Motif ID: NFE2L2.p2

Z-value: 2.419


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2



Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_76538859 5.720 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr12_+_54361596 5.635 NM_152637
METTL7B
methyltransferase like 7B
chr12_+_54361685 5.563 METTL7B
methyltransferase like 7B
chr16_-_28528149 4.640 NM_177530
NM_177534
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr22_+_43451600 4.629 PRR5
proline rich 5 (renal)
chr19_-_54350457 4.540 NM_002152
HRC
histidine rich calcium binding protein
chr4_-_977163 4.538 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr16_-_28528780 3.987 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr22_+_43451351 3.801 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr19_-_53914768 3.409 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr16_-_28515195 3.303 NM_177528
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr7_+_37926943 3.276 EPDR1
ependymin related protein 1 (zebrafish)
chrX_-_100527799 3.250 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr6_-_31853027 3.021 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr16_+_2023279 2.954 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_+_72883128 2.931 NM_001305
CLDN4
claudin 4
chr1_-_45045543 2.924 NM_001013632
TCTEX1D4
Tctex1 domain containing 4
chr17_+_72883759 2.883 NM_001113494
SEPT9
septin 9
chr11_+_118463906 2.798 NM_001024382
HMBS
hydroxymethylbilane synthase
chr9_-_126309510 2.755 NM_004959
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr9_-_139042526 2.552 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chrX_+_153423652 2.501 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr22_-_39189369 2.494 MKL1
megakaryoblastic leukemia (translocation) 1
chr9_-_139042416 2.445 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_+_55398680 2.421 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr20_+_41621079 2.408 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr22_+_20316968 2.386 NM_152612
CCDC116
coiled-coil domain containing 116
chr7_+_139175420 2.333 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr20_+_41621119 2.320 SGK2
serum/glucocorticoid regulated kinase 2
chr22_+_19699441 2.313 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr16_+_30903963 2.247 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr1_+_153232685 2.233 NM_018655
LENEP
lens epithelial protein
chr1_-_156923111 2.228 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr9_-_115880372 2.199 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_22608252 2.198


chr22_+_21393107 2.183 IGLJ3
immunoglobulin lambda joining 3
chr16_+_51690564 2.150 CHD9
chromodomain helicase DNA binding protein 9
chr11_+_72660894 2.136 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_-_30032330 2.063 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr22_+_21484240 1.989


chrX_+_9391314 1.937 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr1_-_24307514 1.926 MYOM3
myomesin family, member 3
chr10_+_134751398 1.909 NM_001083909
GPR123
G protein-coupled receptor 123
chr6_-_35804337 1.835 NM_001145775
FKBP5
FK506 binding protein 5
chr16_+_88515917 1.834 NM_001197181
TUBB3
tubulin, beta 3
chr20_+_34206070 1.819 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_-_93030538 1.787 NM_005665
EVI5
ecotropic viral integration site 5
chr19_-_40696393 1.748 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr22_+_21495273 1.745


chr11_+_2881080 1.744 SLC22A18
solute carrier family 22, member 18
chr22_+_21370394 1.739 IGL@
immunoglobulin lambda locus
chr15_+_57691382 1.731 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr22_+_21116283 1.721


chr6_-_30792830 1.690 MDC1
mediator of DNA-damage checkpoint 1
chr17_-_53764867 1.683


chr22_-_25344037 1.670 CRYBB1
crystallin, beta B1
chr22_+_21094094 1.635


chr9_-_115880425 1.623 AMBP
alpha-1-microglobulin/bikunin precursor
chrX_-_154216929 1.612 NM_001289
CLIC2
chloride intracellular channel 2
chr6_-_32121784 1.607 NM_032470
TNXB
tenascin XB
chr9_-_115880494 1.601 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr14_+_38772870 1.600 NM_054024
MIA2
melanoma inhibitory activity 2
chr6_+_32003380 1.584 C2
complement component 2
chr22_+_20899155 1.584


chr9_-_115880366 1.579 AMBP
alpha-1-microglobulin/bikunin precursor
chr6_-_30793436 1.571 NM_014641
MDC1
mediator of DNA-damage checkpoint 1
chr16_-_66075216 1.567 NM_001138
AGRP
agouti related protein homolog (mouse)
chr16_-_1369613 1.566 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr16_+_28413421 1.545 NM_018690
APOBR
apolipoprotein B receptor
chr22_-_25343959 1.488 NM_001887
CRYBB1
crystallin, beta B1
chr17_+_71109734 1.484 MYO15B
myosin XVB pseudogene
chr17_-_30414789 1.484 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr14_+_102672745 1.482 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr9_-_115880281 1.460 AMBP
alpha-1-microglobulin/bikunin precursor
chr11_-_64906683 1.451 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr10_+_114126004 1.444 ACSL5
acyl-CoA synthetase long-chain family member 5
chr22_+_21079355 1.424


chr2_-_219881937 1.404 PTPRN
protein tyrosine phosphatase, receptor type, N
chr22_+_21407066 1.381


chr3_-_121883647 1.371 HGD
homogentisate 1,2-dioxygenase
chr15_+_57691272 1.363 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_-_180460372 1.361 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr20_+_48240705 1.352 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr2_+_37282516 1.340 LOC100505876
hypothetical LOC100505876
chr22_+_21359175 1.335 IGLV3-25
immunoglobulin lambda variable 3-25
chr17_-_25642962 1.306 NM_000386
BLMH
bleomycin hydrolase
chr7_+_111850367 1.306 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr4_-_80548378 1.294 NM_033214
GK2
glycerol kinase 2
chr1_+_26220852 1.293 NM_004455
EXTL1
exostoses (multiple)-like 1
chr13_+_112746908 1.289 MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_+_21042091 1.289 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr2_+_74635019 1.288 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr3_+_142569988 1.266 ZBTB38
zinc finger and BTB domain containing 38
chr9_+_139041736 1.254 NM_207511
C9orf139
chromosome 9 open reading frame 139
chr16_-_4778317 1.252 NM_001154458
NM_144605
SEPT12

septin 12

chr19_-_56260135 1.242 NM_015596
KLK13
kallikrein-related peptidase 13
chr22_+_21340757 1.227


chr20_+_48240772 1.226 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr14_-_22658078 1.216 NM_001805
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr18_+_19947314 1.195 TTC39C
tetratricopeptide repeat domain 39C
chr6_+_32229278 1.179 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr9_+_129962292 1.175 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr16_+_155972 1.169 NM_001003938
HBM
hemoglobin, mu
chr11_+_10434056 1.152 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr1_-_161105174 1.151 NM_178550
C1orf110
chromosome 1 open reading frame 110
chr22_+_18388656 1.151 C22orf25
chromosome 22 open reading frame 25
chr19_-_43926953 1.150 NM_144691
CAPN12
calpain 12
chr16_+_82544327 1.141 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr15_+_86983038 1.141 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr10_-_71562520 1.139 AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr12_+_54910767 1.130 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr17_+_77910411 1.125 NM_207459
TEX19
testis expressed 19
chr12_-_101835026 1.111 PAH
phenylalanine hydroxylase
chr11_+_46358909 1.108 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr7_+_44045202 1.105 FLJ35390
hypothetical LOC255031
chr1_-_158815850 1.095 CD84
CD84 molecule
chr11_+_10433241 1.087 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr1_+_26220895 1.087 EXTL1
exostoses (multiple)-like 1
chr6_-_36518643 1.079 NM_152990
PXT1
peroxisomal, testis specific 1
chr4_-_40212670 1.060 NM_019027
RBM47
RNA binding motif protein 47
chr16_+_30876115 1.053 NM_014712
SETD1A
SET domain containing 1A
chr1_-_176205672 1.051 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr5_+_179057968 1.049 CANX
calnexin
chr16_+_87765661 1.045 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr6_+_36518778 1.044 KCTD20
potassium channel tetramerisation domain containing 20
chr6_+_150112537 1.043 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr16_+_88696172 1.037 FAM157C
family with sequence similarity 157, member C
chr11_+_123600553 1.033 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chr2_+_27358800 1.026 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr6_+_36518521 1.016 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr3_-_121884091 1.005 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr3_+_112934016 1.005 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_-_39209075 1.000 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr5_+_179180509 0.993 SQSTM1
sequestosome 1
chr9_-_122728173 0.993 TRAF1
TNF receptor-associated factor 1
chr5_+_179180517 0.977 SQSTM1
sequestosome 1
chr1_-_176205970 0.973 SEC16B
SEC16 homolog B (S. cerevisiae)
chr10_-_71562602 0.970 NM_001198696
NM_032797
AIFM2

apoptosis-inducing factor, mitochondrion-associated, 2

chr1_+_109810743 0.968 SYPL2
synaptophysin-like 2
chr7_-_150352484 0.968 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr5_+_176807931 0.950 NM_001174102
PRR7
proline rich 7 (synaptic)
chr2_+_11597530 0.947 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr14_-_23847024 0.942 CIDEB
cell death-inducing DFFA-like effector b
chr5_+_179180447 0.940 NM_003900
SQSTM1
sequestosome 1
chr7_+_1050704 0.933


chr20_+_61337679 0.923 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr17_+_77261401 0.923 NM_004712
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr19_+_45564549 0.916 PLD3
phospholipase D family, member 3
chr2_+_119905812 0.915 NM_183240
TMEM37
transmembrane protein 37
chrX_-_152863251 0.900 NM_002910
RENBP
renin binding protein
chr6_+_32229599 0.898 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr7_-_100667750 0.894 NM_014343
CLDN15
claudin 15
chr12_-_54387934 0.893 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr17_+_14145051 0.872 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_-_7923464 0.864 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_+_3378030 0.863 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr15_-_81037554 0.862 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr5_+_61750467 0.862 NM_001134779
IPO11
importin 11
chr22_+_21053972 0.862


chr2_-_27967458 0.860 LOC100302650
hypothetical LOC100302650
chr17_-_35975227 0.855 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr4_-_174687104 0.850 HAND2
heart and neural crest derivatives expressed 2
chr14_-_21108714 0.846 NM_001005465
OR10G3
olfactory receptor, family 10, subfamily G, member 3
chr14_-_23846904 0.843 CIDEB
cell death-inducing DFFA-like effector b
chr8_-_143820825 0.838 NM_020427
SLURP1
secreted LY6/PLAUR domain containing 1
chr9_+_131291224 0.837 LOC100506190
hypothetical LOC100506190
chr22_+_21011653 0.835


chr17_-_70401299 0.834 NM_178128
FADS6
fatty acid desaturase domain family, member 6
chr1_-_6585485 0.826 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr20_+_34937928 0.826 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr8_-_59734975 0.826 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr16_-_68317945 0.823 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr6_+_150112511 0.820 NM_005389
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr2_-_70901186 0.812 NM_173535
CLEC4F
C-type lectin domain family 4, member F
chr10_+_114125927 0.811 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_-_54387732 0.810 ITGA7
integrin, alpha 7
chr17_+_44429748 0.810 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr16_+_30326864 0.807 ZNF771
zinc finger protein 771
chr6_+_31782618 0.807 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr16_+_85983375 0.805 MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr1_-_199259133 0.800 KIF21B
kinesin family member 21B
chr2_+_161873031 0.799 NM_005805
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr11_+_64079665 0.799 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr6_+_43373986 0.798 SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr5_-_176869440 0.798 DOK3
docking protein 3
chr14_-_20642214 0.793


chr17_+_77261440 0.790 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr20_-_61728866 0.786 GMEB2
glucocorticoid modulatory element binding protein 2
chr5_+_140594121 0.782 PCDHB18
protocadherin beta 18 pseudogene
chr6_-_28429950 0.776 NM_145909
ZNF323
zinc finger protein 323
chr10_-_99521701 0.774 NM_003015
SFRP5
secreted frizzled-related protein 5
chr14_+_22422270 0.772 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chr19_+_18560494 0.766 NM_001100418
NM_001100419
C19orf60

chromosome 19 open reading frame 60

chr17_-_71287417 0.762 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr8_-_59734957 0.758 NM_003580
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr5_+_132237253 0.758 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr10_+_114125955 0.752 ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_+_65869558 0.752 NM_001129727
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr6_+_32003180 0.746 NM_000063
NM_001145903
C2

complement component 2

chr6_-_110843432 0.745 NM_003649
NM_004032
DDO

D-aspartate oxidase


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.