Motif ID: NFIX.p2

Z-value: 2.087


Transcription factors associated with NFIX.p2:

Gene SymbolEntrez IDGene Name
NFIX 4784 nuclear factor I/X (CCAAT-binding transcription factor)



Activity profile for motif NFIX.p2.

activity profile for motif NFIX.p2


Sorted Z-values histogram for motif NFIX.p2

Sorted Z-values for motif NFIX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_88718167 3.077 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr17_-_25112393 3.056 SSH2
slingshot homolog 2 (Drosophila)
chr5_+_178919298 3.026 NM_001040451
NM_001040452
RUFY1

RUN and FYVE domain containing 1

chr4_+_158216631 2.893 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr15_+_61123327 2.543 TPM1
tropomyosin 1 (alpha)
chr9_-_21549696 2.495 LOC554202
hypothetical LOC554202
chr9_-_25668230 2.446 TUSC1
tumor suppressor candidate 1
chr4_-_75938710 2.395 NM_001729
BTC
betacellulin
chr21_+_32706615 2.366 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr17_-_68100537 2.356 LOC100499467
hypothetical LOC100499467
chr22_+_44828338 2.294


chr2_+_37425240 2.267 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr1_-_150233337 2.230 NM_002966
S100A10
S100 calcium binding protein A10
chr4_+_89597257 2.182 NM_016323
HERC5
hect domain and RLD 5
chr2_-_56266408 2.174 LOC100129434
hypothetical LOC100129434
chr8_-_101227203 2.154 NM_001029860
FBXO43
F-box protein 43
chr4_-_85638410 2.139 NM_006168
NKX6-1
NK6 homeobox 1
chr6_+_53767251 2.129 LRRC1
leucine rich repeat containing 1
chr3_-_197103848 2.061 TNK2
tyrosine kinase, non-receptor, 2
chr3_+_185762233 2.030 NM_004443
EPHB3
EPH receptor B3
chr10_+_102782151 1.995 SFXN3
sideroflexin 3
chr1_-_150232927 1.923 S100A10
S100 calcium binding protein A10
chr1_+_63832067 1.915 NM_001172819
PGM1
phosphoglucomutase 1
chr12_+_26239755 1.915 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr17_-_5428491 1.878 NM_001033053
NM_014922
NM_033004
NM_033006
NM_033007
NLRP1




NLR family, pyrin domain containing 1




chr1_-_150232900 1.863 S100A10
S100 calcium binding protein A10
chr9_+_111850770 1.848 AKAP2
A kinase (PRKA) anchor protein 2
chr3_+_129117007 1.846 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr9_+_70926205 1.844 TJP2
tight junction protein 2 (zona occludens 2)
chr5_+_122452739 1.839 NM_001136239
PRDM6
PR domain containing 6
chr1_+_156417302 1.831 CD1D
CD1d molecule
chr10_+_124210980 1.829 NM_002775
HTRA1
HtrA serine peptidase 1
chr10_-_128884411 1.785 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr9_+_111582317 1.777 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr14_+_51025604 1.764 NM_001042481
FRMD6
FERM domain containing 6
chr4_+_148621518 1.689 NM_001166055
NM_001957
EDNRA

endothelin receptor type A

chr8_-_41286088 1.661 NM_003012
SFRP1
secreted frizzled-related protein 1
chr21_-_27139563 1.657 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_+_70926009 1.619 NM_001170414
TJP2
tight junction protein 2 (zona occludens 2)
chr1_+_208569262 1.606 NM_001170580
HHAT
hedgehog acyltransferase
chr5_+_148941228 1.601 NM_001001669
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr9_+_111850698 1.598 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr1_+_238321794 1.598 NM_020066
FMN2
formin 2
chr1_+_208568811 1.557 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr14_+_58174489 1.556 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr1_+_219026661 1.552 NM_022746
MOSC1
MOCO sulphurase C-terminal domain containing 1
chr10_-_725522 1.543 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr15_-_30798417 1.540


chr9_-_129656413 1.538 ENG
endoglin
chr22_+_29974368 1.536 LIMK2
LIM domain kinase 2
chr3_+_191714533 1.530 NM_001167928
NM_001167929
NM_001167930
NM_001167931
NM_002182
NM_134470
IL1RAP





interleukin 1 receptor accessory protein





chr4_+_146622154 1.521 NM_005900
SMAD1
SMAD family member 1
chr10_+_122206455 1.495 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr12_+_81604752 1.488 TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr15_+_61122957 1.470 TPM1
tropomyosin 1 (alpha)
chr4_-_143987053 1.457 NM_001101669
NM_003866
INPP4B

inositol polyphosphate-4-phosphatase, type II, 105kDa

chr7_+_33911636 1.453 NM_133468
BMPER
BMP binding endothelial regulator
chr8_-_70908130 1.450 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr14_+_104785898 1.444 NM_033271
BTBD6
BTB (POZ) domain containing 6
chr5_+_94981735 1.427 NM_199243
GPR150
G protein-coupled receptor 150
chr3_+_49211936 1.424 NM_001135197
CCDC36
coiled-coil domain containing 36
chr5_+_96024434 1.420 CAST
calpastatin
chr14_+_104785936 1.405 BTBD6
BTB (POZ) domain containing 6
chr12_+_26239535 1.385 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr2_-_40532651 1.382 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr9_-_25668855 1.378 NM_001004125
TUSC1
tumor suppressor candidate 1
chr12_+_81605032 1.376 NM_152588
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr1_+_199975674 1.373 NAV1
neuron navigator 1
chr9_-_83493415 1.342 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr4_-_99798563 1.328 NM_005723
TSPAN5
tetraspanin 5
chr10_+_89409332 1.328 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr5_-_156935283 1.308


chr16_+_65765256 1.301 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr1_+_199975563 1.289 NM_001167738
NAV1
neuron navigator 1
chr14_+_23575460 1.263 NM_001082488
DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 1
chr5_-_156935317 1.248 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr14_-_104507862 1.242 AHNAK2
AHNAK nucleoprotein 2
chr13_-_100866839 1.236 NALCN
sodium leak channel, non-selective
chr4_-_83938920 1.227 NM_001037582
NM_024906
SCD5

stearoyl-CoA desaturase 5

chr21_-_27139143 1.219 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chrX_+_154264931 1.215 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr3_+_44571600 1.183 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr9_-_129656581 1.146 ENG
endoglin
chr10_-_91001496 1.141 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr9_-_112840801 1.138 LPAR1
lysophosphatidic acid receptor 1
chr4_+_148621694 1.136 EDNRA
endothelin receptor type A
chr14_-_99842519 1.134 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr18_-_24010944 1.131 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr22_+_29974314 1.126 NM_001031801
NM_016733
LIMK2

LIM domain kinase 2

chr4_+_166097548 1.112 NM_153027
C4orf39
chromosome 4 open reading frame 39
chr1_-_68470585 1.109 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr3_-_162305319 1.108 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr6_+_86216020 1.107 NM_002526
NT5E
5'-nucleotidase, ecto (CD73)
chr7_-_123460722 1.106 NM_001136002
TMEM229A
transmembrane protein 229A
chr9_+_77695334 1.103 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr1_+_77105746 1.095 NM_030965
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr1_-_234295293 1.095 NID1
nidogen 1
chr7_+_65307816 1.079 TPST1
tyrosylprotein sulfotransferase 1
chr6_-_153494076 1.056 NM_012419
RGS17
regulator of G-protein signaling 17
chr4_+_148621567 1.055 EDNRA
endothelin receptor type A
chr6_-_26125939 1.043 NM_005325
HIST1H1A
histone cluster 1, H1a
chr10_-_91001566 1.021 NM_000235
NM_001127605
LIPA

lipase A, lysosomal acid, cholesterol esterase

chr10_-_91001542 1.014 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr1_+_148521852 1.013 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr1_+_78858675 1.011 NM_006820
IFI44L
interferon-induced protein 44-like
chr10_-_91001531 1.009 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr11_-_11986704 1.001 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr1_+_77105709 1.000 ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr10_+_71232281 0.992 COL13A1
collagen, type XIII, alpha 1
chr6_-_150285838 0.981 NM_001001788
RAET1G
retinoic acid early transcript 1G
chr2_+_241023880 0.974


chr10_+_124211353 0.964 HTRA1
HtrA serine peptidase 1
chr1_+_43386180 0.954 NM_001101376
FAM183A
family with sequence similarity 183, member A
chr3_+_32408346 0.951 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr11_+_71613472 0.946 NM_001567
INPPL1
inositol polyphosphate phosphatase-like 1
chr9_-_129656778 0.945 ENG
endoglin
chr4_+_166097579 0.933 C4orf39
chromosome 4 open reading frame 39
chr1_-_234295117 0.930 NID1
nidogen 1
chr12_+_50271283 0.929 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr9_-_129656830 0.913 NM_000118
NM_001114753
ENG

endoglin

chr6_+_86216457 0.901 NT5E
5'-nucleotidase, ecto (CD73)
chr5_+_132111034 0.900 NM_001039780
CCNI2
cyclin I family, member 2
chr6_+_3696224 0.899


chr2_-_225615556 0.898 NM_014689
DOCK10
dedicator of cytokinesis 10
chr4_+_156899575 0.890 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr10_-_105982052 0.873 NM_025145
WDR96
WD repeat domain 96
chr5_-_80725704 0.873 NM_130767
ACOT12
acyl-CoA thioesterase 12
chr9_-_111300350 0.864 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr19_-_1188840 0.861 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr17_-_25587079 0.860 NM_001045
SLC6A4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr13_-_100866706 0.859 NM_052867
NALCN
sodium leak channel, non-selective
chr3_+_35656012 0.858 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_32408155 0.853 NM_138410
NM_181472
CMTM7

CKLF-like MARVEL transmembrane domain containing 7

chr11_+_101423378 0.851 NM_001195005
NM_032930
C11orf70

chromosome 11 open reading frame 70

chr8_-_70907957 0.847 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr19_-_61680510 0.833 NM_022103
ZNF667
zinc finger protein 667
chr1_+_31659246 0.829 NM_001199039
NM_018565
SERINC2

serine incorporator 2

chr5_+_15553768 0.823 FBXL7
F-box and leucine-rich repeat protein 7
chr1_-_206484258 0.819 NM_025179
PLXNA2
plexin A2
chr8_-_68037378 0.818 NM_001193502
TCF24
transcription factor 24
chr5_+_15553736 0.814 FBXL7
F-box and leucine-rich repeat protein 7
chr15_-_68971665 0.811 NM_020147
THAP10
THAP domain containing 10
chr5_+_15553539 0.806 FBXL7
F-box and leucine-rich repeat protein 7
chr4_+_14614462 0.798 CPEB2
cytoplasmic polyadenylation element binding protein 2
chr9_+_115382760 0.795 NM_021106
RGS3
regulator of G-protein signaling 3
chr9_-_122731263 0.779 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr1_-_234295099 0.776 NM_002508
NID1
nidogen 1
chr19_-_20540380 0.776 NM_001159293
ZNF737
zinc finger protein 737
chr5_+_178300799 0.773 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr1_-_19487790 0.769 NM_012067
AKR7A3
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr7_+_65307691 0.768 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr17_+_21220260 0.763 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr2_-_222871577 0.757 NM_000438
NM_001127366
NM_013942
NM_181457
NM_181458
NM_181459
NM_181460
NM_181461
PAX3







paired box 3







chr20_-_3696344 0.754 NM_001039140
C20orf27
chromosome 20 open reading frame 27
chr16_-_11587647 0.753 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr3_-_50371896 0.751 TMEM115
transmembrane protein 115
chr12_+_106236281 0.749 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr4_+_77446700 0.745 NM_003943
STBD1
starch binding domain 1
chr5_+_15553288 0.738 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr11_+_122258600 0.737 NM_024806
NM_199124
C11orf63

chromosome 11 open reading frame 63

chr10_+_73393998 0.732 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr17_-_78249750 0.732 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr5_+_140767953 0.730 NM_018926
NM_032100
PCDHGB6

protocadherin gamma subfamily B, 6

chr1_-_72520735 0.728 NM_173808
NEGR1
neuronal growth regulator 1
chr21_+_25856311 0.725 MIR155HG
MIR155 host gene (non-protein coding)
chr1_-_234294997 0.723 NID1
nidogen 1
chr11_+_125262164 0.713 NM_001134793
HYLS1
hydrolethalus syndrome 1
chr3_-_50371960 0.712 TMEM115
transmembrane protein 115
chr2_+_241023703 0.710 NM_002081
GPC1
glypican 1
chr19_-_19599973 0.701 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr15_+_38849450 0.700 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr12_+_62523648 0.694


chr8_+_24827173 0.691 NM_005382
NEFM
neurofilament, medium polypeptide
chr17_-_74432800 0.688 TIMP2
TIMP metallopeptidase inhibitor 2
chr10_+_17312654 0.688 VIM
vimentin
chr5_+_76418545 0.683 LOC728723
hypothetical LOC728723
chr10_+_135057597 0.682 NM_138384
MTG1
mitochondrial GTPase 1 homolog (S. cerevisiae)
chr3_-_50371934 0.682 NM_007024
TMEM115
transmembrane protein 115
chr5_-_37285160 0.674 NM_023073
C5orf42
chromosome 5 open reading frame 42
chr17_+_4922445 0.669 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr5_+_76418214 0.668 LOC728723
hypothetical LOC728723
chr13_+_27392136 0.667 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr14_-_99695684 0.663 NM_206918
DEGS2
degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)
chr10_-_45488162 0.655 NM_001128324
NM_174890
ANUBL1

AN1, ubiquitin-like, homolog (Xenopus laevis)

chr10_-_100164877 0.653 NM_032709
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr12_+_6179736 0.648 NM_001769
CD9
CD9 molecule
chr1_+_20788027 0.646 NM_001785
CDA
cytidine deaminase
chr10_+_133850325 0.641 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr4_-_76774594 0.639 NM_003948
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr4_+_3264509 0.635 RGS12
regulator of G-protein signaling 12
chr6_-_55551812 0.634 NM_001042406
NM_019036
HMGCLL1

3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1

chr17_+_72795567 0.629 NM_001113492
SEPT9
septin 9
chr4_-_111777651 0.629 PITX2
paired-like homeodomain 2
chr1_+_31658549 0.625 NM_178865
SERINC2
serine incorporator 2
chr11_-_75057299 0.625 MAP6
microtubule-associated protein 6
chr1_-_94779727 0.622 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr1_-_151855413 0.621 NM_020672
S100A14
S100 calcium binding protein A14
chr10_+_51497716 0.621 FAM21A
family with sequence similarity 21, member A
chr4_-_111777584 0.620 PITX2
paired-like homeodomain 2
chr2_-_127694123 0.615 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 2.41e-03 GO:0005737 cytoplasm
1.16 5.20e-03 GO:0044444 cytoplasmic part

Nothing significant found in function category.