Motif ID: MAFB.p2

Z-value: 3.747


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)



Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_83329562 4.090 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr2_-_192767494 3.798 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr16_+_81218142 2.946 CDH13
cadherin 13, H-cadherin (heart)
chr10_-_79067476 2.936 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_+_81218074 2.830 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr9_-_109291575 2.811 KLF4
Kruppel-like factor 4 (gut)
chr11_-_35503720 2.779 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr12_+_52618815 2.734 NM_017410
HOXC13
homeobox C13
chr20_+_19903778 2.727 RIN2
Ras and Rab interactor 2
chr9_-_25668230 2.723 TUSC1
tumor suppressor candidate 1
chr8_+_32525269 2.664 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr4_+_61749540 2.617 LPHN3
latrophilin 3
chr8_-_89408832 2.599 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr6_+_45498262 2.568 RUNX2
runt-related transcription factor 2
chrX_+_51503219 2.529 NM_018094
GSPT2
G1 to S phase transition 2
chr15_-_37999519 2.517


chr14_+_85066265 2.474 FLRT2
fibronectin leucine rich transmembrane protein 2
chr10_-_79067210 2.444 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr13_-_25523164 2.425 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr6_+_45498354 2.414 RUNX2
runt-related transcription factor 2
chr3_-_185025989 2.406 NM_024871
MAP6D1
MAP6 domain containing 1
chr6_-_78229838 2.364 NM_000863
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr2_-_161058120 2.361 RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_-_69674412 2.343 FRMD4B
FERM domain containing 4B
chrX_-_34585287 2.316 NM_031442
TMEM47
transmembrane protein 47
chr1_+_64012154 2.297 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr20_-_22978141 2.278 NM_000361
THBD
thrombomodulin
chr14_+_85066207 2.263 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr10_+_52504239 2.252 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr4_-_111763655 2.245 NM_000325
PITX2
paired-like homeodomain 2
chr17_-_28644118 2.240 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr4_-_141293572 2.213 MAML3
mastermind-like 3 (Drosophila)
chr20_+_52525538 2.194 NM_018431
DOK5
docking protein 5
chr8_-_11096257 2.173 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr4_-_111763356 2.119 PITX2
paired-like homeodomain 2
chr5_+_17270474 2.106 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr13_-_76358370 2.103 KCTD12
potassium channel tetramerisation domain containing 12
chr5_+_42459568 2.084 NM_000163
GHR
growth hormone receptor
chr8_+_37672427 2.061 NM_025069
ZNF703
zinc finger protein 703
chr20_-_55718351 2.025 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr6_-_75972286 2.014 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr2_-_227371698 1.986 NM_005544
IRS1
insulin receptor substrate 1
chr10_+_59942874 1.962 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr5_+_140326237 1.959 PCDHAC2
protocadherin alpha subfamily C, 2
chr7_-_27149750 1.959 NM_019102
HOXA5
homeobox A5
chr9_-_84867604 1.947 RASEF
RAS and EF-hand domain containing
chr12_+_52665196 1.929 NM_017409
HOXC10
homeobox C10
chr7_-_19123765 1.915 TWIST1
twist homolog 1 (Drosophila)
chr5_-_146869811 1.896 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr3_+_112273352 1.895 PVRL3
poliovirus receptor-related 3
chr5_+_129268352 1.888 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr3_-_64186151 1.884 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr19_-_13478037 1.880 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr2_+_100802923 1.858 NM_002518
NPAS2
neuronal PAS domain protein 2
chr9_-_16717887 1.853 BNC2
basonuclin 2
chr7_-_19123787 1.849 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr9_-_112381593 1.848 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr3_+_148610516 1.843 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr15_-_37999717 1.841 GPR176
G protein-coupled receptor 176
chr11_+_131285747 1.835 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr5_+_66160359 1.834 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr15_+_72006015 1.832 LOXL1
lysyl oxidase-like 1
chr7_-_127458231 1.830 NM_022143
LRRC4
leucine rich repeat containing 4
chr16_+_85158357 1.823 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr5_-_146869613 1.822 DPYSL3
dihydropyrimidinase-like 3
chr8_-_108579270 1.820 NM_001146
ANGPT1
angiopoietin 1
chr11_-_1725924 1.815 NM_001170820
LOC402778
CD225 family protein FLJ76511
chr7_-_41709191 1.814 NM_002192
INHBA
inhibin, beta A
chrX_+_17303727 1.806 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr18_-_24010944 1.802 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr22_-_34566367 1.796 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr3_+_106568243 1.765 ALCAM
activated leukocyte cell adhesion molecule
chrX_+_17303798 1.754 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr5_+_174084137 1.745 NM_002449
MSX2
msh homeobox 2
chr22_-_34566276 1.744 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_66772393 1.744 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_-_78920806 1.738 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_109290107 1.734 KLF4
Kruppel-like factor 4 (gut)
chr15_-_46724360 1.730 FBN1
fibrillin 1
chr5_-_107034484 1.724 NM_001962
EFNA5
ephrin-A5
chr1_+_64709063 1.716 NM_020925
CACHD1
cache domain containing 1
chr3_-_87122936 1.713 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr8_+_60194328 1.713


chr6_-_132314004 1.713 NM_001901
CTGF
connective tissue growth factor
chr1_+_182622987 1.712 C1orf21
chromosome 1 open reading frame 21
chr18_-_22382497 1.710 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr7_+_33911636 1.699 NM_133468
BMPER
BMP binding endothelial regulator
chr3_-_87122958 1.688 VGLL3
vestigial like 3 (Drosophila)
chr9_-_79835970 1.680 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr12_-_29827952 1.657 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr19_-_36531958 1.653 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr12_+_56406296 1.651 LOC100130776
hypothetical LOC100130776
chr1_-_239587007 1.643 RGS7
regulator of G-protein signaling 7
chr9_+_123501186 1.642 DAB2IP
DAB2 interacting protein
chr4_-_122063118 1.633 NM_018699
PRDM5
PR domain containing 5
chr15_+_90738108 1.623 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr14_-_60817709 1.609 TMEM30B
transmembrane protein 30B
chr8_+_1936549 1.591 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr9_+_129893948 1.590 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chrX_+_66683075 1.583 AR
androgen receptor
chr8_-_13178327 1.579


chr15_+_45796802 1.571 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_-_166358951 1.570 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_-_45888259 1.565 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr5_-_146238336 1.561 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr10_-_118021532 1.545 NM_145793
GFRA1
GDNF family receptor alpha 1
chr19_-_19793512 1.504 NM_001099269
NM_001145404
ZNF506

zinc finger protein 506

chr5_+_17270781 1.487 BASP1
brain abundant, membrane attached signal protein 1
chr10_-_60792225 1.485 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr3_-_62835601 1.476


chr16_+_1524162 1.469 NM_024600
TMEM204
transmembrane protein 204
chr2_-_166359016 1.469 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr12_+_62524778 1.465 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr20_+_6696744 1.457 NM_001200
BMP2
bone morphogenetic protein 2
chr13_+_100902942 1.453 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr22_-_34566210 1.452 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_217206450 1.446 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr9_-_84867862 1.443 NM_152573
RASEF
RAS and EF-hand domain containing
chr5_-_146813343 1.436 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr10_-_79067400 1.431 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr7_+_27190688 1.427


chr5_-_59225377 1.426 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_37875538 1.421 NM_000514
GDNF
glial cell derived neurotrophic factor
chr10_-_60792666 1.418 NM_001143773
FAM13C
family with sequence similarity 13, member C
chr3_-_189354510 1.413 LOC339929
hypothetical LOC339929
chr2_-_166358792 1.410 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr11_-_88864061 1.400 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr8_+_106400322 1.388 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr12_-_93568336 1.376 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr9_-_109291130 1.375 KLF4
Kruppel-like factor 4 (gut)
chr7_-_27190882 1.369 HOXA11
homeobox A11
chr1_+_199884152 1.369 NAV1
neuron navigator 1
chr2_+_188864848 1.368 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr7_+_116099648 1.367 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr3_+_112273464 1.359 NM_015480
PVRL3
poliovirus receptor-related 3
chr10_-_105604942 1.340 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr9_-_83493415 1.338 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_+_188864898 1.335 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr20_+_32610161 1.332 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr5_+_92946348 1.325 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_-_109291866 1.318 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr9_-_129656581 1.297 ENG
endoglin
chr9_+_35528890 1.283 RUSC2
RUN and SH3 domain containing 2
chr2_-_225615556 1.283 NM_014689
DOCK10
dedicator of cytokinesis 10
chr11_+_94141151 1.268 NM_130847
AMOTL1
angiomotin like 1
chr15_+_41597097 1.268 NM_002373
MAP1A
microtubule-associated protein 1A
chr5_+_3649167 1.253 NM_024337
IRX1
iroquois homeobox 1
chr8_-_13178399 1.252 DLC1
deleted in liver cancer 1
chr13_-_71338558 1.251 DACH1
dachshund homolog 1 (Drosophila)
chr11_-_76800525 1.249 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr5_-_168660293 1.249 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr8_+_24827181 1.247 NEFM
neurofilament, medium polypeptide
chr14_+_37748345 1.243 SSTR1
somatostatin receptor 1
chr9_-_128924706 1.239 ANGPTL2
angiopoietin-like 2
chr19_-_9982041 1.235 NM_015719
COL5A3
collagen, type V, alpha 3
chr2_-_31215074 1.226 NM_024572
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr7_-_32076985 1.212 NM_001191056
NM_001191057
PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

chr6_-_80713589 1.206 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr6_+_74462654 1.202 CD109
CD109 molecule
chr7_-_124192265 1.202 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr10_-_79067552 1.198 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr18_+_19523526 1.196 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr14_-_22891263 1.196 NM_020372
SLC22A17
solute carrier family 22, member 17
chr2_+_23461802 1.190 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr2_-_40532651 1.188 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr9_-_129656778 1.181 ENG
endoglin
chr10_-_79067296 1.179 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_16530132 1.178 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr3_+_49002774 1.166 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr18_+_54681657 1.163 ZNF532
zinc finger protein 532
chr17_-_959007 1.157 NM_001092
ABR
active BCR-related gene
chr12_+_26239755 1.155 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr3_+_141136896 1.153 CLSTN2
calsyntenin 2
chr15_+_31390454 1.150 NM_001036
RYR3
ryanodine receptor 3
chr18_-_55515552 1.135 CCBE1
collagen and calcium binding EGF domains 1
chr7_-_27120015 1.132 HOXA3
homeobox A3
chr8_+_31616809 1.129 NM_013962
NRG1
neuregulin 1
chr20_+_55718718 1.126


chr13_-_43259032 1.125 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr9_-_34448477 1.124 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184944
NM_001184945
NM_147202
C9orf25






chromosome 9 open reading frame 25






chr6_+_74462630 1.123 CD109
CD109 molecule
chr8_+_24827173 1.122 NM_005382
NEFM
neurofilament, medium polypeptide
chrX_-_51256035 1.120 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr18_-_22383066 1.120 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr14_-_102593384 1.117 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr7_+_78920846 1.117 LOC100505881
hypothetical LOC100505881
chr9_-_128924782 1.113 ANGPTL2
angiopoietin-like 2
chr2_+_188865634 1.111 NM_016315
GULP1
GULP, engulfment adaptor PTB domain containing 1
chrX_+_17303458 1.111 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_72521079 1.110


chr20_+_55718619 1.110


chr16_+_22732982 1.110 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_-_192767844 1.109 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr11_+_110916629 1.108 LAYN
layilin
chr1_-_72520735 1.106 NM_173808
NEGR1
neuronal growth regulator 1
chr2_+_54537842 1.104 SPTBN1
spectrin, beta, non-erythrocytic 1
chr9_-_14303509 1.104 NFIB
nuclear factor I/B
chr4_+_153676857 1.100 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr9_-_129656830 1.100 NM_000118
NM_001114753
ENG

endoglin

chr10_+_106018620 1.100 NM_001191013
NM_183239
GSTO2

glutathione S-transferase omega 2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 4.05e-21 GO:0048731 system development
1.33 7.78e-21 GO:0048856 anatomical structure development
1.30 1.11e-18 GO:0007275 multicellular organismal development
1.27 1.06e-17 GO:0032502 developmental process
1.10 7.72e-16 GO:0009987 cellular process
1.43 3.87e-14 GO:0009653 anatomical structure morphogenesis
1.16 2.10e-13 GO:0050794 regulation of cellular process
1.34 5.23e-13 GO:0048523 negative regulation of cellular process
1.34 1.39e-12 GO:0030154 cell differentiation
1.41 1.51e-12 GO:0007399 nervous system development
1.33 3.00e-12 GO:0048869 cellular developmental process
1.14 3.84e-11 GO:0050789 regulation of biological process
1.30 4.04e-11 GO:0048519 negative regulation of biological process
1.49 1.41e-10 GO:0022008 neurogenesis
1.70 1.50e-10 GO:0072358 cardiovascular system development
1.70 1.50e-10 GO:0072359 circulatory system development
1.49 1.94e-10 GO:0048468 cell development
1.33 2.43e-10 GO:0048513 organ development
1.13 3.56e-10 GO:0065007 biological regulation
1.49 1.29e-09 GO:0048699 generation of neurons
1.22 2.60e-09 GO:0016043 cellular component organization
1.25 1.19e-08 GO:0071842 cellular component organization at cellular level
1.83 1.26e-08 GO:0001944 vasculature development
1.21 1.32e-08 GO:0071840 cellular component organization or biogenesis
1.57 2.86e-08 GO:0048666 neuron development
1.26 3.08e-08 GO:0048522 positive regulation of cellular process
1.78 4.31e-08 GO:0022603 regulation of anatomical structure morphogenesis
1.24 4.91e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.36 5.41e-08 GO:0051239 regulation of multicellular organismal process
1.61 6.37e-08 GO:0031175 neuron projection development
1.50 6.77e-08 GO:0030182 neuron differentiation
1.25 8.25e-08 GO:0044267 cellular protein metabolic process
1.60 8.87e-08 GO:0000904 cell morphogenesis involved in differentiation
1.17 1.00e-07 GO:0044260 cellular macromolecule metabolic process
1.51 1.96e-07 GO:0030030 cell projection organization
1.51 2.77e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.19 5.46e-07 GO:0023052 signaling
1.60 7.87e-07 GO:0048812 neuron projection morphogenesis
1.50 1.01e-06 GO:0032989 cellular component morphogenesis
1.71 1.02e-06 GO:0060284 regulation of cell development
1.22 2.27e-06 GO:0048518 positive regulation of biological process
1.47 2.30e-06 GO:0045595 regulation of cell differentiation
1.50 2.44e-06 GO:0000902 cell morphogenesis
1.41 2.56e-06 GO:0009888 tissue development
1.14 2.66e-06 GO:0032501 multicellular organismal process
1.40 2.98e-06 GO:0050793 regulation of developmental process
1.44 3.67e-06 GO:2000026 regulation of multicellular organismal development
1.54 3.70e-06 GO:0007417 central nervous system development
1.59 5.47e-06 GO:0007409 axonogenesis
1.58 5.86e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.41 8.59e-06 GO:0051128 regulation of cellular component organization
1.53 9.84e-06 GO:0048858 cell projection morphogenesis
1.72 1.30e-05 GO:0001568 blood vessel development
1.51 1.67e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.51 1.99e-05 GO:0032990 cell part morphogenesis
1.18 2.75e-05 GO:0007165 signal transduction
1.69 3.03e-05 GO:0061061 muscle structure development
1.53 3.30e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.46 3.40e-05 GO:0009887 organ morphogenesis
1.35 4.83e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.31 5.62e-05 GO:0009893 positive regulation of metabolic process
1.25 5.89e-05 GO:0006464 protein modification process
1.34 6.94e-05 GO:0007154 cell communication
1.76 7.02e-05 GO:0048514 blood vessel morphogenesis
1.42 8.02e-05 GO:0009790 embryo development
1.17 9.67e-05 GO:0031323 regulation of cellular metabolic process
1.31 9.94e-05 GO:0031325 positive regulation of cellular metabolic process
1.79 1.31e-04 GO:0007517 muscle organ development
1.13 1.35e-04 GO:0043170 macromolecule metabolic process
1.31 1.39e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.95 1.63e-04 GO:0060537 muscle tissue development
1.60 2.38e-04 GO:0001501 skeletal system development
1.34 3.08e-04 GO:0042127 regulation of cell proliferation
1.38 3.24e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.95 3.25e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.18 4.30e-04 GO:0019538 protein metabolic process
1.37 4.45e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.94 4.56e-04 GO:0022604 regulation of cell morphogenesis
1.16 4.58e-04 GO:0080090 regulation of primary metabolic process
1.25 6.36e-04 GO:0023051 regulation of signaling
1.57 6.69e-04 GO:0007411 axon guidance
1.22 6.87e-04 GO:0043412 macromolecule modification
1.37 7.32e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.15 7.79e-04 GO:0019222 regulation of metabolic process
1.35 9.56e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.30 9.66e-04 GO:0010646 regulation of cell communication
1.16 1.03e-03 GO:0060255 regulation of macromolecule metabolic process
3.05 1.13e-03 GO:0030199 collagen fibril organization
1.34 1.17e-03 GO:0009891 positive regulation of biosynthetic process
1.39 1.33e-03 GO:0051254 positive regulation of RNA metabolic process
1.49 1.46e-03 GO:0008285 negative regulation of cell proliferation
1.91 1.77e-03 GO:0014706 striated muscle tissue development
1.25 1.89e-03 GO:0009966 regulation of signal transduction
1.33 2.12e-03 GO:0040011 locomotion
1.30 2.15e-03 GO:0043067 regulation of programmed cell death
1.22 2.22e-03 GO:0007166 cell surface receptor linked signaling pathway
1.59 2.45e-03 GO:0051960 regulation of nervous system development
1.29 3.03e-03 GO:0042981 regulation of apoptosis
1.69 3.19e-03 GO:0045664 regulation of neuron differentiation
1.70 3.89e-03 GO:0048732 gland development
1.36 4.23e-03 GO:0019220 regulation of phosphate metabolic process
1.36 4.23e-03 GO:0051174 regulation of phosphorus metabolic process
1.29 4.43e-03 GO:0010941 regulation of cell death
1.36 4.52e-03 GO:0010628 positive regulation of gene expression
1.17 4.96e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 4.99e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.38 5.14e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.51 6.49e-03 GO:0007389 pattern specification process
1.54 6.80e-03 GO:0048729 tissue morphogenesis
1.45 6.87e-03 GO:0010648 negative regulation of cell communication
1.36 7.08e-03 GO:0042325 regulation of phosphorylation
1.44 7.30e-03 GO:0051094 positive regulation of developmental process
1.46 8.06e-03 GO:0016477 cell migration
1.77 8.39e-03 GO:0045165 cell fate commitment
1.84 8.61e-03 GO:0010975 regulation of neuron projection development
1.56 9.32e-03 GO:0035295 tube development
1.13 9.52e-03 GO:0051716 cellular response to stimulus
1.46 9.61e-03 GO:0009968 negative regulation of signal transduction
1.33 1.03e-02 GO:0007267 cell-cell signaling
1.97 1.03e-02 GO:0040013 negative regulation of locomotion
2.11 1.27e-02 GO:0048638 regulation of developmental growth
1.58 1.32e-02 GO:0050767 regulation of neurogenesis
1.54 1.38e-02 GO:0040012 regulation of locomotion
1.09 1.39e-02 GO:0044237 cellular metabolic process
1.53 1.65e-02 GO:0051270 regulation of cellular component movement
1.47 1.69e-02 GO:0090066 regulation of anatomical structure size
1.43 1.70e-02 GO:0023057 negative regulation of signaling
1.24 1.81e-02 GO:0035556 intracellular signal transduction
1.89 1.95e-02 GO:0010720 positive regulation of cell development
1.89 1.95e-02 GO:0035107 appendage morphogenesis
1.89 1.95e-02 GO:0035108 limb morphogenesis
1.82 2.24e-02 GO:0007050 cell cycle arrest
1.86 2.59e-02 GO:0048736 appendage development
1.86 2.59e-02 GO:0060173 limb development
1.68 3.18e-02 GO:0001525 angiogenesis
1.48 3.22e-02 GO:0045597 positive regulation of cell differentiation
1.24 3.24e-02 GO:0051641 cellular localization
1.72 3.24e-02 GO:0031344 regulation of cell projection organization
1.83 3.37e-02 GO:0035023 regulation of Rho protein signal transduction
1.77 3.55e-02 GO:0048705 skeletal system morphogenesis
1.38 3.68e-02 GO:0048585 negative regulation of response to stimulus
2.55 3.71e-02 GO:0034332 adherens junction organization
1.36 3.71e-02 GO:0006928 cellular component movement
1.45 3.74e-02 GO:0048598 embryonic morphogenesis
1.26 3.95e-02 GO:0051246 regulation of protein metabolic process
1.26 3.97e-02 GO:0032268 regulation of cellular protein metabolic process
1.47 4.43e-02 GO:0044057 regulation of system process
1.13 4.66e-02 GO:0051179 localization
1.26 5.00e-02 GO:0006793 phosphorus metabolic process
1.26 5.00e-02 GO:0006796 phosphate metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 1.85e-13 GO:0044424 intracellular part
1.08 5.29e-13 GO:0005622 intracellular
1.09 1.44e-08 GO:0043226 organelle
1.09 2.00e-08 GO:0043229 intracellular organelle
1.21 4.61e-08 GO:0043234 protein complex
1.10 5.49e-08 GO:0005737 cytoplasm
1.17 1.93e-06 GO:0032991 macromolecular complex
1.26 3.25e-05 GO:0005856 cytoskeleton
1.12 4.38e-05 GO:0044422 organelle part
1.11 8.45e-05 GO:0044446 intracellular organelle part
1.03 8.70e-05 GO:0044464 cell part
1.03 9.26e-05 GO:0005623 cell
1.79 1.09e-04 GO:0070161 anchoring junction
1.10 1.89e-04 GO:0044444 cytoplasmic part
1.49 1.95e-04 GO:0043005 neuron projection
1.80 2.51e-04 GO:0005912 adherens junction
1.07 2.92e-04 GO:0043227 membrane-bounded organelle
1.07 3.46e-04 GO:0043231 intracellular membrane-bounded organelle
2.24 4.56e-04 GO:0030426 growth cone
2.17 1.12e-03 GO:0030427 site of polarized growth
1.27 3.19e-03 GO:0005794 Golgi apparatus
1.35 3.80e-03 GO:0030054 cell junction
1.10 5.17e-03 GO:0005634 nucleus
1.35 5.33e-03 GO:0044431 Golgi apparatus part
1.18 6.08e-03 GO:0005829 cytosol
1.38 8.48e-03 GO:0000139 Golgi membrane
1.24 1.27e-02 GO:0044430 cytoskeletal part
1.39 2.13e-02 GO:0045202 synapse
1.14 2.51e-02 GO:0043228 non-membrane-bounded organelle
1.14 2.51e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.28 2.97e-02 GO:0044451 nucleoplasm part
1.75 4.13e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 7.42e-19 GO:0005515 protein binding
1.08 1.66e-11 GO:0005488 binding
1.50 1.46e-08 GO:0043565 sequence-specific DNA binding
1.35 5.87e-06 GO:0030528 transcription regulator activity
1.33 5.42e-05 GO:0001071 nucleic acid binding transcription factor activity
1.33 5.42e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.09 8.37e-04 GO:0019199 transmembrane receptor protein kinase activity
1.34 9.76e-04 GO:0019899 enzyme binding
1.38 4.34e-03 GO:0008092 cytoskeletal protein binding
2.13 6.39e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
1.51 1.23e-02 GO:0032403 protein complex binding
1.38 2.19e-02 GO:0019904 protein domain specific binding
1.16 2.46e-02 GO:0000166 nucleotide binding
1.56 3.51e-02 GO:0010843 promoter binding
1.73 4.56e-02 GO:0051020 GTPase binding
1.17 4.81e-02 GO:0017076 purine nucleotide binding