Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 4.352


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I



Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_134114957 11.654 CALD1
caldesmon 1
chr9_-_23816062 11.296 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_+_134114912 10.742 CALD1
caldesmon 1
chr13_-_73605914 9.764 NM_007249
KLF12
Kruppel-like factor 12
chr6_+_12398514 9.021 NM_001168319
NM_001955
EDN1

endothelin 1

chr2_-_56266408 8.726 LOC100129434
hypothetical LOC100129434
chr15_+_45797977 8.568 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr5_-_111119846 8.429 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr8_-_108579270 8.108 NM_001146
ANGPT1
angiopoietin 1
chr9_+_108665168 8.066 NM_021224
ZNF462
zinc finger protein 462
chr9_+_18464090 7.960 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr1_-_197173159 7.959 LOC100131234
familial acute myelogenous leukemia related factor
chr7_-_27186400 7.937 NM_153715
HOXA10
homeobox A10
chr9_+_18464138 7.911 ADAMTSL1
ADAMTS-like 1
chr13_-_109757442 7.628 NM_001845
COL4A1
collagen, type IV, alpha 1
chr11_-_85107569 7.599 NM_206929
SYTL2
synaptotagmin-like 2
chr13_-_98428244 7.471 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr12_-_16649211 7.422 LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_21774624 7.293 FLJ22536
hypothetical locus LOC401237
chr6_-_56824672 7.207 DST
dystonin
chr2_-_162808123 7.113 NM_004460
FAP
fibroblast activation protein, alpha
chr4_-_138673078 6.945 NM_019035
PCDH18
protocadherin 18
chr1_+_81544432 6.814 LPHN2
latrophilin 2
chr12_+_13240983 6.595 EMP1
epithelial membrane protein 1
chr5_-_16989371 6.578 NM_012334
MYO10
myosin X
chr7_-_27171673 6.533 NM_152739
HOXA9
homeobox A9
chr12_+_13240987 6.464 EMP1
epithelial membrane protein 1
chr5_-_16989290 6.348 MYO10
myosin X
chr16_+_85169615 6.341 NM_005250
FOXL1
forkhead box L1
chr14_-_91483325 6.288 FBLN5
fibulin 5
chr3_+_174598937 6.229 NM_014932
NLGN1
neuroligin 1
chr14_+_85066265 6.168 FLRT2
fibronectin leucine rich transmembrane protein 2
chr3_-_55496370 6.166 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chrX_-_19598912 6.114 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr5_+_15553736 5.981 FBXL7
F-box and leucine-rich repeat protein 7
chr13_-_73606362 5.961 KLF12
Kruppel-like factor 12
chr14_+_76298693 5.924 VASH1
vasohibin 1
chr3_-_194118321 5.918 MB21D2
Mab-21 domain containing 2
chr14_+_85066207 5.869 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_85108030 5.852 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr8_-_72436519 5.847 EYA1
eyes absent homolog 1 (Drosophila)
chr21_-_27261276 5.713 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr12_-_24606616 5.670 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr5_-_44424423 5.640 NM_004465
FGF10
fibroblast growth factor 10
chr4_+_86918882 5.510 ARHGAP24
Rho GTPase activating protein 24
chr1_-_68470585 5.490 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr6_-_56824371 5.451 DST
dystonin
chr6_-_128883125 5.418 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr3_-_55496607 5.329 WNT5A
wingless-type MMTV integration site family, member 5A
chr8_-_6407882 5.324 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chrX_+_77889861 5.301 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr15_-_53996597 5.231 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr7_-_27108826 5.186 NM_006735
HOXA2
homeobox A2
chr7_-_83662152 5.152 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_112337199 5.044 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr21_-_31853160 5.021 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr3_+_148593911 5.011


chr15_+_47502666 4.996 NM_002009
FGF7
fibroblast growth factor 7
chr5_+_15553539 4.948 FBXL7
F-box and leucine-rich repeat protein 7
chr3_+_100840129 4.910 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr4_-_101658094 4.905 NM_001159694
NM_016242
EMCN

endomucin

chr3_-_115825742 4.900 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_101488380 4.886 NM_001195045
YAP1
Yes-associated protein 1
chr8_-_93144366 4.872 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_16717887 4.866 BNC2
basonuclin 2
chr3_-_145049853 4.851 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr7_-_41709191 4.760 NM_002192
INHBA
inhibin, beta A
chr8_+_70567634 4.743 SULF1
sulfatase 1
chrX_-_99778340 4.725 NM_003270
TSPAN6
tetraspanin 6
chr5_+_15553288 4.671 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr8_+_70567581 4.568 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr7_+_28692122 4.491 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr11_+_131285747 4.415 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr2_-_164300758 4.413 NM_018086
FIGN
fidgetin
chr14_-_91483757 4.404 NM_006329
FBLN5
fibulin 5
chr5_-_83715947 4.388 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr11_+_131286513 4.362 NTM
neurotrimin
chrX_-_10548458 4.311 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr8_-_93144039 4.248


chr5_-_83716346 4.237 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr6_+_148705421 4.237 NM_015278
SASH1
SAM and SH3 domain containing 1
chr7_-_27171600 4.226 HOXA9
homeobox A9
chr4_-_111777651 4.201 PITX2
paired-like homeodomain 2
chr12_-_88270375 4.133 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr7_-_27171648 4.105 HOXA9
homeobox A9
chr8_-_29262240 4.087 NM_057158
DUSP4
dual specificity phosphatase 4
chr2_+_69093641 4.046 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr3_-_150533948 4.001 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr5_+_98132898 3.996 NM_001012761
RGMB
RGM domain family, member B
chr5_-_83052606 3.984 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr6_+_114285209 3.964 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chrX_-_62891066 3.963 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_-_207738858 3.959 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_+_123501186 3.947 DAB2IP
DAB2 interacting protein
chr6_-_94185780 3.915 NM_004440
EPHA7
EPH receptor A7
chr4_+_146623405 3.875 NM_001003688
SMAD1
SMAD family member 1
chr14_+_76297885 3.849 NM_014909
VASH1
vasohibin 1
chr9_-_14303509 3.849 NFIB
nuclear factor I/B
chr7_+_102340579 3.710 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr5_-_146813343 3.707 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr13_-_47885018 3.702 LPAR6
lysophosphatidic acid receptor 6
chr3_-_65999548 3.674 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr12_+_83954229 3.672 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr11_+_112337491 3.664 NCAM1
neural cell adhesion molecule 1
chr2_+_33213111 3.623 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr3_+_62280435 3.611 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr3_-_194118627 3.611 NM_178496
MB21D2
Mab-21 domain containing 2
chr2_+_12775814 3.610


chrX_+_28515479 3.597 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr4_-_138673014 3.568 PCDH18
protocadherin 18
chr12_+_13240868 3.561 NM_001423
EMP1
epithelial membrane protein 1
chr2_-_151052391 3.545 NM_005168
RND3
Rho family GTPase 3
chr1_-_238842071 3.545 NM_022469
GREM2
gremlin 2
chr8_-_72437020 3.540 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr4_+_183302105 3.537 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr1_+_161305188 3.476 NM_005613
RGS4
regulator of G-protein signaling 4
chr9_-_72673753 3.476 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr9_+_102380156 3.458 NM_001018116
MURC
muscle-related coiled-coil protein
chr7_-_27153892 3.447 NM_024014
HOXA6
homeobox A6
chr6_+_148705817 3.445 SASH1
SAM and SH3 domain containing 1
chr1_-_224993498 3.439 NM_002221
ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chrX_-_33139349 3.404 NM_004006
DMD
dystrophin
chrX_+_86659370 3.402 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr3_-_113841967 3.388 CCDC80
coiled-coil domain containing 80
chr8_+_67201684 3.367 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr9_+_117955890 3.342 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chrX_+_100220491 3.330 NM_021637
TMEM35
transmembrane protein 35
chr7_-_11838260 3.314 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr12_-_83954185 3.303 NM_001100917
TSPAN19
tetraspanin 19
chr1_-_191422346 3.294 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr14_+_22375753 3.241 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr18_-_29412148 3.240


chr14_+_22375747 3.231 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr10_-_62002672 3.221 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_116272911 3.219 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr4_+_119174947 3.194 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr2_-_188021117 3.189 NM_005795
CALCRL
calcitonin receptor-like
chr2_-_133144094 3.185 LYPD1
LY6/PLAUR domain containing 1
chr7_-_27149750 3.182 NM_019102
HOXA5
homeobox A5
chr9_+_27099138 3.180 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr9_-_4289915 3.175 GLIS3
GLIS family zinc finger 3
chr8_-_72436832 3.166 EYA1
eyes absent homolog 1 (Drosophila)
chr3_-_113842133 3.149 CCDC80
coiled-coil domain containing 80
chr13_-_47885248 3.141 LPAR6
lysophosphatidic acid receptor 6
chr5_+_15553768 3.140 FBXL7
F-box and leucine-rich repeat protein 7
chr3_+_114414064 3.084 NM_033254
BOC
Boc homolog (mouse)
chr12_-_16650687 3.064 LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_29297806 3.050 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr6_-_134680888 3.048 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr11_+_112337299 3.026 NCAM1
neural cell adhesion molecule 1
chrX_-_50573759 3.017 NM_020717
SHROOM4
shroom family member 4
chr7_+_134114701 3.005 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr18_+_7936885 3.000 PTPRM
protein tyrosine phosphatase, receptor type, M
chr8_-_70908130 2.976 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_+_75343352 2.962 PLAU
plasminogen activator, urokinase
chr12_-_16650697 2.961 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_+_20337249 2.952 NM_002214
ITGB8
integrin, beta 8
chr7_+_27190688 2.948


chr6_+_148705646 2.947 SASH1
SAM and SH3 domain containing 1
chr5_+_36642424 2.943 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_47588160 2.928 TNS3
tensin 3
chr11_+_128069203 2.921 FLI1
Friend leukemia virus integration 1
chr13_+_109757593 2.911 NM_001846
COL4A2
collagen, type IV, alpha 2
chr4_+_86918870 2.904 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr4_-_111777584 2.864 PITX2
paired-like homeodomain 2
chr1_-_95165089 2.851 NM_001839
CNN3
calponin 3, acidic
chr10_+_104525877 2.850 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr3_-_113842237 2.831 CCDC80
coiled-coil domain containing 80
chr3_-_129023850 2.824 NM_007283
MGLL
monoglyceride lipase
chr3_-_113842255 2.822 CCDC80
coiled-coil domain containing 80
chr3_-_11585264 2.808 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr15_+_22751162 2.803 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr1_+_162795538 2.793 PBX1
pre-B-cell leukemia homeobox 1
chr8_-_124622434 2.782 NM_058229
FBXO32
F-box protein 32
chr1_-_85703198 2.780 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_-_19123765 2.758 TWIST1
twist homolog 1 (Drosophila)
chr19_-_45016587 2.754 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chr11_+_128069183 2.738 FLI1
Friend leukemia virus integration 1
chr12_-_8706533 2.725 MFAP5
microfibrillar associated protein 5
chr17_-_46479127 2.722 SPAG9
sperm associated antigen 9
chr9_-_14303899 2.710 NFIB
nuclear factor I/B
chr6_+_136214495 2.708 NM_018945
PDE7B
phosphodiesterase 7B
chr1_-_50661716 2.703 NM_032110
DMRTA2
DMRT-like family A2
chr1_-_177378801 2.692 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr7_-_19123787 2.684 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr11_+_36354110 2.667 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr11_+_128069165 2.653 FLI1
Friend leukemia virus integration 1
chr10_+_71232281 2.639 COL13A1
collagen, type XIII, alpha 1
chr7_-_47588266 2.624 TNS3
tensin 3
chr7_+_93388951 2.609 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr21_-_38792173 2.602 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr11_-_78829342 2.600 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr6_+_130381408 2.593 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr1_-_85816520 2.588 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_-_152999678 2.552 NM_033071
SYNE1
spectrin repeat containing, nuclear envelope 1
chr17_-_76985538 2.538


chr6_-_75972473 2.538 COL12A1
collagen, type XII, alpha 1
chr22_-_34566210 2.537 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_-_27190882 2.533 HOXA11
homeobox A11
chr11_+_112337411 2.531 NCAM1
neural cell adhesion molecule 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.61e-17 GO:0032502 developmental process
1.31 2.69e-17 GO:0032501 multicellular organismal process
1.41 8.61e-17 GO:0007275 multicellular organismal development
1.45 5.30e-16 GO:0048731 system development
1.42 6.52e-16 GO:0048856 anatomical structure development
1.59 1.42e-12 GO:0009653 anatomical structure morphogenesis
1.59 2.07e-12 GO:0007399 nervous system development
1.47 1.16e-11 GO:0048869 cellular developmental process
1.48 1.20e-11 GO:0030154 cell differentiation
1.69 2.22e-09 GO:0022008 neurogenesis
1.70 4.94e-09 GO:0048699 generation of neurons
1.73 1.10e-07 GO:0030182 neuron differentiation
1.74 5.08e-07 GO:0032989 cellular component morphogenesis
1.62 7.98e-07 GO:0040011 locomotion
1.75 9.62e-07 GO:0000902 cell morphogenesis
1.77 1.30e-06 GO:0048666 neuron development
1.81 2.04e-06 GO:0000904 cell morphogenesis involved in differentiation
1.89 2.09e-06 GO:0007409 axonogenesis
1.65 2.23e-06 GO:0007155 cell adhesion
1.65 2.23e-06 GO:0022610 biological adhesion
1.86 3.08e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.85 3.71e-06 GO:0048812 neuron projection morphogenesis
1.80 4.79e-06 GO:0031175 neuron projection development
1.82 4.96e-06 GO:0072358 cardiovascular system development
1.82 4.96e-06 GO:0072359 circulatory system development
1.57 5.44e-06 GO:0048468 cell development
1.68 7.16e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 9.36e-06 GO:0048513 organ development
3.02 9.68e-06 GO:0051271 negative regulation of cellular component movement
1.76 1.49e-05 GO:0048858 cell projection morphogenesis
1.67 1.92e-05 GO:0030030 cell projection organization
1.64 2.01e-05 GO:0009790 embryo development
2.02 2.19e-05 GO:0001944 vasculature development
3.05 2.25e-05 GO:0030336 negative regulation of cell migration
3.05 2.25e-05 GO:2000146 negative regulation of cell motility
1.75 2.44e-05 GO:0032990 cell part morphogenesis
1.61 2.44e-05 GO:2000026 regulation of multicellular organismal development
1.94 4.97e-05 GO:0001501 skeletal system development
1.73 4.99e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.01 8.23e-05 GO:0001568 blood vessel development
2.01 1.54e-04 GO:0030334 regulation of cell migration
2.87 1.90e-04 GO:0048706 embryonic skeletal system development
1.40 1.98e-04 GO:0009966 regulation of signal transduction
1.98 2.51e-04 GO:2000145 regulation of cell motility
1.92 3.41e-04 GO:0051270 regulation of cellular component movement
2.70 3.66e-04 GO:0040013 negative regulation of locomotion
1.91 4.59e-04 GO:0030029 actin filament-based process
1.36 5.03e-04 GO:0023051 regulation of signaling
2.54 5.04e-04 GO:0048736 appendage development
2.54 5.04e-04 GO:0060173 limb development
1.79 5.89e-04 GO:0048598 embryonic morphogenesis
2.56 6.03e-04 GO:0035107 appendage morphogenesis
2.56 6.03e-04 GO:0035108 limb morphogenesis
1.88 6.50e-04 GO:0016337 cell-cell adhesion
1.90 6.70e-04 GO:0040012 regulation of locomotion
2.33 7.89e-04 GO:0007156 homophilic cell adhesion
1.97 1.18e-03 GO:0003002 regionalization
1.47 1.69e-03 GO:0050793 regulation of developmental process
2.32 1.87e-03 GO:0048705 skeletal system morphogenesis
1.54 2.13e-03 GO:0045595 regulation of cell differentiation
1.71 2.14e-03 GO:0016477 cell migration
2.00 2.16e-03 GO:0048514 blood vessel morphogenesis
1.79 2.81e-03 GO:0007411 axon guidance
1.32 2.95e-03 GO:0003008 system process
1.91 3.19e-03 GO:0030036 actin cytoskeleton organization
2.14 3.81e-03 GO:0009952 anterior/posterior pattern formation
1.26 3.99e-03 GO:0048519 negative regulation of biological process
2.03 4.19e-03 GO:0043408 regulation of MAPKKK cascade
1.76 4.19e-03 GO:0007389 pattern specification process
1.28 4.37e-03 GO:0048523 negative regulation of cellular process
1.84 4.54e-03 GO:0061061 muscle structure development
1.26 4.85e-03 GO:0048522 positive regulation of cellular process
1.56 4.98e-03 GO:0009887 organ morphogenesis
1.64 5.65e-03 GO:0048870 cell motility
1.64 5.65e-03 GO:0051674 localization of cell
1.14 5.90e-03 GO:0050896 response to stimulus
1.24 6.10e-03 GO:0048518 positive regulation of biological process
1.21 6.34e-03 GO:0007165 signal transduction
1.59 9.52e-03 GO:0007417 central nervous system development
1.20 9.54e-03 GO:0016043 cellular component organization
1.76 1.01e-02 GO:0060284 regulation of cell development
1.19 1.20e-02 GO:0023052 signaling
1.64 1.22e-02 GO:0007608 sensory perception of smell
1.29 1.24e-02 GO:0048583 regulation of response to stimulus
1.61 1.28e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.55 1.61e-02 GO:0006928 cellular component movement
2.83 1.63e-02 GO:0048704 embryonic skeletal system morphogenesis
1.35 1.82e-02 GO:0051239 regulation of multicellular organismal process
1.43 1.91e-02 GO:0009888 tissue development
1.44 2.59e-02 GO:0051128 regulation of cellular component organization
1.66 2.96e-02 GO:0009792 embryo development ending in birth or egg hatching
1.50 3.02e-02 GO:0045893 positive regulation of transcription, DNA-dependent
3.00 3.11e-02 GO:0010594 regulation of endothelial cell migration
1.45 3.15e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.12 3.17e-02 GO:0050794 regulation of cellular process
1.19 3.33e-02 GO:0071840 cellular component organization or biogenesis
3.36 3.46e-02 GO:0001952 regulation of cell-matrix adhesion
2.80 3.46e-02 GO:0016202 regulation of striated muscle tissue development
1.65 3.67e-02 GO:0043009 chordate embryonic development
2.38 3.70e-02 GO:0030326 embryonic limb morphogenesis
2.38 3.70e-02 GO:0035113 embryonic appendage morphogenesis
1.70 4.10e-02 GO:0051093 negative regulation of developmental process
2.75 4.70e-02 GO:0010810 regulation of cell-substrate adhesion
1.37 4.71e-02 GO:0010646 regulation of cell communication

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 2.84e-09 GO:0005886 plasma membrane
1.26 5.36e-09 GO:0071944 cell periphery
1.78 1.43e-08 GO:0030054 cell junction
2.00 4.33e-07 GO:0005578 proteinaceous extracellular matrix
1.87 2.53e-06 GO:0031012 extracellular matrix
2.42 2.58e-06 GO:0005912 adherens junction
2.68 3.54e-06 GO:0030055 cell-substrate junction
2.69 1.32e-05 GO:0005925 focal adhesion
2.23 2.91e-05 GO:0070161 anchoring junction
2.56 5.24e-05 GO:0005924 cell-substrate adherens junction
2.70 1.19e-04 GO:0030027 lamellipodium
2.01 9.95e-04 GO:0031252 cell leading edge
1.88 1.06e-03 GO:0016323 basolateral plasma membrane
1.66 1.08e-03 GO:0045202 synapse
1.32 1.10e-03 GO:0005856 cytoskeleton
2.29 1.40e-03 GO:0044420 extracellular matrix part
3.56 1.92e-03 GO:0042641 actomyosin
1.41 3.51e-03 GO:0042995 cell projection
1.24 6.94e-03 GO:0044459 plasma membrane part
7.83 1.56e-02 GO:0071437 invadopodium
3.36 3.61e-02 GO:0001725 stress fiber
2.02 4.85e-02 GO:0030016 myofibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.98 7.60e-07 GO:0003779 actin binding
1.73 1.98e-06 GO:0008092 cytoskeletal protein binding
1.41 1.78e-03 GO:0001071 nucleic acid binding transcription factor activity
1.41 1.78e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.49 2.91e-03 GO:0043565 sequence-specific DNA binding
1.64 5.41e-03 GO:0004984 olfactory receptor activity
2.57 5.70e-03 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.11 1.07e-02 GO:0005515 protein binding
2.42 1.29e-02 GO:0019199 transmembrane receptor protein kinase activity
1.44 2.92e-02 GO:0005509 calcium ion binding
4.40 3.51e-02 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
4.40 3.51e-02 GO:0019198 transmembrane receptor protein phosphatase activity
2.24 3.93e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.34 4.16e-02 GO:0030528 transcription regulator activity