	homeobox A3
chr3_+_77171938	2.284	NM_002942	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr18_-_21184824	2.260
chr2_+_54536780	2.244	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr14_+_22375753	2.242		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr3_-_31997738	2.239		OSBPL10	oxysterol binding protein-like 10
chr9_+_117955890	2.237	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr8_+_97575317	2.233		SDC2	syndecan 2
chr17_+_58058479	2.229	NM_006039	MRC2	mannose receptor, C type 2
chr8_+_30361485	2.217	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr15_+_41597097	2.209	NM_002373	MAP1A	microtubule-associated protein 1A
chr1_+_208472817	2.193	NM_019605	SERTAD4	SERTA domain containing 4
chr3_+_112273464	2.193	NM_015480	PVRL3	poliovirus receptor-related 3
chr15_-_59308770	2.179	NM_134261	RORA	RAR-related orphan receptor A
chr2_-_165406564	2.173		COBLL1	COBL-like 1
chr6_-_75972473	2.161		COL12A1	collagen, type XII, alpha 1
chr14_+_22375632	2.148	NM_004995	MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr7_+_29200850	2.147		CHN2	chimerin (chimaerin) 2
chr14_+_22375747	2.138		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr1_+_15957832	2.138	NM_017556	FBLIM1	filamin binding LIM protein 1
chr4_-_122213018	2.131	NM_024574	C4orf31	chromosome 4 open reading frame 31
chr6_-_152999678	2.130	NM_033071	SYNE1	spectrin repeat containing, nuclear envelope 1
chr19_+_59061422	2.122	NM_001020820	MYADM	myeloid-associated differentiation marker
chr1_+_162795328	2.116	NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr14_+_22375656	2.116		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr15_-_49174107	2.112		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr4_+_61749540	2.101		LPHN3	latrophilin 3
chr10_-_126839546	2.100	NM_001083914	CTBP2	C-terminal binding protein 2
chr2_+_85834111	2.080	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr4_+_145786622	2.075	NM_022475	HHIP	hedgehog interacting protein
chr1_+_168898898	2.064		PRRX1	paired related homeobox 1
chr6_-_80713589	2.058	NM_022726	ELOVL4	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr10_-_105604942	2.036	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr9_-_112381593	2.036	NM_153366	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr3_-_162572441	2.031	NM_001040100	C3orf57	chromosome 3 open reading frame 57
chr19_+_43572679	2.013	NM_001039616 NM_001042522	SPRED3	sprouty-related, EVH1 domain containing 3
chr2_+_27155197	2.001		EMILIN1	elastin microfibril interfacer 1
chr18_+_44319365	1.984	NM_001142397 NM_014772	CTIF	CBP80/20-dependent translation initiation factor
chr16_+_56219802	1.982	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr6_+_45498354	1.975		RUNX2	runt-related transcription factor 2
chr5_-_146813343	1.948	NM_001387	DPYSL3	dihydropyrimidinase-like 3
chr19_-_54557450	1.943	NM_003598	TEAD2	TEA domain family member 2
chr14_-_60185659	1.941	NM_005982	SIX1	SIX homeobox 1
chr19_-_60573552	1.933	NM_000641	IL11	interleukin 11
chr3_-_197103848	1.928		TNK2	tyrosine kinase, non-receptor, 2
chr8_+_97575244	1.924		SDC2	syndecan 2
chr17_+_58058783	1.909		MRC2	mannose receptor, C type 2
chr22_-_34754343	1.908	NM_001082578 NM_001082579	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_56004366	1.905	NM_001039348 NM_001039349	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1
chr2_+_188864975	1.874		GULP1	GULP, engulfment adaptor PTB domain containing 1
chr1_+_221955876	1.870	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chrX_+_144707022	1.869	NM_001144003 NM_001144004 NM_001144005 NM_032539	SLITRK2	SLIT and NTRK-like family, member 2
chr8_+_97575196	1.867		SDC2	syndecan 2
chr11_+_124539814	1.851		PKNOX2	PBX/knotted 1 homeobox 2
chr3_+_121296290	1.847
chr8_+_27547303	1.835		SCARA3	scavenger receptor class A, member 3
chr8_+_97575052	1.834	NM_002998	SDC2	syndecan 2
chr11_+_124539768	1.828	NM_022062	PKNOX2	PBX/knotted 1 homeobox 2
chr5_-_59100194	1.827	NM_001197218	PDE4D	phosphodiesterase 4D, cAMP-specific
chr14_-_104507862	1.822		AHNAK2	AHNAK nucleoprotein 2
chr20_+_8997791	1.819		PLCB4	phospholipase C, beta 4
chr1_-_150232900	1.807		S100A10	S100 calcium binding protein A10
chr2_-_218575922	1.783		TNS1	tensin 1
chr3_-_115825742	1.780	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr4_-_122063118	1.774	NM_018699	PRDM5	PR domain containing 5
chr12_-_24606616	1.767	NM_152989	SOX5	SRY (sex determining region Y)-box 5
chr10_-_33663305	1.761		NRP1	neuropilin 1
chr12_+_6800950	1.756	NM_014449 NM_019858	GPR162	G protein-coupled receptor 162
chr8_-_97242119	1.755	NM_001001557	GDF6	growth differentiation factor 6
chr2_+_85213884	1.744	NM_031283	TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)
chr6_-_153000226	1.738	NM_182961	SYNE1	spectrin repeat containing, nuclear envelope 1
chr18_+_17076166	1.736	NM_001142966	GREB1L	growth regulation by estrogen in breast cancer-like
chr7_-_19123787	1.733	NM_000474	TWIST1	twist homolog 1 (Drosophila)
chr22_-_26527469	1.725	NM_002430	MN1	meningioma (disrupted in balanced translocation) 1
chr6_+_17390273	1.712	NM_001143941	RBM24	RNA binding motif protein 24
chr3_+_61522310	1.703		PTPRG	protein tyrosine phosphatase, receptor type, G
chr2_+_27154938	1.701	NM_007046	EMILIN1	elastin microfibril interfacer 1
chr5_-_38881636	1.693
chr7_-_100262971	1.692	NM_004444	EPHB4	EPH receptor B4
chr7_+_121300394	1.674	NM_002851	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr2_-_192767844	1.671	NM_016192	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_+_199884152	1.667		NAV1	neuron navigator 1
chr19_+_38979502	1.665	NM_001129994 NM_001129995 NM_024076	KCTD15	potassium channel tetramerisation domain containing 15
chr5_+_38881719	1.665	NM_003999	OSMR	oncostatin M receptor
chr5_+_38882017	1.663		OSMR	oncostatin M receptor
chr7_+_27191534	1.659		HOXA11-AS1	HOXA11 antisense RNA 1 (non-protein coding)
chr13_-_95094920	1.652	NM_014934 NM_198968	DZIP1	DAZ interacting protein 1
chr15_+_45797977	1.652	NM_020858 NM_024966 NM_153616 NM_153617 NM_153618 NM_153619	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr16_-_31390926	1.651
chr8_+_97575370	1.650		SDC2	syndecan 2
chr2_-_165186232	1.650		GRB14	growth factor receptor-bound protein 14
chr13_+_87122778	1.647	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr10_-_79067296	1.640		KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_-_59100091	1.635		PDE4D	phosphodiesterase 4D, cAMP-specific
chr12_+_51729239	1.633		TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr5_+_31229609	1.631		CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)
chrX_+_12066505	1.629	NM_014728	FRMPD4	FERM and PDZ domain containing 4
chr12_-_94708641	1.623	NM_021229	NTN4	netrin 4
chr5_+_38881716	1.620	NM_001168355	OSMR	oncostatin M receptor
chr4_+_184257337	1.619	NM_024949	WWC2	WW and C2 domain containing 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.34	1.52e-28	GO:0048731	system development
1.28	4.54e-28	GO:0032502	developmental process
1.30	1.92e-27	GO:0007275	multicellular organismal development
1.31	8.88e-27	GO:0048856	anatomical structure development
1.18	1.65e-25	GO:0050794	regulation of cellular process
1.16	1.35e-23	GO:0050789	regulation of biological process
1.15	1.36e-23	GO:0065007	biological regulation
1.44	6.16e-22	GO:0007399	nervous system development
1.43	1.39e-21	GO:0009653	anatomical structure morphogenesis
1.53	5.95e-19	GO:0022008	neurogenesis
1.34	2.48e-18	GO:0030154	cell differentiation
1.54	3.88e-18	GO:0048699	generation of neurons
1.33	5.63e-18	GO:0048869	cellular developmental process
1.08	2.73e-15	GO:0009987	cellular process
1.21	5.88e-15	GO:0023052	signaling
1.26	7.42e-15	GO:0048518	positive regulation of biological process
1.65	3.51e-14	GO:0031175	neuron projection development
1.56	5.19e-14	GO:0030030	cell projection organization
1.27	8.48e-14	GO:0048522	positive regulation of cellular process
1.63	1.75e-13	GO:0000904	cell morphogenesis involved in differentiation
1.33	1.79e-13	GO:0023051	regulation of signaling
1.57	1.89e-13	GO:0000902	cell morphogenesis
1.36	2.77e-13	GO:0009966	regulation of signal transduction
1.55	4.77e-13	GO:0032989	cellular component morphogenesis
1.65	8.12e-13	GO:0048812	neuron projection morphogenesis
1.21	2.15e-12	GO:0007165	signal transduction
1.21	2.53e-12	GO:0016043	cellular component organization
1.51	2.71e-12	GO:0030182	neuron differentiation
1.27	5.16e-12	GO:0048523	negative regulation of cellular process
1.26	8.00e-12	GO:0048519	negative regulation of biological process
1.59	9.79e-12	GO:0032990	cell part morphogenesis
1.20	1.01e-11	GO:0071840	cellular component organization or biogenesis
1.48	1.20e-11	GO:2000026	regulation of multicellular organismal development
1.58	1.42e-11	GO:0048858	cell projection morphogenesis
1.29	2.53e-11	GO:0048583	regulation of response to stimulus
1.62	2.86e-11	GO:0048667	cell morphogenesis involved in neuron differentiation
1.42	3.25e-11	GO:0050793	regulation of developmental process
1.63	4.74e-11	GO:0007409	axonogenesis
1.28	5.11e-11	GO:0048513	organ development
1.53	7.38e-11	GO:0048666	neuron development
1.41	9.32e-11	GO:0048468	cell development
1.15	1.92e-10	GO:0032501	multicellular organismal process
1.17	1.20e-09	GO:0051716	cellular response to stimulus
1.22	2.78e-09	GO:0071842	cellular component organization at cellular level
1.66	5.78e-09	GO:0060284	regulation of cell development
1.39	8.03e-09	GO:0040011	locomotion
1.32	9.46e-09	GO:0051239	regulation of multicellular organismal process
1.44	1.93e-08	GO:0045595	regulation of cell differentiation
1.34	2.05e-08	GO:0010646	regulation of cell communication
1.39	2.38e-08	GO:0051128	regulation of cellular component organization
1.20	2.91e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.38	3.48e-08	GO:0008219	cell death
1.37	7.19e-08	GO:0016265	death
1.51	1.03e-07	GO:0072358	cardiovascular system development
1.51	1.03e-07	GO:0072359	circulatory system development
1.34	2.26e-07	GO:0009605	response to external stimulus
1.34	2.51e-07	GO:0032879	regulation of localization
1.41	2.76e-07	GO:0009790	embryo development
1.59	3.40e-07	GO:0007411	axon guidance
1.32	5.45e-07	GO:0010941	regulation of cell death
1.61	5.47e-07	GO:0022603	regulation of anatomical structure morphogenesis
1.36	5.96e-07	GO:0009888	tissue development
1.50	7.24e-07	GO:0051094	positive regulation of developmental process
1.62	8.03e-07	GO:0001944	vasculature development
1.32	8.14e-07	GO:0043067	regulation of programmed cell death
1.46	9.90e-07	GO:0006935	chemotaxis
1.46	9.90e-07	GO:0042330	taxis
1.74	1.15e-06	GO:0045664	regulation of neuron differentiation
2.20	2.48e-06	GO:0022612	gland morphogenesis
1.31	3.50e-06	GO:0042981	regulation of apoptosis
1.39	4.08e-06	GO:0009719	response to endogenous stimulus
1.64	5.43e-06	GO:0050767	regulation of neurogenesis
1.60	6.12e-06	GO:0051960	regulation of nervous system development
1.37	6.25e-06	GO:0012501	programmed cell death
1.46	7.94e-06	GO:0048646	anatomical structure formation involved in morphogenesis
1.55	9.71e-06	GO:0001501	skeletal system development
1.36	1.35e-05	GO:0006915	apoptosis
1.39	2.05e-05	GO:0009725	response to hormone stimulus
1.57	2.84e-05	GO:0061061	muscle structure development
1.37	3.28e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.27	4.23e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.57	7.10e-05	GO:0001568	blood vessel development
2.77	7.15e-05	GO:0060688	regulation of morphogenesis of a branching structure
1.18	7.30e-05	GO:0042221	response to chemical stimulus
1.34	8.28e-05	GO:0051049	regulation of transport
1.45	9.36e-05	GO:0009968	negative regulation of signal transduction
2.09	9.45e-05	GO:2000027	regulation of organ morphogenesis
1.41	9.90e-05	GO:0007417	central nervous system development
1.13	1.03e-04	GO:0019222	regulation of metabolic process
1.29	1.08e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.26	1.50e-04	GO:0031325	positive regulation of cellular metabolic process
1.85	1.61e-04	GO:0035023	regulation of Rho protein signal transduction
1.14	1.64e-04	GO:0031323	regulation of cellular metabolic process
1.25	2.07e-04	GO:0009893	positive regulation of metabolic process
1.86	2.30e-04	GO:0048736	appendage development
1.86	2.30e-04	GO:0060173	limb development
1.14	2.76e-04	GO:0080090	regulation of primary metabolic process
1.37	3.07e-04	GO:0006928	cellular component movement
1.52	3.21e-04	GO:0040012	regulation of locomotion
1.87	3.28e-04	GO:0035107	appendage morphogenesis
1.87	3.28e-04	GO:0035108	limb morphogenesis
1.38	3.59e-04	GO:0023056	positive regulation of signaling
1.45	4.17e-04	GO:0051056	regulation of small GTPase mediated signal transduction
1.39	5.69e-04	GO:0048585	negative regulation of response to stimulus
1.38	6.84e-04	GO:0009967	positive regulation of signal transduction
1.14	7.46e-04	GO:0060255	regulation of macromolecule metabolic process
1.53	8.19e-04	GO:0030334	regulation of cell migration
1.30	8.24e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.53	8.88e-04	GO:2000145	regulation of cell motility
1.44	9.00e-04	GO:0048598	embryonic morphogenesis
1.33	9.36e-04	GO:0010628	positive regulation of gene expression
1.89	9.40e-04	GO:0030326	embryonic limb morphogenesis
1.89	9.40e-04	GO:0035113	embryonic appendage morphogenesis
1.47	9.50e-04	GO:0045597	positive regulation of cell differentiation
1.37	9.78e-04	GO:0010647	positive regulation of cell communication
1.54	9.94e-04	GO:0046578	regulation of Ras protein signal transduction
1.51	1.00e-03	GO:0035295	tube development
1.30	1.19e-03	GO:0016192	vesicle-mediated transport
1.27	1.31e-03	GO:0042127	regulation of cell proliferation
1.49	1.57e-03	GO:0051270	regulation of cellular component movement
1.30	1.83e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39	1.99e-03	GO:0023057	negative regulation of signaling
1.74	2.04e-03	GO:0010975	regulation of neuron projection development
1.36	2.05e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.36	2.05e-03	GO:0043068	positive regulation of programmed cell death
1.43	2.17e-03	GO:0007420	brain development
1.47	2.39e-03	GO:0051130	positive regulation of cellular component organization
1.82	2.58e-03	GO:0030323	respiratory tube development
1.55	2.98e-03	GO:0048514	blood vessel morphogenesis
1.35	3.01e-03	GO:0010942	positive regulation of cell death
1.51	3.34e-03	GO:0030036	actin cytoskeleton organization
1.31	3.47e-03	GO:0051254	positive regulation of RNA metabolic process
1.32	3.48e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.44	3.53e-03	GO:0003006	developmental process involved in reproduction
1.89	3.62e-03	GO:0030100	regulation of endocytosis
1.38	4.06e-03	GO:0010648	negative regulation of cell communication
1.18	4.09e-03	GO:0007166	cell surface receptor linked signaling pathway
1.32	4.35e-03	GO:0010629	negative regulation of gene expression
1.35	4.37e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.66	4.65e-03	GO:0001655	urogenital system development
1.35	5.37e-03	GO:0043065	positive regulation of apoptosis
1.81	5.71e-03	GO:0030324	lung development
1.21	6.21e-03	GO:0035556	intracellular signal transduction
1.18	6.89e-03	GO:0006464	protein modification process
1.31	7.26e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.77	7.46e-03	GO:0010720	positive regulation of cell development
1.20	8.04e-03	GO:0065009	regulation of molecular function
1.35	8.07e-03	GO:0007010	cytoskeleton organization
1.67	8.50e-03	GO:0060537	muscle tissue development
1.33	8.63e-03	GO:0051253	negative regulation of RNA metabolic process
1.89	9.88e-03	GO:0050679	positive regulation of epithelial cell proliferation
1.16	1.10e-02	GO:0065008	regulation of biological quality
1.65	1.14e-02	GO:0050678	regulation of epithelial cell proliferation
1.08	1.17e-02	GO:0050896	response to stimulus
1.31	1.22e-02	GO:0009887	organ morphogenesis
1.29	1.30e-02	GO:0019220	regulation of phosphate metabolic process
1.29	1.30e-02	GO:0051174	regulation of phosphorus metabolic process
1.27	1.39e-02	GO:0007267	cell-cell signaling
1.67	1.50e-02	GO:0022604	regulation of cell morphogenesis
1.44	1.61e-02	GO:0030029	actin filament-based process
1.61	1.68e-02	GO:0031344	regulation of cell projection organization
1.54	1.68e-02	GO:0048732	gland development
1.12	1.89e-02	GO:0051179	localization
1.70	1.92e-02	GO:0060541	respiratory system development
1.27	2.02e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.63	2.29e-02	GO:0060627	regulation of vesicle-mediated transport
1.45	2.31e-02	GO:0048545	response to steroid hormone stimulus
1.29	2.39e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.66	2.53e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.13	2.57e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.48	2.65e-02	GO:0051129	negative regulation of cellular component organization
1.28	2.82e-02	GO:0042325	regulation of phosphorylation
2.60	2.86e-02	GO:0002053	positive regulation of mesenchymal cell proliferation
1.64	2.91e-02	GO:0048705	skeletal system morphogenesis
1.25	2.94e-02	GO:0031328	positive regulation of cellular biosynthetic process
1.38	3.19e-02	GO:0009792	embryo development ending in birth or egg hatching
1.52	3.69e-02	GO:0007517	muscle organ development
1.22	3.84e-02	GO:0007154	cell communication
1.42	3.86e-02	GO:0048729	tissue morphogenesis
1.24	3.95e-02	GO:0010605	negative regulation of macromolecule metabolic process
2.92	3.95e-02	GO:0060445	branching involved in salivary gland morphogenesis
1.35	4.19e-02	GO:0016477	cell migration
1.51	4.28e-02	GO:0007548	sex differentiation
1.37	4.34e-02	GO:0043009	chordate embryonic development
1.39	4.49e-02	GO:0071495	cellular response to endogenous stimulus
1.20	4.59e-02	GO:0051641	cellular localization
1.95	4.66e-02	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.50	1.42e-11	GO:0030054	cell junction
1.10	3.14e-11	GO:0005737	cytoplasm
1.40	1.12e-10	GO:0042995	cell projection
1.60	1.21e-10	GO:0043005	neuron projection
1.56	2.77e-09	GO:0045202	synapse
1.22	4.07e-09	GO:0044459	plasma membrane part
1.56	1.43e-08	GO:0031012	extracellular matrix
1.25	1.83e-07	GO:0005856	cytoskeleton
1.79	1.70e-06	GO:0005912	adherens junction
1.71	6.79e-06	GO:0070161	anchoring junction
1.05	1.51e-05	GO:0044424	intracellular part
1.50	1.82e-05	GO:0005578	proteinaceous extracellular matrix
1.18	3.98e-05	GO:0005829	cytosol
1.84	4.26e-05	GO:0030055	cell-substrate junction
1.87	5.52e-05	GO:0005925	focal adhesion
1.05	6.86e-05	GO:0005622	intracellular
1.49	8.84e-05	GO:0044456	synapse part
1.60	1.18e-04	GO:0030425	dendrite
1.48	1.33e-04	GO:0015629	actin cytoskeleton
1.81	1.75e-04	GO:0005924	cell-substrate adherens junction
1.60	2.99e-04	GO:0031252	cell leading edge
1.25	4.31e-04	GO:0005794	Golgi apparatus
1.64	7.19e-04	GO:0045211	postsynaptic membrane
1.50	1.03e-03	GO:0016323	basolateral plasma membrane
1.26	1.76e-03	GO:0031982	vesicle
1.38	1.92e-03	GO:0009986	cell surface
1.30	2.75e-03	GO:0044431	Golgi apparatus part
1.87	3.18e-03	GO:0042383	sarcolemma
1.54	3.41e-03	GO:0030424	axon
1.26	3.71e-03	GO:0031988	membrane-bounded vesicle
1.21	5.95e-03	GO:0044421	extracellular region part
1.24	1.54e-02	GO:0031410	cytoplasmic vesicle
1.12	1.89e-02	GO:0043228	non-membrane-bounded organelle
1.12	1.89e-02	GO:0043232	intracellular non-membrane-bounded organelle
1.24	2.02e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.07	2.16e-02	GO:0044444	cytoplasmic part
1.75	2.21e-02	GO:0014069	postsynaptic density
1.09	3.52e-02	GO:0071944	cell periphery
1.48	4.47e-02	GO:0043025	neuronal cell body
1.09	4.74e-02	GO:0005886	plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	7.36e-24	GO:0005515	protein binding
1.07	5.52e-15	GO:0005488	binding
1.43	3.86e-07	GO:0008092	cytoskeletal protein binding
1.52	4.70e-06	GO:0003779	actin binding
2.03	8.33e-05	GO:0005089	Rho guanyl-nucleotide exchange factor activity
1.26	1.46e-04	GO:0030528	transcription regulator activity
1.32	1.60e-04	GO:0043565	sequence-specific DNA binding
1.38	7.62e-04	GO:0019904	protein domain specific binding
1.81	1.84e-03	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.24	2.62e-03	GO:0001071	nucleic acid binding transcription factor activity
1.24	2.62e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.41	4.16e-03	GO:0016563	transcription activator activity
1.22	5.52e-03	GO:0005102	receptor binding
1.25	1.16e-02	GO:0019899	enzyme binding
1.32	2.30e-02	GO:0008289	lipid binding
1.64	4.28e-02	GO:0019838	growth factor binding