Motif ID: MAZ.p2

Z-value: 2.385


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)



Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_809879 4.611 NM_006651
CPLX1
complexin 1
chr8_+_144706699 4.486 NM_001166237
GSDMD
gasdermin D
chr20_+_61841662 4.258 SLC2A4RG
SLC2A4 regulator
chr7_+_5289079 4.180 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr19_-_55524445 4.135 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_+_659766 4.087 NM_001040134
NM_002579
PALM

paralemmin

chrX_+_138060 3.986 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr7_-_158073121 3.904 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr20_+_61841553 3.735 NM_020062
SLC2A4RG
SLC2A4 regulator
chr2_-_25328452 3.616 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr14_-_21064182 3.382 SALL2
sal-like 2 (Drosophila)
chr4_-_6253152 3.291 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr1_+_26895108 3.153 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr20_-_34635091 2.948


chr12_+_56291484 2.917 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chrX_+_9392980 2.908 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr1_-_32574185 2.905 NM_023009
MARCKSL1
MARCKS-like 1
chr2_+_42128521 2.880 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr11_+_56984702 2.859 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr19_-_2672337 2.779 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr16_+_84202515 2.652 NM_001134473
KIAA0182
KIAA0182
chr4_+_995395 2.641 FGFRL1
fibroblast growth factor receptor-like 1
chr22_+_48927610 2.496 NM_001164106
MOV10L1
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr16_-_2186465 2.483 NM_020764
CASKIN1
CASK interacting protein 1
chr6_+_99389318 2.452 POU3F2
POU class 3 homeobox 2
chr5_+_139008209 2.425 NM_016463
CXXC5
CXXC finger protein 5
chr20_-_61755145 2.387 NM_015894
STMN3
stathmin-like 3
chr17_-_39652449 2.376 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr13_-_113066366 2.299 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr9_+_70509925 2.267 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr15_-_62854749 2.250 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr18_-_28606839 2.250 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr5_-_134397740 2.241 NM_002653
PITX1
paired-like homeodomain 1
chr20_+_34635362 2.205 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr9_-_139564656 2.181 NM_001098537
NM_152286
PNPLA7

patatin-like phospholipase domain containing 7

chr13_-_113066202 2.180 GRTP1
growth hormone regulated TBC protein 1
chr2_-_74634569 2.168 NM_032603
LOXL3
lysyl oxidase-like 3
chr14_+_104261578 2.149 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr20_+_44083667 2.117 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr10_-_135021502 2.093 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr3_-_10522221 2.065 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr3_-_10522267 2.062 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr19_+_14405216 2.054 PKN1
protein kinase N1
chr17_-_53764867 2.031


chr2_+_72998111 2.029 NM_004097
EMX1
empty spiracles homeobox 1
chr20_-_44370537 1.994 CDH22
cadherin 22, type 2
chr17_-_39652391 1.993 UBTF
upstream binding transcription factor, RNA polymerase I
chr6_+_99389300 1.984 NM_005604
POU3F2
POU class 3 homeobox 2
chr1_-_149698516 1.977 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr3_-_10522340 1.967 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_38183480 1.960 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr3_-_47595190 1.956 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr16_+_49139694 1.949 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr12_+_93066370 1.947 NM_005761
PLXNC1
plexin C1
chr7_-_102044374 1.927 RASA4
RAS p21 protein activator 4
chr1_+_3679168 1.926 NM_001163724
LOC388588
hypothetical protein LOC388588
chr6_+_7052985 1.926 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr17_-_39632845 1.923 ATXN7L3
ataxin 7-like 3
chr2_+_220116986 1.910 NM_001005209
TMEM198
transmembrane protein 198
chr1_-_36562341 1.883 NM_018166
FAM176B
family with sequence similarity 176, member B
chr17_-_36938025 1.878 KRT19
keratin 19
chr11_+_47236072 1.856 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr2_+_220117009 1.851 TMEM198
transmembrane protein 198
chr17_+_35751796 1.827 NM_001024809
RARA
retinoic acid receptor, alpha
chr16_-_51138306 1.825 NM_001080430
TOX3
TOX high mobility group box family member 3
chr11_+_46358909 1.812 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr6_+_7052798 1.804 NM_001168344
RREB1
ras responsive element binding protein 1
chr2_-_200030944 1.778 NM_001172509
SATB2
SATB homeobox 2
chr2_+_149118791 1.777 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr5_+_139008139 1.777 CXXC5
CXXC finger protein 5
chr19_+_12810258 1.771 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr22_+_27931685 1.770 NM_133455
EMID1
EMI domain containing 1
chr13_+_99431417 1.765


chr17_+_72880831 1.752 NM_001113493
SEPT9
septin 9
chr19_+_45728270 1.734 SPTBN4
spectrin, beta, non-erythrocytic 4
chr7_-_102044419 1.719 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr4_+_995609 1.715 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr17_-_37586716 1.712 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr9_+_138726737 1.708 NM_152421
FAM69B
family with sequence similarity 69, member B
chr15_-_43267139 1.688 SHF
Src homology 2 domain containing F
chr17_+_45008473 1.676 NXPH3
neurexophilin 3
chr20_+_60918836 1.671 NM_001853
COL9A3
collagen, type IX, alpha 3
chr11_+_279113 1.663 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr7_-_149101227 1.655 NM_207336
ZNF467
zinc finger protein 467
chr5_+_139008091 1.650 CXXC5
CXXC finger protein 5
chr20_-_3097070 1.645 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr14_-_20562962 1.631 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr2_+_112372651 1.631 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr2_+_112372671 1.628 MERTK
c-mer proto-oncogene tyrosine kinase
chrX_+_118776572 1.627 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr19_-_48835783 1.626 NM_145296
CADM4
cell adhesion molecule 4
chr15_-_73530829 1.617 NM_015477
SIN3A
SIN3 homolog A, transcription regulator (yeast)
chr19_+_45728207 1.617 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr16_+_87765661 1.600 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr7_-_86942910 1.576 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr19_-_2653662 1.573 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr11_+_359723 1.566 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr7_+_150390566 1.563 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr16_+_1979959 1.549 NM_004209
SYNGR3
synaptogyrin 3
chr17_-_34014390 1.545 SRCIN1
SRC kinase signaling inhibitor 1
chr2_+_149119029 1.543 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_-_772966 1.535 LPPR3
lipid phosphate phosphatase-related protein type 3
chr6_+_169866714 1.535 LOC729088
hypothetical LOC729088
chr2_+_232281491 1.532 PTMA
prothymosin, alpha
chr6_+_37245860 1.532 NM_002648
PIM1
pim-1 oncogene
chr2_+_74635019 1.523 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr10_+_124885556 1.522 NM_001105574
HMX3
H6 family homeobox 3
chr2_-_174537354 1.518 SP3
Sp3 transcription factor
chr17_+_27617307 1.515 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr19_+_59061422 1.501 NM_001020820
MYADM
myeloid-associated differentiation marker
chr18_+_75261231 1.498 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr12_-_47679176 1.496 NM_015086
DDN
dendrin
chr6_+_44346457 1.494 NM_001137560
TMEM151B
transmembrane protein 151B
chr14_+_23508922 1.493 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr10_+_45189617 1.485 NM_000698
ALOX5
arachidonate 5-lipoxygenase
chr16_+_19087035 1.484 NM_016524
SYT17
synaptotagmin XVII
chr1_+_945331 1.482 NM_198576
AGRN
agrin
chr2_+_115635982 1.481 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr12_+_6808025 1.476 LEPREL2
leprecan-like 2
chr19_-_18409788 1.475 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr12_+_130945215 1.468 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr12_+_54700955 1.460 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr6_-_32265489 1.459 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr16_-_1369613 1.454 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr12_-_56418295 1.452 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr20_-_49592444 1.446 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr14_+_23907065 1.443 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr12_+_6290359 1.428 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr14_+_31615922 1.425 ARHGAP5
Rho GTPase activating protein 5
chr12_+_56230110 1.425 NM_004984
KIF5A
kinesin family member 5A
chr20_-_22512893 1.412 FOXA2
forkhead box A2
chr19_-_772913 1.411 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr17_+_45008175 1.408 NM_007225
NXPH3
neurexophilin 3
chr21_+_42946719 1.405 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr20_-_49592654 1.392 NM_012340
NM_173091
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr19_-_8581559 1.391 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr16_+_51722285 1.384 CHD9
chromodomain helicase DNA binding protein 9
chr10_-_103525646 1.384 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr12_-_61614930 1.384 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_+_50698169 1.382 HLF
hepatic leukemia factor
chr9_+_33807168 1.382 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr12_+_56230047 1.380 KIF5A
kinesin family member 5A
chr10_+_124897627 1.377 NM_005519
HMX2
H6 family homeobox 2
chr11_+_47958835 1.374 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr17_-_34157962 1.362 NM_007144
PCGF2
polycomb group ring finger 2
chrX_+_152643516 1.358 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr2_+_232281470 1.357 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr2_+_79593567 1.355 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr20_+_42807901 1.349 NM_022358
KCNK15
potassium channel, subfamily K, member 15
chr4_+_996251 1.348 NM_021923
FGFRL1
fibroblast growth factor receptor-like 1
chr19_+_1397268 1.345 APC2
adenomatosis polyposis coli 2
chr12_+_6290127 1.339 PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr7_-_100077072 1.338 NM_003227
TFR2
transferrin receptor 2
chr14_+_31615959 1.337 ARHGAP5
Rho GTPase activating protein 5
chr19_-_6453224 1.336 NM_006087
TUBB4
tubulin, beta 4
chr22_+_21742727 1.335 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr6_+_7053183 1.332 RREB1
ras responsive element binding protein 1
chr19_+_40451807 1.332 USF2
upstream transcription factor 2, c-fos interacting
chr22_-_40652724 1.324 NM_052945
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr17_+_75366524 1.321 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr2_+_119905812 1.312 NM_183240
TMEM37
transmembrane protein 37
chr16_+_2503676 1.307 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr16_+_29730909 1.300 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr17_+_72880967 1.298 SEPT9
septin 9
chr5_+_139008667 1.297 CXXC5
CXXC finger protein 5
chr14_-_26136799 1.297 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr16_+_1323627 1.292 BAIAP3
BAI1-associated protein 3
chr17_-_71352182 1.290 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr5_-_134397470 1.287 PITX1
paired-like homeodomain 1
chr1_-_40903897 1.286 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr10_+_94439658 1.285 NM_002729
HHEX
hematopoietically expressed homeobox
chr17_-_33982580 1.277 SRCIN1
SRC kinase signaling inhibitor 1
chr7_-_51351952 1.275 NM_015198
COBL
cordon-bleu homolog (mouse)
chr14_-_21074875 1.271 NM_005407
SALL2
sal-like 2 (Drosophila)
chr14_+_20608179 1.269 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr1_+_39319675 1.268 NM_012090
MACF1
microtubule-actin crosslinking factor 1
chr6_+_163755788 1.264 QKI
quaking homolog, KH domain RNA binding (mouse)
chr12_-_47679459 1.254 DDN
dendrin
chr2_-_25418249 1.251 NM_022552
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_+_16259812 1.247 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr10_-_104168890 1.246 NM_002779
PSD
pleckstrin and Sec7 domain containing
chr15_+_38550451 1.245 NM_130468
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr19_+_3310138 1.243 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr17_-_59131194 1.241 LIMD2
LIM domain containing 2
chr11_-_64268841 1.236 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_59131210 1.232 NM_030576
LIMD2
LIM domain containing 2
chr19_-_14062230 1.225 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr19_+_8180179 1.224 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr11_+_817584 1.219 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr16_+_65196125 1.215 CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr19_-_2653738 1.215 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr14_-_37134191 1.215 NM_004496
FOXA1
forkhead box A1
chr2_-_200030412 1.209 SATB2
SATB homeobox 2
chr16_-_30042030 1.207 MAPK3
mitogen-activated protein kinase 3
chr19_-_44060729 1.206 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr6_-_90178375 1.202 RRAGD
Ras-related GTP binding D
chr8_+_11599119 1.198 NM_002052
GATA4
GATA binding protein 4
chr10_+_22650145 1.198 BMI1
BMI1 polycomb ring finger oncogene
chr17_+_44429748 1.185 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr4_-_1156533 1.183 NM_012445
SPON2
spondin 2, extracellular matrix protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 1.83e-23 GO:0009987 cellular process
1.12 7.05e-16 GO:0044237 cellular metabolic process
1.11 1.18e-15 GO:0050794 regulation of cellular process
1.36 1.81e-15 GO:0010605 negative regulation of macromolecule metabolic process
1.10 2.25e-14 GO:0050789 regulation of biological process
1.33 4.99e-14 GO:0009892 negative regulation of metabolic process
1.09 5.74e-14 GO:0065007 biological regulation
1.42 1.19e-13 GO:0010629 negative regulation of gene expression
1.16 9.42e-13 GO:0060255 regulation of macromolecule metabolic process
1.15 1.16e-12 GO:0080090 regulation of primary metabolic process
1.13 1.77e-12 GO:0044260 cellular macromolecule metabolic process
1.19 5.37e-12 GO:0048519 negative regulation of biological process
1.32 5.46e-12 GO:0031324 negative regulation of cellular metabolic process
1.15 5.67e-12 GO:0031323 regulation of cellular metabolic process
1.20 1.02e-11 GO:0048523 negative regulation of cellular process
1.38 1.03e-11 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.14 1.06e-11 GO:0019222 regulation of metabolic process
1.17 1.23e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.09 1.85e-11 GO:0008152 metabolic process
1.30 2.75e-11 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.37 4.38e-11 GO:0010558 negative regulation of macromolecule biosynthetic process
1.37 1.06e-10 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 1.43e-10 GO:0045892 negative regulation of transcription, DNA-dependent
1.37 1.51e-10 GO:0051172 negative regulation of nitrogen compound metabolic process
1.39 3.10e-10 GO:0051253 negative regulation of RNA metabolic process
1.17 3.15e-10 GO:0010468 regulation of gene expression
1.16 5.56e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.15 6.87e-10 GO:0034641 cellular nitrogen compound metabolic process
1.09 7.57e-10 GO:0044238 primary metabolic process
1.34 1.04e-09 GO:0009890 negative regulation of biosynthetic process
1.34 1.44e-09 GO:0031327 negative regulation of cellular biosynthetic process
1.14 1.64e-09 GO:0006807 nitrogen compound metabolic process
1.16 3.45e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 7.86e-09 GO:0090304 nucleic acid metabolic process
1.17 1.16e-08 GO:0051252 regulation of RNA metabolic process
1.21 4.07e-08 GO:0007399 nervous system development
1.19 4.33e-08 GO:0016070 RNA metabolic process
1.13 6.63e-08 GO:0016043 cellular component organization
1.16 1.65e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.19 1.78e-07 GO:0034645 cellular macromolecule biosynthetic process
1.40 1.95e-07 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.15 2.03e-07 GO:0071842 cellular component organization at cellular level
1.10 2.13e-07 GO:0043170 macromolecule metabolic process
1.12 3.28e-07 GO:0071840 cellular component organization or biogenesis
1.19 4.16e-07 GO:0009059 macromolecule biosynthetic process
1.15 6.32e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.19 9.68e-07 GO:0023051 regulation of signaling
1.14 9.94e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.15 1.39e-06 GO:0044249 cellular biosynthetic process
1.15 1.43e-06 GO:0048522 positive regulation of cellular process
1.25 1.65e-06 GO:0022008 neurogenesis
1.25 1.76e-06 GO:0006351 transcription, DNA-dependent
1.16 2.03e-06 GO:0006355 regulation of transcription, DNA-dependent
1.14 3.40e-06 GO:0009058 biosynthetic process
1.14 3.46e-06 GO:0009889 regulation of biosynthetic process
1.14 4.29e-06 GO:0031326 regulation of cellular biosynthetic process
1.25 5.13e-06 GO:0048699 generation of neurons
1.13 5.67e-06 GO:0048518 positive regulation of biological process
1.11 1.37e-05 GO:0007275 multicellular organismal development
1.23 1.59e-05 GO:0032774 RNA biosynthetic process
1.27 1.88e-05 GO:0030182 neuron differentiation
1.37 2.03e-05 GO:0016568 chromatin modification
1.10 2.78e-05 GO:0032502 developmental process
1.18 2.92e-05 GO:0009966 regulation of signal transduction
1.21 3.14e-05 GO:0051246 regulation of protein metabolic process
1.16 3.58e-05 GO:0010467 gene expression
1.16 3.67e-05 GO:0006464 protein modification process
1.12 4.43e-05 GO:0048731 system development
1.15 1.10e-04 GO:0043412 macromolecule modification
1.10 1.16e-04 GO:0023052 signaling
1.21 1.32e-04 GO:0032268 regulation of cellular protein metabolic process
1.26 1.41e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.22 2.01e-04 GO:0048468 cell development
1.14 2.20e-04 GO:0030154 cell differentiation
1.12 2.68e-04 GO:0044267 cellular protein metabolic process
1.11 2.98e-04 GO:0048856 anatomical structure development
1.29 3.51e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.27 3.97e-04 GO:0048666 neuron development
1.14 4.47e-04 GO:0048869 cellular developmental process
1.42 7.64e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.46 9.52e-04 GO:0016569 covalent chromatin modification
1.18 1.13e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.45 1.35e-03 GO:0016570 histone modification
1.19 1.85e-03 GO:0007049 cell cycle
1.17 1.87e-03 GO:0009893 positive regulation of metabolic process
1.09 2.02e-03 GO:0051716 cellular response to stimulus
1.27 2.33e-03 GO:0031175 neuron projection development
1.10 3.06e-03 GO:0007165 signal transduction
1.22 4.95e-03 GO:0009790 embryo development
1.14 5.14e-03 GO:0006996 organelle organization
1.36 5.24e-03 GO:0051248 negative regulation of protein metabolic process
1.17 6.40e-03 GO:0031325 positive regulation of cellular metabolic process
1.29 9.91e-03 GO:0009792 embryo development ending in birth or egg hatching
1.27 1.14e-02 GO:0032583 regulation of gene-specific transcription
1.25 1.24e-02 GO:0019226 transmission of nerve impulse
1.25 1.24e-02 GO:0035637 multicellular organismal signaling
1.29 1.71e-02 GO:0043009 chordate embryonic development
1.35 1.85e-02 GO:0032269 negative regulation of cellular protein metabolic process
1.30 2.02e-02 GO:0070647 protein modification by small protein conjugation or removal
1.20 2.03e-02 GO:0012501 programmed cell death
1.17 2.17e-02 GO:0010646 regulation of cell communication
1.21 2.27e-02 GO:0045595 regulation of cell differentiation
1.20 2.27e-02 GO:0006915 apoptosis
1.22 2.27e-02 GO:0030030 cell projection organization
1.21 2.37e-02 GO:0010628 positive regulation of gene expression
1.19 2.52e-02 GO:0031399 regulation of protein modification process
1.29 3.13e-02 GO:0018193 peptidyl-amino acid modification
1.79 3.65e-02 GO:0032012 regulation of ARF protein signal transduction
1.18 3.76e-02 GO:0016265 death
1.18 3.94e-02 GO:0008219 cell death
1.64 4.64e-02 GO:0018394 peptidyl-lysine acetylation
1.17 4.85e-02 GO:0050793 regulation of developmental process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 8.93e-42 GO:0005622 intracellular
1.09 1.30e-40 GO:0044424 intracellular part
1.11 1.82e-27 GO:0005737 cytoplasm
1.10 9.90e-26 GO:0043227 membrane-bounded organelle
1.10 2.07e-25 GO:0043231 intracellular membrane-bounded organelle
1.09 8.97e-25 GO:0043226 organelle
1.09 9.62e-25 GO:0043229 intracellular organelle
1.14 5.13e-22 GO:0005634 nucleus
1.11 1.51e-15 GO:0044444 cytoplasmic part
1.22 2.35e-15 GO:0005829 cytosol
1.20 3.49e-13 GO:0044428 nuclear part
1.21 5.15e-12 GO:0031981 nuclear lumen
1.18 1.12e-11 GO:0070013 intracellular organelle lumen
1.18 2.65e-11 GO:0043233 organelle lumen
1.10 6.92e-11 GO:0044446 intracellular organelle part
1.17 1.58e-10 GO:0031974 membrane-enclosed lumen
1.10 3.10e-10 GO:0044422 organelle part
1.23 5.40e-10 GO:0005654 nucleoplasm
1.03 9.90e-09 GO:0005623 cell
1.03 1.19e-08 GO:0044464 cell part
1.24 2.13e-05 GO:0044451 nucleoplasm part
1.11 8.62e-05 GO:0043234 protein complex
1.10 1.04e-04 GO:0032991 macromolecular complex
1.24 5.76e-04 GO:0030054 cell junction
1.27 1.84e-03 GO:0045202 synapse
1.09 6.77e-03 GO:0043228 non-membrane-bounded organelle
1.09 6.77e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.21 1.26e-02 GO:0005694 chromosome
1.77 1.74e-02 GO:0008287 protein serine/threonine phosphatase complex
1.24 2.45e-02 GO:0043005 neuron projection
1.51 2.47e-02 GO:0016585 chromatin remodeling complex
1.11 4.80e-02 GO:0012505 endomembrane system

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 5.45e-30 GO:0005515 protein binding
1.07 1.16e-21 GO:0005488 binding
1.13 2.18e-08 GO:0003676 nucleic acid binding
1.24 1.29e-07 GO:0030528 transcription regulator activity
1.28 1.95e-07 GO:0019899 enzyme binding
1.28 1.08e-06 GO:0043565 sequence-specific DNA binding
1.23 1.32e-06 GO:0001071 nucleic acid binding transcription factor activity
1.23 1.32e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 1.78e-06 GO:0000166 nucleotide binding
1.14 6.96e-06 GO:0003677 DNA binding
1.34 2.96e-05 GO:0000988 protein binding transcription factor activity
1.34 2.96e-05 GO:0000989 transcription factor binding transcription factor activity
1.37 3.74e-05 GO:0016564 transcription repressor activity
1.33 4.00e-05 GO:0003712 transcription cofactor activity
1.30 1.34e-04 GO:0019904 protein domain specific binding
1.36 1.84e-04 GO:0008134 transcription factor binding
1.20 1.01e-03 GO:0003723 RNA binding
1.14 1.84e-03 GO:0032559 adenyl ribonucleotide binding
1.13 1.97e-03 GO:0032553 ribonucleotide binding
1.13 1.97e-03 GO:0032555 purine ribonucleotide binding
1.14 2.19e-03 GO:0030554 adenyl nucleotide binding
1.13 2.23e-03 GO:0017076 purine nucleotide binding
1.13 2.45e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.31 2.64e-03 GO:0016563 transcription activator activity
1.14 4.09e-03 GO:0005524 ATP binding
1.36 5.35e-03 GO:0003713 transcription coactivator activity
1.60 6.93e-03 GO:0031625 ubiquitin protein ligase binding
1.19 9.38e-03 GO:0042802 identical protein binding
1.08 9.43e-03 GO:0046872 metal ion binding
1.17 1.49e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.07 1.87e-02 GO:0043169 cation binding
1.07 2.19e-02 GO:0043167 ion binding
1.20 2.33e-02 GO:0046983 protein dimerization activity
1.28 3.24e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.21 3.45e-02 GO:0008092 cytoskeletal protein binding
1.17 4.36e-02 GO:0016301 kinase activity