Motif ID: HOXA9_MEIS1.p2

Z-value: 1.674


Transcription factors associated with HOXA9_MEIS1.p2:

Gene SymbolEntrez IDGene Name
HOXA9 3205 homeobox A9
MEIS1 4211 Meis homeobox 1



Activity profile for motif HOXA9_MEIS1.p2.

activity profile for motif HOXA9_MEIS1.p2


Sorted Z-values histogram for motif HOXA9_MEIS1.p2

Sorted Z-values for motif HOXA9_MEIS1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA9_MEIS1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_9875722 4.306 NM_001098529
NM_032243
TXNDC2

thioredoxin domain containing 2 (spermatozoa)

chr16_+_29597965 3.691 QPRT
quinolinate phosphoribosyltransferase
chr4_-_40211324 3.571 RBM47
RNA binding motif protein 47
chr9_-_99740243 2.617 NM_197978
HEMGN
hemogen
chr1_+_196874839 2.617 PTPRC
protein tyrosine phosphatase, receptor type, C
chr15_+_42815851 2.597 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr16_+_29597829 2.273 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr1_-_611896 2.218 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr1_+_144152864 1.920 TXNIP
thioredoxin interacting protein
chrX_-_130792297 1.861 LOC286467
hypothetical LOC286467
chr6_-_25044156 1.823 FAM65B
family with sequence similarity 65, member B
chr15_-_56093477 1.744 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_+_357502 1.672 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr19_+_61624 1.671 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr8_-_107023 1.589 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr12_-_107551783 1.587 NM_003006
SELPLG
selectin P ligand
chrX_-_131181141 1.444 RAP2C
RAP2C, member of RAS oncogene family
chr1_+_196874867 1.425 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_169631777 1.401 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_-_49708279 1.376 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_58899 1.318 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr10_-_76488277 1.298 NM_001003892
DUPD1
dual specificity phosphatase and pro isomerase domain containing 1
chr1_+_196874759 1.291 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_-_157313179 1.233 NM_004833
AIM2
absent in melanoma 2
chr2_+_68445821 1.209 NM_002664
PLEK
pleckstrin
chr12_+_7348194 1.134 NM_001080454
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr3_+_153468518 1.131 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr3_-_173723754 1.117 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr7_+_115650240 1.114 NM_152829
TES
testis derived transcript (3 LIM domains)
chr12_-_107551694 1.080 SELPLG
selectin P ligand
chr2_-_144994349 1.028 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr10_+_70517823 1.020 NM_002727
SRGN
serglycin
chr4_+_47403107 1.007


chr1_-_200397300 1.003 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr15_-_100280784 0.966 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr3_-_139960874 0.959 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr18_+_18989786 0.918 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr4_+_123311207 0.914 NM_015312
KIAA1109
KIAA1109
chr6_-_49712483 0.897 NM_000324
RHAG
Rh-associated glycoprotein
chr12_-_107551744 0.762 SELPLG
selectin P ligand
chr2_+_68445936 0.752 PLEK
pleckstrin
chr17_-_35464414 0.752 NM_001079518
NM_014815
MED24

mediator complex subunit 24

chr6_+_29382381 0.722 NM_030946
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr19_+_44681443 0.711 DLL3
delta-like 3 (Drosophila)
chr22_-_25205376 0.693 NM_152841
HPS4
Hermansky-Pudlak syndrome 4
chr11_-_62145952 0.689 NM_012200
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr10_-_75071498 0.686 NM_021245
MYOZ1
myozenin 1
chr1_-_153477511 0.675 GBA
glucosidase, beta, acid
chr22_+_21393107 0.626 IGLJ3
immunoglobulin lambda joining 3
chr1_-_167822248 0.625 F5
coagulation factor V (proaccelerin, labile factor)
chr8_-_13018123 0.609 NM_001164271
DLC1
deleted in liver cancer 1
chr12_-_101115677 0.608 NM_002674
PMCH
pro-melanin-concentrating hormone
chr11_-_4675524 0.606 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr17_+_38247493 0.581 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr18_+_70317548 0.572 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr5_+_128328685 0.565 SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr1_-_148854503 0.561


chr7_+_72883128 0.556 NM_001305
CLDN4
claudin 4
chr19_+_44681374 0.555 NM_016941
NM_203486
DLL3

delta-like 3 (Drosophila)

chr2_-_135498716 0.552 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr3_-_191650291 0.552 NM_207316
TMEM207
transmembrane protein 207
chr6_-_29451042 0.549 NM_030959
OR12D3
olfactory receptor, family 12, subfamily D, member 3
chr4_+_39084867 0.548 NM_175737
KLB
klotho beta
chr19_-_15451203 0.530 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr7_-_143560850 0.529 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr5_+_180726874 0.511 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr19_-_3723208 0.510 NM_032753
RAX2
retina and anterior neural fold homeobox 2
chr15_+_64481270 0.505 MAP2K1
mitogen-activated protein kinase kinase 1
chr11_-_16387001 0.505 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr1_+_938709 0.486 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr1_+_67404756 0.477 NM_144701
IL23R
interleukin 23 receptor
chr6_+_31782618 0.476 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr6_+_28032997 0.447 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr5_-_134290789 0.445


chr7_+_143457083 0.445 NM_001001659
OR2A14
olfactory receptor, family 2, subfamily A, member 14
chr15_-_23204887 0.444 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr10_+_70517863 0.444 SRGN
serglycin
chr1_-_109651140 0.443 NM_001010985
MYBPHL
myosin binding protein H-like
chr9_-_124280025 0.442 NM_001004451
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr15_-_41346346 0.442 NM_004245
NM_201631
TGM5

transglutaminase 5

chr21_-_46849413 0.439 NM_006272
S100B
S100 calcium binding protein B
chr21_+_39745649 0.437 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr20_-_60435983 0.434 NM_080833
C20orf151
chromosome 20 open reading frame 151
chr7_+_104468614 0.432 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr1_+_13903936 0.431 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr3_+_123279439 0.424 NM_006889
CD86
CD86 molecule
chr15_-_74091817 0.418 NM_138573
NRG4
neuregulin 4
chrX_-_102870207 0.410 NM_001024452
NM_001172285
GLRA4

glycine receptor, alpha 4

chr1_-_167822334 0.407 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr9_+_129951552 0.398 NM_005564
LCN2
lipocalin 2
chr4_+_159351092 0.397 TMEM144
transmembrane protein 144
chr11_+_56862395 0.395 NM_002559
P2RX3
purinergic receptor P2X, ligand-gated ion channel, 3
chr6_-_159386007 0.395 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr1_-_245237977 0.394 NM_020394
ZNF695
zinc finger protein 695
chr1_-_245237925 0.391 ZNF695
zinc finger protein 695
chr7_+_26644014 0.381 NM_001145531
C7orf71
chromosome 7 open reading frame 71
chr11_+_73339011 0.378 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr3_+_82117978 0.377


chr2_-_37269193 0.367 NM_001032377
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr6_-_32665409 0.366 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr18_-_29882555 0.363 NM_001198549
NOL4
nucleolar protein 4
chr6_-_11219932 0.359 NM_207582
ERVFRDE1
HERV-FRD provirus ancestral Env polyprotein
chr4_+_71713324 0.358 NM_031889
ENAM
enamelin
chrX_-_77469635 0.347 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr4_+_39084936 0.346 KLB
klotho beta
chr6_+_125346208 0.343 NM_152553
RNF217
ring finger protein 217
chr3_+_112743729 0.340 CD96
CD96 molecule
chr21_-_33107813 0.339 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr1_-_246525502 0.334 NM_001004692
OR2T12
olfactory receptor, family 2, subfamily T, member 12
chr17_+_53587492 0.332 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr14_+_77939845 0.331 NM_004796
NRXN3
neurexin 3
chr5_-_142795269 0.331 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr16_-_24850163 0.328 ARHGAP17
Rho GTPase activating protein 17
chr6_+_73133152 0.326 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr10_+_35524835 0.319 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr12_-_21439637 0.318 NM_134431
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr19_+_44681425 0.315 DLL3
delta-like 3 (Drosophila)
chr7_-_112515068 0.310 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr9_+_95886558 0.307 NM_152422
PTPDC1
protein tyrosine phosphatase domain containing 1
chr9_+_95886625 0.303 PTPDC1
protein tyrosine phosphatase domain containing 1
chr19_-_14085979 0.303 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr1_+_224079597 0.300 NM_000120
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr17_-_39094787 0.295 NM_001040002
MEOX1
mesenchyme homeobox 1
chr20_+_29931257 0.292 TTLL9
tubulin tyrosine ligase-like family, member 9
chr2_-_74634569 0.290 NM_032603
LOXL3
lysyl oxidase-like 3
chr12_-_10453409 0.280 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chrX_+_123062143 0.279 STAG2
stromal antigen 2
chr20_+_5935897 0.276 NM_001127458
CRLS1
cardiolipin synthase 1
chr1_-_153477673 0.275 NM_001171812
NM_000157
GBA

glucosidase, beta, acid

chr12_+_61645361 0.272 RPL14
ribosomal protein L14
chr7_+_143646150 0.265 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr21_-_44836811 0.263 NM_198688
KRTAP10-6
keratin associated protein 10-6
chr7_-_84589182 0.261 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr11_-_8921155 0.259 NM_020646
ASCL3
achaete-scute complex homolog 3 (Drosophila)
chrX_-_30505804 0.259 NM_025159
CXorf21
chromosome X open reading frame 21
chr8_-_102034370 0.251 NM_001135699
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr3_-_52544061 0.244 NM_022908
NT5DC2
5'-nucleotidase domain containing 2
chr2_+_61243132 0.240 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr6_+_70633168 0.239 NM_001858
COL19A1
collagen, type XIX, alpha 1
chr6_+_64414389 0.238 NM_015153
PHF3
PHD finger protein 3
chr18_+_70318001 0.238 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr15_+_70193652 0.235 NM_001166340
SENP8
SUMO/sentrin specific peptidase family member 8
chr21_+_44941514 0.233 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr6_-_27988152 0.232 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr6_+_32254108 0.227 NM_006913
RNF5
ring finger protein 5
chr3_+_112743615 0.227 NM_005816
NM_198196
CD96

CD96 molecule

chrX_+_119622570 0.225 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chrX_+_64625339 0.223 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr9_+_92629525 0.221 NM_001174167
SYK
spleen tyrosine kinase
chr12_-_52827275 0.219


chr1_-_57204208 0.217 NM_000066
C8B
complement component 8, beta polypeptide
chr11_-_111287657 0.215 NM_001885
CRYAB
crystallin, alpha B
chr12_-_51629874 0.209 KRT8
keratin 8
chr6_-_138581319 0.208 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr2_+_28678274 0.206 PLB1
phospholipase B1
chr18_-_27594696 0.203 NM_001034172
MCART2
mitochondrial carrier triple repeat 2
chr19_-_43926953 0.199 NM_144691
CAPN12
calpain 12
chr11_+_71387572 0.196 NM_001039659
NM_001039660
NM_173042
IL18BP


interleukin 18 binding protein


chr1_-_245237952 0.193 ZNF695
zinc finger protein 695
chrX_+_79562601 0.192 NM_152630
FAM46D
family with sequence similarity 46, member D
chr6_-_43054865 0.190 PEX6
peroxisomal biogenesis factor 6
chr8_-_27997306 0.189 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr3_+_99699137 0.189 NM_001004737
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr6_+_12622286 0.189


chr5_-_22889192 0.186 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr17_+_35471971 0.186 NM_001190919
THRA
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr17_-_44154878 0.185 NM_032391
PRAC
prostate cancer susceptibility candidate
chr18_-_50776276 0.184 NM_001143829
CCDC68
coiled-coil domain containing 68
chr12_+_53809731 0.182 NM_001005243
OR9K2
olfactory receptor, family 9, subfamily K, member 2
chr1_+_169747788 0.181 PRRC2C
proline-rich coiled-coil 2C
chr2_-_207291364 0.179 NM_001093730
DYTN
dystrotelin
chr1_+_109043550 0.175 PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr2_-_6924092 0.173 CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr5_-_176671897 0.173 NM_001142935
NM_031300
MXD3

MAX dimerization protein 3

chr6_-_25940247 0.172 NM_005074
SLC17A1
solute carrier family 17 (sodium phosphate), member 1
chr5_+_140730014 0.171 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr9_-_14076901 0.167 NFIB
nuclear factor I/B
chr4_-_56948345 0.165 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr20_-_33706532 0.164 RBM12
RNA binding motif protein 12
chr11_+_5862076 0.163 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr3_-_52839727 0.162 NM_001166449
NM_002218
ITIH4

inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)

chr7_+_44612645 0.161 NM_001003941
NM_001165036
NM_002541
OGDH


oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)


chr6_-_29163027 0.159 NM_001005226
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chr1_+_227506751 0.158 NM_006542
SPHAR
S-phase response (cyclin related)
chrX_-_15243647 0.155 NM_080873
ASB11
ankyrin repeat and SOCS box containing 11
chr12_-_51332214 0.149 NM_000423
KRT2
keratin 2
chr1_-_167865973 0.147 NM_003005
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr17_+_63338500 0.145 BPTF
bromodomain PHD finger transcription factor
chr10_+_80942362 0.143 NM_001099692
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr1_-_84099261 0.139


chr6_+_25760352 0.137 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr5_+_140583098 0.136 NM_018934
PCDHB14
protocadherin beta 14
chr7_+_90177082 0.135 CDK14
cyclin-dependent kinase 14
chr20_-_43641378 0.133 NM_130896
NM_181510
WFDC8

WAP four-disulfide core domain 8

chr1_+_151498802 0.132 NM_000427
LOR
loricrin
chr3_-_87408301 0.130 NM_000306
NM_001122757
POU1F1

POU class 1 homeobox 1

chr7_-_107230867 0.130 NM_000111
SLC26A3
solute carrier family 26, member 3
chr10_-_50402148 0.126 NM_170753
PGBD3
piggyBac transposable element derived 3
chr12_+_48310593 0.123 NM_001031698
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr6_-_43651578 0.123 XPO5
exportin 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.98 4.31e-06 GO:0007608 sensory perception of smell
3.70 9.29e-06 GO:0007606 sensory perception of chemical stimulus
2.62 5.61e-04 GO:0007600 sensory perception
1.93 5.93e-03 GO:0003008 system process
2.06 6.99e-03 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.42 2.33e-02 GO:0005886 plasma membrane
1.40 3.92e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.17 3.81e-07 GO:0004984 olfactory receptor activity
1.92 1.19e-03 GO:0004872 receptor activity
2.29 6.00e-03 GO:0004930 G-protein coupled receptor activity
1.98 8.20e-03 GO:0004888 transmembrane receptor activity