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Motif ID: NANOG.p2

Z-value: 0.889

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_-_39189369	1.649		MKL1	megakaryoblastic leukemia (translocation) 1
chr6_+_34314545	1.598	NM_145905	HMGA1	high mobility group AT-hook 1
chr1_+_165565006	1.454		POU2F1	POU class 2 homeobox 1
chr2_+_17861266	1.453	NM_001105569	MSGN1	mesogenin 1
chr1_+_165564904	1.398	NM_001198783	POU2F1	POU class 2 homeobox 1
chr10_+_11246934	1.326	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chr7_+_50318801	1.285		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr2_+_157822355	1.265	NM_014568	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr3_-_57209319	1.253	NM_003865	HESX1	HESX homeobox 1
chr11_-_58736897	1.224	NM_001039396	MPEG1	macrophage expressed 1
chr1_+_196874839	1.182		PTPRC	protein tyrosine phosphatase, receptor type, C
chr3_+_161040439	1.166		SCHIP1	schwannomin interacting protein 1
chr7_-_13992351	1.157	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chrX_+_134482212	1.145	NM_182540	DDX26B	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_+_25096755	1.129		LRMP	lymphoid-restricted membrane protein
chr1_+_196874759	1.095	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr12_+_25096472	1.072	NM_006152	LRMP	lymphoid-restricted membrane protein
chr14_+_77939845	1.048	NM_004796	NRXN3	neurexin 3
chr15_+_56217686	1.009	NM_020980	AQP9	aquaporin 9
chr2_-_144994038	1.002		ZEB2	zinc finger E-box binding homeobox 2
chr12_+_45896511	0.998		FAM113B	family with sequence similarity 113, member B
chr11_-_83071084	0.974	NM_001142702	DLG2	discs, large homolog 2 (Drosophila)
chr3_+_161040343	0.963	NM_001197109	SCHIP1	schwannomin interacting protein 1
chr6_-_32605898	0.927	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr7_+_113853790	0.877	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr12_-_69434330	0.866		PTPRR	protein tyrosine phosphatase, receptor type, R
chr19_+_40632456	0.859	NM_005306	FFAR2	free fatty acid receptor 2
chr5_+_169713458	0.848	NM_001034838	KCNIP1	Kv channel interacting protein 1
chr3_+_123279439	0.833	NM_006889	CD86	CD86 molecule
chr2_+_108604111	0.832	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr6_-_161614962	0.826	NM_020133	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr1_+_180836050	0.815
chr7_-_92686773	0.797	NM_198151	HEPACAM2	HEPACAM family member 2
chr10_+_82290554	0.779	NM_001145719	SH2D4B	SH2 domain containing 4B
chr15_+_38849450	0.775	NM_001130448	C15orf62	chromosome 15 open reading frame 62
chr12_-_15005761	0.759	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr11_-_110755112	0.754		POU2AF1	POU class 2 associating factor 1
chr7_+_63411813	0.748		ZNF736	zinc finger protein 736
chr7_-_25234582	0.747	NM_022150	NPVF	neuropeptide VF precursor
chr7_+_128802719	0.745	NM_001130722	AHCYL2	adenosylhomocysteinase-like 2
chr10_-_13789628	0.738		FRMD4A	FERM domain containing 4A
chr6_+_88026338	0.728		ZNF292	zinc finger protein 292
chrX_+_134482387	0.723		DDX26B	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr7_-_107930170	0.720		PNPLA8	patatin-like phospholipase domain containing 8
chr18_+_19826734	0.713	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr19_-_46504831	0.713
chr6_-_32665409	0.712	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr2_+_170742900	0.698	NM_001083615 NM_001171642 NM_138995	MYO3B	myosin IIIB
chr15_-_91078307	0.677		FAM174B	family with sequence similarity 174, member B
chr4_+_71806538	0.651	NM_001037442 NM_014961	RUFY3	RUN and FYVE domain containing 3
chr13_+_108079570	0.647	NM_001198950	MYO16	myosin XVI
chr1_-_153109349	0.640	NM_002249	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr22_+_38652555	0.633		GRAP2	GRB2-related adaptor protein 2
chr8_-_40874485	0.633	NM_001135731 NM_024645	ZMAT4	zinc finger, matrin-type 4
chr12_+_45896318	0.629	NM_138371	FAM113B	family with sequence similarity 113, member B
chr1_-_30977931	0.621		LAPTM5	lysosomal protein transmembrane 5
chr1_+_50348052	0.600		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_39094787	0.592	NM_001040002	MEOX1	mesenchyme homeobox 1
chrX_-_135690699	0.591		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr7_+_18501876	0.591	NM_014707 NM_178423	HDAC9	histone deacetylase 9
chrX_-_19727828	0.588	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr2_-_68952006	0.588	NM_014482	BMP10	bone morphogenetic protein 10
chr6_+_34312633	0.585		HMGA1	high mobility group AT-hook 1
chr13_-_98708549	0.578	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr11_+_59979857	0.576	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr11_-_56951628	0.567	NM_017611	SLC43A3	solute carrier family 43, member 3
chr1_-_50661716	0.558	NM_032110	DMRTA2	DMRT-like family A2
chr13_-_40491405	0.556		ELF1	E74-like factor 1 (ets domain transcription factor)
chr17_-_1195096	0.554		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr11_-_118405288	0.548	NM_001164280	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr20_+_36365965	0.546	NM_001725	BPI	bactericidal/permeability-increasing protein
chr2_+_169465995	0.543	NM_001081686 NM_021176	G6PC2	glucose-6-phosphatase, catalytic, 2
chr3_+_35696119	0.542	NM_001025068 NM_001025069	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr12_-_107551783	0.536	NM_003006	SELPLG	selectin P ligand
chr5_-_169657395	0.534	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr9_-_14076901	0.529		NFIB	nuclear factor I/B
chrX_-_19727775	0.523		SH3KBP1	SH3-domain kinase binding protein 1
chr1_+_242283129	0.522	NM_006352	ZNF238	zinc finger protein 238
chr12_-_101398451	0.521		IGF1	insulin-like growth factor 1 (somatomedin C)
chr16_+_51690564	0.503		CHD9	chromodomain helicase DNA binding protein 9
chr15_-_75259714	0.503		PEAK1	NKF3 kinase family member
chr6_+_34312625	0.499	NM_145901 NM_145902	HMGA1	high mobility group AT-hook 1
chr7_+_116447527	0.492		ST7	suppression of tumorigenicity 7
chr5_+_137701122	0.479	NM_001135647	FAM53C	family with sequence similarity 53, member C
chr11_+_10433241	0.472	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr11_-_128217550	0.470	NM_000220	KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1
chr2_+_161980865	0.466	NM_006593	TBR1	T-box, brain, 1
chr4_+_174688183	0.461		NBLA00301	Nbla00301
chr8_+_67201684	0.459	NM_033058 NM_184085 NM_184086 NM_184087	TRIM55	tripartite motif containing 55
chr13_-_40454188	0.452		ELF1	E74-like factor 1 (ets domain transcription factor)
chr12_-_107551744	0.451		SELPLG	selectin P ligand
chr16_+_28797309	0.449	NM_004320 NM_173201	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chrX_+_41191630	0.449	NM_022567	NYX	nyctalopin
chr3_-_122862391	0.448		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr12_+_52105131	0.444		AMHR2	anti-Mullerian hormone receptor, type II
chr12_-_55614311	0.442	NM_148897	SDR9C7	short chain dehydrogenase/reductase family 9C, member 7
chr1_+_158636987	0.441	NM_020335	VANGL2	vang-like 2 (van gogh, Drosophila)
chr4_-_174687931	0.439	NM_021973	HAND2	heart and neural crest derivatives expressed 2
chr7_+_94135384	0.438		PEG10	paternally expressed 10
chr3_-_180467483	0.437	NM_001163677 NM_171828	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr12_+_79634820	0.437	NM_005593	MYF5	myogenic factor 5
chr21_-_38415273	0.436	NM_005867	DSCR4	Down syndrome critical region gene 4
chr21_-_35343331	0.434		RUNX1	runt-related transcription factor 1
chr12_-_101398429	0.432		IGF1	insulin-like growth factor 1 (somatomedin C)
chr17_-_44010543	0.424	NM_024015	HOXB4	homeobox B4
chr12_-_101398470	0.423		IGF1	insulin-like growth factor 1 (somatomedin C)
chr7_-_92615593	0.418	NM_152703	SAMD9L	sterile alpha motif domain containing 9-like
chr18_+_59726183	0.416		SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr6_+_32713160	0.415	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr18_+_18989786	0.415	NM_138375	CABLES1	Cdk5 and Abl enzyme substrate 1
chr12_-_101398503	0.409	NM_000618 NM_001111283 NM_001111285	IGF1	insulin-like growth factor 1 (somatomedin C)
chr12_-_51065629	0.408	NM_033045	KRT84	keratin 84
chr12_-_101398288	0.407		IGF1	insulin-like growth factor 1 (somatomedin C)
chr21_-_35343428	0.406		RUNX1	runt-related transcription factor 1
chr5_+_76470829	0.405
chr10_+_49279647	0.405	NM_002750 NM_139046 NM_139047 NM_139049	MAPK8	mitogen-activated protein kinase 8
chr6_+_34312906	0.401		HMGA1	high mobility group AT-hook 1
chr3_+_123385219	0.401	NM_000388	CASR	calcium-sensing receptor
chr3_-_122862447	0.400	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr1_+_154386358	0.399	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chrX_+_66705407	0.396	NM_001011645	AR	androgen receptor
chr5_-_88215034	0.395	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr4_-_123761615	0.393	NM_021803	IL21	interleukin 21
chr10_+_70517863	0.393		SRGN	serglycin
chr13_-_40491491	0.389	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr6_+_34312641	0.388		HMGA1	high mobility group AT-hook 1
chr21_-_35343065	0.386		RUNX1	runt-related transcription factor 1
chr17_-_37590910	0.386	NM_001524	HCRT	hypocretin (orexin) neuropeptide precursor
chr18_+_13601664	0.380	NM_001003674 NM_001003675	C18orf1	chromosome 18 open reading frame 1
chr7_+_18502342	0.377	NM_058176 NM_178425	HDAC9	histone deacetylase 9
chr21_-_35343448	0.372		RUNX1	runt-related transcription factor 1
chr11_+_65164167	0.370	NM_153253	SIPA1	signal-induced proliferation-associated 1
chr3_-_102522093	0.368	NM_016247	IMPG2	interphotoreceptor matrix proteoglycan 2
chr6_+_44076281	0.366	NM_001171992 NM_153246	C6orf223	chromosome 6 open reading frame 223
chr6_+_34312979	0.363		HMGA1	high mobility group AT-hook 1
chr1_+_196874867	0.362		PTPRC	protein tyrosine phosphatase, receptor type, C
chr1_-_149004852	0.358		CTSS	cathepsin S
chr10_+_11247243	0.357		CELF2	CUGBP, Elav-like family member 2
chr19_-_51829778	0.356	NM_033258	GNG8	guanine nucleotide binding protein (G protein), gamma 8
chr10_+_11247467	0.356		CELF2	CUGBP, Elav-like family member 2
chr10_-_21475493	0.353	NM_001010896 NM_001177483	C10orf113	chromosome 10 open reading frame 113
chr10_-_48036698	0.349	NM_016204	GDF2	growth differentiation factor 2
chr1_+_50347188	0.342		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_-_83354474	0.340	NM_052910	SLITRK1	SLIT and NTRK-like family, member 1
chr6_-_136888771	0.340	NM_001198608 NM_001198609 NM_001198611	MAP7	microtubule-associated protein 7
chr12_-_14024187	0.340	NM_000834	GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr13_+_48923688	0.336	NM_001160308	SETDB2	SET domain, bifurcated 2
chr3_+_69895651	0.336	NM_006722	MITF	microphthalmia-associated transcription factor
chr21_-_35343456	0.335	NM_001754	RUNX1	runt-related transcription factor 1
chr13_+_47948586	0.334		RB1	retinoblastoma 1
chr2_+_161981046	0.333		TBR1	T-box, brain, 1
chr4_+_169250281	0.329	NM_007193	ANXA10	annexin A10
chr15_-_53349775	0.327	NM_183234 NM_004580	RAB27A	RAB27A, member RAS oncogene family
chr21_-_35343500	0.325		RUNX1	runt-related transcription factor 1
chr22_+_20715340	0.322
chrX_-_137649180	0.322	NM_033642	FGF13	fibroblast growth factor 13
chr17_-_36181927	0.320	NM_181539	KRT26	keratin 26
chr8_-_86477585	0.319	NM_001128829 NM_001128830 NM_001128831 NM_001738	CA1	carbonic anhydrase I
chr17_-_10393664	0.318	NM_001100112 NM_017534	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr20_+_2224612	0.314	NM_003245	TGM3	transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr13_-_83354425	0.313		SLITRK1	SLIT and NTRK-like family, member 1
chr7_+_129771865	0.309	NM_001127441 NM_001127442 NM_080385	CPA5	carboxypeptidase A5
chr11_+_123986661	0.304	NM_052959	PANX3	pannexin 3
chr4_-_57242492	0.303	NM_001145460 NM_032495 NM_139212	HOPX	HOP homeobox
chr3_-_145049853	0.302	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_-_55090759	0.302	NM_007008	RTN4	reticulon 4
chr5_-_169657312	0.301		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_+_128795280	0.299		AHCYL2	adenosylhomocysteinase-like 2
chr11_-_57173823	0.299	NM_145008	YPEL4	yippee-like 4 (Drosophila)
chr10_+_11247419	0.297		CELF2	CUGBP, Elav-like family member 2
chr14_-_56342097	0.297	NM_172337	OTX2	orthodenticle homeobox 2
chr11_-_123799976	0.292	NM_001005196	OR8B4	olfactory receptor, family 8, subfamily B, member 4
chrX_+_135397790	0.291	NM_001727	BRS3	bombesin-like receptor 3
chr2_+_161981138	0.290		TBR1	T-box, brain, 1
chr7_+_128795178	0.289	NM_001130723	AHCYL2	adenosylhomocysteinase-like 2
chr12_-_16652202	0.289	NM_001001395	LMO3	LIM domain only 3 (rhombotin-like 2)
chr15_+_64481270	0.288		MAP2K1	mitogen-activated protein kinase kinase 1
chr8_-_102029997	0.287		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr11_-_17147863	0.285	NM_002645	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide
chr12_+_79625538	0.285	NM_002469	MYF6	myogenic factor 6 (herculin)
chr6_+_135544214	0.284		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr12_-_120725210	0.278		LOC338799	hypothetical LOC338799
chr12_-_51457371	0.277	NM_015848	KRT76	keratin 76
chr11_-_33870411	0.277	NM_005574	LMO2	LIM domain only 2 (rhombotin-like 1)
chr1_-_149004916	0.274	NM_004079	CTSS	cathepsin S
chrX_+_110252960	0.271	NM_001128168 NM_001128172 NM_001128173	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr5_+_156628929	0.271	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr5_-_169657192	0.269		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_-_26343139	0.269	NM_005320	HIST1H1D	histone cluster 1, H1d
chr17_+_4795128	0.269	NM_001193503 NM_001976 NM_053013	ENO3	enolase 3 (beta, muscle)
chr14_+_69307914	0.269		SRSF5	serine/arginine-rich splicing factor 5
chr5_+_176494690	0.268		NSD1	nuclear receptor binding SET domain protein 1
chr1_-_116185215	0.263	NM_005599	NHLH2	nescient helix loop helix 2
chr7_-_112513379	0.262	NM_001146266 NM_001146267	GPR85	G protein-coupled receptor 85
chr4_-_176971175	0.256	NM_201591	GPM6A	glycoprotein M6A
chr1_-_158098962	0.255	NM_001013661	VSIG8	V-set and immunoglobulin domain containing 8
chr3_+_2528272	0.255		CNTN4	contactin 4
chr3_-_120861959	0.253	NM_022135	POPDC2	popeye domain containing 2
chr7_-_99555399	0.253	NM_001190415	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_-_52281050	0.251	NM_001130059	ATF7	activating transcription factor 7

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.45	5.65e-10	GO:0032501	multicellular organismal process
1.76	5.84e-06	GO:0003008	system process
1.44	3.15e-05	GO:0032502	developmental process
1.43	2.26e-04	GO:0007275	multicellular organismal development
1.46	2.27e-04	GO:0048856	anatomical structure development
1.62	3.82e-04	GO:0048513	organ development
1.73	6.55e-04	GO:0050877	neurological system process
1.46	1.24e-03	GO:0048731	system development
2.03	2.92e-03	GO:0045595	regulation of cell differentiation
1.79	1.87e-02	GO:0050793	regulation of developmental process
3.34	2.31e-02	GO:0001503	ossification
1.48	2.64e-02	GO:0030154	cell differentiation
2.35	3.44e-02	GO:0045597	positive regulation of cell differentiation
2.13	3.89e-02	GO:0051094	positive regulation of developmental process
5.61	4.12e-02	GO:0051149	positive regulation of muscle cell differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.35	1.38e-04	GO:0071944	cell periphery
1.34	2.68e-04	GO:0005886	plasma membrane
8.90	4.28e-02	GO:0042613	MHC class II protein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.84	2.92e-04	GO:0001071	nucleic acid binding transcription factor activity
1.84	2.92e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.92	3.29e-03	GO:0043565	sequence-specific DNA binding