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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HIC1.p2

Z-value: 6.195

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_109757442	13.036	NM_001845	COL4A1	collagen, type IV, alpha 1
chr13_+_109757593	12.839	NM_001846	COL4A2	collagen, type IV, alpha 2
chr11_+_101485946	11.597	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr2_-_112907577	11.047	NM_001164463	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr2_+_9532087	9.343	NM_001039613	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr8_+_32525269	9.085	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr1_-_48235148	8.999	NM_001194986	LOC388630	UPF0632 protein A
chr15_-_49174107	8.606		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr2_+_238200922	8.223	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr9_-_135847106	8.157	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr7_-_81910956	7.185	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr16_-_79395379	7.076	NM_152342	CDYL2	chromodomain protein, Y-like 2
chr4_-_141896920	6.922	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr9_+_123501186	6.896		DAB2IP	DAB2 interacting protein
chr9_-_21549696	6.890		LOC554202	hypothetical LOC554202
chr5_+_92946348	6.857		NR2F1	nuclear receptor subfamily 2, group F, member 1
chr6_+_147871477	6.729	NM_001030060	SAMD5	sterile alpha motif domain containing 5
chr9_+_115958051	6.699	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr2_+_238060602	6.694	NM_001042467 NM_024101	MLPH	melanophilin
chr15_+_99237527	6.645	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr13_-_43259032	6.624	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr9_+_17568952	6.605	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr14_+_92049396	6.556	NM_024832	RIN3	Ras and Rab interactor 3
chr20_+_8997660	6.531	NM_001172646	PLCB4	phospholipase C, beta 4
chr2_-_224612177	6.495	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_+_128583984	6.426	NM_001380	DOCK1	dedicator of cytokinesis 1
chr2_+_29191711	6.293	NM_024692	CLIP4	CAP-GLY domain containing linker protein family, member 4
chr14_+_85069217	6.288
chr13_-_100866839	6.279		NALCN	sodium leak channel, non-selective
chr3_+_61522310	6.273		PTPRG	protein tyrosine phosphatase, receptor type, G
chr10_+_116843108	6.133	NM_207303	ATRNL1	attractin-like 1
chr1_+_208472817	6.101	NM_019605	SERTAD4	SERTA domain containing 4
chr4_-_177950658	6.066	NM_005429	VEGFC	vascular endothelial growth factor C
chr10_+_71232281	6.035		COL13A1	collagen, type XIII, alpha 1
chr15_+_66658626	6.031	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr20_-_17459973	5.997	NM_001195	BFSP1	beaded filament structural protein 1, filensin
chr2_+_109112428	5.985	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr2_+_235525355	5.969	NM_014521	SH3BP4	SH3-domain binding protein 4
chr18_+_7557313	5.909	NM_001105244 NM_002845	PTPRM	protein tyrosine phosphatase, receptor type, M
chr12_-_41269679	5.903	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr17_+_52026058	5.900	NM_005450	NOG	noggin
chr13_-_100866706	5.883	NM_052867	NALCN	sodium leak channel, non-selective
chr12_+_20413445	5.849	NM_000921	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr4_+_95898098	5.834	NM_001203	BMPR1B	bone morphogenetic protein receptor, type IB
chr13_-_39075304	5.822		LHFP	lipoma HMGIC fusion partner
chrX_+_9943793	5.815	NM_015691	WWC3	WWC family member 3
chr17_-_74432671	5.790		TIMP2	TIMP metallopeptidase inhibitor 2
chr12_-_94708477	5.750		NTN4	netrin 4
chr1_+_17738863	5.681	NM_018125	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_-_85703198	5.667		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr13_+_97593711	5.662		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_-_98919109	5.627	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr7_-_27136876	5.577	NM_002141	HOXA4	homeobox A4
chr18_-_24011349	5.452	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr10_-_118022707	5.399	NM_001145453	GFRA1	GDNF family receptor alpha 1
chr18_-_42590989	5.391	NM_013305	ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr2_-_165406173	5.368	NM_014900	COBLL1	COBL-like 1
chr12_-_29827952	5.350	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr20_+_8997791	5.303		PLCB4	phospholipase C, beta 4
chr2_-_175255717	5.301	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr15_-_81744469	5.298	NM_001717	BNC1	basonuclin 1
chr1_-_95165089	5.253	NM_001839	CNN3	calponin 3, acidic
chr2_-_160972606	5.235		RBMS1	RNA binding motif, single stranded interacting protein 1
chr11_-_44928803	5.200	NM_001076787 NM_006034	TP53I11	tumor protein p53 inducible protein 11
chr18_+_29412538	5.191	NM_030632	ASXL3	additional sex combs like 3 (Drosophila)
chr6_+_72055197	5.159	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr7_-_81910740	5.140		CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr18_-_68361742	5.139		CBLN2	cerebellin 2 precursor
chr6_-_170441493	5.135	NM_005618	DLL1	delta-like 1 (Drosophila)
chr7_-_29995809	5.128	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr14_+_105012106	5.116	NM_001312	CRIP2	cysteine-rich protein 2
chr5_-_58370693	5.075	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr2_+_23461802	5.048	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr3_+_11171213	5.032	NM_001098212	HRH1	histamine receptor H1
chr7_-_32077504	5.018	NM_001191059 NM_005020	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr7_+_55054416	4.998		EGFR	epidermal growth factor receptor
chr3_+_53504070	4.985	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr22_+_47263919	4.962	NM_001082967	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr8_-_41286088	4.956	NM_003012	SFRP1	secreted frizzled-related protein 1
chr7_-_32076985	4.955	NM_001191056 NM_001191057	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr2_+_54537842	4.951		SPTBN1	spectrin, beta, non-erythrocytic 1
chr4_+_19864332	4.924	NM_004787	SLIT2	slit homolog 2 (Drosophila)
chr3_+_61522219	4.922	NM_002841	PTPRG	protein tyrosine phosphatase, receptor type, G
chr6_-_153494076	4.920	NM_012419	RGS17	regulator of G-protein signaling 17
chr10_+_124211353	4.920		HTRA1	HtrA serine peptidase 1
chr2_+_100802923	4.919	NM_002518	NPAS2	neuronal PAS domain protein 2
chr17_+_26322168	4.897		RNF135	ring finger protein 135
chr7_+_55054152	4.883	NM_005228 NM_201282 NM_201283 NM_201284	EGFR	epidermal growth factor receptor
chr6_+_3696224	4.858
chr4_-_122063118	4.832	NM_018699	PRDM5	PR domain containing 5
chr6_+_1556543	4.765		FOXC1	forkhead box C1
chr4_-_24523605	4.764	NM_001130726	CCDC149	coiled-coil domain containing 149
chr6_+_72055229	4.744		OGFRL1	opioid growth factor receptor-like 1
chr19_+_38377329	4.741	NM_002333	LRP3	low density lipoprotein receptor-related protein 3
chr12_-_94708641	4.740	NM_021229	NTN4	netrin 4
chr13_-_39075355	4.735	NM_005780	LHFP	lipoma HMGIC fusion partner
chr16_+_85158357	4.727	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr14_+_104402626	4.725	NM_001112726 NM_015005	KIAA0284	KIAA0284
chr14_+_58174489	4.698	NM_001079520 NM_016651	DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
chr1_-_95165037	4.681		CNN3	calponin 3, acidic
chr1_-_8008934	4.676		ERRFI1	ERBB receptor feedback inhibitor 1
chr6_+_170441715	4.674		FAM120B	family with sequence similarity 120B
chr17_+_8865547	4.669	NM_004822	NTN1	netrin 1
chr5_+_178419938	4.666	NM_014594	ZNF354C	zinc finger protein 354C
chr21_+_45318861	4.630	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr6_-_105691235	4.589	NM_007073	BVES	blood vessel epicardial substance
chr6_+_72055235	4.558		OGFRL1	opioid growth factor receptor-like 1
chr2_-_96174502	4.556		DUSP2	dual specificity phosphatase 2
chr15_+_99237555	4.537		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr7_-_107883929	4.533	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr19_+_15079141	4.526	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr7_-_44331544	4.505	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr4_+_158216631	4.502	NM_000824 NM_001166061 NM_001166060	GLRB	glycine receptor, beta
chr14_+_95575319	4.475		C14orf132	chromosome 14 open reading frame 132
chr18_-_7107757	4.470	NM_005559	LAMA1	laminin, alpha 1
chr2_-_127580975	4.468	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr14_+_104226769	4.463	NM_001031714 NM_022489 NM_032714	INF2	inverted formin, FH2 and WH2 domain containing
chr10_+_124210980	4.453	NM_002775	HTRA1	HtrA serine peptidase 1
chr1_+_234372454	4.452	NM_003272	GPR137B	G protein-coupled receptor 137B
chr17_+_26322081	4.450	NM_001184992 NM_032322 NM_197939	RNF135	ring finger protein 135
chr2_+_120820140	4.441	NM_002193	INHBB	inhibin, beta B
chr1_-_56817568	4.381		PPAP2B	phosphatidic acid phosphatase type 2B
chr11_+_131285747	4.377	NM_001144058 NM_001144059 NM_016522	NTM	neurotrimin
chr18_-_24010944	4.360		CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr13_-_109236897	4.345	NM_003749	IRS2	insulin receptor substrate 2
chr18_+_65219114	4.342	NM_152721	DOK6	docking protein 6
chr2_-_235070431	4.340	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr12_-_78608154	4.338		PAWR	PRKC, apoptosis, WT1, regulator
chr13_+_95541093	4.336	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr22_-_41446740	4.310	NM_017436	A4GALT	alpha 1,4-galactosyltransferase
chr12_+_26003218	4.302	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr8_-_485330	4.288	NM_175075	C8orf42	chromosome 8 open reading frame 42
chr17_-_10042579	4.287	NM_201433	GAS7	growth arrest-specific 7
chr8_+_27547379	4.287	NM_016240 NM_182826	SCARA3	scavenger receptor class A, member 3
chr8_+_17398940	4.280	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr13_+_97593469	4.274		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr18_+_19523402	4.264		LAMA3	laminin, alpha 3
chr9_-_139060377	4.241		NPDC1	neural proliferation, differentiation and control, 1
chr18_+_19523526	4.230	NM_001127717 NM_198129	LAMA3	laminin, alpha 3
chr2_+_241586927	4.219	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr5_-_146869811	4.213	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chr22_-_19122047	4.207		SCARF2	scavenger receptor class F, member 2
chr10_-_128066935	4.204		ADAM12	ADAM metallopeptidase domain 12
chrX_+_73557809	4.180	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr8_+_38733913	4.175		TACC1	transforming, acidic coiled-coil containing protein 1
chr14_+_63389360	4.162	NM_015180 NM_182914	SYNE2	spectrin repeat containing, nuclear envelope 2
chr4_+_151218862	4.160	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr19_+_61742111	4.149	NM_020828	ZFP28	zinc finger protein 28 homolog (mouse)
chr7_+_288195	4.138		FAM20C	family with sequence similarity 20, member C
chr1_-_234294997	4.115		NID1	nidogen 1
chr12_-_62348506	4.106	NM_173812	DPY19L2	dpy-19-like 2 (C. elegans)
chr5_-_146869613	4.082		DPYSL3	dihydropyrimidinase-like 3
chr9_-_139060285	4.077		NPDC1	neural proliferation, differentiation and control, 1
chr6_-_105691675	4.069		BVES	blood vessel epicardial substance
chr9_-_71476917	4.056	NM_001163	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1
chr22_-_19122107	4.012	NM_153334 NM_182895	SCARF2	scavenger receptor class F, member 2
chr16_-_71639670	4.009	NM_006885	ZFHX3	zinc finger homeobox 3
chr8_-_125809559	3.989		MTSS1	metastasis suppressor 1
chr11_+_86189138	3.978	NM_007173	PRSS23	protease, serine, 23
chr12_+_3056781	3.968	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr16_-_52877467	3.962		IRX3	iroquois homeobox 3
chr4_+_156899575	3.940	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr20_+_56701224	3.939	NM_024663	NPEPL1	aminopeptidase-like 1
chr5_+_129268352	3.936	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr3_+_44878380	3.930	NM_144638	TMEM42	transmembrane protein 42
chr18_-_5620629	3.910		EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr10_+_133850325	3.906	NM_006426	DPYSL4	dihydropyrimidinase-like 4
chr5_-_16989371	3.899	NM_012334	MYO10	myosin X
chr13_-_39075200	3.898		LHFP	lipoma HMGIC fusion partner
chr14_+_54104099	3.892		SAMD4A	sterile alpha motif domain containing 4A
chr14_+_64240996	3.880		PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr15_+_77511912	3.880	NM_015206	KIAA1024	KIAA1024
chr14_+_64240902	3.850	NM_015549	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr7_+_288051	3.843	NM_020223	FAM20C	family with sequence similarity 20, member C
chr17_-_6400470	3.824	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr10_+_112247614	3.814	NM_004419	DUSP5	dual specificity phosphatase 5
chr9_+_131974506	3.807	NM_014286	NCS1	neuronal calcium sensor 1
chr20_-_4177519	3.799	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr5_-_16989290	3.796		MYO10	myosin X
chr3_+_128874458	3.752	NM_172027	ABTB1	ankyrin repeat and BTB (POZ) domain containing 1
chr11_-_8849485	3.752		ST5	suppression of tumorigenicity 5
chr18_-_29412148	3.740
chr7_+_79602023	3.738	NM_002069	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr2_-_165406098	3.736		COBLL1	COBL-like 1
chr4_+_77829634	3.726		SHROOM3	shroom family member 3
chr10_-_128067001	3.709		ADAM12	ADAM metallopeptidase domain 12
chrX_+_147389825	3.703	NM_001169122 NM_001169123 NM_001169124 NM_001169125 NM_002025	AFF2	AF4/FMR2 family, member 2
chr17_+_78303202	3.702	NM_005993	TBCD	tubulin folding cofactor D
chr20_+_59260847	3.697	NM_001794	CDH4	cadherin 4, type 1, R-cadherin (retinal)
chr12_+_66328760	3.690	NM_003583 NM_006482	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr14_-_29466562	3.680	NM_002742	PRKD1	protein kinase D1
chr3_+_141136691	3.680	NM_022131	CLSTN2	calsyntenin 2
chr5_-_171813960	3.674		SH3PXD2B	SH3 and PX domains 2B
chr10_-_118022965	3.658	NM_005264	GFRA1	GDNF family receptor alpha 1
chr10_-_30065760	3.652		SVIL	supervillin
chr1_-_223907283	3.645	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr20_-_55718351	3.641	NM_020182	PMEPA1	prostate transmembrane protein, androgen induced 1
chr1_+_213323182	3.638	NM_001017425 NM_014217	KCNK2	potassium channel, subfamily K, member 2
chr21_+_45649719	3.638
chr17_+_77780177	3.600	NM_004207	SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.47	1.52e-23	GO:0007399	nervous system development
1.59	1.43e-22	GO:0022008	neurogenesis
1.60	2.71e-21	GO:0048699	generation of neurons
1.36	1.55e-19	GO:0030154	cell differentiation
1.35	1.75e-19	GO:0048869	cellular developmental process
1.26	5.36e-19	GO:0007275	multicellular organismal development
1.41	1.86e-18	GO:0009653	anatomical structure morphogenesis
1.62	3.74e-18	GO:0030182	neuron differentiation
1.24	7.87e-18	GO:0032502	developmental process
1.39	1.02e-17	GO:0023051	regulation of signaling
1.15	1.40e-17	GO:0050794	regulation of cellular process
1.72	4.61e-17	GO:0000904	cell morphogenesis involved in differentiation
1.28	4.79e-17	GO:0048731	system development
1.76	1.24e-16	GO:0048667	cell morphogenesis involved in neuron differentiation
1.66	1.24e-16	GO:0048666	neuron development
1.64	2.60e-16	GO:0000902	cell morphogenesis
1.74	6.29e-16	GO:0048812	neuron projection morphogenesis
1.40	7.18e-16	GO:0009966	regulation of signal transduction
1.75	1.38e-15	GO:0007409	axonogenesis
1.50	1.38e-15	GO:0048468	cell development
1.25	2.77e-15	GO:0048856	anatomical structure development
1.67	4.03e-15	GO:0032990	cell part morphogenesis
1.68	4.26e-15	GO:0031175	neuron projection development
1.67	6.10e-15	GO:0048858	cell projection morphogenesis
1.59	6.73e-15	GO:0030030	cell projection organization
1.58	3.25e-14	GO:0032989	cellular component morphogenesis
1.08	3.34e-13	GO:0009987	cellular process
1.13	1.09e-12	GO:0050789	regulation of biological process
1.12	8.57e-12	GO:0065007	biological regulation
1.74	1.16e-11	GO:0007411	axon guidance
1.19	2.92e-09	GO:0007165	signal transduction
1.27	3.64e-09	GO:0048583	regulation of response to stimulus
1.25	3.88e-09	GO:0048523	negative regulation of cellular process
1.18	4.59e-09	GO:0023052	signaling
1.23	1.03e-08	GO:0048519	negative regulation of biological process
1.61	1.92e-08	GO:0051056	regulation of small GTPase mediated signal transduction
1.22	3.64e-08	GO:0048522	positive regulation of cellular process
1.31	3.74e-08	GO:0035556	intracellular signal transduction
1.35	5.08e-08	GO:0010646	regulation of cell communication
1.72	1.05e-07	GO:0046578	regulation of Ras protein signal transduction
1.46	1.10e-07	GO:0009887	organ morphogenesis
1.17	2.35e-07	GO:0031323	regulation of cellular metabolic process
1.43	2.98e-07	GO:0007167	enzyme linked receptor protein signaling pathway
1.36	3.16e-07	GO:0050793	regulation of developmental process
1.42	3.59e-07	GO:0045595	regulation of cell differentiation
1.39	6.00e-07	GO:2000026	regulation of multicellular organismal development
1.20	9.77e-07	GO:0071842	cellular component organization at cellular level
1.16	1.08e-06	GO:0080090	regulation of primary metabolic process
1.36	1.10e-06	GO:0040011	locomotion
1.49	1.25e-06	GO:0072358	cardiovascular system development
1.49	1.25e-06	GO:0072359	circulatory system development
1.59	1.77e-06	GO:0060284	regulation of cell development
1.19	3.02e-06	GO:0048518	positive regulation of biological process
1.45	7.56e-06	GO:0007417	central nervous system development
1.61	8.51e-06	GO:0035295	tube development
1.87	1.51e-05	GO:0030111	regulation of Wnt receptor signaling pathway
1.51	3.16e-05	GO:0048598	embryonic morphogenesis
1.17	3.17e-05	GO:0071841	cellular component organization or biogenesis at cellular level
1.96	3.21e-05	GO:0010720	positive regulation of cell development
1.26	3.89e-05	GO:0051239	regulation of multicellular organismal process
1.30	4.09e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.13	4.47e-05	GO:0051716	cellular response to stimulus
1.57	4.89e-05	GO:0001944	vasculature development
1.15	6.31e-05	GO:0016043	cellular component organization
1.42	6.55e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.42	7.94e-05	GO:0006935	chemotaxis
1.42	7.94e-05	GO:0042330	taxis
2.03	8.45e-05	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.53	8.63e-05	GO:0001501	skeletal system development
1.13	1.21e-04	GO:0019222	regulation of metabolic process
1.54	1.57e-04	GO:0048729	tissue morphogenesis
1.21	1.62e-04	GO:0007166	cell surface receptor linked signaling pathway
1.43	1.94e-04	GO:0051094	positive regulation of developmental process
1.15	2.05e-04	GO:0060255	regulation of macromolecule metabolic process
1.45	2.11e-04	GO:0009968	negative regulation of signal transduction
1.20	2.13e-04	GO:0048513	organ development
1.17	2.18e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42	2.59e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.16	3.20e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.43	4.00e-04	GO:0023057	negative regulation of signaling
1.51	4.40e-04	GO:0022603	regulation of anatomical structure morphogenesis
1.48	4.51e-04	GO:0007389	pattern specification process
1.30	4.72e-04	GO:0009888	tissue development
1.34	4.76e-04	GO:0009890	negative regulation of biosynthetic process
1.42	4.87e-04	GO:0010648	negative regulation of cell communication
1.49	5.00e-04	GO:0045597	positive regulation of cell differentiation
1.34	6.43e-04	GO:0051254	positive regulation of RNA metabolic process
1.39	7.78e-04	GO:0048585	negative regulation of response to stimulus
1.53	9.03e-04	GO:0001568	blood vessel development
1.55	9.77e-04	GO:0050767	regulation of neurogenesis
1.33	1.02e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.61	1.22e-03	GO:0045664	regulation of neuron differentiation
1.51	1.36e-03	GO:0051960	regulation of nervous system development
1.33	1.38e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.13	1.48e-03	GO:0071840	cellular component organization or biogenesis
1.39	1.68e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.34	1.87e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.26	2.12e-03	GO:0009605	response to external stimulus
1.56	2.27e-03	GO:0002009	morphogenesis of an epithelium
1.33	2.53e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.27	2.64e-03	GO:0042127	regulation of cell proliferation
1.62	2.79e-03	GO:0035239	tube morphogenesis
1.17	3.22e-03	GO:0051252	regulation of RNA metabolic process
1.55	4.34e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.32	4.61e-03	GO:0001932	regulation of protein phosphorylation
1.13	4.76e-03	GO:0051179	localization
1.29	4.92e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.31	5.03e-03	GO:0009790	embryo development
1.35	5.23e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.91	5.37e-03	GO:0050769	positive regulation of neurogenesis
1.31	5.94e-03	GO:0010628	positive regulation of gene expression
1.35	6.19e-03	GO:0051253	negative regulation of RNA metabolic process
1.33	6.28e-03	GO:0010629	negative regulation of gene expression
1.36	6.86e-03	GO:0007010	cytoskeleton organization
1.15	6.94e-03	GO:0031326	regulation of cellular biosynthetic process
1.15	7.07e-03	GO:0010468	regulation of gene expression
1.14	7.37e-03	GO:0009889	regulation of biosynthetic process
1.26	7.45e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.16	7.90e-03	GO:0006355	regulation of transcription, DNA-dependent
1.71	8.59e-03	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.30	8.78e-03	GO:0019220	regulation of phosphate metabolic process
1.30	8.78e-03	GO:0051174	regulation of phosphorus metabolic process
1.25	9.26e-03	GO:0009892	negative regulation of metabolic process
1.27	9.73e-03	GO:0051128	regulation of cellular component organization
1.28	1.15e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.93	1.18e-02	GO:0071901	negative regulation of protein serine/threonine kinase activity
1.27	1.19e-02	GO:0031399	regulation of protein modification process
1.69	1.21e-02	GO:0022604	regulation of cell morphogenesis
1.87	1.33e-02	GO:0060485	mesenchyme development
1.38	1.33e-02	GO:0008285	negative regulation of cell proliferation
1.68	1.37e-02	GO:0051348	negative regulation of transferase activity
1.30	1.37e-02	GO:0042325	regulation of phosphorylation
1.72	1.39e-02	GO:0006469	negative regulation of protein kinase activity
1.15	1.56e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.06	1.57e-02	GO:0043407	negative regulation of MAP kinase activity
1.39	1.67e-02	GO:0007264	small GTPase mediated signal transduction
1.64	1.75e-02	GO:0001655	urogenital system development
1.64	1.75e-02	GO:0016311	dephosphorylation
1.74	1.81e-02	GO:0072001	renal system development
1.69	1.82e-02	GO:0033673	negative regulation of kinase activity
1.17	1.88e-02	GO:0006464	protein modification process
1.25	2.04e-02	GO:0031324	negative regulation of cellular metabolic process
1.72	2.10e-02	GO:0035023	regulation of Rho protein signal transduction
1.61	2.33e-02	GO:0048562	embryonic organ morphogenesis
1.67	2.33e-02	GO:0048705	skeletal system morphogenesis
1.88	2.43e-02	GO:0016331	morphogenesis of embryonic epithelium
1.30	2.66e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.74	2.74e-02	GO:0001822	kidney development
1.85	3.07e-02	GO:0021953	central nervous system neuron differentiation
1.97	3.12e-02	GO:0072175	epithelial tube formation
1.37	3.41e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.30	4.14e-02	GO:0042060	wound healing
1.64	4.38e-02	GO:0006470	protein dephosphorylation
1.34	4.45e-02	GO:0045859	regulation of protein kinase activity
1.29	4.56e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.50	4.65e-02	GO:0048514	blood vessel morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	1.72e-14	GO:0044424	intracellular part
1.08	2.47e-14	GO:0005622	intracellular
1.10	3.78e-10	GO:0005737	cytoplasm
1.07	4.53e-07	GO:0043226	organelle
1.07	6.11e-07	GO:0043229	intracellular organelle
1.39	5.10e-06	GO:0030054	cell junction
1.10	9.36e-06	GO:0044444	cytoplasmic part
1.46	9.79e-06	GO:0045202	synapse
1.07	1.44e-05	GO:0043227	membrane-bounded organelle
1.75	1.84e-05	GO:0005912	adherens junction
1.07	1.89e-05	GO:0043231	intracellular membrane-bounded organelle
1.70	2.20e-05	GO:0070161	anchoring junction
1.63	1.55e-04	GO:0031252	cell leading edge
1.26	3.24e-04	GO:0005794	Golgi apparatus
1.03	6.41e-04	GO:0044464	cell part
1.03	6.86e-04	GO:0005623	cell
1.15	4.50e-03	GO:0005829	cytosol
1.15	4.52e-03	GO:0044459	plasma membrane part
1.08	5.83e-03	GO:0005634	nucleus
1.72	8.09e-03	GO:0005925	focal adhesion
1.40	1.15e-02	GO:0044456	synapse part
1.74	2.43e-02	GO:0030027	lamellipodium
1.64	2.77e-02	GO:0030055	cell-substrate junction
1.64	4.18e-02	GO:0005924	cell-substrate adherens junction
1.48	4.56e-02	GO:0044297	cell body

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.60	1.42e-11	GO:0030695	GTPase regulator activity
1.58	4.12e-11	GO:0060589	nucleoside-triphosphatase regulator activity
1.60	8.09e-07	GO:0005083	small GTPase regulator activity
1.05	3.97e-06	GO:0005488	binding
1.30	4.15e-06	GO:0030528	transcription regulator activity
1.30	4.31e-06	GO:0001071	nucleic acid binding transcription factor activity
1.30	4.31e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.40	1.16e-05	GO:0008092	cytoskeletal protein binding
1.47	2.31e-04	GO:0003779	actin binding
1.53	2.47e-04	GO:0005096	GTPase activator activity
1.40	2.58e-04	GO:0019904	protein domain specific binding
1.66	4.57e-04	GO:0004721	phosphoprotein phosphatase activity
1.41	7.16e-04	GO:0008047	enzyme activator activity
1.08	8.71e-04	GO:0005515	protein binding
1.25	1.36e-03	GO:0030234	enzyme regulator activity
1.62	2.33e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.42	2.78e-03	GO:0042578	phosphoric ester hydrolase activity
1.48	3.86e-03	GO:0016791	phosphatase activity
1.11	5.04e-03	GO:0046872	metal ion binding
1.28	6.71e-03	GO:0043565	sequence-specific DNA binding
1.69	7.54e-03	GO:0051020	GTPase binding
1.10	1.34e-02	GO:0043169	cation binding
1.76	1.47e-02	GO:0017016	Ras GTPase binding
1.10	1.52e-02	GO:0043167	ion binding
1.50	1.54e-02	GO:0000975	regulatory region DNA binding
1.50	1.54e-02	GO:0001067	regulatory region nucleic acid binding
1.50	1.54e-02	GO:0044212	transcription regulatory region DNA binding
1.49	3.24e-02	GO:0010843	promoter binding
1.81	3.57e-02	GO:0005089	Rho guanyl-nucleotide exchange factor activity