Motif ID: NFIL3.p2

Z-value: 0.789


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated



Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_94442941 1.642 MCTP1
multiple C2 domains, transmembrane 1
chr4_-_74307637 1.473 ANKRD17
ankyrin repeat domain 17
chr5_-_94443300 1.430 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr3_-_159872960 1.321 NM_020169
LXN
latexin
chr22_-_34564611 0.987 RPL41P5
ribosomal protein L41 pseudogene 5
chr20_-_55718982 0.959 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr5_+_56507029 0.925 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr13_+_96672705 0.918 MBNL2
muscleblind-like 2 (Drosophila)
chrX_-_33139349 0.878 NM_004006
DMD
dystrophin
chr8_+_70567634 0.805 SULF1
sulfatase 1
chr5_+_36642213 0.803 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr4_+_170817787 0.790 CLCN3
chloride channel 3
chr5_+_36642424 0.754 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_28692122 0.746 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr20_+_33223434 0.701 NM_006404
PROCR
protein C receptor, endothelial
chr1_+_194887630 0.700 NM_000186
NM_001014975
CFH

complement factor H

chr8_+_70567581 0.664 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr8_+_94999167 0.622 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_-_31491102 0.619 NM_000379
XDH
xanthine dehydrogenase
chr1_-_6218576 0.574 ICMT
isoprenylcysteine carboxyl methyltransferase
chr4_-_153493133 0.574 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr13_-_43908937 0.573 TSC22D1
TSC22 domain family, member 1
chr4_-_96689373 0.557 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr2_-_31491057 0.537 XDH
xanthine dehydrogenase
chr13_+_96672541 0.503 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr2_+_178893216 0.497 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr1_-_6218554 0.492 ICMT
isoprenylcysteine carboxyl methyltransferase
chr1_-_177378801 0.490 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chrX_+_56772391 0.478 LOC550643
hypothetical LOC550643
chr7_+_134114701 0.472 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr1_+_210805319 0.462 NM_001030287
ATF3
activating transcription factor 3
chr10_+_135190855 0.458 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr4_-_153820535 0.454 NM_152680
TMEM154
transmembrane protein 154
chr11_+_68818175 0.452 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr1_-_42157077 0.447 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr7_+_142723340 0.443 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr9_+_126460511 0.443


chr4_+_47403107 0.438


chr17_-_36559579 0.433 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr11_+_93394025 0.411 NM_001098672
HEPHL1
hephaestin-like 1
chr14_+_101345878 0.408 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr3_+_130014957 0.402 RAB7A
RAB7A, member RAS oncogene family
chr1_+_65503011 0.386 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_-_28429950 0.378 NM_145909
ZNF323
zinc finger protein 323
chr11_+_9552809 0.375 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr12_-_44407515 0.370 LOC400027
hypothetical LOC400027
chr10_+_91077581 0.366 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_-_26665144 0.362 EVI2B
ecotropic viral integration site 2B
chr19_+_46286207 0.360 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr17_-_59204622 0.353 CCDC47
coiled-coil domain containing 47
chr16_-_53520208 0.352 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr4_+_74921136 0.352 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr4_+_88187215 0.351 AFF1
AF4/FMR2 family, member 1
chr9_+_17568952 0.341 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr2_+_169637255 0.327 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr10_-_64698831 0.324 NM_004241
JMJD1C
jumonji domain containing 1C
chr7_-_122627235 0.320 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr12_-_44407756 0.315 LOC400027
hypothetical LOC400027
chr3_+_62280435 0.307 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr8_-_102286695 0.306 ZNF706
zinc finger protein 706
chr21_-_14840506 0.303 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr17_-_36528113 0.290 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr2_-_213723298 0.287 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr17_+_55269974 0.284


chr9_+_27514311 0.281 NM_020124
IFNK
interferon, kappa
chr13_-_24644304 0.275 FAM123A
family with sequence similarity 123A
chrX_+_38548316 0.273 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr17_-_59204685 0.272 NM_020198
CCDC47
coiled-coil domain containing 47
chr2_-_133895795 0.269 NCKAP5
NCK-associated protein 5
chr1_-_245763763 0.266 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr3_+_44667504 0.261 ZNF35
zinc finger protein 35
chr12_-_51360439 0.259 NM_006121
KRT1
keratin 1
chr9_-_122679387 0.257 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr15_-_47042932 0.256 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr6_+_153060722 0.255 NM_025107
MYCT1
myc target 1
chr13_+_113546943 0.253 GAS6
growth arrest-specific 6
chr2_+_87536174 0.252 NCRNA00152
non-protein coding RNA 152
chr1_+_231007734 0.252 KIAA1383
KIAA1383
chr1_+_157246305 0.251 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr10_+_70517863 0.249 SRGN
serglycin
chr4_+_123873306 0.247 NM_001178007
NM_152618
BBS12

Bardet-Biedl syndrome 12

chr22_-_29197944 0.245 NM_174975
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr15_+_91244563 0.244 CHD2
chromodomain helicase DNA binding protein 2
chr1_+_231007260 0.244 NM_019090
KIAA1383
KIAA1383
chr15_+_91244422 0.241 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chrX_+_38548394 0.240 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr1_-_154988045 0.238 HDGF
hepatoma-derived growth factor
chrX_-_77037563 0.237 NM_032121
MAGT1
magnesium transporter 1
chr7_-_141048358 0.236 NM_001080392
KIAA1147
KIAA1147
chr19_+_46121963 0.235 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr7_-_44992729 0.233 C7orf40
chromosome 7 open reading frame 40
chr7_-_142369519 0.230 KEL
Kell blood group, metallo-endopeptidase
chr5_-_79982584 0.229 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr11_+_111552298 0.225 NM_001037290
BCO2
beta-carotene oxygenase 2
chr10_+_50557689 0.224 NM_001042427
NM_182554
C10orf53

chromosome 10 open reading frame 53

chr4_+_110574420 0.223 SEC24B
SEC24 family, member B (S. cerevisiae)
chr10_+_63331018 0.222 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr15_-_63871492 0.222 DENND4A
DENN/MADD domain containing 4A
chr10_+_70517823 0.221 NM_002727
SRGN
serglycin
chr4_+_3341521 0.219 NM_198227
RGS12
regulator of G-protein signaling 12
chr12_-_116283793 0.219 NM_000620
NOS1
nitric oxide synthase 1 (neuronal)
chr4_+_110574376 0.218 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chrX_+_38548373 0.217 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr12_-_69317441 0.216 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chrX_-_153428196 0.216 G6PD
glucose-6-phosphate dehydrogenase
chr11_+_65026382 0.216


chr14_-_66896167 0.215 NM_015994
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr8_-_17599438 0.215 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr7_+_143511480 0.212 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr8_-_130868315 0.207 NM_031415
GSDMC
gasdermin C
chr4_-_110574363 0.205 1/2-SBSRNA4
lncRNA_BC009800
chr12_+_50633430 0.205 NM_020327
ACVR1B
activin A receptor, type IB
chr3_+_156280604 0.204 NM_007288
MME
membrane metallo-endopeptidase
chr7_+_150321771 0.202 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr6_+_121798443 0.200 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr2_+_87536106 0.199 NCRNA00152
non-protein coding RNA 152
chr11_+_5667494 0.199 NM_006074
TRIM22
tripartite motif containing 22
chr9_-_122679283 0.194 PHF19
PHD finger protein 19
chr1_-_21373816 0.194 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr5_-_52441044 0.192 NM_004531
MOCS2
molybdenum cofactor synthesis 2
chr2_-_45648608 0.191 SRBD1
S1 RNA binding domain 1
chr9_-_99746923 0.190 NM_018437
HEMGN
hemogen
chr2_-_188021117 0.188 NM_005795
CALCRL
calcitonin receptor-like
chr6_+_7347878 0.187 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr13_-_24643778 0.185 NM_152704
NM_199138
FAM123A

family with sequence similarity 123A

chr3_+_42107711 0.185 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr11_-_10487212 0.184 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr17_-_46140015 0.183 NM_052855
ANKRD40
ankyrin repeat domain 40
chr7_-_142369534 0.181 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr18_+_75261231 0.176 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr7_+_89681069 0.174 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr10_+_98054074 0.172 NM_001017520
NM_004088
DNTT

deoxynucleotidyltransferase, terminal

chr3_+_191588354 0.172 NM_006580
CLDN16
claudin 16
chr1_+_176577228 0.171 NM_004841
RASAL2
RAS protein activator like 2
chr16_-_695719 0.168 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr1_+_7766966 0.167 PER3
period homolog 3 (Drosophila)
chr1_+_202033273 0.164 NM_001174108
ZBED6
zinc finger, BED-type containing 6
chr17_-_34263487 0.162 NM_000978
SNORA21
RPL23
small nucleolar RNA, H/ACA box 21
ribosomal protein L23
chr10_-_69125932 0.160 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr13_-_28190961 0.160 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr6_+_147568795 0.158 STXBP5
syntaxin binding protein 5 (tomosyn)
chr1_-_154987904 0.158 HDGF
hepatoma-derived growth factor
chr13_+_113546912 0.156 GAS6
growth arrest-specific 6
chr8_-_91066060 0.155 NM_002485
NBN
nibrin
chr2_+_161701711 0.155 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr15_-_56145140 0.155 NM_003888
NM_170696
ALDH1A2

aldehyde dehydrogenase 1 family, member A2

chr1_-_154988084 0.154 HDGF
hepatoma-derived growth factor
chr15_+_63701322 0.154 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr7_+_149778815 0.152 GIMAP8
GTPase, IMAP family member 8
chr3_-_145049853 0.152 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr5_-_14924555 0.150 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr4_-_24590867 0.148 NM_173463
CCDC149
coiled-coil domain containing 149
chr3_+_156280539 0.147 MME
membrane metallo-endopeptidase
chr1_+_144236346 0.146 NM_003637
ITGA10
integrin, alpha 10
chr2_+_201464884 0.143 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr5_-_127901376 0.142 FBN2
fibrillin 2
chr1_-_171838802 0.140 NM_178527
SLC9A11
solute carrier family 9, member 11
chrX_-_107569256 0.140 NM_001847
COL4A6
collagen, type IV, alpha 6
chr8_-_6407882 0.137 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr19_-_46080496 0.137 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr13_-_79810972 0.136 SPRY2
sprouty homolog 2 (Drosophila)
chr1_+_144236398 0.133 ITGA10
integrin, alpha 10
chr4_-_174774368 0.130 NM_006792
MORF4
mortality factor 4
chr8_+_24830492 0.129 NEFM
neurofilament, medium polypeptide
chrX_-_118583401 0.128 NM_001170570
NM_022101
CXorf56

chromosome X open reading frame 56

chrX_-_118583346 0.128 NM_001170569
CXorf56
chromosome X open reading frame 56
chr17_-_26672757 0.127 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr2_+_160180049 0.127 LOC643072
hypothetical LOC643072
chr1_+_115373937 0.127 NM_000549
TSHB
thyroid stimulating hormone, beta
chr7_-_112513379 0.126 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr2_+_148319033 0.126 NM_001616
ACVR2A
activin A receptor, type IIA
chr4_-_186815116 0.124 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chrX_+_38548016 0.124 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr6_-_134415311 0.123 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr3_+_44891101 0.122 NM_003241
TGM4
transglutaminase 4 (prostate)
chr17_-_26665194 0.121 EVI2B
ecotropic viral integration site 2B
chr8_-_117837240 0.121 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr1_+_7767300 0.120 NM_016831
PER3
period homolog 3 (Drosophila)
chr4_-_159311959 0.117 FAM198B
family with sequence similarity 198, member B
chr13_+_28900776 0.117 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr1_-_54183833 0.115 NM_016126
HSPB11
heat shock protein family B (small), member 11
chr1_+_161305188 0.114 NM_005613
RGS4
regulator of G-protein signaling 4
chr12_-_7487989 0.113 NM_174941
CD163L1
CD163 molecule-like 1
chr5_-_43593277 0.113 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chr12_+_52126131 0.113 PRR13
proline rich 13
chr13_-_45524846 0.112 NM_015070
ZC3H13
zinc finger CCCH-type containing 13
chr8_-_117837202 0.112 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr20_+_57729659 0.109 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr3_+_103029523 0.108 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr15_+_79276273 0.108 NM_001172128
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr12_+_123339662 0.107 NM_181709
FAM101A
family with sequence similarity 101, member A
chr7_+_115650240 0.107 NM_152829
TES
testis derived transcript (3 LIM domains)
chr8_+_69026895 0.107 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr6_+_26359805 0.107 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr11_+_65023038 0.106 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr12_+_109956210 0.106 NM_015267
CUX2
cut-like homeobox 2
chr13_+_113546897 0.104 GAS6
growth arrest-specific 6
chr1_+_177261798 0.104 FAM20B
family with sequence similarity 20, member B
chr18_+_75256702 0.104 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr8_-_72436832 0.103 EYA1
eyes absent homolog 1 (Drosophila)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.58 4.62e-03 GO:0005882 intermediate filament
3.30 6.67e-03 GO:0045111 intermediate filament cytoskeleton

Nothing significant found in function category.